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The map label for this gene is lytT [H]

Identifier: 78044195

GI number: 78044195

Start: 571061

End: 571816

Strand: Direct

Name: lytT [H]

Synonym: CHY_0658

Alternate gene names: 78044195

Gene position: 571061-571816 (Clockwise)

Preceding gene: 78043390

Following gene: 78044614

Centisome position: 23.78

GC content: 44.58

Gene sequence:

>756_bases
ATGAAAATTAGGACGCTCATTGTGGATGATGAGTATCCTGCCCGGCAGGAACTGCGTTTTTTGTTAGCGGAGATTCCGGA
AATTGAAGTGGTGGGGGAGGCGGCAACGGCCAGCGAAGCCCTTGCGTTAATCCGGGCGGTGGATTATTCTTTGTTGTTTT
TGGATATTGAAATGCCGGGACTTTCCGGGCTTGAGCTGGCCAAGGAAATCAATGCCCTGCCCCATCCGCCGTATGTGGTT
TTTGTTACCGCTTATGACGAGTATGCTTTAAAAGCGTTTGAAGTTAATGCGGTAGATTATTTACTAAAACCTATTGAGCC
CAAAAGGCTAAAAAAAGCCGTAGAAAAGGTAAAGAAGCTAATCCAGGAAAACGGCTTACCAAAAGGGGAGGAAGTTTTTA
GCGCGTACCGCACAACGGGAAGACTTGACCGCATACCGGCCGAAAAAGGCGGGAAAACGGTTTTGGTTGGGGAGCAGGAG
ATTATTTATGCCTATACCGAACAGGATTATGTTTACCTGAAAACCTATCAGGATAAATACTTTACCCGTTTTACCCTGAA
AGAATTAGAAGGACGGTTAAATCCCACGGTGTTTTTCCGCTGTCACCGCTGTTTTATTGTCAATCTGCAAAAGGTAAAAG
AGATAATACCCTTTTTTAACGGCACCTATACTTTAGTGGTGGATGATAAAGAGAAAAGCGAAGTTCCGGTAAGCAGAGCC
CAGGCGAAAAAATTAAGAAAAATCCTCGGACTTTAA

Upstream 100 bases:

>100_bases
CGGGAGGCGGGCCTTAAAATAGAGTCGAAGTTAGGGGTGGGGACTACCGTGAGTTTTTCCATTCCGGCGTTAAAAGTTGA
AGAAGAAGGGGAGAGGGAAA

Downstream 100 bases:

>100_bases
ACCGTTAAAAGCAGAAAAAATGCTTTTTAACGTTTTTTTTTTACCTTTCACAATCAAAAACTGGATTAATAACCGTTGCC
AAATTATTATATAAAAAAAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKIRTLIVDDEYPARQELRFLLAEIPEIEVVGEAATASEALALIRAVDYSLLFLDIEMPGLSGLELAKEINALPHPPYVV
FVTAYDEYALKAFEVNAVDYLLKPIEPKRLKKAVEKVKKLIQENGLPKGEEVFSAYRTTGRLDRIPAEKGGKTVLVGEQE
IIYAYTEQDYVYLKTYQDKYFTRFTLKELEGRLNPTVFFRCHRCFIVNLQKVKEIIPFFNGTYTLVVDDKEKSEVPVSRA
QAKKLRKILGL

Sequences:

>Translated_251_residues
MKIRTLIVDDEYPARQELRFLLAEIPEIEVVGEAATASEALALIRAVDYSLLFLDIEMPGLSGLELAKEINALPHPPYVV
FVTAYDEYALKAFEVNAVDYLLKPIEPKRLKKAVEKVKKLIQENGLPKGEEVFSAYRTTGRLDRIPAEKGGKTVLVGEQE
IIYAYTEQDYVYLKTYQDKYFTRFTLKELEGRLNPTVFFRCHRCFIVNLQKVKEIIPFFNGTYTLVVDDKEKSEVPVSRA
QAKKLRKILGL
>Mature_251_residues
MKIRTLIVDDEYPARQELRFLLAEIPEIEVVGEAATASEALALIRAVDYSLLFLDIEMPGLSGLELAKEINALPHPPYVV
FVTAYDEYALKAFEVNAVDYLLKPIEPKRLKKAVEKVKKLIQENGLPKGEEVFSAYRTTGRLDRIPAEKGGKTVLVGEQE
IIYAYTEQDYVYLKTYQDKYFTRFTLKELEGRLNPTVFFRCHRCFIVNLQKVKEIIPFFNGTYTLVVDDKEKSEVPVSRA
QAKKLRKILGL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=249, Percent_Identity=34.5381526104418, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI87082052, Length=253, Percent_Identity=37.5494071146245, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1788222, Length=117, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28743; Mature: 28743

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRTLIVDDEYPARQELRFLLAEIPEIEVVGEAATASEALALIRAVDYSLLFLDIEMPG
CEEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCEEEEEEEEECCC
LSGLELAKEINALPHPPYVVFVTAYDEYALKAFEVNAVDYLLKPIEPKRLKKAVEKVKKL
CCHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHH
IQENGLPKGEEVFSAYRTTGRLDRIPAEKGGKTVLVGEQEIIYAYTEQDYVYLKTYQDKY
HHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCEEEEEEECCCEEEEEEECCCH
FTRFTLKELEGRLNPTVFFRCHRCFIVNLQKVKEIIPFFNGTYTLVVDDKEKSEVPVSRA
HHHHHHHHHCCCCCCEEEEEEEHHEEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHH
QAKKLRKILGL
HHHHHHHHHCC
>Mature Secondary Structure
MKIRTLIVDDEYPARQELRFLLAEIPEIEVVGEAATASEALALIRAVDYSLLFLDIEMPG
CEEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCEEEEEEEEECCC
LSGLELAKEINALPHPPYVVFVTAYDEYALKAFEVNAVDYLLKPIEPKRLKKAVEKVKKL
CCHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHH
IQENGLPKGEEVFSAYRTTGRLDRIPAEKGGKTVLVGEQEIIYAYTEQDYVYLKTYQDKY
HHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCEEEEEEECCCEEEEEEECCCH
FTRFTLKELEGRLNPTVFFRCHRCFIVNLQKVKEIIPFFNGTYTLVVDDKEKSEVPVSRA
HHHHHHHHHCCCCCCEEEEEEEHHEEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHH
QAKKLRKILGL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]