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The map label for this gene is lsrR [H]

Identifier: 77465506

GI number: 77465506

Start: 583851

End: 584789

Strand: Direct

Name: lsrR [H]

Synonym: RSP_3505

Alternate gene names: 77465506

Gene position: 583851-584789 (Clockwise)

Preceding gene: 77465500

Following gene: 77465507

Centisome position: 61.91

GC content: 68.8

Gene sequence:

>939_bases
ATGGCGGAACAGACCCGGAGCGACTTCGACGAAGCGCTCATGGCACGCGTGGCCTGGCTCTATTACAACGACGGGCTGAC
CCAGAACGAGGTGGGCGAGATCCTCAACATCTCGCGCATCAAGGTCTCGCGGCTGCTCGATCAGGGGCGCAGCTCGGGCC
TGATCCAGGTGCGGATCAACTCGCGTCAGCAGGGCTGTCTCGAGCTCGAGACCCGGATGAAGCGGGAATTCGGGCTAACC
GACTGCCGGGTGATTCCCGAGAGCCCGGTGGAGGATGTGAACCTGCGCGTGGGTCAGGCGGCCGCGCAGTATCTCATGCA
GAAGCTCGCCTTCGGCGAGACGATCTCGGTCGGCTGGGGCGAGACGGTGACCCACTCGATCCGGATGCTGGGCCACACCG
CGCAGGAGCGCAGCATCGGGCTCTATTCCCTCACCGGCGGCGTGCAGACCTATGTCGAAGGGATGCGCGAGGCCAACTGG
CATCGCAATGTGAACATCATCCCCGCCCCGCTCGTGGTCTCGACCCCCGAGCTTGCCCGCGCGCTGATGCAGGAGCCCGC
GATCGCGGCGCTCATGGCCCGCGCGCTCGAGGCCGACTACAAGCTGGTGGGGATCGGCGGCCTCGGCGAAAGCGCCACCG
TGGTCACGCAGGGCTATATCTCGGCGGGCGAGATCGACCCGCTGCGACGCGGCGGGGCGCGCGGCGACATCCTCTGCCGC
TTCTACGACCGCCGCGGGCAGGACATCGGCGTGCCGCTGCACGAGCGTGTGGTGGGGGTCGATCTCGACCAGCTCCGCCG
CTCCGAGCGCGTGATCGGCGCCGCGGGCGGGCCGGCCAAGACCGGCCCCATCCTCTCGGCCCTGCGCGGCGAGATCCTCG
ACATTCTCATCACCGACGAGCCCACGGCGCTCGCCCTTCTCGACGCGGCGGAGGCCTGA

Upstream 100 bases:

>100_bases
CATGCTGCACCGCAGATAAACTCGGTGATTGACTTGTTCATATGTTTATTTGACAACTAATATGATCGTAGCCCAAGCGC
GGCGGAAAGGGACGGCATCC

Downstream 100 bases:

>100_bases
CCCATGCCCTATTTCCTCGCCATCGACGCCGGAACCGGCAGCGGCCGCGCCGTCCTCTTCGACGAGACCGGCGCCGAGAT
CGCGGCCTCGGGTCAGGAAT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MAEQTRSDFDEALMARVAWLYYNDGLTQNEVGEILNISRIKVSRLLDQGRSSGLIQVRINSRQQGCLELETRMKREFGLT
DCRVIPESPVEDVNLRVGQAAAQYLMQKLAFGETISVGWGETVTHSIRMLGHTAQERSIGLYSLTGGVQTYVEGMREANW
HRNVNIIPAPLVVSTPELARALMQEPAIAALMARALEADYKLVGIGGLGESATVVTQGYISAGEIDPLRRGGARGDILCR
FYDRRGQDIGVPLHERVVGVDLDQLRRSERVIGAAGGPAKTGPILSALRGEILDILITDEPTALALLDAAEA

Sequences:

>Translated_312_residues
MAEQTRSDFDEALMARVAWLYYNDGLTQNEVGEILNISRIKVSRLLDQGRSSGLIQVRINSRQQGCLELETRMKREFGLT
DCRVIPESPVEDVNLRVGQAAAQYLMQKLAFGETISVGWGETVTHSIRMLGHTAQERSIGLYSLTGGVQTYVEGMREANW
HRNVNIIPAPLVVSTPELARALMQEPAIAALMARALEADYKLVGIGGLGESATVVTQGYISAGEIDPLRRGGARGDILCR
FYDRRGQDIGVPLHERVVGVDLDQLRRSERVIGAAGGPAKTGPILSALRGEILDILITDEPTALALLDAAEA
>Mature_311_residues
AEQTRSDFDEALMARVAWLYYNDGLTQNEVGEILNISRIKVSRLLDQGRSSGLIQVRINSRQQGCLELETRMKREFGLTD
CRVIPESPVEDVNLRVGQAAAQYLMQKLAFGETISVGWGETVTHSIRMLGHTAQERSIGLYSLTGGVQTYVEGMREANWH
RNVNIIPAPLVVSTPELARALMQEPAIAALMARALEADYKLVGIGGLGESATVVTQGYISAGEIDPLRRGGARGDILCRF
YDRRGQDIGVPLHERVVGVDLDQLRRSERVIGAAGGPAKTGPILSALRGEILDILITDEPTALALLDAAEA

Specific function: In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFGE operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho- AI-2, leading to the transcription of the lsr genes [H]

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=301, Percent_Identity=40.531561461794, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI87082414, Length=327, Percent_Identity=27.82874617737, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 34006; Mature: 33875

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQTRSDFDEALMARVAWLYYNDGLTQNEVGEILNISRIKVSRLLDQGRSSGLIQVRIN
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
SRQQGCLELETRMKREFGLTDCRVIPESPVEDVNLRVGQAAAQYLMQKLAFGETISVGWG
CCCCCHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCC
ETVTHSIRMLGHTAQERSIGLYSLTGGVQTYVEGMREANWHRNVNIIPAPLVVSTPELAR
HHHHHHHHHHHCHHHHHCCCEEEECCHHHHHHHHHHHCCCCCCCEEECCCCEECCHHHHH
ALMQEPAIAALMARALEADYKLVGIGGLGESATVVTQGYISAGEIDPLRRGGARGDILCR
HHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCHHHCCCCCCCEEEE
FYDRRGQDIGVPLHERVVGVDLDQLRRSERVIGAAGGPAKTGPILSALRGEILDILITDE
EECCCCCCCCCCHHHHEECCCHHHHHHHHHEEECCCCCCCCCHHHHHHHHHEEEEEECCC
PTALALLDAAEA
CCEEEEEECCCC
>Mature Secondary Structure 
AEQTRSDFDEALMARVAWLYYNDGLTQNEVGEILNISRIKVSRLLDQGRSSGLIQVRIN
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
SRQQGCLELETRMKREFGLTDCRVIPESPVEDVNLRVGQAAAQYLMQKLAFGETISVGWG
CCCCCHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCC
ETVTHSIRMLGHTAQERSIGLYSLTGGVQTYVEGMREANWHRNVNIIPAPLVVSTPELAR
HHHHHHHHHHHCHHHHHCCCEEEECCHHHHHHHHHHHCCCCCCCEEECCCCEECCHHHHH
ALMQEPAIAALMARALEADYKLVGIGGLGESATVVTQGYISAGEIDPLRRGGARGDILCR
HHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCHHHCCCCCCCEEEE
FYDRRGQDIGVPLHERVVGVDLDQLRRSERVIGAAGGPAKTGPILSALRGEILDILITDE
EECCCCCCCCCCHHHHEECCCHHHHHHHHHEEECCCCCCCCCHHHHHHHHHEEEEEECCC
PTALALLDAAEA
CCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA