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The map label for this gene is qoxA [H]

Identifier: 77465111

GI number: 77465111

Start: 139419

End: 141896

Strand: Reverse

Name: qoxA [H]

Synonym: RSP_3097

Alternate gene names: 77465111

Gene position: 141896-139419 (Counterclockwise)

Preceding gene: 77465112

Following gene: 77465110

Centisome position: 15.05

GC content: 69.33

Gene sequence:

>2478_bases
ATGAATGCCCTGCGCCGACACCGCCTCCTCACGCGGATCTGGGCCTCCGAGCCCGGCTGGCGCGGCTGGTTCACCACCGT
GAACCACACCGATCTTGGCCGGATGTTCCTCGGCGCGTCGGTCGTCTTCTTCCTGATCGGCGGCATCCTCGCCATGCTGA
TCCGGGCGCAGCTGGCCAGCCCCCGCTCGGCCTTCGTGGGCGCCGAGACCTATGCGCAGCTCTTCACGATGCACGGGACC
ATCATGATGTTCCTGTTCGCGATCCCGATGTTCGAGGGGCTCACGATCTATCTGCTGCCGAAGATGCTGGGGTCGCGGGA
TCTGGCCTATCCGCGGCTCTCGGCTTACGGTTTCTGGTGCTATGTGCTGGGCGGCTCGATGCTGATCGTGGCGCTGCTGG
CCGGGATCGCGCCCGACAGCGGCTGGTTCATGTATCCGCCGCTGGCCTCGACGCTGGGCTCGCCCGGGATCAATTCCGAT
TTCTGGCTTCTGGGCATCACCTTCGTCGAGATCTCGGCCATCGCGGCCGCGGTCGAGATCGTGGTGACGGTGCTGCGCTT
CCGCGCCCCCGGCATGTCGCTCGACCGGATGCCGATCTATGGCTGGTATGCGCTCGTCACGGCGACGATGATCCTCACGG
GCTTTCCGCCGCTGATCCTCGGCTCGATCCTTCTGGAACTGGAGCGCGCCTTCGGCCTGCCCTTCTTCCAGGTGGCCGAG
GGGGGCGACAGCCTGCTCTGGCAGCACCTCTTCTGGCTCTTCGGCCATCCCGAGGTCTATATCATCTTCCTGCCCGCCGC
GGGGGCGATCTCGACCATCCTGCCCGTGATGGCGCGAACCGAGCTCATCGGCTATCGCTGGGTGGTGGCCGCCGCCATCT
CGCTCGCGGTGCTGAGCTTCGGGCTCTGGGTCCACCACATGTTCACGACCGGCATCCCCCACATGGGGCTTGCGCTCTTC
TCGGCCGCCTCGACGCTCGTTGCGGTGCCGACGGCGGTGCAGCTCTTCGCCTGGATCGGCACGCTCTGGCGCGGCACGCC
CGAGATGCGGCTGCCGATGATGTGGATCCTCGCCTTCTTCGCCACCTTCGTGATCGGCGGGCTGACCGGCGTCATGGTGG
CGGTGGTGCCCTTCGACTGGCAGGTGCATGACACGCATTTCATCGTGGCCCACCTCCACTACGTCCTCGTCGGCGGCTTC
GTCTTCCCGATGCTCGCCGCGCTCTACTACTGGATGCCCCATGTCACCGGGCGGAAGCGGTTCTTCCGGGTGGGCGACGT
GGCCTTCTGGCTGGTGACGGTGGGCTTTCACGCCACGTTCCTCGCCGTCCACTGGGTAGGGCTCCTCGGCCAGCGGCGGC
GGACCGAGACCTACGAGCCCGGCCAGGGATGGGAGGTCATCAACCTCATCTCCTCGATCGGCGGCTTCGTCATGGCGATC
GGCTTCGCGCTGGTGATCCTCGACGTGGCGATGAACGCGCTGGTGGCCGTCCGGGGCAGCCGCAATCCCTGGCGCGCGGG
CACGCTCGAATGGGCGATGCCCACGCCCGCGCCCGCCTACAATTTCGCGAGCCTGCCGGAGGTGAGCGGCCGCGATCCGC
TCCATGCCGATCCCGACCTCGCGGTGAAGATCGCCAGGGGCGCCTTCTACCTGGGCGAGCCCCGCAACGGGAGGCGCGAG
ACGCTGATGGTGAATGTGGCGACCGGGCGGCCCGCGAGCCTCGTCGTCTATCCCGGCAACAGCGCCCTTCCCTTTCAGCT
CGCGCTCGTGACCGGGCTCTTCTTCCTGGGGATGCTCCTGAAGACCTACTGGCTGGTGCCGCTGGCGCTGGTCGGTGTGG
CGGCGCTGGCCATCCGCTGGGTCTGGACCAATGCGCCCGGGCGCGACGAGGGTCCGCAGCCGGTGGGCCTCGGCCTCAGC
CTGCCCCGCGACGTGGCGCAGAGCCCCGGCTGGTGGGGGTCGCTCTTCCTCTTGCTGGCGAACGGCACGCTCTTCGGCTC
GCTCATGTTCGGCTATGCCTTCCTCTGGACGGTGGCGCCGAACTGGCCGCCGCCCGCATGGCTCGCGCCCTCGGGGCTGC
AGGGCGCGCTCCTCCTCGCGGGGGCGGCGAGTGCGCCCCTCCTCGTGCGGCTGGCGGACCGCACACTCCGGCGGGGAGGC
TCGCCGCAGGCGGGGCTTGCGGGGGCGGCACTGGCGCTCGGGGCACTTGCCGCGGCGGCGGGGATGCTCTGCCTCGCCCT
GCCTGCGCCGCAGCGGCATGCCTATGACGCGACCGTCTGGGTCATCGCGGGCTATACGGGGTTTCATGCAGGCCTGGCCC
TCCTGATGACGCTGGTCGTGATGGCGATGCAGGCCCGCGGCAGGCTCTCGGCCGCGCGGATCTCGCCCTTGCGCATCCTC
CGGCTCTGGACCGACTGGGCGGCCTTCGCGGGCCTCGTCGGCGTTGCCGCCGCCCTCCTGCCGGGGCTCGTGGCATGA

Upstream 100 bases:

>100_bases
TCAGCGCCGAATTCAGCGGACCCGGCTACCGCACCCACGCCTTCACGGTCCGCGCGCACGATGCCGCCGACTGGCAGGCC
TTCCTCGAGGCTCCCTCTCC

Downstream 100 bases:

>100_bases
GCGCCATCCTCCGCATCGCCTTGCCCCTCACGCTCTGGCTCGCGGGCTTCAGCGCGGTCTACGCCCTGCATGGCCTCGTC
TGCTCTGGCGGCTGGCCCGG

Product: QoxA, quinol oxidase subunit I

Products: NA

Alternate protein names: Caa-3605 subunit 1; Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 825; Mature: 825

Protein sequence:

>825_residues
MNALRRHRLLTRIWASEPGWRGWFTTVNHTDLGRMFLGASVVFFLIGGILAMLIRAQLASPRSAFVGAETYAQLFTMHGT
IMMFLFAIPMFEGLTIYLLPKMLGSRDLAYPRLSAYGFWCYVLGGSMLIVALLAGIAPDSGWFMYPPLASTLGSPGINSD
FWLLGITFVEISAIAAAVEIVVTVLRFRAPGMSLDRMPIYGWYALVTATMILTGFPPLILGSILLELERAFGLPFFQVAE
GGDSLLWQHLFWLFGHPEVYIIFLPAAGAISTILPVMARTELIGYRWVVAAAISLAVLSFGLWVHHMFTTGIPHMGLALF
SAASTLVAVPTAVQLFAWIGTLWRGTPEMRLPMMWILAFFATFVIGGLTGVMVAVVPFDWQVHDTHFIVAHLHYVLVGGF
VFPMLAALYYWMPHVTGRKRFFRVGDVAFWLVTVGFHATFLAVHWVGLLGQRRRTETYEPGQGWEVINLISSIGGFVMAI
GFALVILDVAMNALVAVRGSRNPWRAGTLEWAMPTPAPAYNFASLPEVSGRDPLHADPDLAVKIARGAFYLGEPRNGRRE
TLMVNVATGRPASLVVYPGNSALPFQLALVTGLFFLGMLLKTYWLVPLALVGVAALAIRWVWTNAPGRDEGPQPVGLGLS
LPRDVAQSPGWWGSLFLLLANGTLFGSLMFGYAFLWTVAPNWPPPAWLAPSGLQGALLLAGAASAPLLVRLADRTLRRGG
SPQAGLAGAALALGALAAAAGMLCLALPAPQRHAYDATVWVIAGYTGFHAGLALLMTLVVMAMQARGRLSAARISPLRIL
RLWTDWAAFAGLVGVAAALLPGLVA

Sequences:

>Translated_825_residues
MNALRRHRLLTRIWASEPGWRGWFTTVNHTDLGRMFLGASVVFFLIGGILAMLIRAQLASPRSAFVGAETYAQLFTMHGT
IMMFLFAIPMFEGLTIYLLPKMLGSRDLAYPRLSAYGFWCYVLGGSMLIVALLAGIAPDSGWFMYPPLASTLGSPGINSD
FWLLGITFVEISAIAAAVEIVVTVLRFRAPGMSLDRMPIYGWYALVTATMILTGFPPLILGSILLELERAFGLPFFQVAE
GGDSLLWQHLFWLFGHPEVYIIFLPAAGAISTILPVMARTELIGYRWVVAAAISLAVLSFGLWVHHMFTTGIPHMGLALF
SAASTLVAVPTAVQLFAWIGTLWRGTPEMRLPMMWILAFFATFVIGGLTGVMVAVVPFDWQVHDTHFIVAHLHYVLVGGF
VFPMLAALYYWMPHVTGRKRFFRVGDVAFWLVTVGFHATFLAVHWVGLLGQRRRTETYEPGQGWEVINLISSIGGFVMAI
GFALVILDVAMNALVAVRGSRNPWRAGTLEWAMPTPAPAYNFASLPEVSGRDPLHADPDLAVKIARGAFYLGEPRNGRRE
TLMVNVATGRPASLVVYPGNSALPFQLALVTGLFFLGMLLKTYWLVPLALVGVAALAIRWVWTNAPGRDEGPQPVGLGLS
LPRDVAQSPGWWGSLFLLLANGTLFGSLMFGYAFLWTVAPNWPPPAWLAPSGLQGALLLAGAASAPLLVRLADRTLRRGG
SPQAGLAGAALALGALAAAAGMLCLALPAPQRHAYDATVWVIAGYTGFHAGLALLMTLVVMAMQARGRLSAARISPLRIL
RLWTDWAAFAGLVGVAAALLPGLVA
>Mature_825_residues
MNALRRHRLLTRIWASEPGWRGWFTTVNHTDLGRMFLGASVVFFLIGGILAMLIRAQLASPRSAFVGAETYAQLFTMHGT
IMMFLFAIPMFEGLTIYLLPKMLGSRDLAYPRLSAYGFWCYVLGGSMLIVALLAGIAPDSGWFMYPPLASTLGSPGINSD
FWLLGITFVEISAIAAAVEIVVTVLRFRAPGMSLDRMPIYGWYALVTATMILTGFPPLILGSILLELERAFGLPFFQVAE
GGDSLLWQHLFWLFGHPEVYIIFLPAAGAISTILPVMARTELIGYRWVVAAAISLAVLSFGLWVHHMFTTGIPHMGLALF
SAASTLVAVPTAVQLFAWIGTLWRGTPEMRLPMMWILAFFATFVIGGLTGVMVAVVPFDWQVHDTHFIVAHLHYVLVGGF
VFPMLAALYYWMPHVTGRKRFFRVGDVAFWLVTVGFHATFLAVHWVGLLGQRRRTETYEPGQGWEVINLISSIGGFVMAI
GFALVILDVAMNALVAVRGSRNPWRAGTLEWAMPTPAPAYNFASLPEVSGRDPLHADPDLAVKIARGAFYLGEPRNGRRE
TLMVNVATGRPASLVVYPGNSALPFQLALVTGLFFLGMLLKTYWLVPLALVGVAALAIRWVWTNAPGRDEGPQPVGLGLS
LPRDVAQSPGWWGSLFLLLANGTLFGSLMFGYAFLWTVAPNWPPPAWLAPSGLQGALLLAGAASAPLLVRLADRTLRRGG
SPQAGLAGAALALGALAAAAGMLCLALPAPQRHAYDATVWVIAGYTGFHAGLALLMTLVVMAMQARGRLSAARISPLRIL
RLWTDWAAFAGLVGVAAALLPGLVA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=506, Percent_Identity=32.8063241106719, Blast_Score=275, Evalue=2e-73,
Organism=Escherichia coli, GI1786634, Length=613, Percent_Identity=33.278955954323, Blast_Score=341, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6226519, Length=532, Percent_Identity=30.6390977443609, Blast_Score=295, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=32.4074074074074, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6226523, Length=244, Percent_Identity=31.1475409836066, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 89424; Mature: 89424

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALRRHRLLTRIWASEPGWRGWFTTVNHTDLGRMFLGASVVFFLIGGILAMLIRAQLAS
CCHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRSAFVGAETYAQLFTMHGTIMMFLFAIPMFEGLTIYLLPKMLGSRDLAYPRLSAYGFWC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHCCCCCCCCCHHHHHHHH
YVLGGSMLIVALLAGIAPDSGWFMYPPLASTLGSPGINSDFWLLGITFVEISAIAAAVEI
HHHHHHHHHHHHHHHCCCCCCCEECCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VVTVLRFRAPGMSLDRMPIYGWYALVTATMILTGFPPLILGSILLELERAFGLPFFQVAE
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEECC
GGDSLLWQHLFWLFGHPEVYIIFLPAAGAISTILPVMARTELIGYRWVVAAAISLAVLSF
CCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLWVHHMFTTGIPHMGLALFSAASTLVAVPTAVQLFAWIGTLWRGTPEMRLPMMWILAFF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
ATFVIGGLTGVMVAVVPFDWQVHDTHFIVAHLHYVLVGGFVFPMLAALYYWMPHVTGRKR
HHHHHHHHHHHHHHEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
FFRVGDVAFWLVTVGFHATFLAVHWVGLLGQRRRTETYEPGQGWEVINLISSIGGFVMAI
HEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GFALVILDVAMNALVAVRGSRNPWRAGTLEWAMPTPAPAYNFASLPEVSGRDPLHADPDL
HHHHHHHHHHHHHHHEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AVKIARGAFYLGEPRNGRRETLMVNVATGRPASLVVYPGNSALPFQLALVTGLFFLGMLL
EEEEECCEEEECCCCCCCCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
KTYWLVPLALVGVAALAIRWVWTNAPGRDEGPQPVGLGLSLPRDVAQSPGWWGSLFLLLA
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHH
NGTLFGSLMFGYAFLWTVAPNWPPPAWLAPSGLQGALLLAGAASAPLLVRLADRTLRRGG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCC
SPQAGLAGAALALGALAAAAGMLCLALPAPQRHAYDATVWVIAGYTGFHAGLALLMTLVV
CCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHH
MAMQARGRLSAARISPLRILRLWTDWAAFAGLVGVAAALLPGLVA
HHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNALRRHRLLTRIWASEPGWRGWFTTVNHTDLGRMFLGASVVFFLIGGILAMLIRAQLAS
CCHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRSAFVGAETYAQLFTMHGTIMMFLFAIPMFEGLTIYLLPKMLGSRDLAYPRLSAYGFWC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHCCCCCCCCCHHHHHHHH
YVLGGSMLIVALLAGIAPDSGWFMYPPLASTLGSPGINSDFWLLGITFVEISAIAAAVEI
HHHHHHHHHHHHHHHCCCCCCCEECCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VVTVLRFRAPGMSLDRMPIYGWYALVTATMILTGFPPLILGSILLELERAFGLPFFQVAE
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEECC
GGDSLLWQHLFWLFGHPEVYIIFLPAAGAISTILPVMARTELIGYRWVVAAAISLAVLSF
CCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLWVHHMFTTGIPHMGLALFSAASTLVAVPTAVQLFAWIGTLWRGTPEMRLPMMWILAFF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
ATFVIGGLTGVMVAVVPFDWQVHDTHFIVAHLHYVLVGGFVFPMLAALYYWMPHVTGRKR
HHHHHHHHHHHHHHEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
FFRVGDVAFWLVTVGFHATFLAVHWVGLLGQRRRTETYEPGQGWEVINLISSIGGFVMAI
HEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GFALVILDVAMNALVAVRGSRNPWRAGTLEWAMPTPAPAYNFASLPEVSGRDPLHADPDL
HHHHHHHHHHHHHHHEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AVKIARGAFYLGEPRNGRRETLMVNVATGRPASLVVYPGNSALPFQLALVTGLFFLGMLL
EEEEECCEEEECCCCCCCCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
KTYWLVPLALVGVAALAIRWVWTNAPGRDEGPQPVGLGLSLPRDVAQSPGWWGSLFLLLA
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHH
NGTLFGSLMFGYAFLWTVAPNWPPPAWLAPSGLQGALLLAGAASAPLLVRLADRTLRRGG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCC
SPQAGLAGAALALGALAAAAGMLCLALPAPQRHAYDATVWVIAGYTGFHAGLALLMTLVV
CCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHH
MAMQARGRLSAARISPLRILRLWTDWAAFAGLVGVAAALLPGLVA
HHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377 [H]