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The map label for this gene is rbsK [H]

Identifier: 77465700

GI number: 77465700

Start: 813339

End: 814217

Strand: Reverse

Name: rbsK [H]

Synonym: RSP_3692

Alternate gene names: 77465700

Gene position: 814217-813339 (Counterclockwise)

Preceding gene: 77465703

Following gene: 77465689

Centisome position: 86.34

GC content: 73.15

Gene sequence:

>879_bases
ATGAAGGTCTTCGTCATCGGCAACGTGGCGCTCGACGAGACGCTTTCGATCGAGGACTTTCCCCGTCCGGGGGCCTCGAT
CTTCGGGGCGGCGCTGTCGCGCGACCTCGGGGGGAAGGGGGCCAACCAGGCGGTGGCGATGGGGCGGACGGGGCTTGCCT
GCATCTTCGTCTCGGCCGTGGGGCAGGGGCCGCGCGGACAGGAGATCGCGCAGCGTCTGGCCCAGGAGCCGCTCGAGGCG
GAGCTCGTGGCGCTGGAGGGCGTGGCCACGGATATCTCGATCGTGCTCATGTCGGCACGGGGCGAGAATGCGATCATCAC
CACGCGCGAGGCGGCCTCGGCGCTGACGCCGGAGGCGGCGGCCGCGGCGCTGGCCCGCGGCCAGACCGGGGACCTTCTGG
TGCTGCAGGGCAATCTGAGTGCGGCGGCCACGCAGGCGGCGCTGCGCGCTGCGCGAGACGCGGGGATGCGCACGGCCTTC
AACCCCTCGCCGCTCCAGCCGTATTTCGGCACGCTCTGGCCTCTGGTCGACACGGTGTTCCTCAATGAAGGCGAAGCCGA
GGCGCTCGGCGGGGTGGAGAGCCTGCTGGCGCAGGGGGTGGGCGAGATCGTCCTCACGCTGGGCGCGCAGGGGGCCGAGC
TGATCCGTACGACCGAGCGGACGCGGGTGCCCGCCCATCCCTGCGCCGTGGTGGACACGACCGGGGCCGGGGACTGTTTC
ATGGCGGTGGCGCTGGCCTCGGCCGCGCTGCGCGGCACGCGGCTCGATGCACGCGCGCTGAACCATGCGGCACGGGCGGC
GGCCCACACGGTCGGGCGCGCGGGCACCGTGGCGGCCTTTCCGAACCGGGCCGAGATGGCCGCGATCCTCGCCACCTGA

Upstream 100 bases:

>100_bases
ATCAGGGCCTTGTCACGACCGAAGATCTCGTGGATCGCGCCGGAGGTTCTGTCGGAGATGAGCTGCATATCATGACCTTT
CGGAAGAGAAGGAACGCGGG

Downstream 100 bases:

>100_bases
GGGCAGGGGCCCGACCCGCTCGCCCGGAAGGACGCGCGGGCCGGACCCGCCGGCTGGGGAGCGACAGCCGGCCCTGCGGC
CCGGAACGGCCGGCCCCTGC

Product: carbohydrate kinase, PfkB/ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKVFVIGNVALDETLSIEDFPRPGASIFGAALSRDLGGKGANQAVAMGRTGLACIFVSAVGQGPRGQEIAQRLAQEPLEA
ELVALEGVATDISIVLMSARGENAIITTREAASALTPEAAAAALARGQTGDLLVLQGNLSAAATQAALRAARDAGMRTAF
NPSPLQPYFGTLWPLVDTVFLNEGEAEALGGVESLLAQGVGEIVLTLGAQGAELIRTTERTRVPAHPCAVVDTTGAGDCF
MAVALASAALRGTRLDARALNHAARAAAHTVGRAGTVAAFPNRAEMAAILAT

Sequences:

>Translated_292_residues
MKVFVIGNVALDETLSIEDFPRPGASIFGAALSRDLGGKGANQAVAMGRTGLACIFVSAVGQGPRGQEIAQRLAQEPLEA
ELVALEGVATDISIVLMSARGENAIITTREAASALTPEAAAAALARGQTGDLLVLQGNLSAAATQAALRAARDAGMRTAF
NPSPLQPYFGTLWPLVDTVFLNEGEAEALGGVESLLAQGVGEIVLTLGAQGAELIRTTERTRVPAHPCAVVDTTGAGDCF
MAVALASAALRGTRLDARALNHAARAAAHTVGRAGTVAAFPNRAEMAAILAT
>Mature_292_residues
MKVFVIGNVALDETLSIEDFPRPGASIFGAALSRDLGGKGANQAVAMGRTGLACIFVSAVGQGPRGQEIAQRLAQEPLEA
ELVALEGVATDISIVLMSARGENAIITTREAASALTPEAAAAALARGQTGDLLVLQGNLSAAATQAALRAARDAGMRTAF
NPSPLQPYFGTLWPLVDTVFLNEGEAEALGGVESLLAQGVGEIVLTLGAQGAELIRTTERTRVPAHPCAVVDTTGAGDCF
MAVALASAALRGTRLDARALNHAARAAAHTVGRAGTVAAFPNRAEMAAILAT

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=294, Percent_Identity=31.2925170068027, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1790193, Length=301, Percent_Identity=31.8936877076412, Blast_Score=116, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17532905, Length=303, Percent_Identity=30.6930693069307, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24583886, Length=303, Percent_Identity=26.4026402640264, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20128807, Length=303, Percent_Identity=29.042904290429, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 29732; Mature: 29732

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVFVIGNVALDETLSIEDFPRPGASIFGAALSRDLGGKGANQAVAMGRTGLACIFVSAV
CEEEEEECEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHEEHH
GQGPRGQEIAQRLAQEPLEAELVALEGVATDISIVLMSARGENAIITTREAASALTPEAA
CCCCCHHHHHHHHHHCCHHHHHEEHHCCCCCEEEEEEECCCCCEEEEEHHHHHHCCHHHH
AAALARGQTGDLLVLQGNLSAAATQAALRAARDAGMRTAFNPSPLQPYFGTLWPLVDTVF
HHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
LNEGEAEALGGVESLLAQGVGEIVLTLGAQGAELIRTTERTRVPAHPCAVVDTTGAGDCF
CCCCCHHHHHHHHHHHHHCHHHEEHECCCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHH
MAVALASAALRGTRLDARALNHAARAAAHTVGRAGTVAAFPNRAEMAAILAT
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHEEEECC
>Mature Secondary Structure
MKVFVIGNVALDETLSIEDFPRPGASIFGAALSRDLGGKGANQAVAMGRTGLACIFVSAV
CEEEEEECEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHEEHH
GQGPRGQEIAQRLAQEPLEAELVALEGVATDISIVLMSARGENAIITTREAASALTPEAA
CCCCCHHHHHHHHHHCCHHHHHEEHHCCCCCEEEEEEECCCCCEEEEEHHHHHHCCHHHH
AAALARGQTGDLLVLQGNLSAAATQAALRAARDAGMRTAFNPSPLQPYFGTLWPLVDTVF
HHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
LNEGEAEALGGVESLLAQGVGEIVLTLGAQGAELIRTTERTRVPAHPCAVVDTTGAGDCF
CCCCCHHHHHHHHHHHHHCHHHEEHECCCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHH
MAVALASAALRGTRLDARALNHAARAAAHTVGRAGTVAAFPNRAEMAAILAT
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]