Click here to switch to the map view.

The map label for this gene is dapG [H]

Identifier: 78044009

GI number: 78044009

Start: 1027120

End: 1028352

Strand: Direct

Name: dapG [H]

Synonym: CHY_1155

Alternate gene names: 78044009

Gene position: 1027120-1028352 (Clockwise)

Preceding gene: 78044721

Following gene: 78044485

Centisome position: 42.77

GC content: 45.34

Gene sequence:

>1233_bases
ATGGCTAAAAAGTTTATCATTTTAAAGTTTGGCGGAACAAGTTTAAAGACGGCGGAACTCCGGGAAAAGGTAGCCCAAAA
AATAATTAATACTTTTGAATCTGGCTATCAACCGGTGGTGGTGGTATCGGCTATTGGCCGGAAGGGCGACCCTTATGCTA
CCGATACTTTGTTAAACTTTGCCTACGAGGTAAATCGGGATTTGCCACCTCGGGAAGCGGATTTATTAATGGCGTGCGGG
GAAATAATTAGCGGTGTAATTATGGTTAATACCCTGGCCAAAATGGGGTATAAAGCAAAACTGTTTACCGGTGCTCAGGC
TGGAATTATCACTGATGATAACTTTACCTCGGCATCGATTTTAAAAGTTAAAGCCGATAAGATTTTAAAAGCGGTGGATG
AAGGTTTTATCCCTGTGGTTTGCGGATTTCAGGGAGTAACGGAAGACGGCGAGGTTACCACTCTGGGACGGGGCGGAAGC
GATACTACCGCTGCGGCTTTGGGAGTTGCTTTGAAGGCCGAGTTTATTGATATTTACACCGATGTGGAAGGAATCAAAAC
GGCCGATCCGCGAATAGTTGAGGATGCTAAAACCTTAGAGGTGGTGACTTATAACGAAATTTCCCAGCTGGCGCATGAAG
GGGCTAAAGTTATTCATCCCCGGGCGGTGGAAATTGCGATGCAAAAAAATATCCCTCTGCGCATTAAATCAACCCTGACC
GACGGTGAAGGAACACTTGTCACCTCCCACGCTGAAGTTTACGGCGAAGTAATTGAAGTAATTCGGGACCGGATTATAAC
CGGTATTGCCCATATTCCCGGGGTAACCCAGATAAAAATTTTAAGGGAAGATACCCCGGAAATTGTGAATTTAGCCCAAA
AGGTGTTTAAAGGCTTAGCTTTGGCGGAAATAAGCGTGGATTTTATTAATATAAGTCCCGAGGGCTTGGCGTTTACCGTT
AAAGGGGAAGTGACGGAAAAAGCGGTGGATGTTTTAGAAAATATGGGTTTTACCCCGAGAATACGCCGAAATTGTGCTAA
GATAGCTGCGGTGGGGGCCGGGATGACCGGTGTGCCGGGGGTTATGGCTAAAATTGTGGAAGCCTTAACGCGGGAACAAA
TTGAAATTCTCCAATCCACCGACTCGTACACTACCATCTGGGTACTGGTGGATGGGGAAAATATGGAAAAAGCTGTTAGG
GCTATTCACAAAGCTTTTAAACTAAACGAATAA

Upstream 100 bases:

>100_bases
TTAAATCTTTGGGTTGTTGCGGACCAATTACGGAAGGGTGCAGCTACAAATGCTGTTCAGATTGCTGAACTACTAATAAA
GTACGGGTGTGTGAAGCAAA

Downstream 100 bases:

>100_bases
AAAATTAAAAGAAGGTGAAAAGATGGCAGTGTTTGGACGATTGTTAACCGCTATGGTAACCCCTTTTGATCGGGATGGGA
AGGTTAACCTGGAGCAGGCA

Product: aspartate kinase I

Products: NA

Alternate protein names: Aspartate kinase 1; Aspartokinase I [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MAKKFIILKFGGTSLKTAELREKVAQKIINTFESGYQPVVVVSAIGRKGDPYATDTLLNFAYEVNRDLPPREADLLMACG
EIISGVIMVNTLAKMGYKAKLFTGAQAGIITDDNFTSASILKVKADKILKAVDEGFIPVVCGFQGVTEDGEVTTLGRGGS
DTTAAALGVALKAEFIDIYTDVEGIKTADPRIVEDAKTLEVVTYNEISQLAHEGAKVIHPRAVEIAMQKNIPLRIKSTLT
DGEGTLVTSHAEVYGEVIEVIRDRIITGIAHIPGVTQIKILREDTPEIVNLAQKVFKGLALAEISVDFINISPEGLAFTV
KGEVTEKAVDVLENMGFTPRIRRNCAKIAAVGAGMTGVPGVMAKIVEALTREQIEILQSTDSYTTIWVLVDGENMEKAVR
AIHKAFKLNE

Sequences:

>Translated_410_residues
MAKKFIILKFGGTSLKTAELREKVAQKIINTFESGYQPVVVVSAIGRKGDPYATDTLLNFAYEVNRDLPPREADLLMACG
EIISGVIMVNTLAKMGYKAKLFTGAQAGIITDDNFTSASILKVKADKILKAVDEGFIPVVCGFQGVTEDGEVTTLGRGGS
DTTAAALGVALKAEFIDIYTDVEGIKTADPRIVEDAKTLEVVTYNEISQLAHEGAKVIHPRAVEIAMQKNIPLRIKSTLT
DGEGTLVTSHAEVYGEVIEVIRDRIITGIAHIPGVTQIKILREDTPEIVNLAQKVFKGLALAEISVDFINISPEGLAFTV
KGEVTEKAVDVLENMGFTPRIRRNCAKIAAVGAGMTGVPGVMAKIVEALTREQIEILQSTDSYTTIWVLVDGENMEKAVR
AIHKAFKLNE
>Mature_409_residues
AKKFIILKFGGTSLKTAELREKVAQKIINTFESGYQPVVVVSAIGRKGDPYATDTLLNFAYEVNRDLPPREADLLMACGE
IISGVIMVNTLAKMGYKAKLFTGAQAGIITDDNFTSASILKVKADKILKAVDEGFIPVVCGFQGVTEDGEVTTLGRGGSD
TTAAALGVALKAEFIDIYTDVEGIKTADPRIVEDAKTLEVVTYNEISQLAHEGAKVIHPRAVEIAMQKNIPLRIKSTLTD
GEGTLVTSHAEVYGEVIEVIRDRIITGIAHIPGVTQIKILREDTPEIVNLAQKVFKGLALAEISVDFINISPEGLAFTVK
GEVTEKAVDVLENMGFTPRIRRNCAKIAAVGAGMTGVPGVMAKIVEALTREQIEILQSTDSYTTIWVLVDGENMEKAVRA
IHKAFKLNE

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartokinase family [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=286, Percent_Identity=31.4685314685315, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790455, Length=351, Percent_Identity=29.0598290598291, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790376, Length=284, Percent_Identity=27.8169014084507, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320893, Length=189, Percent_Identity=34.3915343915344, Blast_Score=102, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 44276; Mature: 44145

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00324 ASPARTOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKFIILKFGGTSLKTAELREKVAQKIINTFESGYQPVVVVSAIGRKGDPYATDTLLNF
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHH
AYEVNRDLPPREADLLMACGEIISGVIMVNTLAKMGYKAKLFTGAQAGIITDDNFTSASI
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCEEE
LKVKADKILKAVDEGFIPVVCGFQGVTEDGEVTTLGRGGSDTTAAALGVALKAEFIDIYT
EEEHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHC
DVEGIKTADPRIVEDAKTLEVVTYNEISQLAHEGAKVIHPRAVEIAMQKNIPLRIKSTLT
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCEECCHHEEEEEECCCCEEEEEEEE
DGEGTLVTSHAEVYGEVIEVIRDRIITGIAHIPGVTQIKILREDTPEIVNLAQKVFKGLA
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCE
LAEISVDFINISPEGLAFTVKGEVTEKAVDVLENMGFTPRIRRNCAKIAAVGAGMTGVPG
EEEEEEEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHH
VMAKIVEALTREQIEILQSTDSYTTIWVLVDGENMEKAVRAIHKAFKLNE
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKKFIILKFGGTSLKTAELREKVAQKIINTFESGYQPVVVVSAIGRKGDPYATDTLLNF
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHH
AYEVNRDLPPREADLLMACGEIISGVIMVNTLAKMGYKAKLFTGAQAGIITDDNFTSASI
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCEEE
LKVKADKILKAVDEGFIPVVCGFQGVTEDGEVTTLGRGGSDTTAAALGVALKAEFIDIYT
EEEHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHC
DVEGIKTADPRIVEDAKTLEVVTYNEISQLAHEGAKVIHPRAVEIAMQKNIPLRIKSTLT
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCEECCHHEEEEEECCCCEEEEEEEE
DGEGTLVTSHAEVYGEVIEVIRDRIITGIAHIPGVTQIKILREDTPEIVNLAQKVFKGLA
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCE
LAEISVDFINISPEGLAFTVKGEVTEKAVDVLENMGFTPRIRRNCAKIAAVGAGMTGVPG
EEEEEEEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHH
VMAKIVEALTREQIEILQSTDSYTTIWVLVDGENMEKAVRAIHKAFKLNE
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377 [H]