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The map label for this gene is rfbD [C]

Identifier: 77461252

GI number: 77461252

Start: 5663278

End: 5664162

Strand: Reverse

Name: rfbD [C]

Synonym: Pfl01_5031

Alternate gene names: 77461252

Gene position: 5664162-5663278 (Counterclockwise)

Preceding gene: 77461254

Following gene: 77461251

Centisome position: 87.97

GC content: 65.54

Gene sequence:

>885_bases
ATGCGAATGCGCCTTATGTTACTGGGCGGCGGAAATGCCCTTGGGCAGGCGCTGATTCGCCTCGGTGCAGAGGAAGACAT
CGGTTTCCTCGCCCCCCGCCCGCCCGAAGACGGCTGGGATGCCGCGAGCCTGACCCAATTGCTCGACGACACCCGTCCCG
ATGCATTGATCAACCTTGCCTACTATTTCGACTGGTTCCAGGCCGAGGCCGTCAGCGAAAGCCGTCTGGCCGGACAGGAA
CGCGCGATCGAGCGTCTGGCCGAACTGTGCCAGCACCACAACATCGTGCTGGTGCAGCCGTCCAGTTATCGGGTGTTCGA
CGGTTCCCGCGCCACTGCCTACAGCGAAAAGGACGAGCCAGTGCCGCTGGGCCTGCGCGGCCAGGCGCTGTGGCGGATCG
AGCAGAGCGTACGCGCCACCTGTCCGCAACATGTGCTGCTGCGTTTCGGCTGGCTGCTCGACGACAGCCCGGAAGGAATA
CTCGGACGCTTCCTGGCCCGTGCCGAACAACCGGAAGAATTGCTGCTGGCCGATGACCGCCGTGGCAATCCAACCCCGGT
CGACGATGCGGCGCGGGTGATCATTTCGGTGCTCAAGCAACTCGATTGCGCTGCGCCGCTGTGGGGCACTTACCACTACG
CCGGCCACGAGGCGACCACGCCGCTGGCGCTGGGCCAGGCGATTCTCTCCGAAGCGCGCAGCCTGCACCCGCTGGCCATC
GAAGCCCCGACCGCCCAGGCCCACGCCGCGCGCCCGGATGCCGCCGAAGAACCGCAACACGCGGTGCTCGCCTGCAAGAA
AATTCTGCACACCTTCGGGATCAAGCCGCGCGCCTGGCGTGCCGCGCTCCCGGGCTTACTGGATAGGTTTTATCGTCATG
GCTGA

Upstream 100 bases:

>100_bases
TAAACCCGCAAAATGCAACGATTCCGGCAATTATCGACGACGCTGCCACGAGCATCGTCGCCAAAGCCATCGTTCCAATC
AGACTGGGCCTGCTGACTCT

Downstream 100 bases:

>100_bases
AGGCCCTGTTCTCATCACCGGCGGCGCCGGTTTCATCGGCTCGCACCTGACTGACGCGCTGCTTGCAAAGGGCCATTCGG
TGCGGATTCTCGATGATCTG

Product: dTDP-4-dehydrorhamnose reductase

Products: NA

Alternate protein names: dTDP-4-keto-L-rhamnose reductase; dTDP-6-deoxy-L-lyxo-4-hexulose reductase; dTDP-6-deoxy-L-mannose dehydrogenase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MRMRLMLLGGGNALGQALIRLGAEEDIGFLAPRPPEDGWDAASLTQLLDDTRPDALINLAYYFDWFQAEAVSESRLAGQE
RAIERLAELCQHHNIVLVQPSSYRVFDGSRATAYSEKDEPVPLGLRGQALWRIEQSVRATCPQHVLLRFGWLLDDSPEGI
LGRFLARAEQPEELLLADDRRGNPTPVDDAARVIISVLKQLDCAAPLWGTYHYAGHEATTPLALGQAILSEARSLHPLAI
EAPTAQAHAARPDAAEEPQHAVLACKKILHTFGIKPRAWRAALPGLLDRFYRHG

Sequences:

>Translated_294_residues
MRMRLMLLGGGNALGQALIRLGAEEDIGFLAPRPPEDGWDAASLTQLLDDTRPDALINLAYYFDWFQAEAVSESRLAGQE
RAIERLAELCQHHNIVLVQPSSYRVFDGSRATAYSEKDEPVPLGLRGQALWRIEQSVRATCPQHVLLRFGWLLDDSPEGI
LGRFLARAEQPEELLLADDRRGNPTPVDDAARVIISVLKQLDCAAPLWGTYHYAGHEATTPLALGQAILSEARSLHPLAI
EAPTAQAHAARPDAAEEPQHAVLACKKILHTFGIKPRAWRAALPGLLDRFYRHG
>Mature_294_residues
MRMRLMLLGGGNALGQALIRLGAEEDIGFLAPRPPEDGWDAASLTQLLDDTRPDALINLAYYFDWFQAEAVSESRLAGQE
RAIERLAELCQHHNIVLVQPSSYRVFDGSRATAYSEKDEPVPLGLRGQALWRIEQSVRATCPQHVLLRFGWLLDDSPEGI
LGRFLARAEQPEELLLADDRRGNPTPVDDAARVIISVLKQLDCAAPLWGTYHYAGHEATTPLALGQAILSEARSLHPLAI
EAPTAQAHAARPDAAEEPQHAVLACKKILHTFGIKPRAWRAALPGLLDRFYRHG

Specific function: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose. RmlD uses NADH and NADPH nearly equally well [H]

COG id: COG1091

COG function: function code M; dTDP-4-dehydrorhamnose reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose reductase family [H]

Homologues:

Organism=Escherichia coli, GI1788352, Length=253, Percent_Identity=23.7154150197628, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005913
- InterPro:   IPR016040 [H]

Pfam domain/function: PF04321 RmlD_sub_bind [H]

EC number: =1.1.1.133 [H]

Molecular weight: Translated: 32465; Mature: 32465

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMRLMLLGGGNALGQALIRLGAEEDIGFLAPRPPEDGWDAASLTQLLDDTRPDALINLA
CCEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
YYFDWFQAEAVSESRLAGQERAIERLAELCQHHNIVLVQPSSYRVFDGSRATAYSEKDEP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCCCCCCCCC
VPLGLRGQALWRIEQSVRATCPQHVLLRFGWLLDDSPEGILGRFLARAEQPEELLLADDR
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHEEECCC
RGNPTPVDDAARVIISVLKQLDCAAPLWGTYHYAGHEATTPLALGQAILSEARSLHPLAI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEE
EAPTAQAHAARPDAAEEPQHAVLACKKILHTFGIKPRAWRAALPGLLDRFYRHG
ECCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRMRLMLLGGGNALGQALIRLGAEEDIGFLAPRPPEDGWDAASLTQLLDDTRPDALINLA
CCEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
YYFDWFQAEAVSESRLAGQERAIERLAELCQHHNIVLVQPSSYRVFDGSRATAYSEKDEP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCCCCCCCCC
VPLGLRGQALWRIEQSVRATCPQHVLLRFGWLLDDSPEGILGRFLARAEQPEELLLADDR
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHEEECCC
RGNPTPVDDAARVIISVLKQLDCAAPLWGTYHYAGHEATTPLALGQAILSEARSLHPLAI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEE
EAPTAQAHAARPDAAEEPQHAVLACKKILHTFGIKPRAWRAALPGLLDRFYRHG
ECCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]