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The map label for this gene is glpT [H]

Identifier: 77461672

GI number: 77461672

Start: 6116332

End: 6117681

Strand: Direct

Name: glpT [H]

Synonym: Pfl01_5451

Alternate gene names: 77461672

Gene position: 6116332-6117681 (Clockwise)

Preceding gene: 255961283

Following gene: 77461680

Centisome position: 95.0

GC content: 61.26

Gene sequence:

>1350_bases
ATGTTTGCTTTCTTTCGTCCTGCCGCACATCAGGCTCCATTGCCTGAAGAAAAAATCGACAGCACCTACCGACGCCTGCG
TTGGCAGATCTTCGCCGGCATCTTCTTTGGTTACGCGGGTTACTACCTGCTGCGCAAGAACTTCTCGCTGGCCATGCCGT
ACCTGATCGACGAAGGCTACAGCCGTGGCGATCTGGGCCTGGCAATGTCGGCCATCGCCATCGCCTACGGTCTGTCCAAG
TTCCTCATGGGCCTGGTTTCCGACCGCTCCAACCCGCGTTACTTCCTGCCGTTCGGCCTGCTGGTATCGGCCGGGGTGAT
GTTCATTTTCGGTTTCGCGCCTTGGGCAACCTCCAGCGTGACCATGATGTTCATCCTGCTGTTCATCAACGGTTGGGCCC
AGGGCATGGGCTGGCCGCCGAGCGGACGCACGATGGTGCACTGGTGGTCGCAGAAGGAACGTGGCGGCGTGGTGTCGGTG
TGGAACGTGGCGCATAACGTCGGTGGCGGTCTGATCGGCCCGCTGTTCCTGATCGGCATGGGCCTGTTCAACGACTGGCA
CGCAGCGTTCTACGTCCCGGCCGCCGTGGCTCTGGCAGTAGCGGTGTTCGCTTTCGTGACCATGCGTGACACCCCGCAAT
CGGTCGGCCTGCCGCCGATCGAGAAGTACAAGAACGACTACCCGGAAGGCTACGACGCCAGCCACGAAGACGAATTCAGC
GCCAAGGAAATCTTCGTCAAATACGTGCTGCGCAACAAAATGCTCTGGTACATCGCCATGGCCAACGTCTTCGTCTACCT
GCTGCGTTACGGCGTGCTGGACTGGGCGCCGACCTACCTGAAAGAAGCCAAGGGTTTCACCGTGGATAAAACCTCGTGGG
CCTATTTCTTCTACGAATGGGCGGGGATTCCGGGCACGCTGCTGTGCGGCTGGATGTCGGACAAGATCTTCCGTGGCAAC
CGTGGCCTGACCGGCATGGTGTTCATGGCCCTGGTGACCGTCGCGACGCTGGTGTACTGGCTGAACCCGGCCGGCAACCC
GACCATCGACATGATCGCGCTGTTCTCAATCGGCTTCCTGATCTACGGCCCGGTGATGCTGATCGGCCTGCAAGCGCTGG
AACTGGCGCCGAAGAAAGCCGCCGGCACTGCCGCAGGCTTCACCGGTCTGTTCGGGTATCTGGGTGGTTCGGTCGCGGCC
AGTGCAGCGATGGGCTACACCGTGGACCATTTCGGCTGGGATGGTGGTTTCGTGCTGCTGGTGGGCGCTTGCCTGCTGTC
GATGGCCTTCCTGGCCCCGACCCTGTGGCACAAGCAAGTCGCCAGTCAGAGCCGTGAAGCGGTCGCCTGA

Upstream 100 bases:

>100_bases
ACATTTTCCACTGTTTTGCCGATGGTAAGCGGTGCTATTTTCGGTAACGAAACTGTAACATTCGCATCCGCAGTCAAAAC
AAGAAATCTGGAGCTCTTGA

Downstream 100 bases:

>100_bases
TCGGCCTTTGACTTACAGCGCTTGAGCCGCGCCTCCAGATTCCGGTCTGGCATGGCGTGGCTGCGCAGGGCGTGAGCGGT
CTGCTCGACATAATCGCGAG

Product: sn-glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MFAFFRPAAHQAPLPEEKIDSTYRRLRWQIFAGIFFGYAGYYLLRKNFSLAMPYLIDEGYSRGDLGLAMSAIAIAYGLSK
FLMGLVSDRSNPRYFLPFGLLVSAGVMFIFGFAPWATSSVTMMFILLFINGWAQGMGWPPSGRTMVHWWSQKERGGVVSV
WNVAHNVGGGLIGPLFLIGMGLFNDWHAAFYVPAAVALAVAVFAFVTMRDTPQSVGLPPIEKYKNDYPEGYDASHEDEFS
AKEIFVKYVLRNKMLWYIAMANVFVYLLRYGVLDWAPTYLKEAKGFTVDKTSWAYFFYEWAGIPGTLLCGWMSDKIFRGN
RGLTGMVFMALVTVATLVYWLNPAGNPTIDMIALFSIGFLIYGPVMLIGLQALELAPKKAAGTAAGFTGLFGYLGGSVAA
SAAMGYTVDHFGWDGGFVLLVGACLLSMAFLAPTLWHKQVASQSREAVA

Sequences:

>Translated_449_residues
MFAFFRPAAHQAPLPEEKIDSTYRRLRWQIFAGIFFGYAGYYLLRKNFSLAMPYLIDEGYSRGDLGLAMSAIAIAYGLSK
FLMGLVSDRSNPRYFLPFGLLVSAGVMFIFGFAPWATSSVTMMFILLFINGWAQGMGWPPSGRTMVHWWSQKERGGVVSV
WNVAHNVGGGLIGPLFLIGMGLFNDWHAAFYVPAAVALAVAVFAFVTMRDTPQSVGLPPIEKYKNDYPEGYDASHEDEFS
AKEIFVKYVLRNKMLWYIAMANVFVYLLRYGVLDWAPTYLKEAKGFTVDKTSWAYFFYEWAGIPGTLLCGWMSDKIFRGN
RGLTGMVFMALVTVATLVYWLNPAGNPTIDMIALFSIGFLIYGPVMLIGLQALELAPKKAAGTAAGFTGLFGYLGGSVAA
SAAMGYTVDHFGWDGGFVLLVGACLLSMAFLAPTLWHKQVASQSREAVA
>Mature_449_residues
MFAFFRPAAHQAPLPEEKIDSTYRRLRWQIFAGIFFGYAGYYLLRKNFSLAMPYLIDEGYSRGDLGLAMSAIAIAYGLSK
FLMGLVSDRSNPRYFLPFGLLVSAGVMFIFGFAPWATSSVTMMFILLFINGWAQGMGWPPSGRTMVHWWSQKERGGVVSV
WNVAHNVGGGLIGPLFLIGMGLFNDWHAAFYVPAAVALAVAVFAFVTMRDTPQSVGLPPIEKYKNDYPEGYDASHEDEFS
AKEIFVKYVLRNKMLWYIAMANVFVYLLRYGVLDWAPTYLKEAKGFTVDKTSWAYFFYEWAGIPGTLLCGWMSDKIFRGN
RGLTGMVFMALVTVATLVYWLNPAGNPTIDMIALFSIGFLIYGPVMLIGLQALELAPKKAAGTAAGFTGLFGYLGGSVAA
SAAMGYTVDHFGWDGGFVLLVGACLLSMAFLAPTLWHKQVASQSREAVA

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=419, Percent_Identity=27.9236276849642, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI4503847, Length=419, Percent_Identity=27.9236276849642, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI256219483, Length=419, Percent_Identity=27.9236276849642, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI256219543, Length=442, Percent_Identity=27.6018099547511, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI256219564, Length=338, Percent_Identity=25.1479289940828, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI223717983, Length=479, Percent_Identity=23.3820459290188, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI38093649, Length=479, Percent_Identity=23.3820459290188, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI46361976, Length=399, Percent_Identity=25.062656641604, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI49619231, Length=337, Percent_Identity=23.4421364985163, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI14150047, Length=259, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1788573, Length=431, Percent_Identity=73.0858468677494, Blast_Score=674, Evalue=0.0,
Organism=Escherichia coli, GI87082310, Length=446, Percent_Identity=37.6681614349776, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI2367259, Length=460, Percent_Identity=31.9565217391304, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1789515, Length=434, Percent_Identity=23.2718894009217, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082320, Length=421, Percent_Identity=23.7529691211401, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI2367379, Length=326, Percent_Identity=22.3926380368098, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789152, Length=382, Percent_Identity=21.4659685863874, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI133901854, Length=452, Percent_Identity=25.4424778761062, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI133901856, Length=452, Percent_Identity=25.4424778761062, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI133930953, Length=476, Percent_Identity=21.218487394958, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17542316, Length=462, Percent_Identity=22.7272727272727, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564204, Length=366, Percent_Identity=25.4098360655738, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564202, Length=435, Percent_Identity=24.367816091954, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24656861, Length=481, Percent_Identity=23.0769230769231, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24656866, Length=481, Percent_Identity=23.0769230769231, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45550478, Length=481, Percent_Identity=23.0769230769231, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49601; Mature: 49601

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3329281; 9205837; 9278503; 3141744; 12893936 [H]