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The map label for this gene is cox15 [H]

Identifier: 77465013

GI number: 77465013

Start: 25912

End: 27087

Strand: Direct

Name: cox15 [H]

Synonym: RSP_3831

Alternate gene names: 77465013

Gene position: 25912-27087 (Clockwise)

Preceding gene: 77465012

Following gene: 77465014

Centisome position: 2.75

GC content: 69.39

Gene sequence:

>1176_bases
ATGGCAGTGAAAAAGCGCAGCATCTTCGAGGAAGTGGGGCAGGGGGCGAAGGCGCCGGTCCCGCAGGGCGGCAGCATCGA
CCGCGGCCATGGCGGCGCCCGGCGCGGCATCCGGCTGTGGCTGATGGCCCTGTTCCTCCTCGTGATGGCGATGATCGTGG
TGGGCGGCCTCACGCGGCTGACCGACTCCGGCCTCTCCATCACCGAATGGCGCCCCGTCACCGGCGCGGTGCCGCCCCTG
AACGAGACCCAGTGGGCGGCCGAGTTCGACAAATACCGCGACAGCCCGCAATACCGGCTGATGAACGCCGGCATGACCCT
GGCCGAGTTCCAGCGCATCTACTGGTGGGAATGGGGCCATCGCCAGCTCGGCCGCGTGATCGGCCTCGTCTGGGCGGTGG
GCTTCCTGGGCTTCCTCGCGGCGCGCAGGATCCCGCGCGGCTGGTGGCCGCGGCTTCTGGCGCTGGGGGCTCTGGGCGGT
CTTCAGGGCGGGATCGGCTGGTGGATGGTGGCCTCGGGCCTCGAAGGCGACAAGGTCACCGTCGAGAGCACGCGGCTCGC
CACGCACCTCGGTCTCGCCTTCATCATTCTCGGTCTGATCGCCTGGCAGGCGCTCCTGCTCGGGCGCAGCGAATCCGATC
TCCTGCAGGCCCGGCGCCAGAAGGATGGGCGGCTCGTGACCCTCACCACCGTGCTGATCGGCGTGGCCTTCCTTCAGATC
GTGCTGGGCGCGCTGGTCGCGGGCATCGACGCGGGCCGCGGCTTTCCCACCTGGCCCGACATGAACGGCACCTTCCTGCC
CGCCGAGATGTTCTATGTGCCGGGCGTCGAGACGGACTGGAGGAACCCCGCCTGGTGGCTGGGTCTCCTGCAGAACCCGG
GCTTCGTCCAGTTCCTGCACCGGATGGCCGGCTATACGCTGGCGGCGCTCGGCCTGATCTTCTGGATCTTCGGCCGCCGC
TCGCGGCACCGGGCGACCCGCGGCGCCTTCGATCTTCTCGCCATGGCGCTTCTGGCGCAGATCCTGCTCGGCGTGGGCAC
CGTGCTCTCGGCCGCGGAATGGCAGGTCGCCATCGCCCATCAGGTCGGCGCGGTCGTGATCTGGGTGCTGATCCTCCATG
CCCGTCACCTTGCGCTGTATCCCCGCGTGGGCTCGATCCGGAAAGGAACGCTATGA

Upstream 100 bases:

>100_bases
GCCGGCCCAAGCCTAGATCCGCGTCCCTGCGCCACCCCCCGCGAGCCCTTGAAGCGGGCAGGCGGGGGGCCTAGTCTCCC
CGGCGGAACGGGAGAGCCGG

Downstream 100 bases:

>100_bases
GCGCCGACGTCGCCTTCACCGAACTGATGGACTATCAGCGCCAGACCGAGGCGCTGGCACAGGTCATGGGCCGGCTCTCC
TGGGACCAGGAGACGGTGAT

Product: putative cytochrome oxidase assembly factor

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MAVKKRSIFEEVGQGAKAPVPQGGSIDRGHGGARRGIRLWLMALFLLVMAMIVVGGLTRLTDSGLSITEWRPVTGAVPPL
NETQWAAEFDKYRDSPQYRLMNAGMTLAEFQRIYWWEWGHRQLGRVIGLVWAVGFLGFLAARRIPRGWWPRLLALGALGG
LQGGIGWWMVASGLEGDKVTVESTRLATHLGLAFIILGLIAWQALLLGRSESDLLQARRQKDGRLVTLTTVLIGVAFLQI
VLGALVAGIDAGRGFPTWPDMNGTFLPAEMFYVPGVETDWRNPAWWLGLLQNPGFVQFLHRMAGYTLAALGLIFWIFGRR
SRHRATRGAFDLLAMALLAQILLGVGTVLSAAEWQVAIAHQVGAVVIWVLILHARHLALYPRVGSIRKGTL

Sequences:

>Translated_391_residues
MAVKKRSIFEEVGQGAKAPVPQGGSIDRGHGGARRGIRLWLMALFLLVMAMIVVGGLTRLTDSGLSITEWRPVTGAVPPL
NETQWAAEFDKYRDSPQYRLMNAGMTLAEFQRIYWWEWGHRQLGRVIGLVWAVGFLGFLAARRIPRGWWPRLLALGALGG
LQGGIGWWMVASGLEGDKVTVESTRLATHLGLAFIILGLIAWQALLLGRSESDLLQARRQKDGRLVTLTTVLIGVAFLQI
VLGALVAGIDAGRGFPTWPDMNGTFLPAEMFYVPGVETDWRNPAWWLGLLQNPGFVQFLHRMAGYTLAALGLIFWIFGRR
SRHRATRGAFDLLAMALLAQILLGVGTVLSAAEWQVAIAHQVGAVVIWVLILHARHLALYPRVGSIRKGTL
>Mature_390_residues
AVKKRSIFEEVGQGAKAPVPQGGSIDRGHGGARRGIRLWLMALFLLVMAMIVVGGLTRLTDSGLSITEWRPVTGAVPPLN
ETQWAAEFDKYRDSPQYRLMNAGMTLAEFQRIYWWEWGHRQLGRVIGLVWAVGFLGFLAARRIPRGWWPRLLALGALGGL
QGGIGWWMVASGLEGDKVTVESTRLATHLGLAFIILGLIAWQALLLGRSESDLLQARRQKDGRLVTLTTVLIGVAFLQIV
LGALVAGIDAGRGFPTWPDMNGTFLPAEMFYVPGVETDWRNPAWWLGLLQNPGFVQFLHRMAGYTLAALGLIFWIFGRRS
RHRATRGAFDLLAMALLAQILLGVGTVLSAAEWQVAIAHQVGAVVIWVLILHARHLALYPRVGSIRKGTL

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group [H]

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921985, Length=357, Percent_Identity=33.3333333333333, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI17921987, Length=326, Percent_Identity=33.7423312883436, Blast_Score=159, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17536069, Length=362, Percent_Identity=33.7016574585635, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6320989, Length=355, Percent_Identity=35.4929577464789, Blast_Score=190, Evalue=3e-49,
Organism=Drosophila melanogaster, GI19922860, Length=383, Percent_Identity=32.3759791122715, Blast_Score=165, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003780 [H]

Pfam domain/function: PF02628 COX15-CtaA [H]

EC number: NA

Molecular weight: Translated: 43079; Mature: 42948

Theoretical pI: Translated: 11.44; Mature: 11.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AVKKRSIFEEVGQGAKAPVPQGGSIDRGHGGARRGIRLWLMALFLLVMAMIVVGGLTRL
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TDSGLSITEWRPVTGAVPPLNETQWAAEFDKYRDSPQYRLMNAGMTLAEFQRIYWWEWGH
HCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHH
RQLGRVIGLVWAVGFLGFLAARRIPRGWWPRLLALGALGGLQGGIGWWMVASGLEGDKVT
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEE
VESTRLATHLGLAFIILGLIAWQALLLGRSESDLLQARRQKDGRLVTLTTVLIGVAFLQI
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
VLGALVAGIDAGRGFPTWPDMNGTFLPAEMFYVPGVETDWRNPAWWLGLLQNPGFVQFLH
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCHHHHHHHCCCCHHHHHH
RMAGYTLAALGLIFWIFGRRSRHRATRGAFDLLAMALLAQILLGVGTVLSAAEWQVAIAH
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVGAVVIWVLILHARHLALYPRVGSIRKGTL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA