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The map label for this gene is exsB [H]

Identifier: 77465652

GI number: 77465652

Start: 750218

End: 750841

Strand: Direct

Name: exsB [H]

Synonym: RSP_3642

Alternate gene names: 77465652

Gene position: 750218-750841 (Clockwise)

Preceding gene: 77465651

Following gene: 77465653

Centisome position: 79.56

GC content: 52.4

Gene sequence:

>624_bases
ATGAGCTTCGCGCTATTAATGGCATCTGGCGGGTTGGACTCGACAACAGTTGCATACTGGCTCACCGAAAGGGGGGTACA
ATTTATTCCGGTCTTCTTCGACTACGGGCAGCACTGCGTGGAGACCGAGTGGGAAACACTTAAGGAGGTACTGCCAGCAT
CGGCTGCACATCCAGAAAGAAATGATATCTCCGACCTTTTTAGGGGATCGAAGTCAAGGTTGATAACAGAGGCTGACCTT
TGGAATGAAGAGGTGAAGGATGAAGATCTTTACGTGCCTTACCGAACTCTTCTATTCTATTCTGCAGCTGCGGCACGTGC
CCAGACACTGGGAGCGTTTGAGGTTTACACCGGCTTTATCAACAGCAACCGCGCTAAGGAGATCGACTGTACGGCCGAGT
TCATGAACAAGCTCGACGCGCTTACTGACTCGGTTGGTCCAGTCCGGTTCTTGTCACCGTTTCGCTTCTGGTCCAAGTCA
GAAGTCGCAAAGGAATCTATTCGACTGGGAGTTCCAATTGGGCGCACCTTCTCCTGCCAAGCTGCGAGCCTGATGCCTTG
TGGCGCTTGCCCTAACTGCGTCGAACGTCTAGCAGCGCTTCGAGAAACAGGGTTACTGGCATGA

Upstream 100 bases:

>100_bases
ATACGATGGTGATCTGCGGCAGCGACGCCTACTCAGATGACTTGGACCAGTGCTTGAACTCGACGTTCGAACTTCTCGCC
AAACTGCGGGAGCAAGCGAA

Downstream 100 bases:

>100_bases
GCTCGATGGCTATAGACAACGACGCGGTGGAAATTCTCATTGCTGCACGGCGGGTTGCAAACTTTGCGTGTCTCCAGGGC
GTCCCTGCCGATTCGCGCCA

Product: putative ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSFALLMASGGLDSTTVAYWLTERGVQFIPVFFDYGQHCVETEWETLKEVLPASAAHPERNDISDLFRGSKSRLITEADL
WNEEVKDEDLYVPYRTLLFYSAAAARAQTLGAFEVYTGFINSNRAKEIDCTAEFMNKLDALTDSVGPVRFLSPFRFWSKS
EVAKESIRLGVPIGRTFSCQAASLMPCGACPNCVERLAALRETGLLA

Sequences:

>Translated_207_residues
MSFALLMASGGLDSTTVAYWLTERGVQFIPVFFDYGQHCVETEWETLKEVLPASAAHPERNDISDLFRGSKSRLITEADL
WNEEVKDEDLYVPYRTLLFYSAAAARAQTLGAFEVYTGFINSNRAKEIDCTAEFMNKLDALTDSVGPVRFLSPFRFWSKS
EVAKESIRLGVPIGRTFSCQAASLMPCGACPNCVERLAALRETGLLA
>Mature_206_residues
SFALLMASGGLDSTTVAYWLTERGVQFIPVFFDYGQHCVETEWETLKEVLPASAAHPERNDISDLFRGSKSRLITEADLW
NEEVKDEDLYVPYRTLLFYSAAAARAQTLGAFEVYTGFINSNRAKEIDCTAEFMNKLDALTDSVGPVRFLSPFRFWSKSE
VAKESIRLGVPIGRTFSCQAASLMPCGACPNCVERLAALRETGLLA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 23015; Mature: 22884

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFALLMASGGLDSTTVAYWLTERGVQFIPVFFDYGQHCVETEWETLKEVLPASAAHPER
CCEEEEEECCCCCCHHHHHHHHHCCCEEEHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCC
NDISDLFRGSKSRLITEADLWNEEVKDEDLYVPYRTLLFYSAAAARAQTLGAFEVYTGFI
CCHHHHHCCCHHHEEEHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
NSNRAKEIDCTAEFMNKLDALTDSVGPVRFLSPFRFWSKSEVAKESIRLGVPIGRTFSCQ
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCC
AASLMPCGACPNCVERLAALRETGLLA
CCCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFALLMASGGLDSTTVAYWLTERGVQFIPVFFDYGQHCVETEWETLKEVLPASAAHPER
CEEEEEECCCCCCHHHHHHHHHCCCEEEHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCC
NDISDLFRGSKSRLITEADLWNEEVKDEDLYVPYRTLLFYSAAAARAQTLGAFEVYTGFI
CCHHHHHCCCHHHEEEHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
NSNRAKEIDCTAEFMNKLDALTDSVGPVRFLSPFRFWSKSEVAKESIRLGVPIGRTFSCQ
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCC
AASLMPCGACPNCVERLAALRETGLLA
CCCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA