Click here to switch to the map view.

The map label for this gene is yqgN [H]

Identifier: 78042640

GI number: 78042640

Start: 643123

End: 643701

Strand: Direct

Name: yqgN [H]

Synonym: CHY_0730

Alternate gene names: 78042640

Gene position: 643123-643701 (Clockwise)

Preceding gene: 78042649

Following gene: 78044572

Centisome position: 26.78

GC content: 43.7

Gene sequence:

>579_bases
ATGGATGATAAAAAAGTATTGAGAAAGGAAATATTAAACAAAAGAGCCGCCCAAACTCCCGCTGAAATAGCTGCAAAAAG
TTCCAGAATTTTAACACTTTTAAAAGCCTTTGCGCCCTATCAACAGGCGCGGACGGTAATGGTTTACCTGGATTTTCGCG
GGGAGGTTAAAACCCGGGAAATTATCAGGGACTTATGGGCTTACGGTAAAAAAGTGGTAATACCGGTGACAGTTCTTTCG
GAAAAAAAGCTTTTACCGGTTTACCTTAGAGATTTTGGGGACCTGGTAGAAGGAACTTACGGAATCCTGGAGCCTAAAGA
GGAAGCAAGAACGATTGCGGAACCGGAAGTAATTGATTTGGTCCTGGTACCGGGAGTAGCTTTTGATTTAAAGGGAAACC
GCCTGGGATACGGAGCCGGTTTTTACGACCGATTTTTACCCAATCTTCAGCCCGCGGTAAAAAAGGTGGCTTTAGCCTTC
GAACTACAAATAGTACCCAAAATTCCAACCGGACCCCACGATATCCCAATGGATTATATCATAACCGAAGAGCGCATTAT
AAACTGCCGCCTTTATTAA

Upstream 100 bases:

>100_bases
TTTTAAAAATGATTAAAAATAGCAGGAATATTAACGAATAAAGAGAATACTTAAACAGTTAGTCTATTTTTGAAAAATCT
GAAAATAAGGAAGATCATGG

Downstream 100 bases:

>100_bases
AAAGTTTATAAAGGTTTATTTATTAATGTTTTCTCCAACTTCTAACATCTAACTTCCAATATCTAAGTTGTTTTTATCAA
AAGGTTATAAAAGGTTATTA

Product: 5-formyltetrahydrofolate cyclo-ligase family protein

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MDDKKVLRKEILNKRAAQTPAEIAAKSSRILTLLKAFAPYQQARTVMVYLDFRGEVKTREIIRDLWAYGKKVVIPVTVLS
EKKLLPVYLRDFGDLVEGTYGILEPKEEARTIAEPEVIDLVLVPGVAFDLKGNRLGYGAGFYDRFLPNLQPAVKKVALAF
ELQIVPKIPTGPHDIPMDYIITEERIINCRLY

Sequences:

>Translated_192_residues
MDDKKVLRKEILNKRAAQTPAEIAAKSSRILTLLKAFAPYQQARTVMVYLDFRGEVKTREIIRDLWAYGKKVVIPVTVLS
EKKLLPVYLRDFGDLVEGTYGILEPKEEARTIAEPEVIDLVLVPGVAFDLKGNRLGYGAGFYDRFLPNLQPAVKKVALAF
ELQIVPKIPTGPHDIPMDYIITEERIINCRLY
>Mature_192_residues
MDDKKVLRKEILNKRAAQTPAEIAAKSSRILTLLKAFAPYQQARTVMVYLDFRGEVKTREIIRDLWAYGKKVVIPVTVLS
EKKLLPVYLRDFGDLVEGTYGILEPKEEARTIAEPEVIDLVLVPGVAFDLKGNRLGYGAGFYDRFLPNLQPAVKKVALAF
ELQIVPKIPTGPHDIPMDYIITEERIINCRLY

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=194, Percent_Identity=31.4432989690722, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1789278, Length=178, Percent_Identity=35.3932584269663, Blast_Score=102, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17510857, Length=158, Percent_Identity=33.5443037974684, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321031, Length=211, Percent_Identity=32.7014218009479, Blast_Score=88, Evalue=7e-19,
Organism=Drosophila melanogaster, GI161077430, Length=191, Percent_Identity=28.2722513089005, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 21773; Mature: 21773

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDKKVLRKEILNKRAAQTPAEIAAKSSRILTLLKAFAPYQQARTVMVYLDFRGEVKTRE
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEEECCCCCHHHH
IIRDLWAYGKKVVIPVTVLSEKKLLPVYLRDFGDLVEGTYGILEPKEEARTIAEPEVIDL
HHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEE
VLVPGVAFDLKGNRLGYGAGFYDRFLPNLQPAVKKVALAFELQIVPKIPTGPHDIPMDYI
EEECCEEEEECCCEEECCCCHHHHHCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCEE
ITEERIINCRLY
EECCEEEEEECC
>Mature Secondary Structure
MDDKKVLRKEILNKRAAQTPAEIAAKSSRILTLLKAFAPYQQARTVMVYLDFRGEVKTRE
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEEECCCCCHHHH
IIRDLWAYGKKVVIPVTVLSEKKLLPVYLRDFGDLVEGTYGILEPKEEARTIAEPEVIDL
HHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEE
VLVPGVAFDLKGNRLGYGAGFYDRFLPNLQPAVKKVALAFELQIVPKIPTGPHDIPMDYI
EEECCEEEEECCCEEECCCCHHHHHCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCEE
ITEERIINCRLY
EECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]