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The map label for this gene is 77465139

Identifier: 77465139

GI number: 77465139

Start: 170318

End: 171370

Strand: Direct

Name: 77465139

Synonym: RSP_3126

Alternate gene names: NA

Gene position: 170318-171370 (Clockwise)

Preceding gene: 77465138

Following gene: 77465140

Centisome position: 18.06

GC content: 66.57

Gene sequence:

>1053_bases
ATGACCGACCTGCCGCAGACCCAGATCAATCCCCTGGGCCCGTTCGAGCGCTGGCTGACCCTCTGGGTCGGGCTGGCCAT
GGTGGCGGGCCTCTCCCTGGGCGTGCTGGCTCCGGGTCTGGTGCAGGTCATCGCCACGGCCGAGATCGCCTCGATCAACC
TCGTCGTCGCCGTGCTGATCTGGGCGATGGTCTATCCGATGATGGTCAACGTGGATTTCGCCGCCGTCGGGGGGGCTGTG
CGGCAGCCGACAGGACTGCTCATCACGCTAGTCGTCAACTGGCTGGTCAAGCCCTTCACCATGGCTCTGCTGGCGGTCCT
GTTCTTCGACCTTGTCTTCGCTCCCTGGATCGCCCCCGAGGATGCGCAGCAGTATATCGCCGGTCTGATCCTGCTGGGCG
CCGCGCCCTGCACCGCGATGGTCTTCGTCTGGTCCCAACTGGTGCGCGGTGATGCGACCTACACGCTGGTGCAGGTGTCG
GTAAACGACATGGTGATGGTCGTGGCCTTCGCCCCCATCGTGGCCCTGCTTCTCGGCGTGACCGAGATCGTCGTGCCCTG
GCAGACGCTGGTCCTGGCGACGATCCTCTATGTCGTCCTGCCGCTGGCGGCAGGGATGCTGACGCGCCGCAGTCTTGGCA
CCCCCGCCCGGATCGAGGCGTTCTCGGCCCGCGTGAAGCCCTGGTCGATGATCGGCCTGATCGCGACGGTCGCGATCCTC
TTCGGGCTGCAGGGGCAGACGATCCTCGACCGGCCCGCGATCATTGCGCTGATCGCCGTGCCGATCCTGATCCAGAGCTA
TCTGATCTTTGCCGTGGGTTACGGCGCGGCCTGGCTGATGAGGGTGCCGCACCGGATCGCGGCGCCGTGCGCCATGATCG
GCACCTCGAACTTCTTCGAACTGGCCGTCGCCGTCGCCATCAGTCTCTTCGGCCTCAATTCGGGCGCGGCGCTGGCAACG
GTCGTGGGCGTTCTGGTCGAGGTGCCGGTGATGCTGTCCCTCGTGGCCTTCGCCAACCGCACCCGCGCCCGTTTCCCGGA
GATCCGCGCATGA

Upstream 100 bases:

>100_bases
ATTGCTGCGGCGGCCGTCCCGAGCTCTGTCAGCCGGTTCTCGACCGGATCGCCTGCGACTGCTGAGTGCACGCATAACCC
TGCCCAGAGGCTGAACCAAG

Downstream 100 bases:

>100_bases
TCGTCATCCACCACAACCCTGCCTGCGGCACGTCGCGCAACGTGCTGGAGATCATCCGCGCGTCCGGCGCCGAGCCGGTC
ATCATCGACTATCTGGCCGA

Product: ACR3 family arsenite efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTDLPQTQINPLGPFERWLTLWVGLAMVAGLSLGVLAPGLVQVIATAEIASINLVVAVLIWAMVYPMMVNVDFAAVGGAV
RQPTGLLITLVVNWLVKPFTMALLAVLFFDLVFAPWIAPEDAQQYIAGLILLGAAPCTAMVFVWSQLVRGDATYTLVQVS
VNDMVMVVAFAPIVALLLGVTEIVVPWQTLVLATILYVVLPLAAGMLTRRSLGTPARIEAFSARVKPWSMIGLIATVAIL
FGLQGQTILDRPAIIALIAVPILIQSYLIFAVGYGAAWLMRVPHRIAAPCAMIGTSNFFELAVAVAISLFGLNSGAALAT
VVGVLVEVPVMLSLVAFANRTRARFPEIRA

Sequences:

>Translated_350_residues
MTDLPQTQINPLGPFERWLTLWVGLAMVAGLSLGVLAPGLVQVIATAEIASINLVVAVLIWAMVYPMMVNVDFAAVGGAV
RQPTGLLITLVVNWLVKPFTMALLAVLFFDLVFAPWIAPEDAQQYIAGLILLGAAPCTAMVFVWSQLVRGDATYTLVQVS
VNDMVMVVAFAPIVALLLGVTEIVVPWQTLVLATILYVVLPLAAGMLTRRSLGTPARIEAFSARVKPWSMIGLIATVAIL
FGLQGQTILDRPAIIALIAVPILIQSYLIFAVGYGAAWLMRVPHRIAAPCAMIGTSNFFELAVAVAISLFGLNSGAALAT
VVGVLVEVPVMLSLVAFANRTRARFPEIRA
>Mature_349_residues
TDLPQTQINPLGPFERWLTLWVGLAMVAGLSLGVLAPGLVQVIATAEIASINLVVAVLIWAMVYPMMVNVDFAAVGGAVR
QPTGLLITLVVNWLVKPFTMALLAVLFFDLVFAPWIAPEDAQQYIAGLILLGAAPCTAMVFVWSQLVRGDATYTLVQVSV
NDMVMVVAFAPIVALLLGVTEIVVPWQTLVLATILYVVLPLAAGMLTRRSLGTPARIEAFSARVKPWSMIGLIATVAILF
GLQGQTILDRPAIIALIAVPILIQSYLIFAVGYGAAWLMRVPHRIAAPCAMIGTSNFFELAVAVAISLFGLNSGAALATV
VGVLVEVPVMLSLVAFANRTRARFPEIRA

Specific function: Unknown

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=288, Percent_Identity=28.125, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 37343; Mature: 37211

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLPQTQINPLGPFERWLTLWVGLAMVAGLSLGVLAPGLVQVIATAEIASINLVVAVLI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WAMVYPMMVNVDFAAVGGAVRQPTGLLITLVVNWLVKPFTMALLAVLFFDLVFAPWIAPE
HHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
DAQQYIAGLILLGAAPCTAMVFVWSQLVRGDATYTLVQVSVNDMVMVVAFAPIVALLLGV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHH
TEIVVPWQTLVLATILYVVLPLAAGMLTRRSLGTPARIEAFSARVKPWSMIGLIATVAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
FGLQGQTILDRPAIIALIAVPILIQSYLIFAVGYGAAWLMRVPHRIAAPCAMIGTSNFFE
HCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHCCCHHHH
LAVAVAISLFGLNSGAALATVVGVLVEVPVMLSLVAFANRTRARFPEIRA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDLPQTQINPLGPFERWLTLWVGLAMVAGLSLGVLAPGLVQVIATAEIASINLVVAVLI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WAMVYPMMVNVDFAAVGGAVRQPTGLLITLVVNWLVKPFTMALLAVLFFDLVFAPWIAPE
HHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
DAQQYIAGLILLGAAPCTAMVFVWSQLVRGDATYTLVQVSVNDMVMVVAFAPIVALLLGV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHH
TEIVVPWQTLVLATILYVVLPLAAGMLTRRSLGTPARIEAFSARVKPWSMIGLIATVAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
FGLQGQTILDRPAIIALIAVPILIQSYLIFAVGYGAAWLMRVPHRIAAPCAMIGTSNFFE
HCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHCCCHHHH
LAVAVAISLFGLNSGAALATVVGVLVEVPVMLSLVAFANRTRARFPEIRA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]