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The map label for this gene is arsC [H]

Identifier: 77465140

GI number: 77465140

Start: 171367

End: 171798

Strand: Direct

Name: arsC [H]

Synonym: RSP_3127

Alternate gene names: 77465140

Gene position: 171367-171798 (Clockwise)

Preceding gene: 77465139

Following gene: 77465142

Centisome position: 18.17

GC content: 68.29

Gene sequence:

>432_bases
ATGATCGTCATCCACCACAACCCTGCCTGCGGCACGTCGCGCAACGTGCTGGAGATCATCCGCGCGTCCGGCGCCGAGCC
GGTCATCATCGACTATCTGGCCGAAGGCTGGACACGTCCGCAGCTGCTGGCTCTGCTGGCCGCGGCCGATCTGACGCCGC
GTCAGGCGCTGCGGACGTCGAAGTCGCCCGCCGCCGAACTGGGCCTGTTGGAGGCTGGCGTCACCGACGGGCAGATCCTC
GATGCAATGCTCGCCCATCCGGTGCTGGTCAACCGGCCCATCGTGGCCTCGCCCAGGGGCGTGCGGCTCTGTCGCCCGTC
CGAGACCGTGCTGTCGCTTCTGGACCGCCTGCCGGTTGGGCCGCTCTACAAGGAGGACGGGCAGATGATCCTGAACGAGA
GGGGCGAGATCGTCAGCGACCTGCCCACCTGA

Upstream 100 bases:

>100_bases
CGCTGGCAACGGTCGTGGGCGTTCTGGTCGAGGTGCCGGTGATGCTGTCCCTCGTGGCCTTCGCCAACCGCACCCGCGCC
CGTTTCCCGGAGATCCGCGC

Downstream 100 bases:

>100_bases
ACCCCGACCGACCTGCGAGCATCGATCGGAGCGCCTCGCCCTCATGGTGATGCGCACCGGCACGTCGGCGAGGCAGGCCT
GCAGGTCGAGGCCGCTCGGG

Product: putative arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MIVIHHNPACGTSRNVLEIIRASGAEPVIIDYLAEGWTRPQLLALLAAADLTPRQALRTSKSPAAELGLLEAGVTDGQIL
DAMLAHPVLVNRPIVASPRGVRLCRPSETVLSLLDRLPVGPLYKEDGQMILNERGEIVSDLPT

Sequences:

>Translated_143_residues
MIVIHHNPACGTSRNVLEIIRASGAEPVIIDYLAEGWTRPQLLALLAAADLTPRQALRTSKSPAAELGLLEAGVTDGQIL
DAMLAHPVLVNRPIVASPRGVRLCRPSETVLSLLDRLPVGPLYKEDGQMILNERGEIVSDLPT
>Mature_143_residues
MIVIHHNPACGTSRNVLEIIRASGAEPVIIDYLAEGWTRPQLLALLAAADLTPRQALRTSKSPAAELGLLEAGVTDGQIL
DAMLAHPVLVNRPIVASPRGVRLCRPSETVLSLLDRLPVGPLYKEDGQMILNERGEIVSDLPT

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=135, Percent_Identity=51.8518518518518, Blast_Score=142, Evalue=6e-36,
Organism=Escherichia coli, GI1788841, Length=116, Percent_Identity=31.8965517241379, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 15371; Mature: 15371

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVIHHNPACGTSRNVLEIIRASGAEPVIIDYLAEGWTRPQLLALLAAADLTPRQALRTS
CEEEECCCCCCCCHHHHHHHHHCCCCCEEHHHHHCCCCCHHHHHHHHHCCCCHHHHHHCC
KSPAAELGLLEAGVTDGQILDAMLAHPVLVNRPIVASPRGVRLCRPSETVLSLLDRLPVG
CCCHHHHHHHHCCCCCHHHHHHHHHCCHHHCCCCEECCCCCEEECCHHHHHHHHHHCCCC
PLYKEDGQMILNERGEIVSDLPT
CCCCCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure
MIVIHHNPACGTSRNVLEIIRASGAEPVIIDYLAEGWTRPQLLALLAAADLTPRQALRTS
CEEEECCCCCCCCHHHHHHHHHCCCCCEEHHHHHCCCCCHHHHHHHHHCCCCHHHHHHCC
KSPAAELGLLEAGVTDGQILDAMLAHPVLVNRPIVASPRGVRLCRPSETVLSLLDRLPVG
CCCHHHHHHHHCCCCCHHHHHHHHHCCHHHCCCCEECCCCCEEECCHHHHHHHHHHCCCC
PLYKEDGQMILNERGEIVSDLPT
CCCCCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]