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The map label for this gene is acuC [H]

Identifier: 78043001

GI number: 78043001

Start: 147480

End: 148631

Strand: Direct

Name: acuC [H]

Synonym: CHY_0174

Alternate gene names: 78043001

Gene position: 147480-148631 (Clockwise)

Preceding gene: 78043747

Following gene: 78045145

Centisome position: 6.14

GC content: 49.39

Gene sequence:

>1152_bases
ATGAGCGGAAAGGCGTATTTAATATACAGCGACGACTATTTAAGTTACCGCTTAGCGGAAGACCACCCCTTGAATCCCCA
GCGGTATGCTTTAGCTGTGGAATTGATGAAAATAGCTGAAGTTTTAAAGGAGGAAGAAATAATCCCACCCCGTTCGGCTA
CGTTAAAAGAACTGTATTTGGTACACGACCCGGCTTATGTGGAAGCGGTAATGAATTTAAGTAAAAATCCGGAAAACGTG
AACGGCAGCCGCTTTGGTCTGGGTTCGGAAGACAATCCGGTTTTTTCCGGGATGCACGAAGCAGCGGCGCTGGTGGCGGG
GGGTTCAGCCCTGGGTGCGGAACTGATTTATGAAGGAGAAGCGGACCACGTTTTCAATATAGCGGGAGGGCTACACCATG
CCCTTCGGGATGCTGCGTCGGGTTTTTGCATTTATAATGATTTAGCGGTAGCCATAGCCAAGTTCAGGGAAAAAGGACTC
AAAGTGGCGTACGTAGACCTGGATGCCCACCATGGAGATGGGGTCCAGTGGCTTTTTTATAGTGACCCGGGGGTTTTAAC
CATATCTATTCATGAAACGGGAAGATATCTCTTCCCCGGTACCGGTTCGATAACCGAGTTAGGGGAAGGAGCGGCTTACG
GCACCAAAATTAATATTCCTTTAGAGCCTTATACCGAAGATGATTCGTGGCTATGGGCTTTGGAGGAAATTGTTCCGGAG
CTTATCAGAAAGTTTAAACCGGACATCCTGGTTACCCAGCACGGGTGTGATTCCCACCGCTTTGACCCTTTAACCCATTT
AGCCAATACTACTTTGGCTTTTCAGGAATCGGCCAAGCTCTTACATGAATTAGCCCATGAAGTCTGCGGGGGACGCTGGC
TTGCCGGCGGGGGCGGGGGATACGACTACTGGCGGGTGGTGCCCCGGGCCTGGACAATAGTTTGGGCTGAGATGACCGAG
CGCTCTCTACCCTATGATGTTCCCGCCACTTTCTGGCGTAAATATGAGAGTAAAGCCGGGGTGTTTTTACCGAGAACTTT
TTTAGATGAAGGAAGTTCCGGGATTCCGTTAGGGCGCCGGCGGGAAATTACTTCAAAAAACCAAAGGACGGTGGAAAGGT
TAAAAAACGCTTTAACTCTCTTTTGGAGTTAA

Upstream 100 bases:

>100_bases
CTTGTGATGCGGGTTGAAACGATGAACACCAAACCAATCATTGACCGCATTCGGGCTAAAGGATTTACACTGATCAACCC
CTTTGGCGAGGTATAAGTAA

Downstream 100 bases:

>100_bases
AGCATTTTTTTATAAAAAGGAGGTTAGCAACAGTTGGAATTAATATTGCAAAAATAAAATTTAAAAAATATTTTGAAGAC
CGCCAGGACTTTCGGTAACC

Product: acetoin utilization protein AcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSGKAYLIYSDDYLSYRLAEDHPLNPQRYALAVELMKIAEVLKEEEIIPPRSATLKELYLVHDPAYVEAVMNLSKNPENV
NGSRFGLGSEDNPVFSGMHEAAALVAGGSALGAELIYEGEADHVFNIAGGLHHALRDAASGFCIYNDLAVAIAKFREKGL
KVAYVDLDAHHGDGVQWLFYSDPGVLTISIHETGRYLFPGTGSITELGEGAAYGTKINIPLEPYTEDDSWLWALEEIVPE
LIRKFKPDILVTQHGCDSHRFDPLTHLANTTLAFQESAKLLHELAHEVCGGRWLAGGGGGYDYWRVVPRAWTIVWAEMTE
RSLPYDVPATFWRKYESKAGVFLPRTFLDEGSSGIPLGRRREITSKNQRTVERLKNALTLFWS

Sequences:

>Translated_383_residues
MSGKAYLIYSDDYLSYRLAEDHPLNPQRYALAVELMKIAEVLKEEEIIPPRSATLKELYLVHDPAYVEAVMNLSKNPENV
NGSRFGLGSEDNPVFSGMHEAAALVAGGSALGAELIYEGEADHVFNIAGGLHHALRDAASGFCIYNDLAVAIAKFREKGL
KVAYVDLDAHHGDGVQWLFYSDPGVLTISIHETGRYLFPGTGSITELGEGAAYGTKINIPLEPYTEDDSWLWALEEIVPE
LIRKFKPDILVTQHGCDSHRFDPLTHLANTTLAFQESAKLLHELAHEVCGGRWLAGGGGGYDYWRVVPRAWTIVWAEMTE
RSLPYDVPATFWRKYESKAGVFLPRTFLDEGSSGIPLGRRREITSKNQRTVERLKNALTLFWS
>Mature_382_residues
SGKAYLIYSDDYLSYRLAEDHPLNPQRYALAVELMKIAEVLKEEEIIPPRSATLKELYLVHDPAYVEAVMNLSKNPENVN
GSRFGLGSEDNPVFSGMHEAAALVAGGSALGAELIYEGEADHVFNIAGGLHHALRDAASGFCIYNDLAVAIAKFREKGLK
VAYVDLDAHHGDGVQWLFYSDPGVLTISIHETGRYLFPGTGSITELGEGAAYGTKINIPLEPYTEDDSWLWALEEIVPEL
IRKFKPDILVTQHGCDSHRFDPLTHLANTTLAFQESAKLLHELAHEVCGGRWLAGGGGGYDYWRVVPRAWTIVWAEMTER
SLPYDVPATFWRKYESKAGVFLPRTFLDEGSSGIPLGRRREITSKNQRTVERLKNALTLFWS

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128860, Length=337, Percent_Identity=31.4540059347181, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI8923769, Length=323, Percent_Identity=29.1021671826625, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI13128862, Length=340, Percent_Identity=30, Blast_Score=161, Evalue=7e-40,
Organism=Homo sapiens, GI293336691, Length=337, Percent_Identity=29.9703264094956, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI262073092, Length=234, Percent_Identity=31.1965811965812, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI262073088, Length=201, Percent_Identity=31.8407960199005, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI153085395, Length=301, Percent_Identity=30.5647840531561, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI17158039, Length=246, Percent_Identity=32.520325203252, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI30795202, Length=246, Percent_Identity=32.520325203252, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI30795204, Length=246, Percent_Identity=32.520325203252, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI20070354, Length=316, Percent_Identity=29.746835443038, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI169234807, Length=207, Percent_Identity=31.8840579710145, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI148539870, Length=207, Percent_Identity=31.8840579710145, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI62750347, Length=317, Percent_Identity=29.3375394321767, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI62750349, Length=317, Percent_Identity=29.3375394321767, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI13128864, Length=331, Percent_Identity=27.7945619335347, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI226529806, Length=234, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI217272877, Length=292, Percent_Identity=24.3150684931507, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI209862883, Length=269, Percent_Identity=23.4200743494424, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17508561, Length=323, Percent_Identity=31.2693498452012, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17534739, Length=327, Percent_Identity=31.8042813455657, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17561978, Length=332, Percent_Identity=30.421686746988, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI193209491, Length=302, Percent_Identity=27.8145695364238, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17540334, Length=330, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193206283, Length=321, Percent_Identity=27.4143302180685, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17540332, Length=321, Percent_Identity=27.4143302180685, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17537347, Length=263, Percent_Identity=29.6577946768061, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193207430, Length=269, Percent_Identity=26.7657992565056, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI25154020, Length=388, Percent_Identity=22.9381443298969, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25154022, Length=388, Percent_Identity=22.9381443298969, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321244, Length=319, Percent_Identity=34.1692789968652, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6323999, Length=333, Percent_Identity=31.2312312312312, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324307, Length=282, Percent_Identity=30.1418439716312, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6325325, Length=213, Percent_Identity=30.5164319248826, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24644244, Length=337, Percent_Identity=31.4540059347181, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24657891, Length=327, Percent_Identity=32.7217125382263, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24642144, Length=291, Percent_Identity=29.8969072164948, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24642146, Length=291, Percent_Identity=29.8969072164948, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24642142, Length=291, Percent_Identity=29.8969072164948, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281360899, Length=291, Percent_Identity=29.8969072164948, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281360799, Length=330, Percent_Identity=28.4848484848485, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281360801, Length=330, Percent_Identity=28.4848484848485, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24641720, Length=330, Percent_Identity=28.4848484848485, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24649807, Length=181, Percent_Identity=28.1767955801105, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 42642; Mature: 42510

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKAYLIYSDDYLSYRLAEDHPLNPQRYALAVELMKIAEVLKEEEIIPPRSATLKELYL
CCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEE
VHDPAYVEAVMNLSKNPENVNGSRFGLGSEDNPVFSGMHEAAALVAGGSALGAELIYEGE
EECHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCEEEECCC
ADHVFNIAGGLHHALRDAASGFCIYNDLAVAIAKFREKGLKVAYVDLDAHHGDGVQWLFY
CCCEEEHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEE
SDPGVLTISIHETGRYLFPGTGSITELGEGAAYGTKINIPLEPYTEDDSWLWALEEIVPE
CCCCEEEEEEECCCCEEECCCCCHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHH
LIRKFKPDILVTQHGCDSHRFDPLTHLANTTLAFQESAKLLHELAHEVCGGRWLAGGGGG
HHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
YDYWRVVPRAWTIVWAEMTERSLPYDVPATFWRKYESKAGVFLPRTFLDEGSSGIPLGRR
CHHHHHHCHHEEEEEEEHHCCCCCCCCCHHHHHHHHCCCCEEEEHHHHCCCCCCCCCCCC
REITSKNQRTVERLKNALTLFWS
CCCCCCHHHHHHHHHHHHEEECC
>Mature Secondary Structure 
SGKAYLIYSDDYLSYRLAEDHPLNPQRYALAVELMKIAEVLKEEEIIPPRSATLKELYL
CCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEE
VHDPAYVEAVMNLSKNPENVNGSRFGLGSEDNPVFSGMHEAAALVAGGSALGAELIYEGE
EECHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCEEEECCC
ADHVFNIAGGLHHALRDAASGFCIYNDLAVAIAKFREKGLKVAYVDLDAHHGDGVQWLFY
CCCEEEHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEE
SDPGVLTISIHETGRYLFPGTGSITELGEGAAYGTKINIPLEPYTEDDSWLWALEEIVPE
CCCCEEEEEEECCCCEEECCCCCHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHH
LIRKFKPDILVTQHGCDSHRFDPLTHLANTTLAFQESAKLLHELAHEVCGGRWLAGGGGG
HHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
YDYWRVVPRAWTIVWAEMTERSLPYDVPATFWRKYESKAGVFLPRTFLDEGSSGIPLGRR
CHHHHHHCHHEEEEEEEHHCCCCCCCCCHHHHHHHHCCCCEEEEHHHHCCCCCCCCCCCC
REITSKNQRTVERLKNALTLFWS
CCCCCCHHHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]