Click here to switch to the map view.

The map label for this gene is fchA1 [H]

Identifier: 78044406

GI number: 78044406

Start: 609989

End: 610612

Strand: Direct

Name: fchA1 [H]

Synonym: CHY_0696

Alternate gene names: 78044406

Gene position: 609989-610612 (Clockwise)

Preceding gene: 78043831

Following gene: 78045001

Centisome position: 25.4

GC content: 43.59

Gene sequence:

>624_bases
ATGCTAACGGACTTGTCCATACGTGGGTTTATAATGGAATTAGCTTCTTCTTCTCCAGCACCCGGTGGAGGCAGTGTTTC
AGCCTTAGCCGGAGCTAACGGTGCTGCCCTTTTAAATATGGTGTTAAATTTAACCCTTGGCCGGGAAAAATTTGCCGACG
TTGAAGCGGAACTTGCTCCTTTAAAGGATAAAACCGAAGCTTTATACGAACGTTTGGTTAATTTAATTGATATCGATACC
GAAGTTTTTAACGAAGTAATGGCGGCGTTTAAGCTTCCCAAAGATACCGAAGAGCAGAAAAAAGAGCGTTCGGTGAAAAT
TCAAGAAGCCTATAAAAAAGCGGCCGACGTTCCCTTGGAAGTAGCCGAAAGGTGCCTGGAAGTTTTACGCCTGTGTCCAA
TTATTGCTGAAAAAGGAAATCCCAATGCTCTTTCCGATGCCGGTGTTGCCGCGCAAATGGCTTATGCGGGCCTTGAAGGG
GCAGTTATGAATGTGAAAATTAACCTTAGTTCCATCAAAGATGAGGAGTATGTAGCCGCTGCCCGAGAAAAAGTAGCAGC
TTTCTTAAAAGAGGGTGCCGAGATTAAAGACAGGGTAGCCAATTATGTAAATGAAAAATTATAA

Upstream 100 bases:

>100_bases
ACCGCGACCAAATTCGGGAAAACCACATACCTGACTTACTGTAAGAAAACCGGGCAGGGTTTACCCCTGCCCTTCCCCTA
ATTAAACAGGAGGTGTAATA

Downstream 100 bases:

>100_bases
ACAAAATTATAAAGCATAAAGGAAATCAATTCTACAAAATGCGACAAAAAAATATTTTTTCTGAAAATTAAAGAAGGAAT
TTTAAAATCCGTGTCGAATA

Product: methenyltetrahydrofolate cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MLTDLSIRGFIMELASSSPAPGGGSVSALAGANGAALLNMVLNLTLGREKFADVEAELAPLKDKTEALYERLVNLIDIDT
EVFNEVMAAFKLPKDTEEQKKERSVKIQEAYKKAADVPLEVAERCLEVLRLCPIIAEKGNPNALSDAGVAAQMAYAGLEG
AVMNVKINLSSIKDEEYVAAAREKVAAFLKEGAEIKDRVANYVNEKL

Sequences:

>Translated_207_residues
MLTDLSIRGFIMELASSSPAPGGGSVSALAGANGAALLNMVLNLTLGREKFADVEAELAPLKDKTEALYERLVNLIDIDT
EVFNEVMAAFKLPKDTEEQKKERSVKIQEAYKKAADVPLEVAERCLEVLRLCPIIAEKGNPNALSDAGVAAQMAYAGLEG
AVMNVKINLSSIKDEEYVAAAREKVAAFLKEGAEIKDRVANYVNEKL
>Mature_207_residues
MLTDLSIRGFIMELASSSPAPGGGSVSALAGANGAALLNMVLNLTLGREKFADVEAELAPLKDKTEALYERLVNLIDIDT
EVFNEVMAAFKLPKDTEEQKKERSVKIQEAYKKAADVPLEVAERCLEVLRLCPIIAEKGNPNALSDAGVAAQMAYAGLEG
AVMNVKINLSSIKDEEYVAAAREKVAAFLKEGAEIKDRVANYVNEKL

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=186, Percent_Identity=37.6344086021505, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI11140815, Length=186, Percent_Identity=37.6344086021505, Blast_Score=87, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 22300; Mature: 22300

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDLSIRGFIMELASSSPAPGGGSVSALAGANGAALLNMVLNLTLGREKFADVEAELAP
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHC
LKDKTEALYERLVNLIDIDTEVFNEVMAAFKLPKDTEEQKKERSVKIQEAYKKAADVPLE
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCHH
VAERCLEVLRLCPIIAEKGNPNALSDAGVAAQMAYAGLEGAVMNVKINLSSIKDEEYVAA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEHHHCCCHHHHHH
AREKVAAFLKEGAEIKDRVANYVNEKL
HHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTDLSIRGFIMELASSSPAPGGGSVSALAGANGAALLNMVLNLTLGREKFADVEAELAP
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHC
LKDKTEALYERLVNLIDIDTEVFNEVMAAFKLPKDTEEQKKERSVKIQEAYKKAADVPLE
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCHH
VAERCLEVLRLCPIIAEKGNPNALSDAGVAAQMAYAGLEGAVMNVKINLSSIKDEEYVAA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEHHHCCCHHHHHH
AREKVAAFLKEGAEIKDRVANYVNEKL
HHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]