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The map label for this gene is dam [C]

Identifier: 77465361

GI number: 77465361

Start: 423689

End: 424477

Strand: Direct

Name: dam [C]

Synonym: RSP_3360

Alternate gene names: 77465361

Gene position: 423689-424477 (Clockwise)

Preceding gene: 77465360

Following gene: 77465362

Centisome position: 44.93

GC content: 68.19

Gene sequence:

>789_bases
GTGGCGCCCTGGATCGGCGGCAAGCGCAACCTCGCCCGCCGGATCTGCGCCATCCTCGACCGCAGCCCCTGCCTCACCTA
TGCCGAGCCCTTCGTCGGCATGGCCGGGATCTTCCTGCGCCGCAGCTCGCGCCCCCGGGCCGAGGTCATCAACGACCGCG
GCCGCGACGTGGCGAACCTGTTCCGCATTCTGCAACGGCATTATCCGCAGTTCCTCGACACGCTGCGTTTCCAGCTGACC
ACGCGGGCCGAATTCGAGCGTCTGGGCGCCACCGATCCCGACACGCTGACCGACCTCGAACGGGCGGCGCGGTTCCTCTA
CCTCCAGCGCACCGCCTTCGGCGGCAAGGTGAGCGGGCGGAACTTCGGCGTCTCCTCGCATCGGCCTGGGCGGTTCAACC
TCACCACGCTGGAGCCCATGCTCGAGGACCTGCACAGCCGCCTCGCCGGCGTGATCGTCGAATGCCTGGACTGGGCCGAC
TTCCTCGCCCGCTACGACCGGCCCGAGACGCTCTTCTATCTCGACCCGCCGTACTGGGGATCCGAGACCGACTACGGCCG
CGGCCTGTTCCAGCGCGAGGACTTCGGGCTGATGGCCGAGCGGCTGGCCAAGTTGCAGGGCCGCTTCCTCCTCTCGATCA
ACGATGTGCCCCAGATCCGCGCGATCTTCGGCAGGTTCCGGATCACTGAGGTGACGACCACCTATTCGATCAGCGGCAGC
GCGAAGGGCAATGGCACGGCGCGGCCGGAGCTGCTGGTCTCGAACTGGGACATCGGCGAAGAGGGCTGA

Upstream 100 bases:

>100_bases
CCAGACAAGAATCATGGCCGCTCCCGCACCCTTGCGGGCACGCCGAAGAGACACGAACCAGATGAAGAGTCCACTCTCGC
CCGTCACCCCGCTGCAGCCT

Downstream 100 bases:

>100_bases
GGAAGGTGCCGTGGGCGGAGCGATCCGCCCGCGGCGACCTTGGCAGGGTATGAGGCCCCGCGTCCGACGCCGCGACCCAA
ACCAGATCTCGTGCTCTTGG

Product: adenine specific DNA methyltransferase, D12 class

Products: S-adenosyl-L-homocysteine; DNA methylaminopurine [C]

Alternate protein names: DNA Adenine Methylase; Methyltransferase; Adenine-Specific DNA Methyltransferase; Site-Specific DNA Methylase; N6 Adenine-Specific DNA Methyltransferase; Site-Specific DNA-Methyltransferase; Methylase; Adenine-Specific DNA-Methyltransferase; N6 Adenine-Specific DNA Methyltransferase Protein; Phage DNA Adenine Methylase; Type II DNA Methyltransferase; Prophage; DNA Adenine Methyltransferase; Adenine Specific DNA Methyltransferase; Phage Associated Type II DNA-Methyltransferase; Ype IIs Methyltransferase M.AlwI; Prophage DNA Adenine Methylase; Cytosine-Specific DNA Methyltransferase; DNA Methyltransferase; Phage_related Methylase; DNA Adenine Methylase Subfamily; Prophage DNA Methylase; LOW QUALITY PROTEIN DNA Adenine Methylase; Methylase LlaDCHIA; Dam Methylase; Phage-Related Methylase; Adenine-Specific Methyltransferase; DNA Methylase; Type IIs Methyltransferase; Site-Specific DNA Methylase Protein

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MAPWIGGKRNLARRICAILDRSPCLTYAEPFVGMAGIFLRRSSRPRAEVINDRGRDVANLFRILQRHYPQFLDTLRFQLT
TRAEFERLGATDPDTLTDLERAARFLYLQRTAFGGKVSGRNFGVSSHRPGRFNLTTLEPMLEDLHSRLAGVIVECLDWAD
FLARYDRPETLFYLDPPYWGSETDYGRGLFQREDFGLMAERLAKLQGRFLLSINDVPQIRAIFGRFRITEVTTTYSISGS
AKGNGTARPELLVSNWDIGEEG

Sequences:

>Translated_262_residues
MAPWIGGKRNLARRICAILDRSPCLTYAEPFVGMAGIFLRRSSRPRAEVINDRGRDVANLFRILQRHYPQFLDTLRFQLT
TRAEFERLGATDPDTLTDLERAARFLYLQRTAFGGKVSGRNFGVSSHRPGRFNLTTLEPMLEDLHSRLAGVIVECLDWAD
FLARYDRPETLFYLDPPYWGSETDYGRGLFQREDFGLMAERLAKLQGRFLLSINDVPQIRAIFGRFRITEVTTTYSISGS
AKGNGTARPELLVSNWDIGEEG
>Mature_261_residues
APWIGGKRNLARRICAILDRSPCLTYAEPFVGMAGIFLRRSSRPRAEVINDRGRDVANLFRILQRHYPQFLDTLRFQLTT
RAEFERLGATDPDTLTDLERAARFLYLQRTAFGGKVSGRNFGVSSHRPGRFNLTTLEPMLEDLHSRLAGVIVECLDWADF
LARYDRPETLFYLDPPYWGSETDYGRGLFQREDFGLMAERLAKLQGRFLLSINDVPQIRAIFGRFRITEVTTTYSISGSA
KGNGTARPELLVSNWDIGEEG

Specific function: Methylates DNA Within The Sequence GATC And Protects The DNA From Cleavage By The Restriction Endonuclease Mboi. Although It Shares Sequence Specificity With A Number Of Type II Restriction Endonucleases And Methylases, It Is Thought To Act In Postreplica

COG id: COG0338

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.72 [C]

Molecular weight: Translated: 29861; Mature: 29730

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPWIGGKRNLARRICAILDRSPCLTYAEPFVGMAGIFLRRSSRPRAEVINDRGRDVANL
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHH
FRILQRHYPQFLDTLRFQLTTRAEFERLGATDPDTLTDLERAARFLYLQRTAFGGKVSGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
NFGVSSHRPGRFNLTTLEPMLEDLHSRLAGVIVECLDWADFLARYDRPETLFYLDPPYWG
CCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
SETDYGRGLFQREDFGLMAERLAKLQGRFLLSINDVPQIRAIFGRFRITEVTTTYSISGS
CCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHEEEEEEEEEEECCC
AKGNGTARPELLVSNWDIGEEG
CCCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
APWIGGKRNLARRICAILDRSPCLTYAEPFVGMAGIFLRRSSRPRAEVINDRGRDVANL
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHH
FRILQRHYPQFLDTLRFQLTTRAEFERLGATDPDTLTDLERAARFLYLQRTAFGGKVSGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
NFGVSSHRPGRFNLTTLEPMLEDLHSRLAGVIVECLDWADFLARYDRPETLFYLDPPYWG
CCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
SETDYGRGLFQREDFGLMAERLAKLQGRFLLSINDVPQIRAIFGRFRITEVTTTYSISGS
CCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHEEEEEEEEEEECCC
AKGNGTARPELLVSNWDIGEEG
CCCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; DNA adenine; DNA [C]

Specific reaction: S-Adenosyl-L-methionine + DNA adenine =S-adenosyl-L-homocysteine + DNA methylaminopurine Protein + DNA = Protein-DNA [C]

General reaction: Methyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA