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The map label for this gene is tdk [H]

Identifier: 78042944

GI number: 78042944

Start: 504169

End: 504720

Strand: Direct

Name: tdk [H]

Synonym: CHY_0585

Alternate gene names: 78042944

Gene position: 504169-504720 (Clockwise)

Preceding gene: 78043678

Following gene: 78045184

Centisome position: 20.99

GC content: 42.93

Gene sequence:

>552_bases
ATGGGGAGAATTGAGGTCATTACCGGTCCAATGTTCTCCGGGAAATCGGAGGAACTGGTGCGCAGAGCCTTGCGGCTTAT
GTATGCTAAGAAAAAAGTAATAGCATTTCACCATGCTCTGGATAATCGCTTCGGGCATAAAAAAATAGTCAGTAGGAGCG
GGTTTGAACTGGAATCCTACCCGGTTCAAAATTTTGCTTTTGAGGTAATCTGGGATTTAGCAAAAGATTATGATGCGGTT
TTAGTTGATGAAGCTCAATTTTTTAGTGACGAACTGGTGGATACCTGTTTAAATTTGCGCCGGCGTTCGAAAATTGTGGT
GGTTTCCGGTTTGGATTTGGATGTTTACGAAAATCCTTTTGGCCCAATGCCGAAACTGTTAGCTCTGGCTGACAGGGTGG
ATAAATTAAAAGCCGTTTGTTTTGAATGCGGAGAGGAAGCTACGATATCATATCGTTTATCGGGGGAGAAGGAACAAATA
GTGGTTGGAGACAAAAATTACATCGCCCTGTGTTACCGCTGTTATTATGCCAAGAAAAAAGAAGAGCGGTAG

Upstream 100 bases:

>100_bases
TCCCCTGCCAGCAGGACACCTGGGAGAAACCGATATTTACGGGGCCCAGCAGCATGCACCGCTTTTAAATGCAGAACTTG
AACTGTAAAGGAGAGGCAAA

Downstream 100 bases:

>100_bases
AACGCTACCGCTCGTAGTAACGGCATTTTTCCCGGGAACAGCCGTGGGGGTGCTTTAGATATTCGCTGCATGATATTTTA
TAATTGAGGGGCAGATTGAA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MGRIEVITGPMFSGKSEELVRRALRLMYAKKKVIAFHHALDNRFGHKKIVSRSGFELESYPVQNFAFEVIWDLAKDYDAV
LVDEAQFFSDELVDTCLNLRRRSKIVVVSGLDLDVYENPFGPMPKLLALADRVDKLKAVCFECGEEATISYRLSGEKEQI
VVGDKNYIALCYRCYYAKKKEER

Sequences:

>Translated_183_residues
MGRIEVITGPMFSGKSEELVRRALRLMYAKKKVIAFHHALDNRFGHKKIVSRSGFELESYPVQNFAFEVIWDLAKDYDAV
LVDEAQFFSDELVDTCLNLRRRSKIVVVSGLDLDVYENPFGPMPKLLALADRVDKLKAVCFECGEEATISYRLSGEKEQI
VVGDKNYIALCYRCYYAKKKEER
>Mature_182_residues
GRIEVITGPMFSGKSEELVRRALRLMYAKKKVIAFHHALDNRFGHKKIVSRSGFELESYPVQNFAFEVIWDLAKDYDAVL
VDEAQFFSDELVDTCLNLRRRSKIVVVSGLDLDVYENPFGPMPKLLALADRVDKLKAVCFECGEEATISYRLSGEKEQIV
VGDKNYIALCYRCYYAKKKEER

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=181, Percent_Identity=37.5690607734807, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17543396, Length=189, Percent_Identity=33.8624338624339, Blast_Score=109, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21046; Mature: 20914

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRIEVITGPMFSGKSEELVRRALRLMYAKKKVIAFHHALDNRFGHKKIVSRSGFELESY
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCC
PVQNFAFEVIWDLAKDYDAVLVDEAQFFSDELVDTCLNLRRRSKIVVVSGLDLDVYENPF
CHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCCCEEEEECCCEECCCCCC
GPMPKLLALADRVDKLKAVCFECGEEATISYRLSGEKEQIVVGDKNYIALCYRCYYAKKK
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHC
EER
CCC
>Mature Secondary Structure 
GRIEVITGPMFSGKSEELVRRALRLMYAKKKVIAFHHALDNRFGHKKIVSRSGFELESY
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCC
PVQNFAFEVIWDLAKDYDAVLVDEAQFFSDELVDTCLNLRRRSKIVVVSGLDLDVYENPF
CHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCCCEEEEECCCEECCCCCC
GPMPKLLALADRVDKLKAVCFECGEEATISYRLSGEKEQIVVGDKNYIALCYRCYYAKKK
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHC
EER
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA