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The map label for this gene is mprF [H]

Identifier: 77465175

GI number: 77465175

Start: 212647

End: 215262

Strand: Reverse

Name: mprF [H]

Synonym: RSP_3161

Alternate gene names: 77465175

Gene position: 215262-212647 (Counterclockwise)

Preceding gene: 77465176

Following gene: 77465174

Centisome position: 22.83

GC content: 69.38

Gene sequence:

>2616_bases
ATGTCCTGGCGCAGCGAGACGCCCGAAGACGCGACGCCTCCGGACGAGGCCCTCCCGCCCCGGTCGCGCCCCGTGCGCGA
CTGGCTCAGCCGCAACCGCACCGTGCTGCTCGCGCTGGTGACATGGGTCGTGTTCGCGGCAGTCGCCTACACGACCTACC
GGATCACGGGCGACATCCGCTACAAGGACATCCTGCACGCGCTCGAGGCGACGACCTGGACCGACATCCTGATCGCGGGC
TTCTTCACCGTGGTGAGCTTCGTCCTGCTCGCGGGCTACGATGTCAACGCGCTGCGCCATCTGGGCAAGCAGGCCAATCT
GGTGCAGGTGGGCATGATCGCCTTCAGCGCCTATGCGATCGGCAACACCGTGGGGTTCGGCCCGCTGTCGGCCGGGGCGG
TGCGCTACCGCGGTTACAGCCGGCTCGGCCTCTCTGGCGAGCAGATCGCCGGCGTGATCGCCTTCGTGACCCTCTCCTTC
GGCCTCGGTCTGACGGTCACCACCGCGCTCGCGGCGCTGGTGGCGGCCGATCAGGTGGCGGGCTTTGCCGGTCTCACGCC
GCAGATGCTACGGCTTCTGTCGGCGGCCCTCCTGCTCGCGCTGACGGTGGCGGCCGTGATCCTCTGGCGCAGCGACGGGT
GGCTGCGGCCGCACATGCCGCGCCCGGGCATCGCACTGGGCCAGCTGGCCATCACCGCGGCCGATCTCATGGTCTGCGCC
ACTGTCCTCTGGGTGCTCCTGCCGCAGGATCTGGAGGTCAGCTGGATCTCCTTCGTCATCATCTATGCCATCGCCATCGG
CCTCGGCGTGCTGAGCCACGTCCCGGCGGGACTGGGCGTCCTCGAGGCGGTGATCCTGACCACGCTCGGCGGCTCGACGG
GGACGGACGCTCTGCTGGGGTCGCTCGTCCTCTACCGGGTTATCTACCATGTCGTGCCCCTCCTGATCGCGGTGGTGGTG
GTGGCCTGGACCGAGGCGCTCGAGGCGTTCCATTCGCCGCGCCTCGAATGGGCGGAGCGGATGGGCACGCTGCTCGCGCC
CTCGCTCCTCGGCTCGCTCGCGGTGATCTGCGGCGTCATGCTGATCTTCTCGAGCGTGATCCCCGCGCGCGAGGCGAACC
TCGTCTGGCTCGCGGGCTACGTCCCCGCCCTGCTCATCGAAGGGGCGCATTTCCTGTCGAGCCTGATCGGCCTCGTGCTG
TTCGTCGCGGCCCGGGGCCTCACGCAACGGCTGGACGGCGCCTACTGGCTGACGCTGGGTGCGGCGAGCGCGGCCTTCCT
CTTCACCTTCGTCAAGGCGCTGGCCCCCTACGAGGCGGTGATGCTGGCCGCCCTGATCGGCTTTCTCCTCCTGAGCCGGC
CGCTCTTCGACCGGCCCGCCTTGCTCTTCTCGCAGACGCTGACGCCGCCCTGGATCGCGGGGATCGCCACCGTGGCCATT
TCGGCCATCACGATCCTGCTCTTCGTTCAGAAGGACGTGGCATACAGCCACGACCTCTGGTGGCAGTTCGAGATCTCGGC
CGAGGCGCCGCGCGGGCTGCGCGCCCTTCTGGGCGTAGTGGTGCTGTCGGCGCTGATTGCGATCCGCAGCCTGCTGCAGC
CCTCCCGCCCCGAGCCCGGGATGCCCGACGAGGCCGAGCTGCAGAAGGCGCTCGCCATCGTCGAGGGGCAGGACATGGGC
GAGGCCAATCTCGTGCGGATGCGCGACAAGAGCCTGATCTTCTCGGACGCGGGCGACGCCTTCCTCATGTATGCGGTGCA
GGGCCAGTCCTGGATCTCGCTCTTCGGGCCCATCGGCGCCCCGCGCGCGCAGGCCGAACTGATCTGGCGCTTCATCGAGA
CCGCGCGCGCCAAGGGCGGCCGGCCGGTCTTCTATCAGGTGCCGCCCTCGCTTCTGCCGCTCTGCGCCGACGCGGGCCTG
CGCGGGCTGAAGCTGGGCGAGCGGGCGGTGGTCGATCTCGAGGCGATGGACCTGCAATCGAGCCAGTGGGCCGAGCAGCG
GCAGGCCCTGCGCAAGGGCGAGCGGATGGGGCTGGCCTTCGAGCTGCTGGAGCCCGCCGACCTCGGCCCGATCCTCGACG
AGCTCCAGCAGGTTTCGGACGCATGGCTCGCGCATCACGACACCCGCGAGAAAGGCTTCGCCCTCGGCCGGTTCGAGCGC
GACTATGTGGCCGAGCAGCCGGTGGCGGTGCTGCGCGCCGAGGGACGCATCGTGGCCTTCGCCACGGTCATGCAGACGGG
AACGAAGGCCGAGGCCACGCTCGATCTGATGCGCTTTGCCCGCAGCGCGCCGCCGGGCTCGATGGATGTGCTGCTGTGCA
ACCTGCTGGTCGAGATGAAGCGGCAGGGCTTCCGCAGCTTCAACCTCGGGATGGCGCCGCTGTCGGGCATCACCGCACAT
CAGGCCGCGCCGTTCTGGAACCATCTCGGCCAGTCCGTCTTCGAACATGGCGAGCGGTTCTACAATTTCCGCGGCCTGCG
GTCCTTCAAGGCCAAATACCGTCCCGACTGGCAGTCGCGCTACCTCGTGACGCCGGGCGGGGTCTCGCCTCTGGCGGCAC
TGGTCGATGTCACGCTGCTGATCGGCGGCGGCCTCCGGGGCGTGATGCGGAAGTGA

Upstream 100 bases:

>100_bases
AGGAGGCTGTGCGCCGCGCCCCGGGCTTTCTTGCCGGGCCGGGCGCAGCATGAGGAGCAACGCCGGAGCCGTCAGGCGGG
CGATCCAGAAGGGGCACTGC

Downstream 100 bases:

>100_bases
GCCGCGCGGCTGCGGCCGGAGCCGCGCCCTCCGCAGCACCCGAGGCCCGCGGCGGAATGCCGCAGCGCCGGTGCCCGAAG
CCCTTGCTGCAGGGCGGCAG

Product: hypothetical protein

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase; Multiple peptide resistance factor [H]

Number of amino acids: Translated: 871; Mature: 870

Protein sequence:

>871_residues
MSWRSETPEDATPPDEALPPRSRPVRDWLSRNRTVLLALVTWVVFAAVAYTTYRITGDIRYKDILHALEATTWTDILIAG
FFTVVSFVLLAGYDVNALRHLGKQANLVQVGMIAFSAYAIGNTVGFGPLSAGAVRYRGYSRLGLSGEQIAGVIAFVTLSF
GLGLTVTTALAALVAADQVAGFAGLTPQMLRLLSAALLLALTVAAVILWRSDGWLRPHMPRPGIALGQLAITAADLMVCA
TVLWVLLPQDLEVSWISFVIIYAIAIGLGVLSHVPAGLGVLEAVILTTLGGSTGTDALLGSLVLYRVIYHVVPLLIAVVV
VAWTEALEAFHSPRLEWAERMGTLLAPSLLGSLAVICGVMLIFSSVIPAREANLVWLAGYVPALLIEGAHFLSSLIGLVL
FVAARGLTQRLDGAYWLTLGAASAAFLFTFVKALAPYEAVMLAALIGFLLLSRPLFDRPALLFSQTLTPPWIAGIATVAI
SAITILLFVQKDVAYSHDLWWQFEISAEAPRGLRALLGVVVLSALIAIRSLLQPSRPEPGMPDEAELQKALAIVEGQDMG
EANLVRMRDKSLIFSDAGDAFLMYAVQGQSWISLFGPIGAPRAQAELIWRFIETARAKGGRPVFYQVPPSLLPLCADAGL
RGLKLGERAVVDLEAMDLQSSQWAEQRQALRKGERMGLAFELLEPADLGPILDELQQVSDAWLAHHDTREKGFALGRFER
DYVAEQPVAVLRAEGRIVAFATVMQTGTKAEATLDLMRFARSAPPGSMDVLLCNLLVEMKRQGFRSFNLGMAPLSGITAH
QAAPFWNHLGQSVFEHGERFYNFRGLRSFKAKYRPDWQSRYLVTPGGVSPLAALVDVTLLIGGGLRGVMRK

Sequences:

>Translated_871_residues
MSWRSETPEDATPPDEALPPRSRPVRDWLSRNRTVLLALVTWVVFAAVAYTTYRITGDIRYKDILHALEATTWTDILIAG
FFTVVSFVLLAGYDVNALRHLGKQANLVQVGMIAFSAYAIGNTVGFGPLSAGAVRYRGYSRLGLSGEQIAGVIAFVTLSF
GLGLTVTTALAALVAADQVAGFAGLTPQMLRLLSAALLLALTVAAVILWRSDGWLRPHMPRPGIALGQLAITAADLMVCA
TVLWVLLPQDLEVSWISFVIIYAIAIGLGVLSHVPAGLGVLEAVILTTLGGSTGTDALLGSLVLYRVIYHVVPLLIAVVV
VAWTEALEAFHSPRLEWAERMGTLLAPSLLGSLAVICGVMLIFSSVIPAREANLVWLAGYVPALLIEGAHFLSSLIGLVL
FVAARGLTQRLDGAYWLTLGAASAAFLFTFVKALAPYEAVMLAALIGFLLLSRPLFDRPALLFSQTLTPPWIAGIATVAI
SAITILLFVQKDVAYSHDLWWQFEISAEAPRGLRALLGVVVLSALIAIRSLLQPSRPEPGMPDEAELQKALAIVEGQDMG
EANLVRMRDKSLIFSDAGDAFLMYAVQGQSWISLFGPIGAPRAQAELIWRFIETARAKGGRPVFYQVPPSLLPLCADAGL
RGLKLGERAVVDLEAMDLQSSQWAEQRQALRKGERMGLAFELLEPADLGPILDELQQVSDAWLAHHDTREKGFALGRFER
DYVAEQPVAVLRAEGRIVAFATVMQTGTKAEATLDLMRFARSAPPGSMDVLLCNLLVEMKRQGFRSFNLGMAPLSGITAH
QAAPFWNHLGQSVFEHGERFYNFRGLRSFKAKYRPDWQSRYLVTPGGVSPLAALVDVTLLIGGGLRGVMRK
>Mature_870_residues
SWRSETPEDATPPDEALPPRSRPVRDWLSRNRTVLLALVTWVVFAAVAYTTYRITGDIRYKDILHALEATTWTDILIAGF
FTVVSFVLLAGYDVNALRHLGKQANLVQVGMIAFSAYAIGNTVGFGPLSAGAVRYRGYSRLGLSGEQIAGVIAFVTLSFG
LGLTVTTALAALVAADQVAGFAGLTPQMLRLLSAALLLALTVAAVILWRSDGWLRPHMPRPGIALGQLAITAADLMVCAT
VLWVLLPQDLEVSWISFVIIYAIAIGLGVLSHVPAGLGVLEAVILTTLGGSTGTDALLGSLVLYRVIYHVVPLLIAVVVV
AWTEALEAFHSPRLEWAERMGTLLAPSLLGSLAVICGVMLIFSSVIPAREANLVWLAGYVPALLIEGAHFLSSLIGLVLF
VAARGLTQRLDGAYWLTLGAASAAFLFTFVKALAPYEAVMLAALIGFLLLSRPLFDRPALLFSQTLTPPWIAGIATVAIS
AITILLFVQKDVAYSHDLWWQFEISAEAPRGLRALLGVVVLSALIAIRSLLQPSRPEPGMPDEAELQKALAIVEGQDMGE
ANLVRMRDKSLIFSDAGDAFLMYAVQGQSWISLFGPIGAPRAQAELIWRFIETARAKGGRPVFYQVPPSLLPLCADAGLR
GLKLGERAVVDLEAMDLQSSQWAEQRQALRKGERMGLAFELLEPADLGPILDELQQVSDAWLAHHDTREKGFALGRFERD
YVAEQPVAVLRAEGRIVAFATVMQTGTKAEATLDLMRFARSAPPGSMDVLLCNLLVEMKRQGFRSFNLGMAPLSGITAHQ
AAPFWNHLGQSVFEHGERFYNFRGLRSFKAKYRPDWQSRYLVTPGGVSPLAALVDVTLLIGGGLRGVMRK

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787006, Length=286, Percent_Identity=27.6223776223776, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 94332; Mature: 94200

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWRSETPEDATPPDEALPPRSRPVRDWLSRNRTVLLALVTWVVFAAVAYTTYRITGDIR
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCCH
YKDILHALEATTWTDILIAGFFTVVSFVLLAGYDVNALRHLGKQANLVQVGMIAFSAYAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHH
GNTVGFGPLSAGAVRYRGYSRLGLSGEQIAGVIAFVTLSFGLGLTVTTALAALVAADQVA
CCCCCCCCCCCCHHEECCCHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GFAGLTPQMLRLLSAALLLALTVAAVILWRSDGWLRPHMPRPGIALGQLAITAADLMVCA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TVLWVLLPQDLEVSWISFVIIYAIAIGLGVLSHVPAGLGVLEAVILTTLGGSTGTDALLG
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHH
SLVLYRVIYHVVPLLIAVVVVAWTEALEAFHSPRLEWAERMGTLLAPSLLGSLAVICGVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIFSSVIPAREANLVWLAGYVPALLIEGAHFLSSLIGLVLFVAARGLTQRLDGAYWLTLG
HHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEH
AASAAFLFTFVKALAPYEAVMLAALIGFLLLSRPLFDRPALLFSQTLTPPWIAGIATVAI
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHH
SAITILLFVQKDVAYSHDLWWQFEISAEAPRGLRALLGVVVLSALIAIRSLLQPSRPEPG
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MPDEAELQKALAIVEGQDMGEANLVRMRDKSLIFSDAGDAFLMYAVQGQSWISLFGPIGA
CCCHHHHHHHHHHHCCCCCCCCHHEEECCCCEEEECCCCEEEEEEECCCHHHHHHCCCCC
PRAQAELIWRFIETARAKGGRPVFYQVPPSLLPLCADAGLRGLKLGERAVVDLEAMDLQS
CHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCHHEEEHHHHCCCH
SQWAEQRQALRKGERMGLAFELLEPADLGPILDELQQVSDAWLAHHDTREKGFALGRFER
HHHHHHHHHHHCCHHCCCHHEECCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCH
DYVAEQPVAVLRAEGRIVAFATVMQTGTKAEATLDLMRFARSAPPGSMDVLLCNLLVEMK
HHHHCCCHHHHCCCCCEEEEHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RQGFRSFNLGMAPLSGITAHQAAPFWNHLGQSVFEHGERFYNFRGLRSFKAKYRPDWQSR
HCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
YLVTPGGVSPLAALVDVTLLIGGGLRGVMRK
EEECCCCCHHHHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure 
SWRSETPEDATPPDEALPPRSRPVRDWLSRNRTVLLALVTWVVFAAVAYTTYRITGDIR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCCH
YKDILHALEATTWTDILIAGFFTVVSFVLLAGYDVNALRHLGKQANLVQVGMIAFSAYAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHH
GNTVGFGPLSAGAVRYRGYSRLGLSGEQIAGVIAFVTLSFGLGLTVTTALAALVAADQVA
CCCCCCCCCCCCHHEECCCHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GFAGLTPQMLRLLSAALLLALTVAAVILWRSDGWLRPHMPRPGIALGQLAITAADLMVCA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TVLWVLLPQDLEVSWISFVIIYAIAIGLGVLSHVPAGLGVLEAVILTTLGGSTGTDALLG
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHH
SLVLYRVIYHVVPLLIAVVVVAWTEALEAFHSPRLEWAERMGTLLAPSLLGSLAVICGVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIFSSVIPAREANLVWLAGYVPALLIEGAHFLSSLIGLVLFVAARGLTQRLDGAYWLTLG
HHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEH
AASAAFLFTFVKALAPYEAVMLAALIGFLLLSRPLFDRPALLFSQTLTPPWIAGIATVAI
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHH
SAITILLFVQKDVAYSHDLWWQFEISAEAPRGLRALLGVVVLSALIAIRSLLQPSRPEPG
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MPDEAELQKALAIVEGQDMGEANLVRMRDKSLIFSDAGDAFLMYAVQGQSWISLFGPIGA
CCCHHHHHHHHHHHCCCCCCCCHHEEECCCCEEEECCCCEEEEEEECCCHHHHHHCCCCC
PRAQAELIWRFIETARAKGGRPVFYQVPPSLLPLCADAGLRGLKLGERAVVDLEAMDLQS
CHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCHHEEEHHHHCCCH
SQWAEQRQALRKGERMGLAFELLEPADLGPILDELQQVSDAWLAHHDTREKGFALGRFER
HHHHHHHHHHHCCHHCCCHHEECCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCH
DYVAEQPVAVLRAEGRIVAFATVMQTGTKAEATLDLMRFARSAPPGSMDVLLCNLLVEMK
HHHHCCCHHHHCCCCCEEEEHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RQGFRSFNLGMAPLSGITAHQAAPFWNHLGQSVFEHGERFYNFRGLRSFKAKYRPDWQSR
HCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
YLVTPGGVSPLAALVDVTLLIGGGLRGVMRK
EEECCCCCHHHHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11342591; 12496209 [H]