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The map label for this gene is thiL [H]

Identifier: 78043238

GI number: 78043238

Start: 660140

End: 661120

Strand: Direct

Name: thiL [H]

Synonym: CHY_0749

Alternate gene names: 78043238

Gene position: 660140-661120 (Clockwise)

Preceding gene: 78042771

Following gene: 78044135

Centisome position: 27.49

GC content: 44.75

Gene sequence:

>981_bases
ATGGAAGTTACAAAGATTGGGGAAGAAGGGGTTATAGCTATTGCCAAGAAAGCTACTGAAGTATCCCCCGGCGTTATTTT
GGGAATCGGGGATGATGCAGCGGTAGTTGAAATTAAGGGAAAGCTCCTTGTAACCACTGATTTACTGGTGGAAAACGTCC
ATTTTAAGCGAAATTACACGAAGCCGGAAATATTGGGGAAAAAGGCTTTGGCGGTAAATTTAAGCGACATTGCGGCAATG
GGCGGCATACCTCGCTTTTGTCTGGTGAGCCTGGCTTTGCCCAAAACCACTGAAGTTAATTTTGTTGAAGGCTTTTACCA
GGGATTAAAAAGTATGGCTAAAGAGTATGGGGTTACTTTGATTGGTGGCGATACTACCGGAGCTGGCAGTGAAATAATGG
TGGCGGTTACGGTACTGGGGGAAGCCTTAGAAGAAGGAGTTTTAACCCGAAGCGGAGCAAAACCCGGGGATGGGGTATAT
GTCTCCGGTTATCTTGGCGATAGCGCGGCAGGACTTTATTTGCTTTTAAAGGAAAAATTGGGTTTATTGCCGGAAGAAGT
GGAAAAATATCTGATTTCCCGGCACCTGGAACCCGAACCCAGATTGGAGTTAGGCCAGCTTCTCTGCCGGGAAAAATTTG
CTACTTCTACTAATGATTTAAGTGACGGTCTTGTGAAAAAACTTCAGGAAATAGCGCGGGCTTCTGGGGTTGAAATTACG
ATTAACCGGGAGAAAATACCTTTGTCTTTTGCTCTTTTAACATTCTGCCAGCAATTTACCTTAAAACCGTTGGATTTTGC
TTTACACGGCGGCGAAGATTATGAACTTTTGTTTACCGTGCCTGCCGAAAAGGAGGAAGAGCTTTTTAAACTGGACTTAC
CGCTGTTTAAAATTGGTATGGTTACGGGATATGACGAGCGGGGAAGGGTAAAAGCTGAAGATGGGGTAGTCTTGCAGGAT
AGGGGTTTCCAGCATTTTTAA

Upstream 100 bases:

>100_bases
GGGAGTTTTCTGGTAAATTTTATAGATTCTCTTTATAATTTAACTAAAGAAGAGTTTTTGGAGCTAACTACGGAAAAAGT
TCAAGGGCTACGGTGAGAAA

Downstream 100 bases:

>100_bases
TTATGAGGTGGAAGATATTTGCGCAGGGTAAAAATTATTTTTTTAACTTTTTTACTGGCAATTACCTTAACTAAAGCTTT
TGCCAGTGCAGCTTCTCCGG

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MEVTKIGEEGVIAIAKKATEVSPGVILGIGDDAAVVEIKGKLLVTTDLLVENVHFKRNYTKPEILGKKALAVNLSDIAAM
GGIPRFCLVSLALPKTTEVNFVEGFYQGLKSMAKEYGVTLIGGDTTGAGSEIMVAVTVLGEALEEGVLTRSGAKPGDGVY
VSGYLGDSAAGLYLLLKEKLGLLPEEVEKYLISRHLEPEPRLELGQLLCREKFATSTNDLSDGLVKKLQEIARASGVEIT
INREKIPLSFALLTFCQQFTLKPLDFALHGGEDYELLFTVPAEKEEELFKLDLPLFKIGMVTGYDERGRVKAEDGVVLQD
RGFQHF

Sequences:

>Translated_326_residues
MEVTKIGEEGVIAIAKKATEVSPGVILGIGDDAAVVEIKGKLLVTTDLLVENVHFKRNYTKPEILGKKALAVNLSDIAAM
GGIPRFCLVSLALPKTTEVNFVEGFYQGLKSMAKEYGVTLIGGDTTGAGSEIMVAVTVLGEALEEGVLTRSGAKPGDGVY
VSGYLGDSAAGLYLLLKEKLGLLPEEVEKYLISRHLEPEPRLELGQLLCREKFATSTNDLSDGLVKKLQEIARASGVEIT
INREKIPLSFALLTFCQQFTLKPLDFALHGGEDYELLFTVPAEKEEELFKLDLPLFKIGMVTGYDERGRVKAEDGVVLQD
RGFQHF
>Mature_326_residues
MEVTKIGEEGVIAIAKKATEVSPGVILGIGDDAAVVEIKGKLLVTTDLLVENVHFKRNYTKPEILGKKALAVNLSDIAAM
GGIPRFCLVSLALPKTTEVNFVEGFYQGLKSMAKEYGVTLIGGDTTGAGSEIMVAVTVLGEALEEGVLTRSGAKPGDGVY
VSGYLGDSAAGLYLLLKEKLGLLPEEVEKYLISRHLEPEPRLELGQLLCREKFATSTNDLSDGLVKKLQEIARASGVEIT
INREKIPLSFALLTFCQQFTLKPLDFALHGGEDYELLFTVPAEKEEELFKLDLPLFKIGMVTGYDERGRVKAEDGVVLQD
RGFQHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=313, Percent_Identity=41.5335463258786, Blast_Score=178, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35378; Mature: 35378

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVTKIGEEGVIAIAKKATEVSPGVILGIGDDAAVVEIKGKLLVTTDLLVENVHFKRNYT
CCCCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEECCCEEEEEHHHHHCCHHCCCCC
KPEILGKKALAVNLSDIAAMGGIPRFCLVSLALPKTTEVNFVEGFYQGLKSMAKEYGVTL
CHHHHCCCEEEEEHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEE
IGGDTTGAGSEIMVAVTVLGEALEEGVLTRSGAKPGDGVYVSGYLGDSAAGLYLLLKEKL
ECCCCCCCCCHHEEHHHHHHHHHHCCCEECCCCCCCCCEEEEEECCCCCCHHHEEEHHHH
GLLPEEVEKYLISRHLEPEPRLELGQLLCREKFATSTNDLSDGLVKKLQEIARASGVEIT
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEE
INREKIPLSFALLTFCQQFTLKPLDFALHGGEDYELLFTVPAEKEEELFKLDLPLFKIGM
EECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCCCHHEEECCCEEEEEE
VTGYDERGRVKAEDGVVLQDRGFQHF
EECCCCCCCEECCCCEEEECCCCCCC
>Mature Secondary Structure
MEVTKIGEEGVIAIAKKATEVSPGVILGIGDDAAVVEIKGKLLVTTDLLVENVHFKRNYT
CCCCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEECCCEEEEEHHHHHCCHHCCCCC
KPEILGKKALAVNLSDIAAMGGIPRFCLVSLALPKTTEVNFVEGFYQGLKSMAKEYGVTL
CHHHHCCCEEEEEHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEE
IGGDTTGAGSEIMVAVTVLGEALEEGVLTRSGAKPGDGVYVSGYLGDSAAGLYLLLKEKL
ECCCCCCCCCHHEEHHHHHHHHHHCCCEECCCCCCCCCEEEEEECCCCCCHHHEEEHHHH
GLLPEEVEKYLISRHLEPEPRLELGQLLCREKFATSTNDLSDGLVKKLQEIARASGVEIT
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEE
INREKIPLSFALLTFCQQFTLKPLDFALHGGEDYELLFTVPAEKEEELFKLDLPLFKIGM
EECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCCCHHEEECCCEEEEEE
VTGYDERGRVKAEDGVVLQDRGFQHF
EECCCCCCCEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377; 8419296 [H]