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The map label for this gene is secA

Identifier: 78044472

GI number: 78044472

Start: 134394

End: 137018

Strand: Direct

Name: secA

Synonym: CHY_0162

Alternate gene names: 78044472

Gene position: 134394-137018 (Clockwise)

Preceding gene: 78042770

Following gene: 78044242

Centisome position: 5.6

GC content: 49.14

Gene sequence:

>2625_bases
ATGCTGAAGTTTTTAAAGAATTTACTGGACGATAATGCCCGGGAGATTAAGAGGCTTACGGCCCGGGTGGAAGAGATAAA
TAGTTTAGAGCCCCAAATGCAAAAGCTTTCCGACGAAGAGCTGAGGGCTAAAACCGGGGAGTTTAAAGAACGTATAGCCC
GCGGTGAAAGTTTGGACGAACTTTTACCGGAAGCTTTTGCGGTGGTCAGGGAAGCTTCCCGCCGGGTTCTGGGGATGCGG
CATTTTGATGTGCAATTGATGGGGGGCATTGTACTTCACGAAGGTAAAATTGCCGAGATGAAAACCGGGGAAGGTAAAAC
TTTAGTCGCTACCCTGCCGGCATATCTCAATGCCCTTACCGGTCGCGGTGTGCATATCGTAACGGTAAACGACTACCTGG
CCCGGCGTGATGCGGAATGGATGGGAAAAATTTACAAGTTTTTGGGTCTTTCGGTGGGTCTGGTGGTCCACGGCATGGAT
TATGCCGAAAAAAAAGCGGCCTATCTGGCGGATATTACTTACGGTACCAACAACGAGTTTGGATTTGATTATCTCAGGGA
TAACATGGCTATCCATCCGGACCAGGTGGTGCAGCGGGAGCTTTATTATGCTATTATTGACGAAGTGGACAGCATTTTAA
TCGATGAGGCCAGAACCCCGCTGATTATTTCCGGGGAAGCGGAAAAGTCCACCGACCTCTACTATACCTTTGCCAAAATT
GTAAAGCAATTAGTGCCCGGGGAAGATTACACCGTGGACGAGAAAGCGCATGCGGTTATGCCTACCGAAGCGGGGATTCA
TAAAGTTGAAAAAATGCTTGGTATTCAAAACCTGTATGCTGATGAACACATGGAGTTAACCCACCATTTAAATGCGGCTT
TAAAAGCGCAAGCTTTAATGAAGCGGGACCGGGATTATGTAGTCAAAGACGGTCAGGTAATTATCGTGGACGAATTTACC
GGACGCCTTATGTTCGGCCGCCGGTATTCCGATGGATTGCACCAGGCCATAGAAGCCAAGGAAGGGGTCAAGATTGAGCA
GGAGACCCAGACCTTAGCAACCATTACTTTCCAGAATTATTTCCGGATGTACGAAAAATTAGCCGGGATGACCGGTACGG
CGGAAACGGAAGAAAACGAGTTTCGCAAGATTTATAACCTGTCGGTAGTGGTAATTCCAACCCATAAGCCGATGATTCGT
AAGGATTTGCCCGATGTAATTTTTAAAACCGAAAAGGCCAAGTTTAAGGCAATTGTGGAGGAAGTGGCGCGGCGGCACCA
GACCGGCCAGCCGATCTTGATTGGTACCATTTCCATTGAAAAATCCGAAATGTTAAGCGAAATGCTGAAAAAACGGGGAA
TTCCCCATCAAGTCTTAAACGCCAAATACCACGAAAAAGAAGCGGAAATTGTAGCCCAGGCGGGAAGGCTTGGGGCCGTG
ACCATTGCTACCAACATGGCCGGTCGGGGTACCGATATTTTACTGGGAGGTAACCCGGAATTTTTGGCCCTTCAGGAATT
AAGAAAAATGGGAAAAACTCCGGAAGATGACCCGGAACTGTACCGGGAACTTTTGGCCAAATACAAAAAAATAACCGATG
AAGAGCACAAAAAAGTGGTGGAGTTAGGGGGTCTCCACATTATTGGTACCGAACGGCACGAGTCCCGCCGGATTGATAAC
CAGCTCCGGGGACGGGCCGGGCGGCAGGGAGACCCGGGTTCGTCGCAATTTTTCATTTCCCTTGAAGATGACCTGATGCG
CCTTTTTGGCTCCGATAACATTGCCGGGCTTATGGATCGCCTGGGTTTGGATGAAGATACCCCAATTGAACATCCGCTTA
TTACCAGGTCCATTGAGACGGCGCAAAAACGGGTGGAAAACCGGAACTTTGAAATTAGAAAACACGTTTTAGAATACGAT
AACGTTATGAACCAGCAGCGGGAGCTTATTTACAGCCAGCGCCGGCGGGTGCTTTTTGGGGAAGATGTCCTGACCTTTGT
CCACCAGATGATAGAAGCGGTGGTGGAGCGGGCAGTCGATACTTACTGCCCCGATGGCGTTCACCCGGAAGAATGGGATT
TAAAGGGATTATTGGAGTACGCTCATAATGTCTTTTTGCCCAACCACCAGTTAACTCCCGAAGATTTAGCCGATACCGGC
AAGAAAGCTTTGGTGGAGTTTTTGGTGGAAAAAGCCAAAGAATACTACAAAAAGCGGGAAGAAGAGCTTGGCGGTGAGCA
GCTCCGGGAGTTAGAACGGTACGTTATCCTGCGGGTAGTGGATGAGAAGTGGATGGACCACCTGGATGCCATGGACCAGC
TGCGGGAAGGTATAGGGCTTAGAGCTTACGGGCAAAAAGACCCGCTGGTGGAATACAAAATCGAAAGCGTTGAAATGTTC
AACAACATGATTGCTGCCATTCAGGAAGATGTGGTGCGTTATTTAATGCGGCTTTCCGTGGTCCGGCAGCCGGAAACCAG
GAGGGTCCGGCGGGTGGTGGAAAACCGCTATCAGGAAGAAGGACCGAAAAAACCCTACCGCCGGGAGCAAAAAATTGGCC
GCAATGATCCCTGTCCCTGCGGTAGCGGTAAGAAATACAAGAAGTGCTGTGGCAGAAACGGGTAA

Upstream 100 bases:

>100_bases
AAAGAAAAGATTTGCGGTAGATAGTTGAAAGTGGTAAAATGAAAAGAAGAGCTATCAGGGAACCGTAACGGTTCCTTTAT
TTGTGCAAAGAGGTGAAAAT

Downstream 100 bases:

>100_bases
AGGAAGTGGTTAGCTATGTTAATTGAGCTGAAAAGAAGTTTGGCGGAGATTTCCCCCAAGATTGAGGAAATGAGGGTTTC
TCTTTGACATTCCCGGGAAA

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 874; Mature: 874

Protein sequence:

>874_residues
MLKFLKNLLDDNAREIKRLTARVEEINSLEPQMQKLSDEELRAKTGEFKERIARGESLDELLPEAFAVVREASRRVLGMR
HFDVQLMGGIVLHEGKIAEMKTGEGKTLVATLPAYLNALTGRGVHIVTVNDYLARRDAEWMGKIYKFLGLSVGLVVHGMD
YAEKKAAYLADITYGTNNEFGFDYLRDNMAIHPDQVVQRELYYAIIDEVDSILIDEARTPLIISGEAEKSTDLYYTFAKI
VKQLVPGEDYTVDEKAHAVMPTEAGIHKVEKMLGIQNLYADEHMELTHHLNAALKAQALMKRDRDYVVKDGQVIIVDEFT
GRLMFGRRYSDGLHQAIEAKEGVKIEQETQTLATITFQNYFRMYEKLAGMTGTAETEENEFRKIYNLSVVVIPTHKPMIR
KDLPDVIFKTEKAKFKAIVEEVARRHQTGQPILIGTISIEKSEMLSEMLKKRGIPHQVLNAKYHEKEAEIVAQAGRLGAV
TIATNMAGRGTDILLGGNPEFLALQELRKMGKTPEDDPELYRELLAKYKKITDEEHKKVVELGGLHIIGTERHESRRIDN
QLRGRAGRQGDPGSSQFFISLEDDLMRLFGSDNIAGLMDRLGLDEDTPIEHPLITRSIETAQKRVENRNFEIRKHVLEYD
NVMNQQRELIYSQRRRVLFGEDVLTFVHQMIEAVVERAVDTYCPDGVHPEEWDLKGLLEYAHNVFLPNHQLTPEDLADTG
KKALVEFLVEKAKEYYKKREEELGGEQLRELERYVILRVVDEKWMDHLDAMDQLREGIGLRAYGQKDPLVEYKIESVEMF
NNMIAAIQEDVVRYLMRLSVVRQPETRRVRRVVENRYQEEGPKKPYRREQKIGRNDPCPCGSGKKYKKCCGRNG

Sequences:

>Translated_874_residues
MLKFLKNLLDDNAREIKRLTARVEEINSLEPQMQKLSDEELRAKTGEFKERIARGESLDELLPEAFAVVREASRRVLGMR
HFDVQLMGGIVLHEGKIAEMKTGEGKTLVATLPAYLNALTGRGVHIVTVNDYLARRDAEWMGKIYKFLGLSVGLVVHGMD
YAEKKAAYLADITYGTNNEFGFDYLRDNMAIHPDQVVQRELYYAIIDEVDSILIDEARTPLIISGEAEKSTDLYYTFAKI
VKQLVPGEDYTVDEKAHAVMPTEAGIHKVEKMLGIQNLYADEHMELTHHLNAALKAQALMKRDRDYVVKDGQVIIVDEFT
GRLMFGRRYSDGLHQAIEAKEGVKIEQETQTLATITFQNYFRMYEKLAGMTGTAETEENEFRKIYNLSVVVIPTHKPMIR
KDLPDVIFKTEKAKFKAIVEEVARRHQTGQPILIGTISIEKSEMLSEMLKKRGIPHQVLNAKYHEKEAEIVAQAGRLGAV
TIATNMAGRGTDILLGGNPEFLALQELRKMGKTPEDDPELYRELLAKYKKITDEEHKKVVELGGLHIIGTERHESRRIDN
QLRGRAGRQGDPGSSQFFISLEDDLMRLFGSDNIAGLMDRLGLDEDTPIEHPLITRSIETAQKRVENRNFEIRKHVLEYD
NVMNQQRELIYSQRRRVLFGEDVLTFVHQMIEAVVERAVDTYCPDGVHPEEWDLKGLLEYAHNVFLPNHQLTPEDLADTG
KKALVEFLVEKAKEYYKKREEELGGEQLRELERYVILRVVDEKWMDHLDAMDQLREGIGLRAYGQKDPLVEYKIESVEMF
NNMIAAIQEDVVRYLMRLSVVRQPETRRVRRVVENRYQEEGPKKPYRREQKIGRNDPCPCGSGKKYKKCCGRNG
>Mature_874_residues
MLKFLKNLLDDNAREIKRLTARVEEINSLEPQMQKLSDEELRAKTGEFKERIARGESLDELLPEAFAVVREASRRVLGMR
HFDVQLMGGIVLHEGKIAEMKTGEGKTLVATLPAYLNALTGRGVHIVTVNDYLARRDAEWMGKIYKFLGLSVGLVVHGMD
YAEKKAAYLADITYGTNNEFGFDYLRDNMAIHPDQVVQRELYYAIIDEVDSILIDEARTPLIISGEAEKSTDLYYTFAKI
VKQLVPGEDYTVDEKAHAVMPTEAGIHKVEKMLGIQNLYADEHMELTHHLNAALKAQALMKRDRDYVVKDGQVIIVDEFT
GRLMFGRRYSDGLHQAIEAKEGVKIEQETQTLATITFQNYFRMYEKLAGMTGTAETEENEFRKIYNLSVVVIPTHKPMIR
KDLPDVIFKTEKAKFKAIVEEVARRHQTGQPILIGTISIEKSEMLSEMLKKRGIPHQVLNAKYHEKEAEIVAQAGRLGAV
TIATNMAGRGTDILLGGNPEFLALQELRKMGKTPEDDPELYRELLAKYKKITDEEHKKVVELGGLHIIGTERHESRRIDN
QLRGRAGRQGDPGSSQFFISLEDDLMRLFGSDNIAGLMDRLGLDEDTPIEHPLITRSIETAQKRVENRNFEIRKHVLEYD
NVMNQQRELIYSQRRRVLFGEDVLTFVHQMIEAVVERAVDTYCPDGVHPEEWDLKGLLEYAHNVFLPNHQLTPEDLADTG
KKALVEFLVEKAKEYYKKREEELGGEQLRELERYVILRVVDEKWMDHLDAMDQLREGIGLRAYGQKDPLVEYKIESVEMF
NNMIAAIQEDVVRYLMRLSVVRQPETRRVRRVVENRYQEEGPKKPYRREQKIGRNDPCPCGSGKKYKKCCGRNG

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=912, Percent_Identity=53.0701754385965, Blast_Score=926, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_CARHZ (Q3AFQ0)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359034.1
- HSSP:   P10408
- ProteinModelPortal:   Q3AFQ0
- SMR:   Q3AFQ0
- STRING:   Q3AFQ0
- GeneID:   3727591
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0162
- NMPDR:   fig|246194.3.peg.944
- TIGR:   CHY_0162
- eggNOG:   COG0653
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- ProtClustDB:   PRK12904
- BioCyc:   CHYD246194:CHY_0162-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 100253; Mature: 100253

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFLKNLLDDNAREIKRLTARVEEINSLEPQMQKLSDEELRAKTGEFKERIARGESLDE
CHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCHHH
LLPEAFAVVREASRRVLGMRHFDVQLMGGIVLHEGKIAEMKTGEGKTLVATLPAYLNALT
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEECCCEEEEECCCCCEEEEHHHHHHHHHC
GRGVHIVTVNDYLARRDAEWMGKIYKFLGLSVGLVVHGMDYAEKKAAYLADITYGTNNEF
CCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEECCCCCC
GFDYLRDNMAIHPDQVVQRELYYAIIDEVDSILIDEARTPLIISGEAEKSTDLYYTFAKI
CHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH
VKQLVPGEDYTVDEKAHAVMPTEAGIHKVEKMLGIQNLYADEHMELTHHLNAALKAQALM
HHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRDRDYVVKDGQVIIVDEFTGRLMFGRRYSDGLHQAIEAKEGVKIEQETQTLATITFQNY
HCCCCEEEECCCEEEEECCCCCEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FRMYEKLAGMTGTAETEENEFRKIYNLSVVVIPTHKPMIRKDLPDVIFKTEKAKFKAIVE
HHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHH
EVARRHQTGQPILIGTISIEKSEMLSEMLKKRGIPHQVLNAKYHEKEAEIVAQAGRLGAV
HHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCCCEE
TIATNMAGRGTDILLGGNPEFLALQELRKMGKTPEDDPELYRELLAKYKKITDEEHKKVV
EEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
ELGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSQFFISLEDDLMRLFGSDNIAGLMDR
HHCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCHHHHHHH
LGLDEDTPIEHPLITRSIETAQKRVENRNFEIRKHVLEYDNVMNQQRELIYSQRRRVLFG
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
EDVLTFVHQMIEAVVERAVDTYCPDGVHPEEWDLKGLLEYAHNVFLPNHQLTPEDLADTG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
KKALVEFLVEKAKEYYKKREEELGGEQLRELERYVILRVVDEKWMDHLDAMDQLREGIGL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
RAYGQKDPLVEYKIESVEMFNNMIAAIQEDVVRYLMRLSVVRQPETRRVRRVVENRYQEE
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GPKKPYRREQKIGRNDPCPCGSGKKYKKCCGRNG
CCCCCHHHHHHCCCCCCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MLKFLKNLLDDNAREIKRLTARVEEINSLEPQMQKLSDEELRAKTGEFKERIARGESLDE
CHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCHHH
LLPEAFAVVREASRRVLGMRHFDVQLMGGIVLHEGKIAEMKTGEGKTLVATLPAYLNALT
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEECCCEEEEECCCCCEEEEHHHHHHHHHC
GRGVHIVTVNDYLARRDAEWMGKIYKFLGLSVGLVVHGMDYAEKKAAYLADITYGTNNEF
CCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEECCCCCC
GFDYLRDNMAIHPDQVVQRELYYAIIDEVDSILIDEARTPLIISGEAEKSTDLYYTFAKI
CHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH
VKQLVPGEDYTVDEKAHAVMPTEAGIHKVEKMLGIQNLYADEHMELTHHLNAALKAQALM
HHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRDRDYVVKDGQVIIVDEFTGRLMFGRRYSDGLHQAIEAKEGVKIEQETQTLATITFQNY
HCCCCEEEECCCEEEEECCCCCEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FRMYEKLAGMTGTAETEENEFRKIYNLSVVVIPTHKPMIRKDLPDVIFKTEKAKFKAIVE
HHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHH
EVARRHQTGQPILIGTISIEKSEMLSEMLKKRGIPHQVLNAKYHEKEAEIVAQAGRLGAV
HHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCCCEE
TIATNMAGRGTDILLGGNPEFLALQELRKMGKTPEDDPELYRELLAKYKKITDEEHKKVV
EEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
ELGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSQFFISLEDDLMRLFGSDNIAGLMDR
HHCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCHHHHHHH
LGLDEDTPIEHPLITRSIETAQKRVENRNFEIRKHVLEYDNVMNQQRELIYSQRRRVLFG
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
EDVLTFVHQMIEAVVERAVDTYCPDGVHPEEWDLKGLLEYAHNVFLPNHQLTPEDLADTG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
KKALVEFLVEKAKEYYKKREEELGGEQLRELERYVILRVVDEKWMDHLDAMDQLREGIGL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
RAYGQKDPLVEYKIESVEMFNNMIAAIQEDVVRYLMRLSVVRQPETRRVRRVVENRYQEE
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GPKKPYRREQKIGRNDPCPCGSGKKYKKCCGRNG
CCCCCHHHHHHCCCCCCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA