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The map label for this gene is pqqL [C]

Identifier: 77461559

GI number: 77461559

Start: 5997841

End: 5999196

Strand: Direct

Name: pqqL [C]

Synonym: Pfl01_5338

Alternate gene names: 77461559

Gene position: 5997841-5999196 (Clockwise)

Preceding gene: 77461554

Following gene: 77461560

Centisome position: 93.16

GC content: 64.38

Gene sequence:

>1356_bases
ATGAATGCTCTAGCCCGCCGCGCCGCAGGCCTGCTGCTCAGCACAGTCTGCCTGCCCCTTTCGGCCCTGGCGGCCGACCC
GCAACCGACACACGAATTCACCCTCGACAACGGCCTGAAGGTCGTCGTGCGCGAAGACCATCGCGCGCCGGTGGTAGTGT
CGCAGGTCTGGTACAAGGTCGGCTCCAGCTACGAAACTCCGGGCCAGACCGGTCTGTCCCACGCCCTCGAGCACATGATG
TTCAAGGGCAGCGAGAAAGTCGGCCCCGGCGAAGCCTCGCTGATCCTGCGCGACCTCGGCGCCGAAGAGAACGCGTTCAC
CAGCGACGACTTCACCGCTTATTACCAGGTGCTGGCCCGCGACCGTCTGGGCGTGGCCTTCGAACTGGAAGCCGACCGCA
TGGCCAACCTGCGCCTGCCGGCCGACGAGTTCGCCAAGGAAATCGAAGTCATCAAGGAAGAGCGCCGTCTGCGCACCGAC
GACAAGCCGATGGCCAAGGCCTACGAGCGCTACAAGGCCATGGCCTACCCGGCCAGCGGTTACCACACGCCGACCATCGG
CTGGATGGCCGACCTTGAGCGGATGAAGGTCGAAGAGCTGCGCCACTGGTATCAGTCCTGGTACGTGCCGAACAACGCCA
CACTGGTGGTGGTCGGCGACGTGACCCCGGACGAGGTGAAGACCCTCGCCCAGCGCTACTTCGGGCCGATCCCGAAACGC
GACGTGCCGCCGGCGAAAAAGCCGCTGGAACTGGCCGAACCGGGTGAACGCCAGATCACCCTGCACGTGCAGACTCAACT
GCCGAGCCTGATGCTTGGTTTCAACGTCCCGAGCATCGCCACCGCCGAAGACAAACGTTCGGTCAACGCCTTGCGCCTGA
TTTCGGCGCTGCTGGACGGCGGCTACAGCGGTCGCATCCCGACCCAACTGGAGCGTGGCGAAGAACTGGTGTCCGGCGGT
TCGTCGAGCTACGACGCCTACACCCGCGGCGACAGCCTTTTCACCCTGTCGGCCACGCCGAACACCCAGAAGAAAAAGAC
CATGGCCCAGGCGGAAGCCGGCCTGTGGAAACTGCTGGAGCAGCTGAAAACCAGCGCACCGTCCGCCGAAGAACTGGAAC
GCGTGCGTGCGCAGGTCATCGCCGGTCTGGTCTTCGAGCGTGATTCGATCACCAGCCAGGCCACCGCCATCGGCCAGCTG
GAGACCGTCGGTCTGTCGTGGAAGCTGATGGACACCGAACTGGCCGACCTGGAAAGCGTCACCCCGCAAGACATCCAGAA
CGCCGCCAAGCTGTATTTCACCCGCGAACGTCTCAGCGTCGCCCACGTCCTGCCACTGGAGACGACTCATGAGTGA

Upstream 100 bases:

>100_bases
CCGGATAGGCGTGGTCGCCGGTAAAACGGATCAGTATCCTAGCACCCTCTCGCCCGCCGACGCTAAGACCAAGCGGGCAG
CCCAACAGGTTTAAAAACGA

Downstream 100 bases:

>100_bases
GCGCAAAACCCCACGCCTGCTGCTCGGCCTGATCGCCGTGGCCATCATCGGCTCCGCCGCGTTCTATCTGGTGCCGAGCG
ACAACACCAAGGCCAGCGAA

Product: peptidase M16-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MNALARRAAGLLLSTVCLPLSALAADPQPTHEFTLDNGLKVVVREDHRAPVVVSQVWYKVGSSYETPGQTGLSHALEHMM
FKGSEKVGPGEASLILRDLGAEENAFTSDDFTAYYQVLARDRLGVAFELEADRMANLRLPADEFAKEIEVIKEERRLRTD
DKPMAKAYERYKAMAYPASGYHTPTIGWMADLERMKVEELRHWYQSWYVPNNATLVVVGDVTPDEVKTLAQRYFGPIPKR
DVPPAKKPLELAEPGERQITLHVQTQLPSLMLGFNVPSIATAEDKRSVNALRLISALLDGGYSGRIPTQLERGEELVSGG
SSSYDAYTRGDSLFTLSATPNTQKKKTMAQAEAGLWKLLEQLKTSAPSAEELERVRAQVIAGLVFERDSITSQATAIGQL
ETVGLSWKLMDTELADLESVTPQDIQNAAKLYFTRERLSVAHVLPLETTHE

Sequences:

>Translated_451_residues
MNALARRAAGLLLSTVCLPLSALAADPQPTHEFTLDNGLKVVVREDHRAPVVVSQVWYKVGSSYETPGQTGLSHALEHMM
FKGSEKVGPGEASLILRDLGAEENAFTSDDFTAYYQVLARDRLGVAFELEADRMANLRLPADEFAKEIEVIKEERRLRTD
DKPMAKAYERYKAMAYPASGYHTPTIGWMADLERMKVEELRHWYQSWYVPNNATLVVVGDVTPDEVKTLAQRYFGPIPKR
DVPPAKKPLELAEPGERQITLHVQTQLPSLMLGFNVPSIATAEDKRSVNALRLISALLDGGYSGRIPTQLERGEELVSGG
SSSYDAYTRGDSLFTLSATPNTQKKKTMAQAEAGLWKLLEQLKTSAPSAEELERVRAQVIAGLVFERDSITSQATAIGQL
ETVGLSWKLMDTELADLESVTPQDIQNAAKLYFTRERLSVAHVLPLETTHE
>Mature_451_residues
MNALARRAAGLLLSTVCLPLSALAADPQPTHEFTLDNGLKVVVREDHRAPVVVSQVWYKVGSSYETPGQTGLSHALEHMM
FKGSEKVGPGEASLILRDLGAEENAFTSDDFTAYYQVLARDRLGVAFELEADRMANLRLPADEFAKEIEVIKEERRLRTD
DKPMAKAYERYKAMAYPASGYHTPTIGWMADLERMKVEELRHWYQSWYVPNNATLVVVGDVTPDEVKTLAQRYFGPIPKR
DVPPAKKPLELAEPGERQITLHVQTQLPSLMLGFNVPSIATAEDKRSVNALRLISALLDGGYSGRIPTQLERGEELVSGG
SSSYDAYTRGDSLFTLSATPNTQKKKTMAQAEAGLWKLLEQLKTSAPSAEELERVRAQVIAGLVFERDSITSQATAIGQL
ETVGLSWKLMDTELADLESVTPQDIQNAAKLYFTRERLSVAHVLPLETTHE

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=223, Percent_Identity=30.4932735426009, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI94538354, Length=222, Percent_Identity=28.8288288288288, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1787770, Length=387, Percent_Identity=26.3565891472868, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI2367164, Length=339, Percent_Identity=26.5486725663717, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17553678, Length=226, Percent_Identity=28.7610619469027, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71999683, Length=223, Percent_Identity=24.6636771300448, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323421, Length=348, Percent_Identity=22.7011494252874, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=401, Percent_Identity=22.6932668329177, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21357875, Length=218, Percent_Identity=28.8990825688073, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646943, Length=218, Percent_Identity=28.8990825688073, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49986; Mature: 49986

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALARRAAGLLLSTVCLPLSALAADPQPTHEFTLDNGLKVVVREDHRAPVVVSQVWYKV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEECCCCCCCHHHHHHHHH
GSSYETPGQTGLSHALEHMMFKGSEKVGPGEASLILRDLGAEENAFTSDDFTAYYQVLAR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
DRLGVAFELEADRMANLRLPADEFAKEIEVIKEERRLRTDDKPMAKAYERYKAMAYPASG
HCCCEEEEECHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
YHTPTIGWMADLERMKVEELRHWYQSWYVPNNATLVVVGDVTPDEVKTLAQRYFGPIPKR
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCC
DVPPAKKPLELAEPGERQITLHVQTQLPSLMLGFNVPSIATAEDKRSVNALRLISALLDG
CCCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
GYSGRIPTQLERGEELVSGGSSSYDAYTRGDSLFTLSATPNTQKKKTMAQAEAGLWKLLE
CCCCCCCHHHHHHHHHHCCCCCCCCCEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
QLKTSAPSAEELERVRAQVIAGLVFERDSITSQATAIGQLETVGLSWKLMDTELADLESV
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCEEEEECCHHHHHHCC
TPQDIQNAAKLYFTRERLSVAHVLPLETTHE
CHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure
MNALARRAAGLLLSTVCLPLSALAADPQPTHEFTLDNGLKVVVREDHRAPVVVSQVWYKV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEECCCCCCCHHHHHHHHH
GSSYETPGQTGLSHALEHMMFKGSEKVGPGEASLILRDLGAEENAFTSDDFTAYYQVLAR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
DRLGVAFELEADRMANLRLPADEFAKEIEVIKEERRLRTDDKPMAKAYERYKAMAYPASG
HCCCEEEEECHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
YHTPTIGWMADLERMKVEELRHWYQSWYVPNNATLVVVGDVTPDEVKTLAQRYFGPIPKR
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCC
DVPPAKKPLELAEPGERQITLHVQTQLPSLMLGFNVPSIATAEDKRSVNALRLISALLDG
CCCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
GYSGRIPTQLERGEELVSGGSSSYDAYTRGDSLFTLSATPNTQKKKTMAQAEAGLWKLLE
CCCCCCCHHHHHHHHHHCCCCCCCCCEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
QLKTSAPSAEELERVRAQVIAGLVFERDSITSQATAIGQLETVGLSWKLMDTELADLESV
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCEEEEECCHHHHHHCC
TPQDIQNAAKLYFTRERLSVAHVLPLETTHE
CHHHHHHHHHHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]