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The map label for this gene is hydC [H]

Identifier: 78044572

GI number: 78044572

Start: 643875

End: 644360

Strand: Direct

Name: hydC [H]

Synonym: CHY_0731

Alternate gene names: 78044572

Gene position: 643875-644360 (Clockwise)

Preceding gene: 78042640

Following gene: 78044500

Centisome position: 26.81

GC content: 46.3

Gene sequence:

>486_bases
TTGGTTTGTGCCTGCGGGAAGGAAGTAGTTGATCCAAAAAAAGAAAAACTAAAAGAACTGCTATCTCAGTATCAAGGGCA
AAAAGGGGCTCTGATTCCGGTTTTACAGGGTGCTCAGGAAATTTATGGCTATCTTCCCAGAGAGGTTATGGAAGAAATAA
GTCGTAGCCTTAAAATTCCTTTTAGCAAGGTTTATGGAGTGGCAACCTTCTATGCTCAGTTTCATCTAAAGCCTCGCGGA
CGCAATGTGATTCGCGCCTGTCTGGGGACTGCCTGTCATGTACGCGGTGGAGCGAAAGTATTTGAGACCCTAAAGAATGA
ACTGGGAATTGGTGATGGGGAGACGACTCCCGATTTACGGTTTACCCTGGAATCGGTAGCCTGCATTGGAGCCTGCGGGT
TAGCTCCGGTAATTATGGTCAACAATGATACTTACGGCCGGCTTACCCCGGATAAGGTAAAAGAAATTCTTGCCAAGTAC
GAATAG

Upstream 100 bases:

>100_bases
TTATCAAAAGGTTATAAAAGGTTATTAAGGTTTATTATTTAATGTTTTTTCCAACATCCAATCTCTAACTTCCAACATCT
AATTAGGGGGTGTATTTTCT

Downstream 100 bases:

>100_bases
GGGGTGCCTTATGAGAAAGGTTTTGATTTGTGCGGGGACTGGTTGCATTTCGTCCGGTTCACCTAAAGTTACCGAAAAGT
TTCGGGAAGAACTATCAAAA

Product: Fe-hydrogenase subunit gamma

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MVCACGKEVVDPKKEKLKELLSQYQGQKGALIPVLQGAQEIYGYLPREVMEEISRSLKIPFSKVYGVATFYAQFHLKPRG
RNVIRACLGTACHVRGGAKVFETLKNELGIGDGETTPDLRFTLESVACIGACGLAPVIMVNNDTYGRLTPDKVKEILAKY
E

Sequences:

>Translated_161_residues
MVCACGKEVVDPKKEKLKELLSQYQGQKGALIPVLQGAQEIYGYLPREVMEEISRSLKIPFSKVYGVATFYAQFHLKPRG
RNVIRACLGTACHVRGGAKVFETLKNELGIGDGETTPDLRFTLESVACIGACGLAPVIMVNNDTYGRLTPDKVKEILAKY
E
>Mature_161_residues
MVCACGKEVVDPKKEKLKELLSQYQGQKGALIPVLQGAQEIYGYLPREVMEEISRSLKIPFSKVYGVATFYAQFHLKPRG
RNVIRACLGTACHVRGGAKVFETLKNELGIGDGETTPDLRFTLESVACIGACGLAPVIMVNNDTYGRLTPDKVKEILAKY
E

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=145, Percent_Identity=38.6206896551724, Blast_Score=111, Evalue=3e-25,
Organism=Escherichia coli, GI1788621, Length=153, Percent_Identity=36.6013071895425, Blast_Score=113, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17561328, Length=147, Percent_Identity=43.5374149659864, Blast_Score=126, Evalue=5e-30,
Organism=Drosophila melanogaster, GI18859877, Length=152, Percent_Identity=42.7631578947368, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21355353, Length=147, Percent_Identity=39.4557823129252, Blast_Score=117, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17710; Mature: 17710

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVCACGKEVVDPKKEKLKELLSQYQGQKGALIPVLQGAQEIYGYLPREVMEEISRSLKIP
CCCCCCCHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
FSKVYGVATFYAQFHLKPRGRNVIRACLGTACHVRGGAKVFETLKNELGIGDGETTPDLR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHH
FTLESVACIGACGLAPVIMVNNDTYGRLTPDKVKEILAKYE
HHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MVCACGKEVVDPKKEKLKELLSQYQGQKGALIPVLQGAQEIYGYLPREVMEEISRSLKIP
CCCCCCCHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
FSKVYGVATFYAQFHLKPRGRNVIRACLGTACHVRGGAKVFETLKNELGIGDGETTPDLR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHH
FTLESVACIGACGLAPVIMVNNDTYGRLTPDKVKEILAKYE
HHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA