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The map label for this gene is yhcK [H]

Identifier: 78042726

GI number: 78042726

Start: 121602

End: 123233

Strand: Direct

Name: yhcK [H]

Synonym: CHY_0140

Alternate gene names: 78042726

Gene position: 121602-123233 (Clockwise)

Preceding gene: 78043220

Following gene: 78044784

Centisome position: 5.06

GC content: 40.5

Gene sequence:

>1632_bases
ATGGCAGGAAAAACCAAAAAATTGTCGAAAAATTACAGCATGCACAAGGTTAATTATTGGCAGATTTGGCGGGTAATAGT
TTCATTAGCGGGATTTATTCTAACGGTATTTTACCTTTTAAAAGGCAGCATTCAGCCGCCGGGGGCTTTTTTTGCCCTTC
TTACGGTTAGTTTTATTTTAGAACTTACCGCCATAGAGATTTGTGGTTCCAAAATTAAGGGGTCTTATGTTTTTTACCTG
GTTACCCTGCTACTAAAGGGAAAAGGTTTTGCTGTAGTATTAAGTTTTCTTGCAGGATTATTAGCTTCCTTTTTAACTAA
AGAGGAAAAAACTTTTCCGGGATATTTTTTTGAAGGAGCAAAAAACAGCCTGGGCATTTTACTGGGAAGTCATTTGGCCG
GGTACCTACCCGGAGGAGAGTTTTTTCTTGCGCTAATCTATACCGCAGGTTTTATTCTGGTTGATGCAGTTTTTATGATT
TTAAGAGCTTTCTTTGGAGAAAATGCGGGGTCCACTAAAGAAGAAATTTTTTATTACGGTTTAAACTGTTTTCTCACCTT
TACCGCTGGAGTATTGCTTACCGAGGCAATTAAGAAAAATTTCTATCAAGCACTTTTTCTTGGACTTTTACTTACCGAAG
CTTTTTATCTGGTGATAAAAATAAACCAAAAGCTTTTAAACCAAAGCCTCGACTACGTAACTTTGTGGAATATTTCCCGA
ACCTTTCACCGCCTGGAAACTCCCGATGATATGTTAAAAGCAATGTTACAGGAATTAAAAAATACTTTTTCCTACCATAC
CGGGGTCATTTATACTTATTCCGAATCCCTGAGAAAATATATTCCCCGCTATTTAAACACCGATTTTCCCGAACTTCCGG
GACCGGAGTTTCATAATACCCTGCTTTCCGAGATGGGAAATAGAAAAACTGCTGCTTTAATAAAACACCCGCAATTAGGG
AGTATTGCGGTGGTACCGTTGCAAAACCGCAGGGATGTCTTTGGTTACCTGGTAATAGTGGCCCCAAAAGGGCAGAACTA
TTCCCATAGTCAGCTCAGGCGTCTTGAAAATATTTCGGGACAGGTGGCCCTGGCGGTTTATAACGGCTACTTGTATTTAC
GTTTAAAGGAGCTTGCCCAGAAAGATGAGTTAACCGGCTTATATAACCGGCGTTACTTCTTGGAAAGGCTTAATGAGGAG
CATTTACGTTCCCGCAGGCATAAATTAAATTACACCATTGTTCTTTTAGATATAGATTATTTTAAAAAGATAAACGATAC
TTACGGTCACGACTGTGGAGATTTGGTTTTAAACGATTTTGGGCGGTTTTTAAAAGATACCCTCCGGCGGACCGATTTAA
GTGCCCGCTACGGTGGGGAGGAGTTTGTTGTTTTGCTACCCCAGACCGGGAAAAAGGAAGCCTATCTCTTAGCGGAACGC
TTGCGGGAGAAAGTTAAAGAGCGGGTTTTAATTTTTCAAGGGCAAAAGGTCAAATATACCGTTAGCATGGGACTGGCTGC
TTATCCGGAGGATGCTGAAGAGTATCGGGAACTGTTAAGCTTAGCCGATAAAGCTTTGTATCAAGCGAAAAACCGGGGCA
GGGATAAAGTGGTAATGGTAAATAATTTTTAG

Upstream 100 bases:

>100_bases
TAGATTTAACCGGTACGCTAATTTCTTCGCGTTTTCAGGTAATTAACGGGCTTCCGGAGGAAATTCAGAGGGAAAACTAT
ATTATCTTTTTTTAAAATAT

Downstream 100 bases:

>100_bases
GGATTAAGTATAATTATTTAAAAATTTGGCAATATTACTACCGTAAAATAAAAAAATGGAGGTAGTAATATGCTGAGTTT
ACTGGAAAAAACAAGACTCT

Product: GGDEF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MAGKTKKLSKNYSMHKVNYWQIWRVIVSLAGFILTVFYLLKGSIQPPGAFFALLTVSFILELTAIEICGSKIKGSYVFYL
VTLLLKGKGFAVVLSFLAGLLASFLTKEEKTFPGYFFEGAKNSLGILLGSHLAGYLPGGEFFLALIYTAGFILVDAVFMI
LRAFFGENAGSTKEEIFYYGLNCFLTFTAGVLLTEAIKKNFYQALFLGLLLTEAFYLVIKINQKLLNQSLDYVTLWNISR
TFHRLETPDDMLKAMLQELKNTFSYHTGVIYTYSESLRKYIPRYLNTDFPELPGPEFHNTLLSEMGNRKTAALIKHPQLG
SIAVVPLQNRRDVFGYLVIVAPKGQNYSHSQLRRLENISGQVALAVYNGYLYLRLKELAQKDELTGLYNRRYFLERLNEE
HLRSRRHKLNYTIVLLDIDYFKKINDTYGHDCGDLVLNDFGRFLKDTLRRTDLSARYGGEEFVVLLPQTGKKEAYLLAER
LREKVKERVLIFQGQKVKYTVSMGLAAYPEDAEEYRELLSLADKALYQAKNRGRDKVVMVNNF

Sequences:

>Translated_543_residues
MAGKTKKLSKNYSMHKVNYWQIWRVIVSLAGFILTVFYLLKGSIQPPGAFFALLTVSFILELTAIEICGSKIKGSYVFYL
VTLLLKGKGFAVVLSFLAGLLASFLTKEEKTFPGYFFEGAKNSLGILLGSHLAGYLPGGEFFLALIYTAGFILVDAVFMI
LRAFFGENAGSTKEEIFYYGLNCFLTFTAGVLLTEAIKKNFYQALFLGLLLTEAFYLVIKINQKLLNQSLDYVTLWNISR
TFHRLETPDDMLKAMLQELKNTFSYHTGVIYTYSESLRKYIPRYLNTDFPELPGPEFHNTLLSEMGNRKTAALIKHPQLG
SIAVVPLQNRRDVFGYLVIVAPKGQNYSHSQLRRLENISGQVALAVYNGYLYLRLKELAQKDELTGLYNRRYFLERLNEE
HLRSRRHKLNYTIVLLDIDYFKKINDTYGHDCGDLVLNDFGRFLKDTLRRTDLSARYGGEEFVVLLPQTGKKEAYLLAER
LREKVKERVLIFQGQKVKYTVSMGLAAYPEDAEEYRELLSLADKALYQAKNRGRDKVVMVNNF
>Mature_542_residues
AGKTKKLSKNYSMHKVNYWQIWRVIVSLAGFILTVFYLLKGSIQPPGAFFALLTVSFILELTAIEICGSKIKGSYVFYLV
TLLLKGKGFAVVLSFLAGLLASFLTKEEKTFPGYFFEGAKNSLGILLGSHLAGYLPGGEFFLALIYTAGFILVDAVFMIL
RAFFGENAGSTKEEIFYYGLNCFLTFTAGVLLTEAIKKNFYQALFLGLLLTEAFYLVIKINQKLLNQSLDYVTLWNISRT
FHRLETPDDMLKAMLQELKNTFSYHTGVIYTYSESLRKYIPRYLNTDFPELPGPEFHNTLLSEMGNRKTAALIKHPQLGS
IAVVPLQNRRDVFGYLVIVAPKGQNYSHSQLRRLENISGQVALAVYNGYLYLRLKELAQKDELTGLYNRRYFLERLNEEH
LRSRRHKLNYTIVLLDIDYFKKINDTYGHDCGDLVLNDFGRFLKDTLRRTDLSARYGGEEFVVLLPQTGKKEAYLLAERL
REKVKERVLIFQGQKVKYTVSMGLAAYPEDAEEYRELLSLADKALYQAKNRGRDKVVMVNNF

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=196, Percent_Identity=37.2448979591837, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI1786584, Length=163, Percent_Identity=39.2638036809816, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=38.2716049382716, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082007, Length=170, Percent_Identity=36.4705882352941, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI87081881, Length=165, Percent_Identity=40.6060606060606, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=35.6687898089172, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788085, Length=204, Percent_Identity=32.843137254902, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1788381, Length=168, Percent_Identity=33.9285714285714, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1787816, Length=185, Percent_Identity=34.0540540540541, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787541, Length=169, Percent_Identity=33.1360946745562, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081977, Length=206, Percent_Identity=28.6407766990291, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081974, Length=116, Percent_Identity=30.1724137931034, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788956, Length=166, Percent_Identity=33.1325301204819, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787056, Length=157, Percent_Identity=31.8471337579618, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 62103; Mature: 61972

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKTKKLSKNYSMHKVNYWQIWRVIVSLAGFILTVFYLLKGSIQPPGAFFALLTVSFIL
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ELTAIEICGSKIKGSYVFYLVTLLLKGKGFAVVLSFLAGLLASFLTKEEKTFPGYFFEGA
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCC
KNSLGILLGSHLAGYLPGGEFFLALIYTAGFILVDAVFMILRAFFGENAGSTKEEIFYYG
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LNCFLTFTAGVLLTEAIKKNFYQALFLGLLLTEAFYLVIKINQKLLNQSLDYVTLWNISR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHCCCCCEEEEECHHH
TFHRLETPDDMLKAMLQELKNTFSYHTGVIYTYSESLRKYIPRYLNTDFPELPGPEFHNT
HHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHCCCCCCCCCCHHHHH
LLSEMGNRKTAALIKHPQLGSIAVVPLQNRRDVFGYLVIVAPKGQNYSHSQLRRLENISG
HHHHCCCCCHHHHCCCCCCCCEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHCCCC
QVALAVYNGYLYLRLKELAQKDELTGLYNRRYFLERLNEEHLRSRRHKLNYTIVLLDIDY
CEEEEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEEEHHH
FKKINDTYGHDCGDLVLNDFGRFLKDTLRRTDLSARYGGEEFVVLLPQTGKKEAYLLAER
HHHHCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
LREKVKERVLIFQGQKVKYTVSMGLAAYPEDAEEYRELLSLADKALYQAKNRGRDKVVMV
HHHHHHHHEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
NNF
ECC
>Mature Secondary Structure 
AGKTKKLSKNYSMHKVNYWQIWRVIVSLAGFILTVFYLLKGSIQPPGAFFALLTVSFIL
CCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ELTAIEICGSKIKGSYVFYLVTLLLKGKGFAVVLSFLAGLLASFLTKEEKTFPGYFFEGA
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCC
KNSLGILLGSHLAGYLPGGEFFLALIYTAGFILVDAVFMILRAFFGENAGSTKEEIFYYG
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LNCFLTFTAGVLLTEAIKKNFYQALFLGLLLTEAFYLVIKINQKLLNQSLDYVTLWNISR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHCCCCCEEEEECHHH
TFHRLETPDDMLKAMLQELKNTFSYHTGVIYTYSESLRKYIPRYLNTDFPELPGPEFHNT
HHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHCCCCCCCCCCHHHHH
LLSEMGNRKTAALIKHPQLGSIAVVPLQNRRDVFGYLVIVAPKGQNYSHSQLRRLENISG
HHHHCCCCCHHHHCCCCCCCCEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHCCCC
QVALAVYNGYLYLRLKELAQKDELTGLYNRRYFLERLNEEHLRSRRHKLNYTIVLLDIDY
CEEEEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEEEHHH
FKKINDTYGHDCGDLVLNDFGRFLKDTLRRTDLSARYGGEEFVVLLPQTGKKEAYLLAER
HHHHCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
LREKVKERVLIFQGQKVKYTVSMGLAAYPEDAEEYRELLSLADKALYQAKNRGRDKVVMV
HHHHHHHHEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
NNF
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]