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The map label for this gene is 77465152

Identifier: 77465152

GI number: 77465152

Start: 188634

End: 189473

Strand: Direct

Name: 77465152

Synonym: RSP_3138

Alternate gene names: NA

Gene position: 188634-189473 (Clockwise)

Preceding gene: 77465149

Following gene: 77465154

Centisome position: 20.0

GC content: 73.21

Gene sequence:

>840_bases
ATGAGCTGGGAAGTGTTCGATCCCCGCGTCTGCGGCCTGGGCGAGGGGCCGCTCTGGCATCCCGAGCGGCAGCAGTTCCT
CTGGTTCGACATCCTCGGACGGCGCCTGCTGGGTGAGGGAGGTGCGGCCTGGACCTTCGACCGGGCGGTCACGGCGGCGG
GCTGGATCGACCGCGACCGGCTGCTCGTCGCCACGGAGACGGGGCTCGCGGTCCTCGATCTGCAGAGGCGCACGCTCGAC
CCGCTGCTGGCGGTCGAGGCGGATCGGCCCGAGACGCGCTCGAACGACGGGCGCGCCGACCGGCAGGGCGGGTTCTGGTT
CGGCACGATGGGCAAGGAAGCCCAGTCCGGGGCGGGCAGCCTCTACCGCTACCACCGTGGACGCATTGAGCGGCTGGTGG
AGGGCCTCACCATCCCCAACGCGATCTGCTTCTCGCCCGACGGCCGGACGGCCTATTACTCCGACACGGACCGGCAGCTG
GTCTGGACCCAGCGGCTCGATGCCGAGGGCTGGCCCGTGGGCGAGCGGGAGCTCTTCCTCGATCTCGCGGACGAGGGGCT
CAATCCCGATGGGGCGGTGATCGACGCCGAAGGCGGCTTCTGCTGCGCCGCCTGGGGGGCGGGGGCGGTGCTGCGGTTCG
ATGCGCGGGGGCGGCAGACGCACCGGCTTGCCGTCGGCGGGCGGCAACCCTCCTGCCCGGCCTTCGGCGGGCCGGAGTTC
GACCGGCTCCTCGTGACGACGGCGACGGAAGGGATGGAGGATCCGGGCCCGGGCGAGGGCCTGCCCTACCTCCTGCGGCC
GGGTCTCCGCGGGCTGGCCGAGCCGCGGGTGACGCTCTGA

Upstream 100 bases:

>100_bases
CGGAGGACCACATGCCGACCGACATGCCGCTTTATCCAGCCATCGCGATGAGAGGGACGTGCGAGGTCCCGTCCCGGGTG
CTGCCTGCCACAGGTGCGGC

Downstream 100 bases:

>100_bases
CGCGGCCGGGGTCACTCTGATGCCGGGAGCGCCTCCTGTCGATGTGAGTTCCTGTCGGACGCGGAGAAAGGGAGAGGTTC
CGCGGCTATCGCGCCGTGCT

Product: gluconolactonase

Products: D-gluconate

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MSWEVFDPRVCGLGEGPLWHPERQQFLWFDILGRRLLGEGGAAWTFDRAVTAAGWIDRDRLLVATETGLAVLDLQRRTLD
PLLAVEADRPETRSNDGRADRQGGFWFGTMGKEAQSGAGSLYRYHRGRIERLVEGLTIPNAICFSPDGRTAYYSDTDRQL
VWTQRLDAEGWPVGERELFLDLADEGLNPDGAVIDAEGGFCCAAWGAGAVLRFDARGRQTHRLAVGGRQPSCPAFGGPEF
DRLLVTTATEGMEDPGPGEGLPYLLRPGLRGLAEPRVTL

Sequences:

>Translated_279_residues
MSWEVFDPRVCGLGEGPLWHPERQQFLWFDILGRRLLGEGGAAWTFDRAVTAAGWIDRDRLLVATETGLAVLDLQRRTLD
PLLAVEADRPETRSNDGRADRQGGFWFGTMGKEAQSGAGSLYRYHRGRIERLVEGLTIPNAICFSPDGRTAYYSDTDRQL
VWTQRLDAEGWPVGERELFLDLADEGLNPDGAVIDAEGGFCCAAWGAGAVLRFDARGRQTHRLAVGGRQPSCPAFGGPEF
DRLLVTTATEGMEDPGPGEGLPYLLRPGLRGLAEPRVTL
>Mature_278_residues
SWEVFDPRVCGLGEGPLWHPERQQFLWFDILGRRLLGEGGAAWTFDRAVTAAGWIDRDRLLVATETGLAVLDLQRRTLDP
LLAVEADRPETRSNDGRADRQGGFWFGTMGKEAQSGAGSLYRYHRGRIERLVEGLTIPNAICFSPDGRTAYYSDTDRQLV
WTQRLDAEGWPVGERELFLDLADEGLNPDGAVIDAEGGFCCAAWGAGAVLRFDARGRQTHRLAVGGRQPSCPAFGGPEFD
RLLVTTATEGMEDPGPGEGLPYLLRPGLRGLAEPRVTL

Specific function: Unknown

COG id: COG3386

COG function: function code G; Gluconolactonase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SMP-30/CGR1 family [H]

Homologues:

Organism=Homo sapiens, GI23111021, Length=270, Percent_Identity=25.9259259259259, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4759036, Length=270, Percent_Identity=25.9259259259259, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641471, Length=307, Percent_Identity=27.0358306188925, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI18860103, Length=307, Percent_Identity=27.0358306188925, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641469, Length=307, Percent_Identity=27.0358306188925, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45551448, Length=307, Percent_Identity=27.0358306188925, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646912, Length=286, Percent_Identity=25.8741258741259, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24646910, Length=286, Percent_Identity=25.8741258741259, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR013658
- InterPro:   IPR005511 [H]

Pfam domain/function: PF08450 SGL [H]

EC number: 3.1.1.17

Molecular weight: Translated: 30672; Mature: 30541

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWEVFDPRVCGLGEGPLWHPERQQFLWFDILGRRLLGEGGAAWTFDRAVTAAGWIDRDR
CCCCCCCCEECCCCCCCCCCCCHHHEEHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCC
LLVATETGLAVLDLQRRTLDPLLAVEADRPETRSNDGRADRQGGFWFGTMGKEAQSGAGS
EEEEECCCEEEEEEHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHH
LYRYHRGRIERLVEGLTIPNAICFSPDGRTAYYSDTDRQLVWTQRLDAEGWPVGERELFL
HHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCCEEEEEEECCCCCCCCCCHHEEE
DLADEGLNPDGAVIDAEGGFCCAAWGAGAVLRFDARGRQTHRLAVGGRQPSCPAFGGPEF
EEHHCCCCCCCCEEECCCCEEEEECCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCC
DRLLVTTATEGMEDPGPGEGLPYLLRPGLRGLAEPRVTL
CEEEEEEECCCCCCCCCCCCCCHHHCCCCHHCCCCCCCC
>Mature Secondary Structure 
SWEVFDPRVCGLGEGPLWHPERQQFLWFDILGRRLLGEGGAAWTFDRAVTAAGWIDRDR
CCCCCCCEECCCCCCCCCCCCHHHEEHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCC
LLVATETGLAVLDLQRRTLDPLLAVEADRPETRSNDGRADRQGGFWFGTMGKEAQSGAGS
EEEEECCCEEEEEEHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHH
LYRYHRGRIERLVEGLTIPNAICFSPDGRTAYYSDTDRQLVWTQRLDAEGWPVGERELFL
HHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCCEEEEEEECCCCCCCCCCHHEEE
DLADEGLNPDGAVIDAEGGFCCAAWGAGAVLRFDARGRQTHRLAVGGRQPSCPAFGGPEF
EEHHCCCCCCCCEEECCCCEEEEECCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCC
DRLLVTTATEGMEDPGPGEGLPYLLRPGLRGLAEPRVTL
CEEEEEEECCCCCCCCCCCCCCHHHCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glucono-1,5-lactone; H2O

Specific reaction: D-glucono-1,5-lactone + H2O = D-gluconate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA