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The map label for this gene is fbpB [H]

Identifier: 77465272

GI number: 77465272

Start: 322534

End: 323529

Strand: Direct

Name: fbpB [H]

Synonym: RSP_3266

Alternate gene names: 77465272

Gene position: 322534-323529 (Clockwise)

Preceding gene: 77465267

Following gene: 77465273

Centisome position: 34.2

GC content: 69.48

Gene sequence:

>996_bases
ATGGCCATCGAGCTGGAGGACCTGGGGCTGAGCCCCGATGTGGCGGACGTGATGCAGCGTCTGGCGCGCGTGGGGGCAGG
CATCGCCCGCATCATCTCGCGCAACGGGCTCGAGCGCGATCTGGGCGCGGGCGTCGGCACCAATGCCGGAGGAGACGGGC
AGAAGGCGCTCGACGTGATCGCGGACGACGCGTTCCGCGCGGCGCTCGAAGGCTCTGCGGTGGCTTATTACGCCTCCGAG
GAGCAGGACGAAGTGGTGACGCTGGGCGAGGGAAGCCTCGCGCTCGCCATCGACCCGCTGGACGGCTCGTCCAACATCGA
TGTGAACGTGTCGATCGGGACGATCTTCTCGATCTTCCCGGCGGCGGCTGGCCCCGAGGCCAGCTTCCTGCGCCCGGGCA
CCGAGCAGATTGCCGGCGGCTACATCATCTACGGGCCGCAATGCGCGCTGGTCTGCAGCTTCGGGCAGGGCGTGCAGCAC
TGGGTGCTCGACCTCGATGCGGGCATCTTCCGGCGGATGCCCGACATCCGCCCGCTGCCGGCCGAGACGTCCGAGTTTGC
GATCAACGCCTCGAACTACCGCCACTGGCCGCAGCCGATCCGCGCCTTCGTCGACGATCTGGTCGCCGGGGCCGAGGGGC
CGCGCGGCAAGAACTTCAACATGCGCTGGATCGCCTCGCTGGTGGCCGAGACGCACCGCATCCTGATGCGGGGCGGGGTG
TTTCTCTATCCCGGCGACGAGCGCAAGGGCTACGAGCGGGGCCGGCTGCGCCATGTCTACGAATGCGCGCCCATCGCCTT
CCTGATCGCGAATGTCGGGGGGGGCGCCACCGACGGCTGCGCCGACATCCTGACCGCGCTGCCCGACCGGCTGCACGCCC
GCACCCCCTTCGTCTTCGGCTGCGCGAGCAAGGTCGCCCGCGTCGCCGCCTATCACGATCTGGCCTGCGAAGAGACGTCC
GCTCTCTTCGGCAGCCGGGGCCTGTTCCGGAGTTAA

Upstream 100 bases:

>100_bases
GCCGAGAGATTAAAATTTTTAGAAGGCATCTTGGCTATTTTCAAATATTCATGAACCGGATCCTGACGCAACGTCCGCCG
CGACAGAGGCAGGAGGAGCC

Downstream 100 bases:

>100_bases
AGAGTGTCGAAGAAATATCCCATCATTTCCGTGGTCGGCTCGTCCGGCGCGGGCACCTCGACGGTCAAGAACACGTTCGA
GCAGATCTTCCGCCGCGAGG

Product: D-fructose 1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2 [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MAIELEDLGLSPDVADVMQRLARVGAGIARIISRNGLERDLGAGVGTNAGGDGQKALDVIADDAFRAALEGSAVAYYASE
EQDEVVTLGEGSLALAIDPLDGSSNIDVNVSIGTIFSIFPAAAGPEASFLRPGTEQIAGGYIIYGPQCALVCSFGQGVQH
WVLDLDAGIFRRMPDIRPLPAETSEFAINASNYRHWPQPIRAFVDDLVAGAEGPRGKNFNMRWIASLVAETHRILMRGGV
FLYPGDERKGYERGRLRHVYECAPIAFLIANVGGGATDGCADILTALPDRLHARTPFVFGCASKVARVAAYHDLACEETS
ALFGSRGLFRS

Sequences:

>Translated_331_residues
MAIELEDLGLSPDVADVMQRLARVGAGIARIISRNGLERDLGAGVGTNAGGDGQKALDVIADDAFRAALEGSAVAYYASE
EQDEVVTLGEGSLALAIDPLDGSSNIDVNVSIGTIFSIFPAAAGPEASFLRPGTEQIAGGYIIYGPQCALVCSFGQGVQH
WVLDLDAGIFRRMPDIRPLPAETSEFAINASNYRHWPQPIRAFVDDLVAGAEGPRGKNFNMRWIASLVAETHRILMRGGV
FLYPGDERKGYERGRLRHVYECAPIAFLIANVGGGATDGCADILTALPDRLHARTPFVFGCASKVARVAAYHDLACEETS
ALFGSRGLFRS
>Mature_330_residues
AIELEDLGLSPDVADVMQRLARVGAGIARIISRNGLERDLGAGVGTNAGGDGQKALDVIADDAFRAALEGSAVAYYASEE
QDEVVTLGEGSLALAIDPLDGSSNIDVNVSIGTIFSIFPAAAGPEASFLRPGTEQIAGGYIIYGPQCALVCSFGQGVQHW
VLDLDAGIFRRMPDIRPLPAETSEFAINASNYRHWPQPIRAFVDDLVAGAEGPRGKNFNMRWIASLVAETHRILMRGGVF
LYPGDERKGYERGRLRHVYECAPIAFLIANVGGGATDGCADILTALPDRLHARTPFVFGCASKVARVAAYHDLACEETSA
LFGSRGLFRS

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=300, Percent_Identity=29.6666666666667, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI189083692, Length=302, Percent_Identity=30.4635761589404, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI16579888, Length=302, Percent_Identity=30.4635761589404, Blast_Score=145, Evalue=6e-35,
Organism=Escherichia coli, GI1790679, Length=293, Percent_Identity=37.542662116041, Blast_Score=191, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17508131, Length=291, Percent_Identity=34.020618556701, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6323409, Length=303, Percent_Identity=33.6633663366337, Blast_Score=171, Evalue=2e-43,
Organism=Drosophila melanogaster, GI45550998, Length=307, Percent_Identity=31.2703583061889, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI19921562, Length=307, Percent_Identity=31.2703583061889, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR020548 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35256; Mature: 35125

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00124 FBPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIELEDLGLSPDVADVMQRLARVGAGIARIISRNGLERDLGAGVGTNAGGDGQKALDVI
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHH
ADDAFRAALEGSAVAYYASEEQDEVVTLGEGSLALAIDPLDGSSNIDVNVSIGTIFSIFP
HHHHHHHHHCCCEEEEEECCCCCCEEEECCCCEEEEEECCCCCCCEEEEEEHHHHHHHHC
AAAGPEASFLRPGTEQIAGGYIIYGPQCALVCSFGQGVQHWVLDLDAGIFRRMPDIRPLP
CCCCCCCHHCCCCHHHHCCCEEEECCCEEEEEECCCCHHHHHHHHCCHHHHCCCCCCCCC
AETSEFAINASNYRHWPQPIRAFVDDLVAGAEGPRGKNFNMRWIASLVAETHRILMRGGV
CCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCE
FLYPGDERKGYERGRLRHVYECAPIAFLIANVGGGATDGCADILTALPDRLHARTPFVFG
EEEECCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHCHHHHHCCCCEEEH
CASKVARVAAYHDLACEETSALFGSRGLFRS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AIELEDLGLSPDVADVMQRLARVGAGIARIISRNGLERDLGAGVGTNAGGDGQKALDVI
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHH
ADDAFRAALEGSAVAYYASEEQDEVVTLGEGSLALAIDPLDGSSNIDVNVSIGTIFSIFP
HHHHHHHHHCCCEEEEEECCCCCCEEEECCCCEEEEEECCCCCCCEEEEEEHHHHHHHHC
AAAGPEASFLRPGTEQIAGGYIIYGPQCALVCSFGQGVQHWVLDLDAGIFRRMPDIRPLP
CCCCCCCHHCCCCHHHHCCCEEEECCCEEEEEECCCCHHHHHHHHCCHHHHCCCCCCCCC
AETSEFAINASNYRHWPQPIRAFVDDLVAGAEGPRGKNFNMRWIASLVAETHRILMRGGV
CCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCE
FLYPGDERKGYERGRLRHVYECAPIAFLIANVGGGATDGCADILTALPDRLHARTPFVFG
EEEECCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHCHHHHHCCCCEEEH
CASKVARVAAYHDLACEETSALFGSRGLFRS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA