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The map label for this gene is yhdP [H]

Identifier: 77461829

GI number: 77461829

Start: 6280114

End: 6281454

Strand: Direct

Name: yhdP [H]

Synonym: Pfl01_5608

Alternate gene names: 77461829

Gene position: 6280114-6281454 (Clockwise)

Preceding gene: 77461828

Following gene: 77461838

Centisome position: 97.54

GC content: 61.3

Gene sequence:

>1341_bases
ATGGACCCTTCCCCTGGCTTGTCCCTCGCAACCATATTCGCCGATTTCGGCATGATTCTTTTCGCTCTGATCCTGGTTCT
GCTCAACGGCTTCTTCGTTGCGGCGGAGTTCGCCATGGTCAAACTGCGCTCGACCCGGGTCGAAGCCATCGCTGAACAGC
ACGGCTGGCGCGGGCACATCCTGCGCACCGTACACAGTCAGCTCGATGCTTACCTCTCGGCGTGCCAGTTCGGTATCACC
CTCGCCTCCCTCGGCCTGGGCTGGGTCGGCGAGCCGGCGTTCGCGCACATTCTCGAACCGCTACTGAGCGCGGTCGGCGT
GCAGTCGGCCGAAGTCGTCAAAGGCATTTCGTTCTTCACCGCGTTCTTCATCATTTCCTACCTGCACATCGTGGTCGGCG
AACTCGCACCCAAATCCTGGGCGATCCGCAAACCCGAGCTGCTGTCGCTGTGGACGGCGGTGCCGCTGTACCTGTTCTAC
TGGGCCATGTACCCGGCGATCTACCTGCTCAATGCCAGCGCCAACACCATCCTGCGCATTGCGGGTCAAGGTGAACCCGG
GCCGCATCACGAGCACCATTACAGCCGCGAAGAACTGAAACTGATCCTGCACTCCAGCCGTGGCCAGGACCCGAGCGACC
AGGGCATGCGCGTGCTGGCCTCGGCGGTGGAAATGGGCGAACTGGAAGTGGTCGACTGGGCCAACTCCCGGGAAGACCTG
ATCACCCTCGAGTTCAACGCCCCGCTGAAAGAAATCCTGGCGATGTTCCGCCGCCACAAATTTAGCCGTTATCCGGTGTA
CGACAGCGAGCGCAAGGAATTCGTCGGCCTGCTGCACATCAAGGATCTGCTGCTGGAACTGGCAGCGCTGGATCACATTC
CCGAGTCGTTCAACCTCGCCGAGCTGACCCGCCCGCTGGAGCGCGTTTCCCGGCACATGCCGCTGTCGCAGCTGCTGGAG
CAGTTCCGCAAGGGCGGCTCGCACTTCGCTGTGGTCGAAGAAGCCGACGGCAACATCATCGGCTACCTGACCATGGAAGA
CGTGCTGGAAGTGCTGGTCGGCGATATCCAGGACGAACACCGCAAGGCCGAGCGCGGCATCCTCGCCTATCAGCCGGGCA
AGTTGCTGGTGCGGGGCGATACGCCGCTGTTCAAGGTCGAGCGCCTGCTGGGGATCGACCTGGACCACATCGAAGCCGAA
ACCCTCGCCGGGCTGATCTACGAAACCCTGAAACGGGTGCCGGAAGAGGAAGAAGTGCTGGAAGTCGAAGGCCTGCGGAT
CATCATCAAGAAGATGAAAGGTCCAAAGATCATTCTGGCCAAGGTGCTGATGCTCGACTGA

Upstream 100 bases:

>100_bases
GCAATCGCCAGGTCAGCCGCTACATTGGCTGACTTGCGCCTGCCTTTCAGGTGCGGATTTTTCTTTCTTTCGAATCACAC
GGAACCCGCAAAACTCCATC

Downstream 100 bases:

>100_bases
CGGGGTTTACTGCTTGCCCAACGCAAAGTTGGGCAACGCCCCCAGCGGCCGGTTGAACTGATACGGAATCGACACCAGCC
CCATCCCGGTATTGCGCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MDPSPGLSLATIFADFGMILFALILVLLNGFFVAAEFAMVKLRSTRVEAIAEQHGWRGHILRTVHSQLDAYLSACQFGIT
LASLGLGWVGEPAFAHILEPLLSAVGVQSAEVVKGISFFTAFFIISYLHIVVGELAPKSWAIRKPELLSLWTAVPLYLFY
WAMYPAIYLLNASANTILRIAGQGEPGPHHEHHYSREELKLILHSSRGQDPSDQGMRVLASAVEMGELEVVDWANSREDL
ITLEFNAPLKEILAMFRRHKFSRYPVYDSERKEFVGLLHIKDLLLELAALDHIPESFNLAELTRPLERVSRHMPLSQLLE
QFRKGGSHFAVVEEADGNIIGYLTMEDVLEVLVGDIQDEHRKAERGILAYQPGKLLVRGDTPLFKVERLLGIDLDHIEAE
TLAGLIYETLKRVPEEEEVLEVEGLRIIIKKMKGPKIILAKVLMLD

Sequences:

>Translated_446_residues
MDPSPGLSLATIFADFGMILFALILVLLNGFFVAAEFAMVKLRSTRVEAIAEQHGWRGHILRTVHSQLDAYLSACQFGIT
LASLGLGWVGEPAFAHILEPLLSAVGVQSAEVVKGISFFTAFFIISYLHIVVGELAPKSWAIRKPELLSLWTAVPLYLFY
WAMYPAIYLLNASANTILRIAGQGEPGPHHEHHYSREELKLILHSSRGQDPSDQGMRVLASAVEMGELEVVDWANSREDL
ITLEFNAPLKEILAMFRRHKFSRYPVYDSERKEFVGLLHIKDLLLELAALDHIPESFNLAELTRPLERVSRHMPLSQLLE
QFRKGGSHFAVVEEADGNIIGYLTMEDVLEVLVGDIQDEHRKAERGILAYQPGKLLVRGDTPLFKVERLLGIDLDHIEAE
TLAGLIYETLKRVPEEEEVLEVEGLRIIIKKMKGPKIILAKVLMLD
>Mature_446_residues
MDPSPGLSLATIFADFGMILFALILVLLNGFFVAAEFAMVKLRSTRVEAIAEQHGWRGHILRTVHSQLDAYLSACQFGIT
LASLGLGWVGEPAFAHILEPLLSAVGVQSAEVVKGISFFTAFFIISYLHIVVGELAPKSWAIRKPELLSLWTAVPLYLFY
WAMYPAIYLLNASANTILRIAGQGEPGPHHEHHYSREELKLILHSSRGQDPSDQGMRVLASAVEMGELEVVDWANSREDL
ITLEFNAPLKEILAMFRRHKFSRYPVYDSERKEFVGLLHIKDLLLELAALDHIPESFNLAELTRPLERVSRHMPLSQLLE
QFRKGGSHFAVVEEADGNIIGYLTMEDVLEVLVGDIQDEHRKAERGILAYQPGKLLVRGDTPLFKVERLLGIDLDHIEAE
TLAGLIYETLKRVPEEEEVLEVEGLRIIIKKMKGPKIILAKVLMLD

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=379, Percent_Identity=35.8839050131926, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI40068053, Length=260, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI40068055, Length=260, Percent_Identity=27.6923076923077, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1790664, Length=421, Percent_Identity=22.3277909738717, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI145693175, Length=390, Percent_Identity=22.5641025641026, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082033, Length=264, Percent_Identity=28.030303030303, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786879, Length=259, Percent_Identity=25.0965250965251, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50070; Mature: 50070

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPSPGLSLATIFADFGMILFALILVLLNGFFVAAEFAMVKLRSTRVEAIAEQHGWRGHI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LRTVHSQLDAYLSACQFGITLASLGLGWVGEPAFAHILEPLLSAVGVQSAEVVKGISFFT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AFFIISYLHIVVGELAPKSWAIRKPELLSLWTAVPLYLFYWAMYPAIYLLNASANTILRI
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEE
AGQGEPGPHHEHHYSREELKLILHSSRGQDPSDQGMRVLASAVEMGELEVVDWANSREDL
ECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCE
ITLEFNAPLKEILAMFRRHKFSRYPVYDSERKEFVGLLHIKDLLLELAALDHIPESFNLA
EEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
ELTRPLERVSRHMPLSQLLEQFRKGGSHFAVVEEADGNIIGYLTMEDVLEVLVGDIQDEH
HHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHH
RKAERGILAYQPGKLLVRGDTPLFKVERLLGIDLDHIEAETLAGLIYETLKRVPEEEEVL
HHHHCCEEEECCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
EVEGLRIIIKKMKGPKIILAKVLMLD
HHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MDPSPGLSLATIFADFGMILFALILVLLNGFFVAAEFAMVKLRSTRVEAIAEQHGWRGHI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LRTVHSQLDAYLSACQFGITLASLGLGWVGEPAFAHILEPLLSAVGVQSAEVVKGISFFT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AFFIISYLHIVVGELAPKSWAIRKPELLSLWTAVPLYLFYWAMYPAIYLLNASANTILRI
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEE
AGQGEPGPHHEHHYSREELKLILHSSRGQDPSDQGMRVLASAVEMGELEVVDWANSREDL
ECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCE
ITLEFNAPLKEILAMFRRHKFSRYPVYDSERKEFVGLLHIKDLLLELAALDHIPESFNLA
EEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
ELTRPLERVSRHMPLSQLLEQFRKGGSHFAVVEEADGNIIGYLTMEDVLEVLVGDIQDEH
HHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHH
RKAERGILAYQPGKLLVRGDTPLFKVERLLGIDLDHIEAETLAGLIYETLKRVPEEEEVL
HHHHCCEEEECCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
EVEGLRIIIKKMKGPKIILAKVLMLD
HHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]