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The map label for this gene is etfA2 [H]

Identifier: 78043026

GI number: 78043026

Start: 1212454

End: 1213410

Strand: Direct

Name: etfA2 [H]

Synonym: CHY_1353

Alternate gene names: 78043026

Gene position: 1212454-1213410 (Clockwise)

Preceding gene: 78045170

Following gene: 78044790

Centisome position: 50.49

GC content: 50.57

Gene sequence:

>957_bases
ATGGGTAAAGTATGGGTAGTAGCAGAGCAAAGGGAAGGTAAGTTAAAGAAAGTAACCTTTGAGATGGTAACTTTGGCCCG
GCAAATAGGGGGAGAGGTTGAAGGGGTAGTAATCGGAAAAGACGTAAAAGGCCTGGCTTCTGAACTTGGGGAATACGGAG
TAGGGAAAGTATATGTAGCCGACCATCCGGATTTAGAGCAGTACACCACCGCCAAATACACCCGGGTACTGGCGGAATTA
ATCAATAAAGAAAAGCCGGAAGTAGTGTTAATTGCCAACTCCGCTCAGGGGAGGGACTTTGCACCGCGGACAGCCCAGCG
GGTAGGAGCGGGACAGGTAAGCGACATCACCGGTTACGAAGAAGGAGTCTTTGTCCGGCCCATTTACGCCGGGAAAGCTT
ATACCAAAGTGGGGGCCACCAGCCATCCGTTAATAGTAACGGTACGGCCCAACGTATTTTCGGCAGCGGAAAAGACAGGC
GGGCAAGCTGCAATTGAAGAAGTGGCGGTCAGCTTTATGCCGGAAGATTTAAAAGCCATAGTAAAGGAAGTAGTCAAGCA
GGTATCGGGACGTCCCGAATTAACCGAAGCGGATATCATAGTATCGGGTGGTCGGGGGATGAAAGGTCCGGAGAACTTCA
AGCTGTTGGAAGATTTGGCGGACGTTTTAGGGGCAGCGGTAGGGGCCTCCCGGGCAGCGGTAGATGCCGGCTGGCGGGAG
CACCGGTACCAGGTAGGCCAGACTGGTAAGACCGTATCCCCCAGTTTGTATATCGCCGTAGGTATTTCCGGGGCAATTCA
GCACTTAGCCGGGATGGGCAGCTCCAAGGTAATAGTAGCCATCAACAAAGACCCGGAAGCTAACATCTTTAAAGTTGCCG
ATTACGGTATTGTTGGCGATTTGTTTGAAATAGTTCCGCTTTTAACCGAAGAGTTTAAAAAGCTTTTAAAATCGTAA

Upstream 100 bases:

>100_bases
GCAGGCGGGGAAAATCTTCACCGATGAGCCGGCGGTAGCGGTAGCCAAGTTAGTCAAAGCCTTACGGGAAGAAGCCAAGG
TAATATAGGGGGTGGAGCTA

Downstream 100 bases:

>100_bases
CTTAAATGTAAGTGAAATGTAGAGAAATGGAAGAGGAGATTGGCTTTAATTATACTTCTTGGGGTGTAGACCAACAACTA
CACCCCCATTTTTCAACTAT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MGKVWVVAEQREGKLKKVTFEMVTLARQIGGEVEGVVIGKDVKGLASELGEYGVGKVYVADHPDLEQYTTAKYTRVLAEL
INKEKPEVVLIANSAQGRDFAPRTAQRVGAGQVSDITGYEEGVFVRPIYAGKAYTKVGATSHPLIVTVRPNVFSAAEKTG
GQAAIEEVAVSFMPEDLKAIVKEVVKQVSGRPELTEADIIVSGGRGMKGPENFKLLEDLADVLGAAVGASRAAVDAGWRE
HRYQVGQTGKTVSPSLYIAVGISGAIQHLAGMGSSKVIVAINKDPEANIFKVADYGIVGDLFEIVPLLTEEFKKLLKS

Sequences:

>Translated_318_residues
MGKVWVVAEQREGKLKKVTFEMVTLARQIGGEVEGVVIGKDVKGLASELGEYGVGKVYVADHPDLEQYTTAKYTRVLAEL
INKEKPEVVLIANSAQGRDFAPRTAQRVGAGQVSDITGYEEGVFVRPIYAGKAYTKVGATSHPLIVTVRPNVFSAAEKTG
GQAAIEEVAVSFMPEDLKAIVKEVVKQVSGRPELTEADIIVSGGRGMKGPENFKLLEDLADVLGAAVGASRAAVDAGWRE
HRYQVGQTGKTVSPSLYIAVGISGAIQHLAGMGSSKVIVAINKDPEANIFKVADYGIVGDLFEIVPLLTEEFKKLLKS
>Mature_317_residues
GKVWVVAEQREGKLKKVTFEMVTLARQIGGEVEGVVIGKDVKGLASELGEYGVGKVYVADHPDLEQYTTAKYTRVLAELI
NKEKPEVVLIANSAQGRDFAPRTAQRVGAGQVSDITGYEEGVFVRPIYAGKAYTKVGATSHPLIVTVRPNVFSAAEKTGG
QAAIEEVAVSFMPEDLKAIVKEVVKQVSGRPELTEADIIVSGGRGMKGPENFKLLEDLADVLGAAVGASRAAVDAGWREH
RYQVGQTGKTVSPSLYIAVGISGAIQHLAGMGSSKVIVAINKDPEANIFKVADYGIVGDLFEIVPLLTEEFKKLLKS

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=46.9453376205788, Blast_Score=245, Evalue=5e-65,
Organism=Homo sapiens, GI189181759, Length=263, Percent_Identity=49.8098859315589, Blast_Score=221, Evalue=5e-58,
Organism=Escherichia coli, GI1787990, Length=320, Percent_Identity=30.625, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1786226, Length=325, Percent_Identity=29.8461538461538, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI87082157, Length=233, Percent_Identity=30.4721030042918, Blast_Score=74, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=44.0514469453376, Blast_Score=229, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6325261, Length=314, Percent_Identity=35.9872611464968, Blast_Score=197, Evalue=1e-51,
Organism=Drosophila melanogaster, GI17136898, Length=307, Percent_Identity=45.6026058631922, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24652801, Length=307, Percent_Identity=45.6026058631922, Blast_Score=235, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33968; Mature: 33837

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKVWVVAEQREGKLKKVTFEMVTLARQIGGEVEGVVIGKDVKGLASELGEYGVGKVYVA
CCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCEEEEC
DHPDLEQYTTAKYTRVLAELINKEKPEVVLIANSAQGRDFAPRTAQRVGAGQVSDITGYE
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCC
EGVFVRPIYAGKAYTKVGATSHPLIVTVRPNVFSAAEKTGGQAAIEEVAVSFMPEDLKAI
CCEEEEEEECCCCEEECCCCCCCEEEEECCCHHHHHHHCCCHHHHHHHHHHCCCHHHHHH
VKEVVKQVSGRPELTEADIIVSGGRGMKGPENFKLLEDLADVLGAAVGASRAAVDAGWRE
HHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCHHH
HRYQVGQTGKTVSPSLYIAVGISGAIQHLAGMGSSKVIVAINKDPEANIFKVADYGIVGD
HHHHHCCCCCCCCCCEEEEEECHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHHHH
LFEIVPLLTEEFKKLLKS
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GKVWVVAEQREGKLKKVTFEMVTLARQIGGEVEGVVIGKDVKGLASELGEYGVGKVYVA
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCEEEEC
DHPDLEQYTTAKYTRVLAELINKEKPEVVLIANSAQGRDFAPRTAQRVGAGQVSDITGYE
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCC
EGVFVRPIYAGKAYTKVGATSHPLIVTVRPNVFSAAEKTGGQAAIEEVAVSFMPEDLKAI
CCEEEEEEECCCCEEECCCCCCCEEEEECCCHHHHHHHCCCHHHHHHHHHHCCCHHHHHH
VKEVVKQVSGRPELTEADIIVSGGRGMKGPENFKLLEDLADVLGAAVGASRAAVDAGWRE
HHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCHHH
HRYQVGQTGKTVSPSLYIAVGISGAIQHLAGMGSSKVIVAINKDPEANIFKVADYGIVGD
HHHHHCCCCCCCCCCEEEEEECHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHHHH
LFEIVPLLTEEFKKLLKS
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]