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The map label for this gene is gcp [H]

Identifier: 77461367

GI number: 77461367

Start: 5781873

End: 5782898

Strand: Reverse

Name: gcp [H]

Synonym: Pfl01_5146

Alternate gene names: 77461367

Gene position: 5782898-5781873 (Counterclockwise)

Preceding gene: 77461384

Following gene: 77461365

Centisome position: 89.82

GC content: 62.67

Gene sequence:

>1026_bases
ATGCTAGTACTGGGATTAGAAACTTCCTGCGACGAAACCGGCGTCGCTTTGTACGACAGCGAGCGCGGACTGCTGGCCGA
CGCGCTGTTCAGTCAGATCGACCTGCACCGCGTCTATGGCGGCGTGGTGCCGGAGCTCGCTTCGCGCGACCACGTAAAGC
GCATGCTGCCCCTGATTCGTCAGGTGCTGGCCGAGGCCGACTGCGTGCCGACCGAAATCGACGCCATCGCCTACACCGCA
GGTCCCGGCCTGGTCGGGGCGCTGCTGGTGGGTGCTTCGTGTGCCCAGGCGCTGGCGTTTGCCTGGGGCATTCCGGCGCT
CGGCGTGCACCACATGGAAGGCCATTTGCTGGCGCCGATGCTGGAGCCAAAACCGCCGGAATTTCCGTTCGTCGCTTTGT
TGGTGTCCGGTGGTCATACGCAGCTGGTTCAGGTCGATGGCATCGGCCAATACAGTCTGCTCGGCGAGACGCTGGATGAT
GCCGCGGGCGAAGCTTTCGACAAGACTGCAAAAATGATGGGCCTGAATTATCCGGGCGGTCCGGAAATCGCCAAGCTGGC
AGAGAAGGGTGTCGCAGGACGTTTCACCTTCCCGCGTCCGATGTGTGATCGCCCGGGTCTGGATTTCAGCTTCAGCGGCC
TGAAGACCTTCGCCCTCAACACCTGGCAGCAATGCGTCAGCGCCGGGGACGACAGCGAGCAAGCCCGTTGCGACATCGCG
CTGGCGTTCCAGCAGGCCGTGGTGGAGACTTTGACCATCAAGTGCAAGCGTGCCCTGAAGCAGGCCGGCATGAAGCGTCT
GGTGATCGCCGGAGGCGTCAGTGCCAACAGGGCGCTGCGTGTTTCGCTGGAGAAGATGCTCGGCGACATGAAGGGCGATG
TGTTCTATGCCCGTCCCGAGTTTTGCACCGATAACGGCGCAATGATTGCGTTTGCCGGCTGCCAGCGTTTGCAGGCCGGC
CAGCAGGAAAGCCTGGCGATCAGCGTACAGGCGCGCTGGCCGATGGAGCAATTGTCAGCGCTGTGA

Upstream 100 bases:

>100_bases
GCTCGGAATGCAAAGCCTCTGATCGAAAACCGCTGGTCGGGGCATCACGCGGCGACTATTATGCGCGCCTTCGAATTCAG
CCTAAACAAGGCGCAAACCC

Downstream 100 bases:

>100_bases
TAAGCAGCGCTCACATGCGGTATTTAAAAATGCCGTTCGCGCCCGGCGAACAGGTCGCGTAGATTGCCCCGGTGGCGCCA
GACGATCAGCAGTGTCAGCG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MLVLGLETSCDETGVALYDSERGLLADALFSQIDLHRVYGGVVPELASRDHVKRMLPLIRQVLAEADCVPTEIDAIAYTA
GPGLVGALLVGASCAQALAFAWGIPALGVHHMEGHLLAPMLEPKPPEFPFVALLVSGGHTQLVQVDGIGQYSLLGETLDD
AAGEAFDKTAKMMGLNYPGGPEIAKLAEKGVAGRFTFPRPMCDRPGLDFSFSGLKTFALNTWQQCVSAGDDSEQARCDIA
LAFQQAVVETLTIKCKRALKQAGMKRLVIAGGVSANRALRVSLEKMLGDMKGDVFYARPEFCTDNGAMIAFAGCQRLQAG
QQESLAISVQARWPMEQLSAL

Sequences:

>Translated_341_residues
MLVLGLETSCDETGVALYDSERGLLADALFSQIDLHRVYGGVVPELASRDHVKRMLPLIRQVLAEADCVPTEIDAIAYTA
GPGLVGALLVGASCAQALAFAWGIPALGVHHMEGHLLAPMLEPKPPEFPFVALLVSGGHTQLVQVDGIGQYSLLGETLDD
AAGEAFDKTAKMMGLNYPGGPEIAKLAEKGVAGRFTFPRPMCDRPGLDFSFSGLKTFALNTWQQCVSAGDDSEQARCDIA
LAFQQAVVETLTIKCKRALKQAGMKRLVIAGGVSANRALRVSLEKMLGDMKGDVFYARPEFCTDNGAMIAFAGCQRLQAG
QQESLAISVQARWPMEQLSAL
>Mature_341_residues
MLVLGLETSCDETGVALYDSERGLLADALFSQIDLHRVYGGVVPELASRDHVKRMLPLIRQVLAEADCVPTEIDAIAYTA
GPGLVGALLVGASCAQALAFAWGIPALGVHHMEGHLLAPMLEPKPPEFPFVALLVSGGHTQLVQVDGIGQYSLLGETLDD
AAGEAFDKTAKMMGLNYPGGPEIAKLAEKGVAGRFTFPRPMCDRPGLDFSFSGLKTFALNTWQQCVSAGDDSEQARCDIA
LAFQQAVVETLTIKCKRALKQAGMKRLVIAGGVSANRALRVSLEKMLGDMKGDVFYARPEFCTDNGAMIAFAGCQRLQAG
QQESLAISVQARWPMEQLSAL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=338, Percent_Identity=34.3195266272189, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI8923380, Length=348, Percent_Identity=30.1724137931034, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI1789445, Length=340, Percent_Identity=68.2352941176471, Blast_Score=485, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI17557464, Length=323, Percent_Identity=30.030959752322, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71995670, Length=349, Percent_Identity=30.0859598853868, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320099, Length=367, Percent_Identity=34.0599455040872, Blast_Score=166, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6322891, Length=355, Percent_Identity=29.5774647887324, Blast_Score=112, Evalue=6e-26,
Organism=Drosophila melanogaster, GI20129063, Length=351, Percent_Identity=34.7578347578348, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21357207, Length=334, Percent_Identity=29.3413173652695, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36426; Mature: 36426

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLGLETSCDETGVALYDSERGLLADALFSQIDLHRVYGGVVPELASRDHVKRMLPLIR
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
QVLAEADCVPTEIDAIAYTAGPGLVGALLVGASCAQALAFAWGIPALGVHHMEGHLLAPM
HHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCC
LEPKPPEFPFVALLVSGGHTQLVQVDGIGQYSLLGETLDDAAGEAFDKTAKMMGLNYPGG
CCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PEIAKLAEKGVAGRFTFPRPMCDRPGLDFSFSGLKTFALNTWQQCVSAGDDSEQARCDIA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
LAFQQAVVETLTIKCKRALKQAGMKRLVIAGGVSANRALRVSLEKMLGDMKGDVFYARPE
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCC
FCTDNGAMIAFAGCQRLQAGQQESLAISVQARWPMEQLSAL
EECCCCCEEEEECHHHHHCCCCCCEEEEEEECCCHHHHHCC
>Mature Secondary Structure
MLVLGLETSCDETGVALYDSERGLLADALFSQIDLHRVYGGVVPELASRDHVKRMLPLIR
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
QVLAEADCVPTEIDAIAYTAGPGLVGALLVGASCAQALAFAWGIPALGVHHMEGHLLAPM
HHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCC
LEPKPPEFPFVALLVSGGHTQLVQVDGIGQYSLLGETLDDAAGEAFDKTAKMMGLNYPGG
CCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PEIAKLAEKGVAGRFTFPRPMCDRPGLDFSFSGLKTFALNTWQQCVSAGDDSEQARCDIA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
LAFQQAVVETLTIKCKRALKQAGMKRLVIAGGVSANRALRVSLEKMLGDMKGDVFYARPE
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCC
FCTDNGAMIAFAGCQRLQAGQQESLAISVQARWPMEQLSAL
EECCCCCEEEEECHHHHHCCCCCCEEEEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA