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The map label for this gene is uxaA [H]

Identifier: 78044218

GI number: 78044218

Start: 1147120

End: 1148280

Strand: Direct

Name: uxaA [H]

Synonym: CHY_1290

Alternate gene names: 78044218

Gene position: 1147120-1148280 (Clockwise)

Preceding gene: 78044634

Following gene: 78044398

Centisome position: 47.77

GC content: 38.16

Gene sequence:

>1161_bases
ATGAAATTTTGGGGATATCAAAGGCCTGATGGAAGGATAGGGATAAGAAATCATATTTTGCTTTTACCGACCTGTGCATG
TTCAAGTGAAACATGTAGGTTTGCTGCTTTACAGGTGACAGGGGCAGTATCAATAATAAATCAAAATGGATGTGCTCAGG
TAAAAGGTGACCTTGAAATTACAGAAAAAGTTTTAGCAGGCTTGGCGGCTAATCCAAATGTTTTTGGAACTGTTTTAGTT
GGTCTAGGGTGTGAAAATGCCCAGCCCGATAAGATGGAACAACTTATAAAAGCTAAAACTAATAAACCGCTAAAAAAAGT
TATTATTCAAGAAGTTGGAGGTACTTTAGCTGCTATTAAACAAATTGTGGAATATGCTAGAGAAATGGTGGAAGAAGCAT
CAATGCTTCAGAAAGAAGAGTTTGATATCTCAAATTTGATTGTAGGGACAGAATGTGGAGGATCGGATCCAACATCAGGC
TTGGTTGCCAATCCTGTTGTGGGTAACCTAAGTGATAGATTAGTTGATATGGGGGCTACGGTTATCCTTAGTGAGACAAC
GGAGTTTATTGGGGCGGAGCATATTTTAGCAGCACAGGCGGAAACACCGGAAGTAGCTAAAAGAATTTACGCGATTATTA
ATAAATATGAAGAACATTTAAAAAGTGTAGGTGAAAGCTTAAGAGAAGGCAACCCGTCTCCAGGAAATAAAGCTGGAGGT
ATAACAACCTTAGAAGAAAAATCATTGGGATGCATCCATAAAGGGGGACACAGACCCATAGTTGAAGTAGTAGATTATGC
TGAAGAAGTAACTAAAAAAGGTTTAGTTATCATGGATACACCAGGATATGATATAGCTTCCGTAACTGGCATGGTAGCTG
GAGGAGCCCAGATAGTTGTTTTTACAACTGGGAGGGGTACTCCCACGGGTAACCCGATTGCGCCAGTAATTAAGATAACG
GGAAATAGAGCAACATATGAAAAGATGAAAGAAAATATTGATTTTGATGCTAGTTCGTTACTTAGAGGTGAAAAAAGTTT
AGAACAGTTAGGGGAAGAACTTTTTTATGAAGTATTAAAAGTTGCAAATGGGAAAAAGACTAAAGCAGAATCTTTTGGTT
TTAGTGAGATAGCAATAAGCAGACTTTGCAATTATGTATAG

Upstream 100 bases:

>100_bases
CTACAAGAGATATTCAAATTGGGGAGCATGTGCATAGCCATAATCTTTCCAGCTTACGGGAAGATTTAATAAAGTAATCG
TTCAGAAGGTGAAATATTAC

Downstream 100 bases:

>100_bases
TTGCATTTTTATGACAAAAAGACTCACGGTAAAAAATCAAGGACCAAGAAATGGAAATTAGAAAAGTAGGGGCTAAAAAA
GGCAATAATAACCCTCTCCA

Product: UxaA family hydrolase

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKFWGYQRPDGRIGIRNHILLLPTCACSSETCRFAALQVTGAVSIINQNGCAQVKGDLEITEKVLAGLAANPNVFGTVLV
GLGCENAQPDKMEQLIKAKTNKPLKKVIIQEVGGTLAAIKQIVEYAREMVEEASMLQKEEFDISNLIVGTECGGSDPTSG
LVANPVVGNLSDRLVDMGATVILSETTEFIGAEHILAAQAETPEVAKRIYAIINKYEEHLKSVGESLREGNPSPGNKAGG
ITTLEEKSLGCIHKGGHRPIVEVVDYAEEVTKKGLVIMDTPGYDIASVTGMVAGGAQIVVFTTGRGTPTGNPIAPVIKIT
GNRATYEKMKENIDFDASSLLRGEKSLEQLGEELFYEVLKVANGKKTKAESFGFSEIAISRLCNYV

Sequences:

>Translated_386_residues
MKFWGYQRPDGRIGIRNHILLLPTCACSSETCRFAALQVTGAVSIINQNGCAQVKGDLEITEKVLAGLAANPNVFGTVLV
GLGCENAQPDKMEQLIKAKTNKPLKKVIIQEVGGTLAAIKQIVEYAREMVEEASMLQKEEFDISNLIVGTECGGSDPTSG
LVANPVVGNLSDRLVDMGATVILSETTEFIGAEHILAAQAETPEVAKRIYAIINKYEEHLKSVGESLREGNPSPGNKAGG
ITTLEEKSLGCIHKGGHRPIVEVVDYAEEVTKKGLVIMDTPGYDIASVTGMVAGGAQIVVFTTGRGTPTGNPIAPVIKIT
GNRATYEKMKENIDFDASSLLRGEKSLEQLGEELFYEVLKVANGKKTKAESFGFSEIAISRLCNYV
>Mature_386_residues
MKFWGYQRPDGRIGIRNHILLLPTCACSSETCRFAALQVTGAVSIINQNGCAQVKGDLEITEKVLAGLAANPNVFGTVLV
GLGCENAQPDKMEQLIKAKTNKPLKKVIIQEVGGTLAAIKQIVEYAREMVEEASMLQKEEFDISNLIVGTECGGSDPTSG
LVANPVVGNLSDRLVDMGATVILSETTEFIGAEHILAAQAETPEVAKRIYAIINKYEEHLKSVGESLREGNPSPGNKAGG
ITTLEEKSLGCIHKGGHRPIVEVVDYAEEVTKKGLVIMDTPGYDIASVTGMVAGGAQIVVFTTGRGTPTGNPIAPVIKIT
GNRATYEKMKENIDFDASSLLRGEKSLEQLGEELFYEVLKVANGKKTKAESFGFSEIAISRLCNYV

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=386, Percent_Identity=33.6787564766839, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789516, Length=392, Percent_Identity=34.1836734693878, Blast_Score=207, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 41359; Mature: 41359

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFWGYQRPDGRIGIRNHILLLPTCACSSETCRFAALQVTGAVSIINQNGCAQVKGDLEI
CCCCCCCCCCCCEECCCCEEEEEECCCCCCCCEEEEEEEEEEEEEEECCCCEEECCCHHH
TEKVLAGLAANPNVFGTVLVGLGCENAQPDKMEQLIKAKTNKPLKKVIIQEVGGTLAAIK
HHHHHHHHCCCCCHHEEHEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHH
QIVEYAREMVEEASMLQKEEFDISNLIVGTECGGSDPTSGLVANPVVGNLSDRLVDMGAT
HHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCE
VILSETTEFIGAEHILAAQAETPEVAKRIYAIINKYEEHLKSVGESLREGNPSPGNKAGG
EEEECHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ITTLEEKSLGCIHKGGHRPIVEVVDYAEEVTKKGLVIMDTPGYDIASVTGMVAGGAQIVV
CEEEHHCCCCCHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCCEEEE
FTTGRGTPTGNPIAPVIKITGNRATYEKMKENIDFDASSLLRGEKSLEQLGEELFYEVLK
EECCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VANGKKTKAESFGFSEIAISRLCNYV
HCCCCCCCHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKFWGYQRPDGRIGIRNHILLLPTCACSSETCRFAALQVTGAVSIINQNGCAQVKGDLEI
CCCCCCCCCCCCEECCCCEEEEEECCCCCCCCEEEEEEEEEEEEEEECCCCEEECCCHHH
TEKVLAGLAANPNVFGTVLVGLGCENAQPDKMEQLIKAKTNKPLKKVIIQEVGGTLAAIK
HHHHHHHHCCCCCHHEEHEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHH
QIVEYAREMVEEASMLQKEEFDISNLIVGTECGGSDPTSGLVANPVVGNLSDRLVDMGAT
HHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCE
VILSETTEFIGAEHILAAQAETPEVAKRIYAIINKYEEHLKSVGESLREGNPSPGNKAGG
EEEECHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ITTLEEKSLGCIHKGGHRPIVEVVDYAEEVTKKGLVIMDTPGYDIASVTGMVAGGAQIVV
CEEEHHCCCCCHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCCEEEE
FTTGRGTPTGNPIAPVIKITGNRATYEKMKENIDFDASSLLRGEKSLEQLGEELFYEVLK
EECCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VANGKKTKAESFGFSEIAISRLCNYV
HCCCCCCCHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]