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The map label for this gene is ycgJ [H]

Identifier: 78044795

GI number: 78044795

Start: 481153

End: 481767

Strand: Direct

Name: ycgJ [H]

Synonym: CHY_0555

Alternate gene names: 78044795

Gene position: 481153-481767 (Clockwise)

Preceding gene: 78044881

Following gene: 78043460

Centisome position: 20.04

GC content: 41.95

Gene sequence:

>615_bases
TTGTTAGAAAAGATTATAGCTCGTTACGAAAAGGAATCCGGTGAAGGTCTTTCCTGCGGCAACAATATAGCGGTGGGAAG
CTTAAAACCGGGCATGATAGTACTGGATTTGGGATGCGGCAATGGGGGAGAAACAATTAGAGCTGCACAAATTGTTGCTC
CGGGGTTTGCCGTTGGACTTGATATTACCGAAAAACTTTTAGAAAAAGGGCAAAAAAAAGCCCGGGAACAGGGAGTTAAA
AACGTTGTTTTTATCAAAGGTGAAATAGAAAACTTACCCTTTGTCGGGGAAAGCTTTGATGTGGTAATTTCCAATTGTGC
TTTAAATCATGCCCGGGATAAGTTAAAAGTATACCGGGAGATTTACAGGGTTTTAAAGGAAGACGGCTATTTTATTGTAT
CCGACCCGGTTAGCCTGGTGGAACTTCCACCGGAAATAAAAAATAACGAGGAACTCTGGGCCCAGTGTTTTGCTGGAGCG
GAAGAAGAGTCGAAGTATTTACGCTACATTATCGAAGCCGGGTTTACTTTGGAGATTTTAAAAAGAAGGGAATACGAAAA
AAACGGCTATCCTTTTGCCAGTCTTACCATTAAAGGTACCAAGAAAAGGAGGTGA

Upstream 100 bases:

>100_bases
AGACGATGAATATTACATCGGACCCTCCTGTCAGGGGTGCGGTTACTGCCGTAAGTTTTGCCCTTATAATGCTATTGAGC
TTACCAGTTAGGTGATTAAA

Downstream 100 bases:

>100_bases
AATCATGAAAGCTATTACCAGAAAACAAACCGCAAAGTGTGACTACAACCTTGGGTGCGCTCAGTGCTGCTCCAAGACCT
CCAAGGTGGTTGCGGGTTGC

Product: UbiE/COQ5 family methlytransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MLEKIIARYEKESGEGLSCGNNIAVGSLKPGMIVLDLGCGNGGETIRAAQIVAPGFAVGLDITEKLLEKGQKKAREQGVK
NVVFIKGEIENLPFVGESFDVVISNCALNHARDKLKVYREIYRVLKEDGYFIVSDPVSLVELPPEIKNNEELWAQCFAGA
EEESKYLRYIIEAGFTLEILKRREYEKNGYPFASLTIKGTKKRR

Sequences:

>Translated_204_residues
MLEKIIARYEKESGEGLSCGNNIAVGSLKPGMIVLDLGCGNGGETIRAAQIVAPGFAVGLDITEKLLEKGQKKAREQGVK
NVVFIKGEIENLPFVGESFDVVISNCALNHARDKLKVYREIYRVLKEDGYFIVSDPVSLVELPPEIKNNEELWAQCFAGA
EEESKYLRYIIEAGFTLEILKRREYEKNGYPFASLTIKGTKKRR
>Mature_204_residues
MLEKIIARYEKESGEGLSCGNNIAVGSLKPGMIVLDLGCGNGGETIRAAQIVAPGFAVGLDITEKLLEKGQKKAREQGVK
NVVFIKGEIENLPFVGESFDVVISNCALNHARDKLKVYREIYRVLKEDGYFIVSDPVSLVELPPEIKNNEELWAQCFAGA
EEESKYLRYIIEAGFTLEILKRREYEKNGYPFASLTIKGTKKRR

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Homo sapiens, GI109389364, Length=138, Percent_Identity=40.5797101449275, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI48994983, Length=114, Percent_Identity=35.9649122807018, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 22762; Mature: 22762

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKIIARYEKESGEGLSCGNNIAVGSLKPGMIVLDLGCGNGGETIRAAQIVAPGFAVGL
CHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEEEECCCCCCCCEEEEEEECCCEEECH
DITEKLLEKGQKKAREQGVKNVVFIKGEIENLPFVGESFDVVISNCALNHARDKLKVYRE
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IYRVLKEDGYFIVSDPVSLVELPPEIKNNEELWAQCFAGAEEESKYLRYIIEAGFTLEIL
HHHHHHHCCCEEEECCHHEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHH
KRREYEKNGYPFASLTIKGTKKRR
HHHHHCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MLEKIIARYEKESGEGLSCGNNIAVGSLKPGMIVLDLGCGNGGETIRAAQIVAPGFAVGL
CHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEEEECCCCCCCCEEEEEEECCCEEECH
DITEKLLEKGQKKAREQGVKNVVFIKGEIENLPFVGESFDVVISNCALNHARDKLKVYRE
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IYRVLKEDGYFIVSDPVSLVELPPEIKNNEELWAQCFAGAEEESKYLRYIIEAGFTLEIL
HHHHHHHCCCEEEECCHHEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHH
KRREYEKNGYPFASLTIKGTKKRR
HHHHHCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]