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The map label for this gene is mog [H]

Identifier: 78042856

GI number: 78042856

Start: 713627

End: 714118

Strand: Direct

Name: mog [H]

Synonym: CHY_0805

Alternate gene names: 78042856

Gene position: 713627-714118 (Clockwise)

Preceding gene: 78044913

Following gene: 78044510

Centisome position: 29.72

GC content: 52.85

Gene sequence:

>492_bases
ATGATTAAAGTGGGCGTTCTTACTTTAAGCGATAAGGGTTCTCGGGGAGAGCGTGAGGATAAAAGCGGCCAGGTAATCAA
GGAAATGGTCCGGGAGATTGATGGGGTGGTGGTGAAGTATGAAGTTATCCCCGATGAGTACGAATTAATTGTTAAAACTT
TAATTTCCTGGTGCGATGAAGAAAAGTTAGATTTAATCCTTACCACCGGTGGCACCGGCTTATCTCCCCGGGATGTGACT
CCAGAAGCTACTAAAGACGTAATTACCCGGGAAGTGCCGGGAATTCCCGAAGCGATGCGCATGGCTTCTCTGGCCAAAAC
CAACCGGGCCATGCTCAGCCGGGCGGTAGCGGGTACCCGGGGTGGCACGTTAATCATCAACCTTCCCGGTAGTCCCAAAG
GAGTGCGGGAAAACCTGGAAGTAGTCTTACCGGTAATCCCCCATGCCCTGGAAATCCTGCAGGCCCGGGGCGGCGAATGC
GGCCAACCCTGA

Upstream 100 bases:

>100_bases
TATCAGGCCGGGGACTGTGTCATGCCCCGGGAAGGTATTTTTGTTAAAGTATTAAAAGGCGGGGAAGTTAAGGTTGGGGA
TCCGGTGGAGGTAATAAGCC

Downstream 100 bases:

>100_bases
ACACCGATTGCAGGGACGGTTCTTTTTTTAGGCGTTTAGACGCAAATATCGGAACCGTCCCTGTTTTTGCTGTTTGGACG
TTTAAAATTGGGACCGGCAT

Product: molybdenum cofactor synthesis domain-containing protein

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MIKVGVLTLSDKGSRGEREDKSGQVIKEMVREIDGVVVKYEVIPDEYELIVKTLISWCDEEKLDLILTTGGTGLSPRDVT
PEATKDVITREVPGIPEAMRMASLAKTNRAMLSRAVAGTRGGTLIINLPGSPKGVRENLEVVLPVIPHALEILQARGGEC
GQP

Sequences:

>Translated_163_residues
MIKVGVLTLSDKGSRGEREDKSGQVIKEMVREIDGVVVKYEVIPDEYELIVKTLISWCDEEKLDLILTTGGTGLSPRDVT
PEATKDVITREVPGIPEAMRMASLAKTNRAMLSRAVAGTRGGTLIINLPGSPKGVRENLEVVLPVIPHALEILQARGGEC
GQP
>Mature_163_residues
MIKVGVLTLSDKGSRGEREDKSGQVIKEMVREIDGVVVKYEVIPDEYELIVKTLISWCDEEKLDLILTTGGTGLSPRDVT
PEATKDVITREVPGIPEAMRMASLAKTNRAMLSRAVAGTRGGTLIINLPGSPKGVRENLEVVLPVIPHALEILQARGGEC
GQP

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=156, Percent_Identity=55.7692307692308, Blast_Score=172, Evalue=1e-43,
Organism=Homo sapiens, GI10880983, Length=156, Percent_Identity=55.7692307692308, Blast_Score=172, Evalue=1e-43,
Organism=Escherichia coli, GI1786190, Length=141, Percent_Identity=42.5531914893617, Blast_Score=104, Evalue=3e-24,
Organism=Escherichia coli, GI1787000, Length=142, Percent_Identity=34.5070422535211, Blast_Score=85, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564954, Length=159, Percent_Identity=43.3962264150943, Blast_Score=115, Evalue=7e-27,
Organism=Drosophila melanogaster, GI17136978, Length=153, Percent_Identity=40.5228758169935, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24638841, Length=153, Percent_Identity=40.5228758169935, Blast_Score=125, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 17600; Mature: 17600

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVGVLTLSDKGSRGEREDKSGQVIKEMVREIDGVVVKYEVIPDEYELIVKTLISWCDE
CEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHCCC
EKLDLILTTGGTGLSPRDVTPEATKDVITREVPGIPEAMRMASLAKTNRAMLSRAVAGTR
CCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GGTLIINLPGSPKGVRENLEVVLPVIPHALEILQARGGECGQP
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIKVGVLTLSDKGSRGEREDKSGQVIKEMVREIDGVVVKYEVIPDEYELIVKTLISWCDE
CEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHCCC
EKLDLILTTGGTGLSPRDVTPEATKDVITREVPGIPEAMRMASLAKTNRAMLSRAVAGTR
CCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GGTLIINLPGSPKGVRENLEVVLPVIPHALEILQARGGECGQP
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]