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The map label for this gene is htpX [H]

Identifier: 78042762

GI number: 78042762

Start: 93400

End: 94245

Strand: Direct

Name: htpX [H]

Synonym: CHY_0108

Alternate gene names: 78042762

Gene position: 93400-94245 (Clockwise)

Preceding gene: 78043138

Following gene: 78043297

Centisome position: 3.89

GC content: 49.41

Gene sequence:

>846_bases
ATGACCAATACGATAAAAACCTGGCTTTTAATGGGTGTGTTAACAGTTTTGCTGGTTTTACTTGGCAGAGTTATTGGTGG
GACGACCGGAGCATTTACGTTTTTCCTGATAGCTCTGGCCATGAACTTTATTAGCTATTACTTCAGCGATACCCTGGTAA
TAAAAATGACCGGTTCTTATCCGGTAAGTGAGGCGGAGGCGCCGGAGTTGTACTCAATTGTGAGAAATCTATCCTTAAAA
GCCGGCATTCCCATGCCCAAAATTTATATTACCCCGTCGCCCCAGCCCAATGCTTTTGCCACCGGGCGTAATCCTGAACA
CGCAGCGGTAGCGGTAACCGAAGGACTTTTAAATCTTCTAAACCGGCAGGAGATTGAAGGGGTGCTGGCCCACGAGATAG
CTCATATTAAAAACCGGGATATTCTGATAGGAACCATTGCGGCGGCTATGGCCGGAGCTATTTCCATGCTGGCGGATGTT
TTTCGCTGGGGGTTGTTTTTTGGCGGTGGTCGCGATGATGATAATAATCCCGGAGGGCTTATAGCCGATCTTATCCTGCT
GATTTTAGCTCCGATTGCGGCTTTACTGGTGCAGCTTGCGATTTCCCGTTCCCGGGAGTATTTGGCCGATGAAACGGGGG
CAAAGCTTGCGGGGTCACCGGTGGGCCTTGCGGAGGCTTTAAAGAAGCTCCATGCTTACAGCTTGCGGATACCGATGGAA
GTGTCTCCAGCCGCATCGCATATGTTTATCATAAACCCCTTGAACGGACGGGCCTTAATGGCGCTTTTCTCTACCCATCC
ACCCATTGAAGACCGGATTGAAAGGCTTTATGCTATGAGGTGGTAG

Upstream 100 bases:

>100_bases
AACTCCAGCATTTTACTACTTCCCGTTGGTATCAAACGTCTTATTTTGATGGATTTGGCGTAGCTTAAAAGGATTAACAA
ATTTAAGGGGGAAGAGAAGA

Downstream 100 bases:

>100_bases
TTTAAAATTGCAGGTACGGTTTCCAACCGTACCTGCATTTAATTTTATTCCTGACTGTGAAAGAAGGAGAATTTTCAAAC
AACAAGGGGAAAACAGGATT

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTNTIKTWLLMGVLTVLLVLLGRVIGGTTGAFTFFLIALAMNFISYYFSDTLVIKMTGSYPVSEAEAPELYSIVRNLSLK
AGIPMPKIYITPSPQPNAFATGRNPEHAAVAVTEGLLNLLNRQEIEGVLAHEIAHIKNRDILIGTIAAAMAGAISMLADV
FRWGLFFGGGRDDDNNPGGLIADLILLILAPIAALLVQLAISRSREYLADETGAKLAGSPVGLAEALKKLHAYSLRIPME
VSPAASHMFIINPLNGRALMALFSTHPPIEDRIERLYAMRW

Sequences:

>Translated_281_residues
MTNTIKTWLLMGVLTVLLVLLGRVIGGTTGAFTFFLIALAMNFISYYFSDTLVIKMTGSYPVSEAEAPELYSIVRNLSLK
AGIPMPKIYITPSPQPNAFATGRNPEHAAVAVTEGLLNLLNRQEIEGVLAHEIAHIKNRDILIGTIAAAMAGAISMLADV
FRWGLFFGGGRDDDNNPGGLIADLILLILAPIAALLVQLAISRSREYLADETGAKLAGSPVGLAEALKKLHAYSLRIPME
VSPAASHMFIINPLNGRALMALFSTHPPIEDRIERLYAMRW
>Mature_280_residues
TNTIKTWLLMGVLTVLLVLLGRVIGGTTGAFTFFLIALAMNFISYYFSDTLVIKMTGSYPVSEAEAPELYSIVRNLSLKA
GIPMPKIYITPSPQPNAFATGRNPEHAAVAVTEGLLNLLNRQEIEGVLAHEIAHIKNRDILIGTIAAAMAGAISMLADVF
RWGLFFGGGRDDDNNPGGLIADLILLILAPIAALLVQLAISRSREYLADETGAKLAGSPVGLAEALKKLHAYSLRIPMEV
SPAASHMFIINPLNGRALMALFSTHPPIEDRIERLYAMRW

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=255, Percent_Identity=31.3725490196078, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 30439; Mature: 30308

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTIKTWLLMGVLTVLLVLLGRVIGGTTGAFTFFLIALAMNFISYYFSDTLVIKMTGSY
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
PVSEAEAPELYSIVRNLSLKAGIPMPKIYITPSPQPNAFATGRNPEHAAVAVTEGLLNLL
CCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHH
NRQEIEGVLAHEIAHIKNRDILIGTIAAAMAGAISMLADVFRWGLFFGGGRDDDNNPGGL
HHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
IADLILLILAPIAALLVQLAISRSREYLADETGAKLAGSPVGLAEALKKLHAYSLRIPME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
VSPAASHMFIINPLNGRALMALFSTHPPIEDRIERLYAMRW
ECCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TNTIKTWLLMGVLTVLLVLLGRVIGGTTGAFTFFLIALAMNFISYYFSDTLVIKMTGSY
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
PVSEAEAPELYSIVRNLSLKAGIPMPKIYITPSPQPNAFATGRNPEHAAVAVTEGLLNLL
CCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHH
NRQEIEGVLAHEIAHIKNRDILIGTIAAAMAGAISMLADVFRWGLFFGGGRDDDNNPGGL
HHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
IADLILLILAPIAALLVQLAISRSREYLADETGAKLAGSPVGLAEALKKLHAYSLRIPME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
VSPAASHMFIINPLNGRALMALFSTHPPIEDRIERLYAMRW
ECCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA