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The map label for this gene is glpR [H]

Identifier: 77465079

GI number: 77465079

Start: 104527

End: 105309

Strand: Direct

Name: glpR [H]

Synonym: RSP_3064

Alternate gene names: 77465079

Gene position: 104527-105309 (Clockwise)

Preceding gene: 77465078

Following gene: 77465080

Centisome position: 11.08

GC content: 73.44

Gene sequence:

>783_bases
ATGCACGTTTCCCCCGATCTTCCCCGCGCCCGGCGCACCCTCATCGCCGAGCGCCTGCGCGCGGGCCAGCCCGTCGTGGC
CGCCGCGCTGGCCGAGGAATTCGGCGTCTCCGAGGATTCGATCCGCCGCGATCTCCGCTCCCTCGCACAGGAGGGGCTCT
GCCAGCGCGTCTACGGCGGCGCCCTGCCGCTCTCGCCGGCCTCGACCCCCATCGGGGCAAGGCTGGGCGAGGAGGCCGCG
CGCAAGCACGCCCTGGCCCGCTGCGCGGTGGATCTCATCCGGCCGGACCAGACCCTGTTCCTCGATGCGGGCAGCACGCT
CGTGCCGCTGGCCGGGCTGCTGCCCGAAGGGCAGGGGCTGCGCGTCGTCACCAATTCCATCCCGGCCGCCGCCGCCCTGA
TCGGGCGCAGCGGCATCGCGCTGGTCCTGATCGGGGGCGGCGTCACCATGAGCGTCGGCGGAGCCGTCGATGCGCAGGCT
CTGTCCGAGCTCGCACGCCTGCGGATCGACCTCTGCTTCCTCGGCGCCTGCGCCCTGTCTCCCGAAGAGGGGCTCGCGGG
CTTCGAGATGGACGATGTCGCCTTCAAGCGCCAGCTCCTGCGGCAGAGCCGGACGAGCGTGCTGATGATGACGAACGGCA
AGCTCGGCACGCAGGCTCCCTTCGCCATCGCCCGCGCGGACGAGATCGGCCACTACATCCTCGAGGCCGACGCGCCCGCA
GAGATGGAGCTGCGGCTCCGCCGGACCGGCGCCACCGTGCTCCGCGCGGCCCCGCCCGCCTGA

Upstream 100 bases:

>100_bases
CGGCGAAAGTCTCCCGACGGCTCCTTCCGTTGCGGCGGACTTGTGCCGAGACCACCGGGTTTGTCTGGCGCTGCACAGTC
TCGCATGATATTGCACGTTC

Downstream 100 bases:

>100_bases
GAAGGCCCGATCTCCCTCGGCCTGCCTCTCCTTCAGCCCGATCTCTCTCCGCTCGTCTCCCTCGGCCCGATCTCCCACAG
ACCGTCCATCCTCAGCCCGA

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MHVSPDLPRARRTLIAERLRAGQPVVAAALAEEFGVSEDSIRRDLRSLAQEGLCQRVYGGALPLSPASTPIGARLGEEAA
RKHALARCAVDLIRPDQTLFLDAGSTLVPLAGLLPEGQGLRVVTNSIPAAAALIGRSGIALVLIGGGVTMSVGGAVDAQA
LSELARLRIDLCFLGACALSPEEGLAGFEMDDVAFKRQLLRQSRTSVLMMTNGKLGTQAPFAIARADEIGHYILEADAPA
EMELRLRRTGATVLRAAPPA

Sequences:

>Translated_260_residues
MHVSPDLPRARRTLIAERLRAGQPVVAAALAEEFGVSEDSIRRDLRSLAQEGLCQRVYGGALPLSPASTPIGARLGEEAA
RKHALARCAVDLIRPDQTLFLDAGSTLVPLAGLLPEGQGLRVVTNSIPAAAALIGRSGIALVLIGGGVTMSVGGAVDAQA
LSELARLRIDLCFLGACALSPEEGLAGFEMDDVAFKRQLLRQSRTSVLMMTNGKLGTQAPFAIARADEIGHYILEADAPA
EMELRLRRTGATVLRAAPPA
>Mature_260_residues
MHVSPDLPRARRTLIAERLRAGQPVVAAALAEEFGVSEDSIRRDLRSLAQEGLCQRVYGGALPLSPASTPIGARLGEEAA
RKHALARCAVDLIRPDQTLFLDAGSTLVPLAGLLPEGQGLRVVTNSIPAAAALIGRSGIALVLIGGGVTMSVGGAVDAQA
LSELARLRIDLCFLGACALSPEEGLAGFEMDDVAFKRQLLRQSRTSVLMMTNGKLGTQAPFAIARADEIGHYILEADAPA
EMELRLRRTGATVLRAAPPA

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=210, Percent_Identity=31.9047619047619, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789519, Length=248, Percent_Identity=28.2258064516129, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789170, Length=228, Percent_Identity=29.8245614035088, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI226510968, Length=217, Percent_Identity=31.3364055299539, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789059, Length=231, Percent_Identity=25.5411255411255, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788069, Length=234, Percent_Identity=26.4957264957265, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87082344, Length=226, Percent_Identity=24.7787610619469, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790635, Length=248, Percent_Identity=25.4032258064516, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790753, Length=230, Percent_Identity=25.2173913043478, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787540, Length=243, Percent_Identity=23.0452674897119, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27287; Mature: 27287

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVSPDLPRARRTLIAERLRAGQPVVAAALAEEFGVSEDSIRRDLRSLAQEGLCQRVYGG
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
ALPLSPASTPIGARLGEEAARKHALARCAVDLIRPDQTLFLDAGSTLVPLAGLLPEGQGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCC
RVVTNSIPAAAALIGRSGIALVLIGGGVTMSVGGAVDAQALSELARLRIDLCFLGACALS
EEEECCCCHHHHHHCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
PEEGLAGFEMDDVAFKRQLLRQSRTSVLMMTNGKLGTQAPFAIARADEIGHYILEADAPA
CCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHCCEEEECCCCC
EMELRLRRTGATVLRAAPPA
HHHHEEECCCCEEEECCCCC
>Mature Secondary Structure
MHVSPDLPRARRTLIAERLRAGQPVVAAALAEEFGVSEDSIRRDLRSLAQEGLCQRVYGG
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
ALPLSPASTPIGARLGEEAARKHALARCAVDLIRPDQTLFLDAGSTLVPLAGLLPEGQGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCC
RVVTNSIPAAAALIGRSGIALVLIGGGVTMSVGGAVDAQALSELARLRIDLCFLGACALS
EEEECCCCHHHHHHCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
PEEGLAGFEMDDVAFKRQLLRQSRTSVLMMTNGKLGTQAPFAIARADEIGHYILEADAPA
CCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHCCEEEECCCCC
EMELRLRRTGATVLRAAPPA
HHHHEEECCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]