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The map label for this gene is hdrA2 [H]

Identifier: 78044755

GI number: 78044755

Start: 820505

End: 822487

Strand: Direct

Name: hdrA2 [H]

Synonym: CHY_0930

Alternate gene names: 78044755

Gene position: 820505-822487 (Clockwise)

Preceding gene: 78044470

Following gene: 78043978

Centisome position: 34.17

GC content: 50.28

Gene sequence:

>1983_bases
ATGAAGAGAATAGGAGTATTTGTCTGCTGGTGCGGTTCTAATATCGGTGGGGTTGTGGATGTCCCGAGAGTAGCTGAGGC
GGCAAAGGAAATGCCCAATGTGGTGTTTGCTACCGATTATAAATACATGTGTTCGGAGCCCGGCCAGGAGCTAATTATCA
AAGCGGCTAAAGAGCACAACTTGGACCGGGTCGTGGTGGCATCCTGCTCGCCGCGTTTGCATGAACAAACCTTTAGAAAG
GCTGCCGAACGGGCAGGACTTAACCCCTATATGTTTGAAATGGCCAACATCCGGGAGCACGTTTCCTGGGTCCATGCTCA
AGAAAAAGAGAAAGCGACCGAAAAGGCAATTGAACTGGTCAGACGGGCTGTCTTTAAGGCTGCACGCTTGGAGCCCCTTT
ACAAATCAGCCATCGGTATCACAAAAAAAGCCCTGGTCATCGGTGGTGGTATTGCCGGGATTCAGGCAGCTTTGGATATT
GCCGATGCCGGGTATCAGGTTATATTGGTGGAAAAGGAGCCAACCATTGGCGGGAAAATGGCGCAGCTCGATAAAACCTT
CCCAACCTTAGACTGTTCCAGCTGAATATCTACCCCGAAGATGGCGGCTGCGGCGCAGCACCCAAACATTAAGCTTTATA
CTTATGCGGAAGTTACCGAAGTTTCCGGTTATATTGGTAATTTTGAAGTTACCATTAAGCAAAAGGCCAAATCGGTGGAC
CATAATAAATGTACCGGATGCGGTACTTGCTGGGAAAAATGTCCCACCAAAGTTGATAGTGAATTTGACTTAGGGCTTGG
TAAACGGAAAGCTATTTACATTCCTTTTGCCCAGGCGGTTCCCAATAAGCCGGTTATTGACCGTACTACCTGCCGGCAAT
TTACCAAAGGCAAGTGCGGCGTTTGCCAGAAAGTTTGTCCTACCGGTGCTGTAGATTACGACCAGCAGGATGAATATATT
AAAGAAAAAGTCGGAGCCATTATCATGGCTACCGGCTATGACCTGTTTGAGTGGGAAAAAGTCTACGGTGAGTACGGTTA
CGGTCAGTATCCGGACGTGATTACCGGATTACATTTTGAGCGGATGGCCAGTGCTTCCGGTCCTACCGGTGGCAAGATTA
TTCGTCCGTCCGATGGCAAAGAGCCCAAAACGGTTGTATTTATTAAATGCGTTGGTTCAAGGGATGACCAAAAAGGCAAG
AGCTACTGCTCCCGGGCCTGCTGTATGTATACTGCCAAGCATGCGCACCAGGTTTTGGAAAAGATTCCCGGAGCGCAGGT
GTATATCTTCTACATGGACGTTCGGACAGCCGGCAAGATGTACGAAGAATTTTACGCCAAAACCCTGGAAGATGGTGCCC
AGTACATTCGCGGGCGAGTATCGAAGATTTATCCTTTAGGAGATAAATTAATTGTTCGCGGAGCTGACACCCTGGCCGGA
GTTCCGGTGGAAATTGAAGCCGACCTGGTGGTCTTGGCCACCGCTATGGTACCGGCCAAGGGGTCGGAGGAAATTGCCAA
AATTGTCGGCTTTTCTTTAGATAAAGATGGCTTCTTCCAGGAAGCTCACCCCAAGCTTGGGCCGGTGGAGACCACTACCG
GAGGCGTATTTTTAGCCGGCGCTTGCCAGGGGCCCAAGGATATTCCGGACACGGTAGCGCAGGCCAGTGCAGCGGCGGCC
AAGGTTATCGGGCTTTTATCCAAGGATCAGTTAGCTGCCGAGCCAATCGTCAGCCAGGTTAACGAAGCACTTTGTTCCGG
TTGCGAATTATGTAAACCCATTTGTCCGTATAAGGCTATCGACATGAAGAAGATTACCGAACGGGTTCACGGTAAGGTTA
TCGAACGCACCGTGGCAACGGTTAACACCAGTCTGTGTCAGGGTTGCGGAGCCTGTACCGTTGCCTGCCGGGTAGGAGCC
CTTAACCTCAAAGGCTTTACCAACGAACAGCTCCTGGCGGAGGTGGAAGCAATATGTCTGTAG

Upstream 100 bases:

>100_bases
CCGAATTAATTGGTTTAGCTCTCGGTTTAAAACCGGAGGAGCTTGGCTTAAATACCCACTTTGTTAGCACCAAAAAAGTA
CTGGAGTGGAGAGATGCACG

Downstream 100 bases:

>100_bases
AGCAAAACTTTGAGCCGAAAATAATAGCGTTCTTTTGCAACTGGTGTAGCTACGCCGGAGCAGACCTGGCCGGGGTTAGC
CGGATGCAGTACCCCACCAA

Product: heterodisulfide reductase subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MKRIGVFVCWCGSNIGGVVDVPRVAEAAKEMPNVVFATDYKYMCSEPGQELIIKAAKEHNLDRVVVASCSPRLHEQTFRK
AAERAGLNPYMFEMANIREHVSWVHAQEKEKATEKAIELVRRAVFKAARLEPLYKSAIGITKKALVIGGGIAGIQAALDI
ADAGYQVILVEKEPTIGGKMAQLDKTFPTLDCSSUISTPKMAAAAQHPNIKLYTYAEVTEVSGYIGNFEVTIKQKAKSVD
HNKCTGCGTCWEKCPTKVDSEFDLGLGKRKAIYIPFAQAVPNKPVIDRTTCRQFTKGKCGVCQKVCPTGAVDYDQQDEYI
KEKVGAIIMATGYDLFEWEKVYGEYGYGQYPDVITGLHFERMASASGPTGGKIIRPSDGKEPKTVVFIKCVGSRDDQKGK
SYCSRACCMYTAKHAHQVLEKIPGAQVYIFYMDVRTAGKMYEEFYAKTLEDGAQYIRGRVSKIYPLGDKLIVRGADTLAG
VPVEIEADLVVLATAMVPAKGSEEIAKIVGFSLDKDGFFQEAHPKLGPVETTTGGVFLAGACQGPKDIPDTVAQASAAAA
KVIGLLSKDQLAAEPIVSQVNEALCSGCELCKPICPYKAIDMKKITERVHGKVIERTVATVNTSLCQGCGACTVACRVGA
LNLKGFTNEQLLAEVEAICL

Sequences:

>Translated_660_residues
MKRIGVFVCWCGSNIGGVVDVPRVAEAAKEMPNVVFATDYKYMCSEPGQELIIKAAKEHNLDRVVVASCSPRLHEQTFRK
AAERAGLNPYMFEMANIREHVSWVHAQEKEKATEKAIELVRRAVFKAARLEPLYKSAIGITKKALVIGGGIAGIQAALDI
ADAGYQVILVEKEPTIGGKMAQLDKTFPTLDCSS*ISTPKMAAAAQHPNIKLYTYAEVTEVSGYIGNFEVTIKQKAKSVD
HNKCTGCGTCWEKCPTKVDSEFDLGLGKRKAIYIPFAQAVPNKPVIDRTTCRQFTKGKCGVCQKVCPTGAVDYDQQDEYI
KEKVGAIIMATGYDLFEWEKVYGEYGYGQYPDVITGLHFERMASASGPTGGKIIRPSDGKEPKTVVFIKCVGSRDDQKGK
SYCSRACCMYTAKHAHQVLEKIPGAQVYIFYMDVRTAGKMYEEFYAKTLEDGAQYIRGRVSKIYPLGDKLIVRGADTLAG
VPVEIEADLVVLATAMVPAKGSEEIAKIVGFSLDKDGFFQEAHPKLGPVETTTGGVFLAGACQGPKDIPDTVAQASAAAA
KVIGLLSKDQLAAEPIVSQVNEALCSGCELCKPICPYKAIDMKKITERVHGKVIERTVATVNTSLCQGCGACTVACRVGA
LNLKGFTNEQLLAEVEAICL
>Mature_660_residues
MKRIGVFVCWCGSNIGGVVDVPRVAEAAKEMPNVVFATDYKYMCSEPGQELIIKAAKEHNLDRVVVASCSPRLHEQTFRK
AAERAGLNPYMFEMANIREHVSWVHAQEKEKATEKAIELVRRAVFKAARLEPLYKSAIGITKKALVIGGGIAGIQAALDI
ADAGYQVILVEKEPTIGGKMAQLDKTFPTLDCSS*ISTPKMAAAAQHPNIKLYTYAEVTEVSGYIGNFEVTIKQKAKSVD
HNKCTGCGTCWEKCPTKVDSEFDLGLGKRKAIYIPFAQAVPNKPVIDRTTCRQFTKGKCGVCQKVCPTGAVDYDQQDEYI
KEKVGAIIMATGYDLFEWEKVYGEYGYGQYPDVITGLHFERMASASGPTGGKIIRPSDGKEPKTVVFIKCVGSRDDQKGK
SYCSRACCMYTAKHAHQVLEKIPGAQVYIFYMDVRTAGKMYEEFYAKTLEDGAQYIRGRVSKIYPLGDKLIVRGADTLAG
VPVEIEADLVVLATAMVPAKGSEEIAKIVGFSLDKDGFFQEAHPKLGPVETTTGGVFLAGACQGPKDIPDTVAQASAAAA
KVIGLLSKDQLAAEPIVSQVNEALCSGCELCKPICPYKAIDMKKITERVHGKVIERTVATVNTSLCQGCGACTVACRVGA
LNLKGFTNEQLLAEVEAICL

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953
- InterPro:   IPR012285 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF00037 Fer4 [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 71476; Mature: 71476

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIGVFVCWCGSNIGGVVDVPRVAEAAKEMPNVVFATDYKYMCSEPGQELIIKAAKEHN
CCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHHCCCCHHHHHHHHHHCC
LDRVVVASCSPRLHEQTFRKAAERAGLNPYMFEMANIREHVSWVHAQEKEKATEKAIELV
CCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRAVFKAARLEPLYKSAIGITKKALVIGGGIAGIQAALDIADAGYQVILVEKEPTIGGKM
HHHHHHHHHCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEEECCCCCCCHH
AQLDKTFPTLDCSSISTPKMAAAAQHPNIKLYTYAEVTEVSGYIGNFEVTIKQKAKSVDH
HHHHCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEEEHHHHCCCCCCEEEEEEHHHCCCCC
NKCTGCGTCWEKCPTKVDSEFDLGLGKRKAIYIPFAQAVPNKPVIDRTTCRQFTKGKCGV
CCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCHHHHHHHCCCCCCH
CQKVCPTGAVDYDQQDEYIKEKVGAIIMATGYDLFEWEKVYGEYGYGQYPDVITGLHFER
HHHHCCCCCCCCCCHHHHHHHHHCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHCCCHHH
MASASGPTGGKIIRPSDGKEPKTVVFIKCVGSRDDQKGKSYCSRACCMYTAKHAHQVLEK
HHCCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IPGAQVYIFYMDVRTAGKMYEEFYAKTLEDGAQYIRGRVSKIYPLGDKLIVRGADTLAGV
CCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCHHHCCC
PVEIEADLVVLATAMVPAKGSEEIAKIVGFSLDKDGFFQEAHPKLGPVETTTGGVFLAGA
CEEECCCEEEEEEHHCCCCCHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEC
CQGPKDIPDTVAQASAAAAKVIGLLSKDQLAAEPIVSQVNEALCSGCELCKPICPYKAID
CCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCC
MKKITERVHGKVIERTVATVNTSLCQGCGACTVACRVGALNLKGFTNEQLLAEVEAICL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEECCEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKRIGVFVCWCGSNIGGVVDVPRVAEAAKEMPNVVFATDYKYMCSEPGQELIIKAAKEHN
CCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHHCCCCHHHHHHHHHHCC
LDRVVVASCSPRLHEQTFRKAAERAGLNPYMFEMANIREHVSWVHAQEKEKATEKAIELV
CCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRAVFKAARLEPLYKSAIGITKKALVIGGGIAGIQAALDIADAGYQVILVEKEPTIGGKM
HHHHHHHHHCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEEECCCCCCCHH
AQLDKTFPTLDCSSISTPKMAAAAQHPNIKLYTYAEVTEVSGYIGNFEVTIKQKAKSVDH
HHHHCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEEEHHHHCCCCCCEEEEEEHHHCCCCC
NKCTGCGTCWEKCPTKVDSEFDLGLGKRKAIYIPFAQAVPNKPVIDRTTCRQFTKGKCGV
CCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCHHHHHHHCCCCCCH
CQKVCPTGAVDYDQQDEYIKEKVGAIIMATGYDLFEWEKVYGEYGYGQYPDVITGLHFER
HHHHCCCCCCCCCCHHHHHHHHHCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHCCCHHH
MASASGPTGGKIIRPSDGKEPKTVVFIKCVGSRDDQKGKSYCSRACCMYTAKHAHQVLEK
HHCCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IPGAQVYIFYMDVRTAGKMYEEFYAKTLEDGAQYIRGRVSKIYPLGDKLIVRGADTLAGV
CCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCHHHCCC
PVEIEADLVVLATAMVPAKGSEEIAKIVGFSLDKDGFFQEAHPKLGPVETTTGGVFLAGA
CEEECCCEEEEEEHHCCCCCHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEC
CQGPKDIPDTVAQASAAAAKVIGLLSKDQLAAEPIVSQVNEALCSGCELCKPICPYKAID
CCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCC
MKKITERVHGKVIERTVATVNTSLCQGCGACTVACRVGALNLKGFTNEQLLAEVEAICL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEECCEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063468; 11930014 [H]