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The map label for this gene is apaH

Identifier: 77461358

GI number: 77461358

Start: 5772499

End: 5773380

Strand: Direct

Name: apaH

Synonym: Pfl01_5137

Alternate gene names: 77461358

Gene position: 5772499-5773380 (Clockwise)

Preceding gene: 77461357

Following gene: 77461359

Centisome position: 89.66

GC content: 63.15

Gene sequence:

>882_bases
ATGGCGACGTATGCCGTCGGCGACCTCCAAGGCTGCCTCGAACCGCTCAAGTGCCTGCTCCAGCAGGTCGCGTTCGACCC
GGCTCTGGATCGCCTGTGGCTGGTCGGCGATCTGGTCAATCGTGGTCCGCAGTCACTGGAAACCCTGCGCTTCCTTTATG
GCATGCGCGAGTCGCTGGTCTGCGTTCTCGGCAATCACGACCTGCACCTGCTGGCAGCGGCGAAGAACATCGAGCGCCTG
AAGAAGTCCGACACGCTGCGTGAAATCCTTGAAGCGCCCGACTGCGCCGAACTGATGGAATGGCTGCGCCAGCAAAAACT
CATGCACTACGACGAGCAGCGCGAAGTGGCCATGGTACATGCGGGCATCCCGCCGCAGTGGTCGCTGCGCAAGGCGCTCA
AGTACGCTGAAGAAGTCGAGACCGCGCTGCGTGACGACAACCTTCTTCCACCCTTCCTCGACGGTATGTACGGCAACGAG
CCGGCGAAATGGGACAGCGACCTCAAAGGCGTGACACGCCTGCGGGTGATCACCAATTATTTCACCCGCATGCGTTTCTG
CACCGCCGAAGGCAAGCTCGACCTCAAGAGCAAGGAAGGCCTCGACACCGCGCCGCCGGGCTACAAGCCCTGGTTCCAGC
ACAAGGAGCGCAAGACCCGTGGCCTGCGGATCATTTTCGGTCACTGGGCCGCGCTGGAAGGCAACGTCCACGAGCCCGGC
ATCTGCGCCCTCGACACCGGTTGCGTCTGGGGCGGCAGCCTGACCCTGATGAATGTCGACAGCGGCGAACGGCTGTCATG
CAAATGCGACGAACACGGGGCCGCCCTGCCCACCGTCGCACCACTGATCACCGAATCTTCTCCCGTCAGCGCCCCGCGCT
AG

Upstream 100 bases:

>100_bases
GCACCATGCAAGGCAGTTACGAAATGGTCGCCGACGACGGCAAGCACTTCGATGCGATCATCAAGCCCTTCCGCCTCGCC
GTTCCCGGAGCCCTGCACTG

Downstream 100 bases:

>100_bases
ACTGCGTTTTCAGCCGAGCCAAAGGAGCCCGCCATGAGCGAATTCAAACGTATCCCCCCGGAACAGGCCCAGGCCCTGCG
CGAACAAGGCGCCGTGGTCG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MATYAVGDLQGCLEPLKCLLQQVAFDPALDRLWLVGDLVNRGPQSLETLRFLYGMRESLVCVLGNHDLHLLAAAKNIERL
KKSDTLREILEAPDCAELMEWLRQQKLMHYDEQREVAMVHAGIPPQWSLRKALKYAEEVETALRDDNLLPPFLDGMYGNE
PAKWDSDLKGVTRLRVITNYFTRMRFCTAEGKLDLKSKEGLDTAPPGYKPWFQHKERKTRGLRIIFGHWAALEGNVHEPG
ICALDTGCVWGGSLTLMNVDSGERLSCKCDEHGAALPTVAPLITESSPVSAPR

Sequences:

>Translated_293_residues
MATYAVGDLQGCLEPLKCLLQQVAFDPALDRLWLVGDLVNRGPQSLETLRFLYGMRESLVCVLGNHDLHLLAAAKNIERL
KKSDTLREILEAPDCAELMEWLRQQKLMHYDEQREVAMVHAGIPPQWSLRKALKYAEEVETALRDDNLLPPFLDGMYGNE
PAKWDSDLKGVTRLRVITNYFTRMRFCTAEGKLDLKSKEGLDTAPPGYKPWFQHKERKTRGLRIIFGHWAALEGNVHEPG
ICALDTGCVWGGSLTLMNVDSGERLSCKCDEHGAALPTVAPLITESSPVSAPR
>Mature_292_residues
ATYAVGDLQGCLEPLKCLLQQVAFDPALDRLWLVGDLVNRGPQSLETLRFLYGMRESLVCVLGNHDLHLLAAAKNIERLK
KSDTLREILEAPDCAELMEWLRQQKLMHYDEQREVAMVHAGIPPQWSLRKALKYAEEVETALRDDNLLPPFLDGMYGNEP
AKWDSDLKGVTRLRVITNYFTRMRFCTAEGKLDLKSKEGLDTAPPGYKPWFQHKERKTRGLRIIFGHWAALEGNVHEPGI
CALDTGCVWGGSLTLMNVDSGERLSCKCDEHGAALPTVAPLITESSPVSAPR

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family

Homologues:

Organism=Escherichia coli, GI1786234, Length=272, Percent_Identity=49.2647058823529, Blast_Score=265, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APAH_PSEPF (Q3K5T0)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_350865.1
- ProteinModelPortal:   Q3K5T0
- SMR:   Q3K5T0
- STRING:   Q3K5T0
- GeneID:   3717268
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_5137
- eggNOG:   COG0639
- HOGENOM:   HBG724457
- OMA:   LVFGHWA
- ProtClustDB:   PRK00166
- BioCyc:   PFLU205922:PFL_5137-MONOMER
- HAMAP:   MF_00199
- InterPro:   IPR004617
- InterPro:   IPR004843
- PIRSF:   PIRSF000903
- TIGRFAMs:   TIGR00668

Pfam domain/function: PF00149 Metallophos

EC number: =3.6.1.41

Molecular weight: Translated: 32882; Mature: 32751

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYAVGDLQGCLEPLKCLLQQVAFDPALDRLWLVGDLVNRGPQSLETLRFLYGMRESLV
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEE
CVLGNHDLHLLAAAKNIERLKKSDTLREILEAPDCAELMEWLRQQKLMHYDEQREVAMVH
EEECCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
AGIPPQWSLRKALKYAEEVETALRDDNLLPPFLDGMYGNEPAKWDSDLKGVTRLRVITNY
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
FTRMRFCTAEGKLDLKSKEGLDTAPPGYKPWFQHKERKTRGLRIIFGHWAALEGNVHEPG
HHHHHHEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEEEECCCCCCCC
ICALDTGCVWGGSLTLMNVDSGERLSCKCDEHGAALPTVAPLITESSPVSAPR
EEEEECCCEECCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ATYAVGDLQGCLEPLKCLLQQVAFDPALDRLWLVGDLVNRGPQSLETLRFLYGMRESLV
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEE
CVLGNHDLHLLAAAKNIERLKKSDTLREILEAPDCAELMEWLRQQKLMHYDEQREVAMVH
EEECCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
AGIPPQWSLRKALKYAEEVETALRDDNLLPPFLDGMYGNEPAKWDSDLKGVTRLRVITNY
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
FTRMRFCTAEGKLDLKSKEGLDTAPPGYKPWFQHKERKTRGLRIIFGHWAALEGNVHEPG
HHHHHHEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEEEECCCCCCCC
ICALDTGCVWGGSLTLMNVDSGERLSCKCDEHGAALPTVAPLITESSPVSAPR
EEEEECCCEECCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA