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The map label for this gene is cobT [H]

Identifier: 78042847

GI number: 78042847

Start: 415512

End: 416573

Strand: Direct

Name: cobT [H]

Synonym: CHY_0480

Alternate gene names: 78042847

Gene position: 415512-416573 (Clockwise)

Preceding gene: 78044716

Following gene: 78045217

Centisome position: 17.3

GC content: 48.49

Gene sequence:

>1062_bases
ATGTTAACGGAAGTTTTAAACCAGATTGGGGATCTTTACCCGGAGCCTATGGTAAAAGCACAAAAGCACTTAGACAGCCT
GATTAAACCGCCGGGAAGCCTTGGAGTCCTGGAGGAAATGGCGGTAAAATTAGCCGGGATTACCGGAGAGCTTGCGCCGA
ATTTAAGCAGGAAAACGGTGGTAGTTATAGCCGGCGACCACGGAATAACCGAACATGGGGTGAGCGTTGCTCCCGTGGAA
GTAACAGCCCAGATGACCCGCTGTTTTCTTGAAGGTATAGCGGGAATTAACGTTTTATCCCGGCATACCGGGGTAGAAGT
TAAGGTTGTAGATATGGGAGTCAGGGCGGAGCTTAACTTACCCGGGCTTATCGTTAAAAAAGTACGTTCCGGTACGTCTG
ACTTTACCCAAGGCCCGGCCATGACCCGGGAGGAAGCCCTACAAGCCATAATGGCCGGGGTAGATGTTGCCCAGGATTTA
ATCGCTCAAGGAAGCAAGGTTTTAATTACCGGGGATATGGGCATCGGCAATACTACACCTTCGGCAGCGATTTTAGCGGT
TTTAATGGATATTCCAGTAGAGCAGGCGGTAGGTCGGGGAACGGGGATTAAAGCTGAAATCTTACAAAAGAAAATAGAGG
TAATCAAAAAAGGGTTAAGGATTAATCAGCCGGATAAAAACGATGCGGTTGATGTCCTTGCTAAAGTTGGCGGTTTTGAA
ATTGGTGGCCTTGCCGGCCTAATATTAGGGGCAGCAGCCCGGAGGGTGCCGGTAGTTATAGATGGGTTTATTTCTTCCGC
GGCGGCAATGTTAGCCGTTTCTCTAAATTCAAAGACTAAAAACTTCCTTTTTCCTTCCCACTTATCCGACGAACCGGGCC
ATAAGCTGATGATGGAATACCTGGGGTTAACCCCTTATCTTCATCTAAAGATGCGCCTTGGGGAAGGAACCGGGGGAGTT
TTTGGAGCCTTTTTCCTGGAAGCCGCTACCAAAGTCATGCGGGAAATGGGAAGTTTTGCATCGAGCGAAGTTTCAGCCTT
ACTGGAAGAAAGAATGGCTTAA

Upstream 100 bases:

>100_bases
TTAGCGGTACGGCGATACCGCTTTAAGCGTGGGTGATGGTAAAGCCCACAGCAGTAGAACTGCTGTGGGCTTTTTAAATT
ATAAAAGGGGGAGATGAACT

Downstream 100 bases:

>100_bases
AAGCAATTATTAAAGAAAAAAGAGGGTGTAAGTTTGGCACCCTCTTTTACTTATTTAAAAGATTTCTTACCGCCTCCCGG
CCGCTTTTAATGCAATCGGG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLTEVLNQIGDLYPEPMVKAQKHLDSLIKPPGSLGVLEEMAVKLAGITGELAPNLSRKTVVVIAGDHGITEHGVSVAPVE
VTAQMTRCFLEGIAGINVLSRHTGVEVKVVDMGVRAELNLPGLIVKKVRSGTSDFTQGPAMTREEALQAIMAGVDVAQDL
IAQGSKVLITGDMGIGNTTPSAAILAVLMDIPVEQAVGRGTGIKAEILQKKIEVIKKGLRINQPDKNDAVDVLAKVGGFE
IGGLAGLILGAAARRVPVVIDGFISSAAAMLAVSLNSKTKNFLFPSHLSDEPGHKLMMEYLGLTPYLHLKMRLGEGTGGV
FGAFFLEAATKVMREMGSFASSEVSALLEERMA

Sequences:

>Translated_353_residues
MLTEVLNQIGDLYPEPMVKAQKHLDSLIKPPGSLGVLEEMAVKLAGITGELAPNLSRKTVVVIAGDHGITEHGVSVAPVE
VTAQMTRCFLEGIAGINVLSRHTGVEVKVVDMGVRAELNLPGLIVKKVRSGTSDFTQGPAMTREEALQAIMAGVDVAQDL
IAQGSKVLITGDMGIGNTTPSAAILAVLMDIPVEQAVGRGTGIKAEILQKKIEVIKKGLRINQPDKNDAVDVLAKVGGFE
IGGLAGLILGAAARRVPVVIDGFISSAAAMLAVSLNSKTKNFLFPSHLSDEPGHKLMMEYLGLTPYLHLKMRLGEGTGGV
FGAFFLEAATKVMREMGSFASSEVSALLEERMA
>Mature_353_residues
MLTEVLNQIGDLYPEPMVKAQKHLDSLIKPPGSLGVLEEMAVKLAGITGELAPNLSRKTVVVIAGDHGITEHGVSVAPVE
VTAQMTRCFLEGIAGINVLSRHTGVEVKVVDMGVRAELNLPGLIVKKVRSGTSDFTQGPAMTREEALQAIMAGVDVAQDL
IAQGSKVLITGDMGIGNTTPSAAILAVLMDIPVEQAVGRGTGIKAEILQKKIEVIKKGLRINQPDKNDAVDVLAKVGGFE
IGGLAGLILGAAARRVPVVIDGFISSAAAMLAVSLNSKTKNFLFPSHLSDEPGHKLMMEYLGLTPYLHLKMRLGEGTGGV
FGAFFLEAATKVMREMGSFASSEVSALLEERMA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=345, Percent_Identity=40, Blast_Score=273, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 37182; Mature: 37182

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTEVLNQIGDLYPEPMVKAQKHLDSLIKPPGSLGVLEEMAVKLAGITGELAPNLSRKTV
CHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCEE
VVIAGDHGITEHGVSVAPVEVTAQMTRCFLEGIAGINVLSRHTGVEVKVVDMGVRAELNL
EEEECCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEECCC
PGLIVKKVRSGTSDFTQGPAMTREEALQAIMAGVDVAQDLIAQGSKVLITGDMGIGNTTP
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCH
SAAILAVLMDIPVEQAVGRGTGIKAEILQKKIEVIKKGLRINQPDKNDAVDVLAKVGGFE
HHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCC
IGGLAGLILGAAARRVPVVIDGFISSAAAMLAVSLNSKTKNFLFPSHLSDEPGHKLMMEY
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
LGLTPYLHLKMRLGEGTGGVFGAFFLEAATKVMREMGSFASSEVSALLEERMA
HCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTEVLNQIGDLYPEPMVKAQKHLDSLIKPPGSLGVLEEMAVKLAGITGELAPNLSRKTV
CHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCEE
VVIAGDHGITEHGVSVAPVEVTAQMTRCFLEGIAGINVLSRHTGVEVKVVDMGVRAELNL
EEEECCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEECCC
PGLIVKKVRSGTSDFTQGPAMTREEALQAIMAGVDVAQDLIAQGSKVLITGDMGIGNTTP
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCH
SAAILAVLMDIPVEQAVGRGTGIKAEILQKKIEVIKKGLRINQPDKNDAVDVLAKVGGFE
HHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCC
IGGLAGLILGAAARRVPVVIDGFISSAAAMLAVSLNSKTKNFLFPSHLSDEPGHKLMMEY
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
LGLTPYLHLKMRLGEGTGGVFGAFFLEAATKVMREMGSFASSEVSALLEERMA
HCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA