| Definition | Carboxydothermus hydrogenoformans Z-2901 chromosome, complete genome. |
|---|---|
| Accession | NC_007503 |
| Length | 2,401,520 |
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The map label for this gene is lon [H]
Identifier: 78044069
GI number: 78044069
Start: 284456
End: 286840
Strand: Direct
Name: lon [H]
Synonym: CHY_0330
Alternate gene names: 78044069
Gene position: 284456-286840 (Clockwise)
Preceding gene: 78044943
Following gene: 78044865
Centisome position: 11.84
GC content: 46.54
Gene sequence:
>2385_bases GTGGAAACAAGGGAATTACCGCTTTTGCCATTACGGGGCCTTTTGGTTTTTCCCTATATGGTTATACATTTAGATGTAGG CCGGGAAAAATCCATTGCTGCTATAGATCAAGCAATGATTTCCGACCGCATTATTTGTCTGGCTACGCAAAAGGATGCCC AAATTGATGAGCCAACTCCGGACGATATATTTGCGGTAGGAACCATCGCCGAAATAAAGCAGCTTTTAAAACTTCCAGGA GGAACGTTAAGGGTTTTAGTTGAGGGTATCCAGCGGGCCAAAATTAAAAAGTACATAGAAAAGGAACCTTTTTTCCGCGT GGAAGTGGAGGTGACCCAGGAAGAGGTAAGTAAAACCCCGGAAATCCAGGCGTTAACCCGCAGTTTAATTTACCAGTTTG AGCAGTACGTTAAACTTTCCAAAAGAATTCCGCCGGAAACGGCCATAACCGTAGTTAATTTAGAGGAACCGGGGCGCCTG GCGGATGTGGTGGCAAGTCATTTGCCTTTAAAAATTGAAGATAAACAGAGAATCCTTGAAGCACTGGATGTAAAGAAACG GCTGGAAATTTTGCTGGAAATTTTAGCCCGGGAACTGGAAATAGTAGAAATAGAGCGGCGGATAAATTTGCGGGTTAGAA AGCAAATGGAAAAAACTCAGAAGGAGTATTATCTGCGGGAACAGCTTAAAGCCATTCAGCGGGAATTGGGGGAAAAAGAC GAAAGGGTTGCCGAAGGGGAAGAGTACCGGGAAAAAATTAAAGAAGCTAAGCTTCCGAAGGAAGTTGAGGAAAAGGCCTT AAAAGAAGTGGAAAAGTTAGAAAAAATGCCACCGATGGCTGCTGAAGCAACGGTGGTGCGAAATTACCTTGATTGGATAT TGGCTCTTCCCTGGAATCGTCGCACCAAAGACCGCCTGGATATTAAACTTGCGGAGCAGATACTGGAGGAAGACCATTAC GGGTTGGAAAAGGTTAAAGAACGAATTTTAGAATATTTGGCGGTGCGAAAACTTACCAAGAAAATGAAAGGGCCCATTCT CTGCTTTGTGGGACCGCCGGGGGTGGGTAAAACATCCCTGGCGAAATCAATCGCCCGGGCCTTAGAACGAAAATTTGTGC GTATTTCGCTGGGGGGCGTACGGGATGAAGCGGAAATCCGGGGACACCGGCGGACTTATGTGGGGGCCTTACCGGGACGC ATAATTCAGGGAATGCGCAATGCCGGAAGCCAAAACCCGGTATTTCTCCTGGATGAGATTGATAAAATGAGCATGGATTT TAGAGGTGACCCCTCGGCGGCTCTTTTAGAAGTTCTGGATCCGGAACAAAATAACAGCTTTTCGGACCATTATATTGAGC TGCCTTTTGATTTATCCCATGTCCTGTTTATTACGACTGCTAATAATTTATATAACATACCCCGTCCGCTTTTGGACCGG ATGGAAGTCATCCATATCCCTGGCTATACCGAGGAGGAGAAACTGGTCATCGCGGAAAAGTATCTTTTACCAAAGCAGCT AAAGGAACACGGTTTAAAGCCCAAAAATCTCAAAATCTCCACCAATACCTTCTTAAAAATTATTCGGGAATATACCCGGG AATCGGGAGTTAGAAATTTAGAACGGCAAATTGCCTCCCTTTGCCGGAAAGCTGCCAAAGAAATCGTCACCGATAACGTG GAGGAAGTAAAAATTACCGTAAGCAACCTGGAGAGGTATCTGGGTATACCCAAGTACCGGTACGGTATCGCGGAAGCGGA GGATGAGGTAGGGGTTGCTACCGGTCTGGCCTGGACGGAAGTGGGCGGCGATGTAATGTTTATTGAAGTTTCGGTTCTTA AAGGGAGCGGCAAGCTCTACCTTACCGGTAAATTAGGAGAAGTAATGAAAGAATCGGCGCAAGCAGGCTTTTCCTACATT CGCTCCCGGGCAAAAGAGCTGGGCATTGAAGAAAACTTCCACGAAAAATACGATTTACACATCCACGTCCCCGAGGGAGC AATTCCCAAGGACGGCCCATCGGCGGGGATAACGATGGCAACGGCTATGGTGTCGGCTTTATCGGGACAAAAGGTGCGTA AGGACGTAGCCATGACCGGGGAAATTACCTTACGGGGAAAGGTACTGCCTATTGGTGGACTTAAAGAAAAAATTTTAGCG GCCAAGCGGGCAGGAATAAAAACCATCATTATTCCCCATGAGAACCGGAAAGAACTGGATGAAATTTCTCCGCAGGTAAA ACGGGGCCTGAAGTTTATCCTGGTAAAGCACATGGATGAAGTTTTAGAGGCAGCTTTAATTCGGAAAGAAAAACCTGAAA TTGAGCCGCCGGTGCCGGCGGAAGAAAAGGAAGTCACCGAACCATCGGAGATTTCCGTGCACTAA
Upstream 100 bases:
>100_bases GCGGGAAAGGACCAATCCCTTCCTTCTTCCTTAGCTTGAACTTACTTTTTAGATTATTTTATGATAGAATAATGATACTC AAAAAGGGAGGTGGTTAGAA
Downstream 100 bases:
>100_bases AGACCACCGTTATTCGGTGGTCTTTTTATGAAAAGATTTTTTGAAAAACAAAAAGGAGAAGATCGGTAAAACTAACTTTT TCCCTGATTTGCTGCAAAAG
Product: ATP-dependent protease La
Products: NA
Alternate protein names: ATP-dependent protease La [H]
Number of amino acids: Translated: 794; Mature: 794
Protein sequence:
>794_residues METRELPLLPLRGLLVFPYMVIHLDVGREKSIAAIDQAMISDRIICLATQKDAQIDEPTPDDIFAVGTIAEIKQLLKLPG GTLRVLVEGIQRAKIKKYIEKEPFFRVEVEVTQEEVSKTPEIQALTRSLIYQFEQYVKLSKRIPPETAITVVNLEEPGRL ADVVASHLPLKIEDKQRILEALDVKKRLEILLEILARELEIVEIERRINLRVRKQMEKTQKEYYLREQLKAIQRELGEKD ERVAEGEEYREKIKEAKLPKEVEEKALKEVEKLEKMPPMAAEATVVRNYLDWILALPWNRRTKDRLDIKLAEQILEEDHY GLEKVKERILEYLAVRKLTKKMKGPILCFVGPPGVGKTSLAKSIARALERKFVRISLGGVRDEAEIRGHRRTYVGALPGR IIQGMRNAGSQNPVFLLDEIDKMSMDFRGDPSAALLEVLDPEQNNSFSDHYIELPFDLSHVLFITTANNLYNIPRPLLDR MEVIHIPGYTEEEKLVIAEKYLLPKQLKEHGLKPKNLKISTNTFLKIIREYTRESGVRNLERQIASLCRKAAKEIVTDNV EEVKITVSNLERYLGIPKYRYGIAEAEDEVGVATGLAWTEVGGDVMFIEVSVLKGSGKLYLTGKLGEVMKESAQAGFSYI RSRAKELGIEENFHEKYDLHIHVPEGAIPKDGPSAGITMATAMVSALSGQKVRKDVAMTGEITLRGKVLPIGGLKEKILA AKRAGIKTIIIPHENRKELDEISPQVKRGLKFILVKHMDEVLEAALIRKEKPEIEPPVPAEEKEVTEPSEISVH
Sequences:
>Translated_794_residues METRELPLLPLRGLLVFPYMVIHLDVGREKSIAAIDQAMISDRIICLATQKDAQIDEPTPDDIFAVGTIAEIKQLLKLPG GTLRVLVEGIQRAKIKKYIEKEPFFRVEVEVTQEEVSKTPEIQALTRSLIYQFEQYVKLSKRIPPETAITVVNLEEPGRL ADVVASHLPLKIEDKQRILEALDVKKRLEILLEILARELEIVEIERRINLRVRKQMEKTQKEYYLREQLKAIQRELGEKD ERVAEGEEYREKIKEAKLPKEVEEKALKEVEKLEKMPPMAAEATVVRNYLDWILALPWNRRTKDRLDIKLAEQILEEDHY GLEKVKERILEYLAVRKLTKKMKGPILCFVGPPGVGKTSLAKSIARALERKFVRISLGGVRDEAEIRGHRRTYVGALPGR IIQGMRNAGSQNPVFLLDEIDKMSMDFRGDPSAALLEVLDPEQNNSFSDHYIELPFDLSHVLFITTANNLYNIPRPLLDR MEVIHIPGYTEEEKLVIAEKYLLPKQLKEHGLKPKNLKISTNTFLKIIREYTRESGVRNLERQIASLCRKAAKEIVTDNV EEVKITVSNLERYLGIPKYRYGIAEAEDEVGVATGLAWTEVGGDVMFIEVSVLKGSGKLYLTGKLGEVMKESAQAGFSYI RSRAKELGIEENFHEKYDLHIHVPEGAIPKDGPSAGITMATAMVSALSGQKVRKDVAMTGEITLRGKVLPIGGLKEKILA AKRAGIKTIIIPHENRKELDEISPQVKRGLKFILVKHMDEVLEAALIRKEKPEIEPPVPAEEKEVTEPSEISVH >Mature_794_residues METRELPLLPLRGLLVFPYMVIHLDVGREKSIAAIDQAMISDRIICLATQKDAQIDEPTPDDIFAVGTIAEIKQLLKLPG GTLRVLVEGIQRAKIKKYIEKEPFFRVEVEVTQEEVSKTPEIQALTRSLIYQFEQYVKLSKRIPPETAITVVNLEEPGRL ADVVASHLPLKIEDKQRILEALDVKKRLEILLEILARELEIVEIERRINLRVRKQMEKTQKEYYLREQLKAIQRELGEKD ERVAEGEEYREKIKEAKLPKEVEEKALKEVEKLEKMPPMAAEATVVRNYLDWILALPWNRRTKDRLDIKLAEQILEEDHY GLEKVKERILEYLAVRKLTKKMKGPILCFVGPPGVGKTSLAKSIARALERKFVRISLGGVRDEAEIRGHRRTYVGALPGR IIQGMRNAGSQNPVFLLDEIDKMSMDFRGDPSAALLEVLDPEQNNSFSDHYIELPFDLSHVLFITTANNLYNIPRPLLDR MEVIHIPGYTEEEKLVIAEKYLLPKQLKEHGLKPKNLKISTNTFLKIIREYTRESGVRNLERQIASLCRKAAKEIVTDNV EEVKITVSNLERYLGIPKYRYGIAEAEDEVGVATGLAWTEVGGDVMFIEVSVLKGSGKLYLTGKLGEVMKESAQAGFSYI RSRAKELGIEENFHEKYDLHIHVPEGAIPKDGPSAGITMATAMVSALSGQKVRKDVAMTGEITLRGKVLPIGGLKEKILA AKRAGIKTIIIPHENRKELDEISPQVKRGLKFILVKHMDEVLEAALIRKEKPEIEPPVPAEEKEVTEPSEISVH
Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced
COG id: COG0466
COG function: function code O; ATP-dependent Lon protease, bacterial type
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Lon domain [H]
Homologues:
Organism=Homo sapiens, GI31377667, Length=761, Percent_Identity=41.5243101182654, Blast_Score=588, Evalue=1e-168, Organism=Homo sapiens, GI21396489, Length=767, Percent_Identity=40.8083441981747, Blast_Score=578, Evalue=1e-165, Organism=Escherichia coli, GI1786643, Length=763, Percent_Identity=56.7496723460026, Blast_Score=887, Evalue=0.0, Organism=Caenorhabditis elegans, GI17505831, Length=656, Percent_Identity=41.4634146341463, Blast_Score=512, Evalue=1e-145, Organism=Caenorhabditis elegans, GI17556486, Length=792, Percent_Identity=34.3434343434343, Blast_Score=457, Evalue=1e-129, Organism=Saccharomyces cerevisiae, GI6319449, Length=734, Percent_Identity=42.5068119891008, Blast_Score=564, Evalue=1e-161, Organism=Drosophila melanogaster, GI221513036, Length=683, Percent_Identity=43.3382137628111, Blast_Score=558, Evalue=1e-159, Organism=Drosophila melanogaster, GI24666867, Length=683, Percent_Identity=43.3382137628111, Blast_Score=558, Evalue=1e-159,
Paralogues:
None
Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR008269 - InterPro: IPR004815 - InterPro: IPR003111 - InterPro: IPR008268 - InterPro: IPR001984 - InterPro: IPR015947 - InterPro: IPR020568 [H]
Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]
EC number: =3.4.21.53 [H]
Molecular weight: Translated: 90107; Mature: 90107
Theoretical pI: Translated: 7.47; Mature: 7.47
Prosite motif: PS01046 LON_SER
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure METRELPLLPLRGLLVFPYMVIHLDVGREKSIAAIDQAMISDRIICLATQKDAQIDEPTP CCCCCCCCCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCC DDIFAVGTIAEIKQLLKLPGGTLRVLVEGIQRAKIKKYIEKEPFFRVEVEVTQEEVSKTP CCEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHCCCC EIQALTRSLIYQFEQYVKLSKRIPPETAITVVNLEEPGRLADVVASHLPLKIEDKQRILE HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCEEECHHHHHHH ALDVKKRLEILLEILARELEIVEIERRINLRVRKQMEKTQKEYYLREQLKAIQRELGEKD HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH ERVAEGEEYREKIKEAKLPKEVEEKALKEVEKLEKMPPMAAEATVVRNYLDWILALPWNR HHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC RTKDRLDIKLAEQILEEDHYGLEKVKERILEYLAVRKLTKKMKGPILCFVGPPGVGKTSL CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH AKSIARALERKFVRISLGGVRDEAEIRGHRRTYVGALPGRIIQGMRNAGSQNPVFLLDEI HHHHHHHHHHHEEEEEECCCCCHHHHCCCCHHHHHCCHHHHHHHHHCCCCCCCEEEEECH DKMSMDFRGDPSAALLEVLDPEQNNSFSDHYIELPFDLSHVLFITTANNLYNIPRPLLDR HHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCCCHHHHCC MEVIHIPGYTEEEKLVIAEKYLLPKQLKEHGLKPKNLKISTNTFLKIIREYTRESGVRNL CEEEECCCCCCCCCEEHHHHHHCHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHH ERQIASLCRKAAKEIVTDNVEEVKITVSNLERYLGIPKYRYGIAEAEDEVGVATGLAWTE HHHHHHHHHHHHHHHHHCCHHHEEEEHHHHHHHHCCCHHHCCCCCCCCCCCHHHCCHHHH VGGDVMFIEVSVLKGSGKLYLTGKLGEVMKESAQAGFSYIRSRAKELGIEENFHEKYDLH CCCCEEEEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE IHVPEGAIPKDGPSAGITMATAMVSALSGQKVRKDVAMTGEITLRGKVLPIGGLKEKILA EECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHEECEEEEEEEEEECCCHHHHHHH AKRAGIKTIIIPHENRKELDEISPQVKRGLKFILVKHMDEVLEAALIRKEKPEIEPPVPA HHHCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC EEKEVTEPSEISVH CCCCCCCCCCCCCC >Mature Secondary Structure METRELPLLPLRGLLVFPYMVIHLDVGREKSIAAIDQAMISDRIICLATQKDAQIDEPTP CCCCCCCCCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCC DDIFAVGTIAEIKQLLKLPGGTLRVLVEGIQRAKIKKYIEKEPFFRVEVEVTQEEVSKTP CCEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHCCCC EIQALTRSLIYQFEQYVKLSKRIPPETAITVVNLEEPGRLADVVASHLPLKIEDKQRILE HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCEEECHHHHHHH ALDVKKRLEILLEILARELEIVEIERRINLRVRKQMEKTQKEYYLREQLKAIQRELGEKD HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH ERVAEGEEYREKIKEAKLPKEVEEKALKEVEKLEKMPPMAAEATVVRNYLDWILALPWNR HHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC RTKDRLDIKLAEQILEEDHYGLEKVKERILEYLAVRKLTKKMKGPILCFVGPPGVGKTSL CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH AKSIARALERKFVRISLGGVRDEAEIRGHRRTYVGALPGRIIQGMRNAGSQNPVFLLDEI HHHHHHHHHHHEEEEEECCCCCHHHHCCCCHHHHHCCHHHHHHHHHCCCCCCCEEEEECH DKMSMDFRGDPSAALLEVLDPEQNNSFSDHYIELPFDLSHVLFITTANNLYNIPRPLLDR HHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCCCHHHHCC MEVIHIPGYTEEEKLVIAEKYLLPKQLKEHGLKPKNLKISTNTFLKIIREYTRESGVRNL CEEEECCCCCCCCCEEHHHHHHCHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHH ERQIASLCRKAAKEIVTDNVEEVKITVSNLERYLGIPKYRYGIAEAEDEVGVATGLAWTE HHHHHHHHHHHHHHHHHCCHHHEEEEHHHHHHHHCCCHHHCCCCCCCCCCCHHHCCHHHH VGGDVMFIEVSVLKGSGKLYLTGKLGEVMKESAQAGFSYIRSRAKELGIEENFHEKYDLH CCCCEEEEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE IHVPEGAIPKDGPSAGITMATAMVSALSGQKVRKDVAMTGEITLRGKVLPIGGLKEKILA EECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHEECEEEEEEEEEECCCHHHHHHH AKRAGIKTIIIPHENRKELDEISPQVKRGLKFILVKHMDEVLEAALIRKEKPEIEPPVPA HHHCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC EEKEVTEPSEISVH CCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA