Click here to switch to the map view.

The map label for this gene is 77465118

Identifier: 77465118

GI number: 77465118

Start: 149100

End: 151286

Strand: Reverse

Name: 77465118

Synonym: RSP_3105

Alternate gene names: NA

Gene position: 151286-149100 (Counterclockwise)

Preceding gene: 77465119

Following gene: 77465115

Centisome position: 16.04

GC content: 71.38

Gene sequence:

>2187_bases
ATGGCCCAAGGCACCGTTGAAGCTCGTCACGGAGCTCTGGACGAAGCTGCGCTGGGGATCGGACGCTGGCGCTGGGACCT
CCGGTCTCAGGAGCTGGTCTGGTCCGAGGAGGAGCGGGCGATCTTCGGCCTTGCGCCGGGCGCGCCGGTTCCGGGTTTTG
CCGCCTTCAGCGCCATGATCCACCCGGACGACCGCGCCCGCGTGGTGGCCGCGGTCAGCGAGACGCTGGCGCAACGCCGC
CTCCGCCACAGCATCGGCTTCCGCATCCTGCGCCCCGACGGGACGATGCGCCAGATCCTCAGCCACGGGCGGCTCGTGAT
GGGGCTGGACGGCAAGCCGATCAGTCTCGAGGGGGTGGATCTCGACCTCACCGATACGCAGGCCGACCCGGCGCTCGAAC
GGCCGCAGCGCGCGCCCTGCCCGGACAAGAGCCCGCACATTGCGGCGCTCCGCCCCGGGGAGGAGCAGGATGCGCTGCTG
CGGGTGGCGCTGGAGGCCGGCCGGATGACCGTCTGGCAGCTCGACCTGCAGAAGCGGCTGGTGCAGGTCGACGGCGACGT
GGCGCGCCTGATCGGCCTGAGCCATGTGCCGCCGGAACTGCCGGTCGCCGTTTTCGAGAATTACGTCGATCCCGAGGATC
TGCCGCTCCTGCGCGCGGCCGAGGCTGCGGCTCTGCGCGGCGAGCCCATGCAGGTGGAGCTGCGGCTCGTGCTGGAGAGC
GGCGGGCGGCGCTGGCTGCGGCTGATGGGCGAGCCGCGGCCCGATGCCATGGGCCGTCCGCAGCGCCTCGTGGGCGTGGC
CTACGACATCTCCGCGCGCAAGGAGGCCGAGGAGAAGCTCCGGGAAAGCGAAGCGCATTACCGCGCCGTGTTCGCCGCCA
TCGACGAGGGCTTCTGCACCTGCGAGATGATCGTGGACGAGACGGGCGCCCCGGTCGACTATCGCTTCCTCGAGGCGAAC
CCGCTGTTCGAAAGCATGACCGGTCTCGTCAATGCCGTCGGGCGCACCGCGCTCGAGCTGGTGCCGAACCTCGAGCGGCA
CTGGATCGAGATCTATGCCCGCGTGGGGCTGGGGGGCGAGACGCTGCGGTTCGAGCTGCCGTCGGATGCGATGGGCCGCT
GGTTCAACGTCTTTGCCGCGCCGCTCGCAGCCCCCGGGCGGTTCGCGCTCGTGTTCAAGGATGTGACCGACCGCCGCCGC
AGCGAGGAAGCGCTGCGCGAGAGCGAGGCGATGTTCCGCTCGCTCACCGAGGCCATGCCGCAGCTGGTCTGGTCCGCGCG
GCCGGACGGCTCGTGCGACTTCTTCAACCGCCGCTGGACCGACTGCACCGGGGCCAGCACCGAGATGGCGATGGGCGACG
GATGGCGGGCCTTCTACCACCCCGACGACCAGCCGGCCATCGACCGGCTCTGGCCGAAGGCCCTGCGCACGGGCGAGCAC
TACGAGATCGAATACCGGCTCCGCCACCGCGACGGCAGCTACCGCTGGATGCTCGGCCGCGGCGTGCCCGTGCGCGACGA
GGCGGGCGGGATCCTGCGTTGGATGGGCACCTGCACCGACATTCACGACCTGAAGCTCGCCCATCAGCGCCAGCAGATCC
TGCTGGGCGAGATGGAGCACCGCGTGAAGAACATCCTCGCGCTGGTGCAGGCGGTGGCGCGGCAGACCTTCGGCCGCATT
CCCGAGGCATCGAGCGCGCTGGAGGCCTACGGCGGGCGGCTGCAGTCGCTGGCCGGCGCCTACAGCCACCTCAACCACGA
GAACTGGGAGCGGGCCTCGCTCCGCCACATCGTCGCGACCTCGATCGGCGGCTGCGGCGCGCGGGCCGAAGCCTGGAGCC
TCGACGGGCCCGAGGTGATGCTGCCCCCGCGCTCGGCGGTCCCCGTCTCGATGGCGGTGCATGAGCTCTGCACCAATGCG
GTGAAATACGGCGCGCTCTCGGTGCCCGAGGGCCGGGTGACGATCCACTGGAGCCTCGGACCGGGAGACCGCCTCACGCT
CGTCTGGGCGGAGGCGGACGGCCCGCATGTGGTGCCGCCTGCGCGCGCGGGCTTCGGGATGCGCATGATCGAGACGGTGC
TGGCGGTCGAGGCGGGAGGCACCGTCCGGCTCGACTTCCGCCCCGAAGGGGTACGCTGCGAGATCGAGGTGCCCATCCGC
CCCGAGCCCGGGCTGCGGGTGGAGTGA

Upstream 100 bases:

>100_bases
ACAGCAAAGTTGGAGTTGCGAAATCGGAGCCGGGGATCATATTGGTAGTTCGAGCGCCGGGGCAGTCGAGCCTCCGCGCG
GTCTGACGAGAATGGAGACG

Downstream 100 bases:

>100_bases
AGCGGGCGGCTGCGCCGCCCGCCTTCCGTCAGGCGCCGGTCAGGCCCGGCTTCAGCACCACCTTGGTCCACTCGTTCTGG
TTGAAGCGGAAGTTCTCGTA

Product: PAS sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 728; Mature: 727

Protein sequence:

>728_residues
MAQGTVEARHGALDEAALGIGRWRWDLRSQELVWSEEERAIFGLAPGAPVPGFAAFSAMIHPDDRARVVAAVSETLAQRR
LRHSIGFRILRPDGTMRQILSHGRLVMGLDGKPISLEGVDLDLTDTQADPALERPQRAPCPDKSPHIAALRPGEEQDALL
RVALEAGRMTVWQLDLQKRLVQVDGDVARLIGLSHVPPELPVAVFENYVDPEDLPLLRAAEAAALRGEPMQVELRLVLES
GGRRWLRLMGEPRPDAMGRPQRLVGVAYDISARKEAEEKLRESEAHYRAVFAAIDEGFCTCEMIVDETGAPVDYRFLEAN
PLFESMTGLVNAVGRTALELVPNLERHWIEIYARVGLGGETLRFELPSDAMGRWFNVFAAPLAAPGRFALVFKDVTDRRR
SEEALRESEAMFRSLTEAMPQLVWSARPDGSCDFFNRRWTDCTGASTEMAMGDGWRAFYHPDDQPAIDRLWPKALRTGEH
YEIEYRLRHRDGSYRWMLGRGVPVRDEAGGILRWMGTCTDIHDLKLAHQRQQILLGEMEHRVKNILALVQAVARQTFGRI
PEASSALEAYGGRLQSLAGAYSHLNHENWERASLRHIVATSIGGCGARAEAWSLDGPEVMLPPRSAVPVSMAVHELCTNA
VKYGALSVPEGRVTIHWSLGPGDRLTLVWAEADGPHVVPPARAGFGMRMIETVLAVEAGGTVRLDFRPEGVRCEIEVPIR
PEPGLRVE

Sequences:

>Translated_728_residues
MAQGTVEARHGALDEAALGIGRWRWDLRSQELVWSEEERAIFGLAPGAPVPGFAAFSAMIHPDDRARVVAAVSETLAQRR
LRHSIGFRILRPDGTMRQILSHGRLVMGLDGKPISLEGVDLDLTDTQADPALERPQRAPCPDKSPHIAALRPGEEQDALL
RVALEAGRMTVWQLDLQKRLVQVDGDVARLIGLSHVPPELPVAVFENYVDPEDLPLLRAAEAAALRGEPMQVELRLVLES
GGRRWLRLMGEPRPDAMGRPQRLVGVAYDISARKEAEEKLRESEAHYRAVFAAIDEGFCTCEMIVDETGAPVDYRFLEAN
PLFESMTGLVNAVGRTALELVPNLERHWIEIYARVGLGGETLRFELPSDAMGRWFNVFAAPLAAPGRFALVFKDVTDRRR
SEEALRESEAMFRSLTEAMPQLVWSARPDGSCDFFNRRWTDCTGASTEMAMGDGWRAFYHPDDQPAIDRLWPKALRTGEH
YEIEYRLRHRDGSYRWMLGRGVPVRDEAGGILRWMGTCTDIHDLKLAHQRQQILLGEMEHRVKNILALVQAVARQTFGRI
PEASSALEAYGGRLQSLAGAYSHLNHENWERASLRHIVATSIGGCGARAEAWSLDGPEVMLPPRSAVPVSMAVHELCTNA
VKYGALSVPEGRVTIHWSLGPGDRLTLVWAEADGPHVVPPARAGFGMRMIETVLAVEAGGTVRLDFRPEGVRCEIEVPIR
PEPGLRVE
>Mature_727_residues
AQGTVEARHGALDEAALGIGRWRWDLRSQELVWSEEERAIFGLAPGAPVPGFAAFSAMIHPDDRARVVAAVSETLAQRRL
RHSIGFRILRPDGTMRQILSHGRLVMGLDGKPISLEGVDLDLTDTQADPALERPQRAPCPDKSPHIAALRPGEEQDALLR
VALEAGRMTVWQLDLQKRLVQVDGDVARLIGLSHVPPELPVAVFENYVDPEDLPLLRAAEAAALRGEPMQVELRLVLESG
GRRWLRLMGEPRPDAMGRPQRLVGVAYDISARKEAEEKLRESEAHYRAVFAAIDEGFCTCEMIVDETGAPVDYRFLEANP
LFESMTGLVNAVGRTALELVPNLERHWIEIYARVGLGGETLRFELPSDAMGRWFNVFAAPLAAPGRFALVFKDVTDRRRS
EEALRESEAMFRSLTEAMPQLVWSARPDGSCDFFNRRWTDCTGASTEMAMGDGWRAFYHPDDQPAIDRLWPKALRTGEHY
EIEYRLRHRDGSYRWMLGRGVPVRDEAGGILRWMGTCTDIHDLKLAHQRQQILLGEMEHRVKNILALVQAVARQTFGRIP
EASSALEAYGGRLQSLAGAYSHLNHENWERASLRHIVATSIGGCGARAEAWSLDGPEVMLPPRSAVPVSMAVHELCTNAV
KYGALSVPEGRVTIHWSLGPGDRLTLVWAEADGPHVVPPARAGFGMRMIETVLAVEAGGTVRLDFRPEGVRCEIEVPIRP
EPGLRVE

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light. Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection o

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80866; Mature: 80735

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50112 PAS ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQGTVEARHGALDEAALGIGRWRWDLRSQELVWSEEERAIFGLAPGAPVPGFAAFSAMI
CCCCCCHHHCCCHHHHHHCCHHEEECCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHEEE
HPDDRARVVAAVSETLAQRRLRHSIGFRILRPDGTMRQILSHGRLVMGLDGKPISLEGVD
CCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHCCCEEEECCCCCEEEECCE
LDLTDTQADPALERPQRAPCPDKSPHIAALRPGEEQDALLRVALEAGRMTVWQLDLQKRL
EECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEEHHHHH
VQVDGDVARLIGLSHVPPELPVAVFENYVDPEDLPLLRAAEAAALRGEPMQVELRLVLES
HHCCCHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECC
GGRRWLRLMGEPRPDAMGRPQRLVGVAYDISARKEAEEKLRESEAHYRAVFAAIDEGFCT
CCHHHHHHCCCCCCCCCCCCHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
CEMIVDETGAPVDYRFLEANPLFESMTGLVNAVGRTALELVPNLERHWIEIYARVGLGGE
EEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
TLRFELPSDAMGRWFNVFAAPLAAPGRFALVFKDVTDRRRSEEALRESEAMFRSLTEAMP
EEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVWSARPDGSCDFFNRRWTDCTGASTEMAMGDGWRAFYHPDDQPAIDRLWPKALRTGEH
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCHHHHHHHHHHCCCCC
YEIEYRLRHRDGSYRWMLGRGVPVRDEAGGILRWMGTCTDIHDLKLAHQRQQILLGEMEH
EEEEEEEEECCCCEEEEECCCCCCCCCCCCCEEEHHCCCCHHHHHHHHHHHHHHHHHHHH
RVKNILALVQAVARQTFGRIPEASSALEAYGGRLQSLAGAYSHLNHENWERASLRHIVAT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
SIGGCGARAEAWSLDGPEVMLPPRSAVPVSMAVHELCTNAVKYGALSVPEGRVTIHWSLG
CCCCCCCCCCEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCEECCCCEEEEEEECC
PGDRLTLVWAEADGPHVVPPARAGFGMRMIETVLAVEAGGTVRLDFRPEGVRCEIEVPIR
CCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHEECCCEEEEEECCCCEEEEEEECCC
PEPGLRVE
CCCCCCCC
>Mature Secondary Structure 
AQGTVEARHGALDEAALGIGRWRWDLRSQELVWSEEERAIFGLAPGAPVPGFAAFSAMI
CCCCCHHHCCCHHHHHHCCHHEEECCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHEEE
HPDDRARVVAAVSETLAQRRLRHSIGFRILRPDGTMRQILSHGRLVMGLDGKPISLEGVD
CCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHCCCEEEECCCCCEEEECCE
LDLTDTQADPALERPQRAPCPDKSPHIAALRPGEEQDALLRVALEAGRMTVWQLDLQKRL
EECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEEHHHHH
VQVDGDVARLIGLSHVPPELPVAVFENYVDPEDLPLLRAAEAAALRGEPMQVELRLVLES
HHCCCHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECC
GGRRWLRLMGEPRPDAMGRPQRLVGVAYDISARKEAEEKLRESEAHYRAVFAAIDEGFCT
CCHHHHHHCCCCCCCCCCCCHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
CEMIVDETGAPVDYRFLEANPLFESMTGLVNAVGRTALELVPNLERHWIEIYARVGLGGE
EEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
TLRFELPSDAMGRWFNVFAAPLAAPGRFALVFKDVTDRRRSEEALRESEAMFRSLTEAMP
EEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVWSARPDGSCDFFNRRWTDCTGASTEMAMGDGWRAFYHPDDQPAIDRLWPKALRTGEH
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCHHHHHHHHHHCCCCC
YEIEYRLRHRDGSYRWMLGRGVPVRDEAGGILRWMGTCTDIHDLKLAHQRQQILLGEMEH
EEEEEEEEECCCCEEEEECCCCCCCCCCCCCEEEHHCCCCHHHHHHHHHHHHHHHHHHHH
RVKNILALVQAVARQTFGRIPEASSALEAYGGRLQSLAGAYSHLNHENWERASLRHIVAT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
SIGGCGARAEAWSLDGPEVMLPPRSAVPVSMAVHELCTNAVKYGALSVPEGRVTIHWSLG
CCCCCCCCCCEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCEECCCCEEEEEEECC
PGDRLTLVWAEADGPHVVPPARAGFGMRMIETVLAVEAGGTVRLDFRPEGVRCEIEVPIR
CCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHEECCCEEEEEECCCCEEEEEEECCC
PEPGLRVE
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA