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The map label for this gene is yckA [H]

Identifier: 77465462

GI number: 77465462

Start: 529593

End: 530258

Strand: Direct

Name: yckA [H]

Synonym: RSP_3460

Alternate gene names: 77465462

Gene position: 529593-530258 (Clockwise)

Preceding gene: 77465461

Following gene: 77465463

Centisome position: 56.16

GC content: 68.62

Gene sequence:

>666_bases
ATGCAGGACTTCATCCGCCTGTTCTTCAATCTCGAGGTCATGGCCCAGACGCTGCCGCTGCTGATGCAGGGGCTCTGGAT
GACGGTCAGGCTCTGTGCCGCCGTCATCGCCCTCGGCCTTGTGGGCGGGCTCTTCCTCGCGCTCGGCGCCCTCTCGCACC
GGCGCTGGCTGCGCTGGCCCGCCTTCGCGGTGATCGATTTCCTGCGCGCGCTGCCGCCCTTGGTGCTCCTGATCTTCATC
TATTCGGGCCTGCCCTTCGCGGGGCTCGCCATCTCGCCCTTCGCGGCGGTGGCGGTGGCCTTCTTCCTCAACAACTCGGC
CTATTACGCCGAGATCTACCGCGCCGGCATCCAGTCGGTGCCCGCAGGCCAGACCGAGGCCGCGCGCGCCTGCGGGCTGA
CCACCGGCCAGACGCTCGCCCATGTGGTGCTGCCGCAGGCGGTGCGCAACGTGCTGCCGGATCTGCTGTCGAACACGGTC
GAGGTGGTCAAGCTCACCTCGCTCGCCTCGGTCGTGTCGCTGGCCGAACTTCTCTACTCGGCCAACATGGCCCGGTCGCT
CACCTACAATGCCTCGCCGCTCGTGCTCGCGGCGCTGGTCTATCTCGTGCTGCTCTGGCCGCTGGTGCGGCTCGTCAGCC
GCTACCAGCGCCGCCTCGCGGCCTGA

Upstream 100 bases:

>100_bases
GCCGCTGACCATGGGCGCCATCGCCTATGTGATCGTGTTCCTCCCGCTCGTGGTGCTGACGCGCCTCCTCGAGCGGCGCT
TCGCCTGGAAGGTCTGAGCC

Downstream 100 bases:

>100_bases
GCACCCCTTTCACCACTTACCTTCAGGGAAGAGACAGATGCGCAAGATGATCGTTGGCGGGGCCCAGATGGGGCCGATCC
AGCAGGCCGACAGCCGCGAG

Product: ABC polar amino acid transporter, inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MQDFIRLFFNLEVMAQTLPLLMQGLWMTVRLCAAVIALGLVGGLFLALGALSHRRWLRWPAFAVIDFLRALPPLVLLIFI
YSGLPFAGLAISPFAAVAVAFFLNNSAYYAEIYRAGIQSVPAGQTEAARACGLTTGQTLAHVVLPQAVRNVLPDLLSNTV
EVVKLTSLASVVSLAELLYSANMARSLTYNASPLVLAALVYLVLLWPLVRLVSRYQRRLAA

Sequences:

>Translated_221_residues
MQDFIRLFFNLEVMAQTLPLLMQGLWMTVRLCAAVIALGLVGGLFLALGALSHRRWLRWPAFAVIDFLRALPPLVLLIFI
YSGLPFAGLAISPFAAVAVAFFLNNSAYYAEIYRAGIQSVPAGQTEAARACGLTTGQTLAHVVLPQAVRNVLPDLLSNTV
EVVKLTSLASVVSLAELLYSANMARSLTYNASPLVLAALVYLVLLWPLVRLVSRYQRRLAA
>Mature_221_residues
MQDFIRLFFNLEVMAQTLPLLMQGLWMTVRLCAAVIALGLVGGLFLALGALSHRRWLRWPAFAVIDFLRALPPLVLLIFI
YSGLPFAGLAISPFAAVAVAFFLNNSAYYAEIYRAGIQSVPAGQTEAARACGLTTGQTLAHVVLPQAVRNVLPDLLSNTV
EVVKLTSLASVVSLAELLYSANMARSLTYNASPLVLAALVYLVLLWPLVRLVSRYQRRLAA

Specific function: Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=220, Percent_Identity=35.4545454545455, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786873, Length=221, Percent_Identity=33.0316742081448, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787030, Length=218, Percent_Identity=34.4036697247706, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082239, Length=203, Percent_Identity=32.0197044334975, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788645, Length=208, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI48994930, Length=142, Percent_Identity=35.9154929577465, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1788646, Length=199, Percent_Identity=27.6381909547739, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1787087, Length=224, Percent_Identity=26.7857142857143, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787086, Length=222, Percent_Identity=28.3783783783784, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24088; Mature: 24088

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDFIRLFFNLEVMAQTLPLLMQGLWMTVRLCAAVIALGLVGGLFLALGALSHRRWLRWP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFAVIDFLRALPPLVLLIFIYSGLPFAGLAISPFAAVAVAFFLNNSAYYAEIYRAGIQSV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
PAGQTEAARACGLTTGQTLAHVVLPQAVRNVLPDLLSNTVEVVKLTSLASVVSLAELLYS
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANMARSLTYNASPLVLAALVYLVLLWPLVRLVSRYQRRLAA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDFIRLFFNLEVMAQTLPLLMQGLWMTVRLCAAVIALGLVGGLFLALGALSHRRWLRWP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFAVIDFLRALPPLVLLIFIYSGLPFAGLAISPFAAVAVAFFLNNSAYYAEIYRAGIQSV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
PAGQTEAARACGLTTGQTLAHVVLPQAVRNVLPDLLSNTVEVVKLTSLASVVSLAELLYS
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANMARSLTYNASPLVLAALVYLVLLWPLVRLVSRYQRRLAA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377 [H]