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The map label for this gene is galE [C]

Identifier: 77461251

GI number: 77461251

Start: 5662356

End: 5663285

Strand: Reverse

Name: galE [C]

Synonym: Pfl01_5030

Alternate gene names: 77461251

Gene position: 5663285-5662356 (Counterclockwise)

Preceding gene: 77461252

Following gene: 77461245

Centisome position: 87.96

GC content: 63.44

Gene sequence:

>930_bases
ATGGCTGAAGGCCCTGTTCTCATCACCGGCGGCGCCGGTTTCATCGGCTCGCACCTGACTGACGCGCTGCTTGCAAAGGG
CCATTCGGTGCGGATTCTCGATGATCTGTCGACCGGCAAGCGCAGCAACCTGCCGCTGGATAATCCCAAGGTCGAACTGA
TCGTCGGCGATGTGGCCGATGCTGCTCTGGTCGCACAAGCGATGCAGGGTTGCAGCGCGGTCGCCCATCTGGCCGCCGTC
GCTTCGGTGCAGGCGTCGGTGGACGATCCGGTGAAAACCCACCAGAGCAATTTCATCGGCACGCTGAACGTCTGCGAAGC
CATGCGCGAGGCCGGCGTGAAGCGTGTGTTGTACGCCTCCAGCGCAGCGGTCTACGGCAACAATGGCGAAGGCGAGTCGA
TTGACGAAGACACGCCCAAGGCACCGCTGACGCCTTACGCGTCGGACAAACTGGCCGGCGAGCAGTACTTCGATTTCTAC
CGCCGCCAGCACGGTCTGGAACCGGCGATCTTCCGTTTCTTCAACATCTTCGGACCGCGCCAGGATCCGTCCTCGCCGTA
CTCCGGGGTGATCAGCATTTTCAGCGAACGCGCGCAGAAAGGCCTGCCGATCACCGTGTTCGGCGATGGCGAGCAGACCC
GGGATTTCATGTACGTCGAAGACCTGGTCGATGTCCTGGTGCAGGCGCTCGAAAAGCCGCAAGTGGATGTCGGTGCGGTG
AACGTCGGCTGGAATCAGGCGACCAACCTCAAGCAGATGCTGGCCGCGCTCGAAGCGGTGGTCGGCGAGTTGCCGCCCGT
CAGCTACGGCCCGGCGCGCTCCGGTGACATCCGTCATTCGCGGGCGAACAACCGCCGGTTGCTTGAGCGATTCAAGTGCC
CCACGCCAACGCCGATGAACGTCGGCCTGGCCCGTCTGCTCGGCCGCTGA

Upstream 100 bases:

>100_bases
CACGCGGTGCTCGCCTGCAAGAAAATTCTGCACACCTTCGGGATCAAGCCGCGCGCCTGGCGTGCCGCGCTCCCGGGCTT
ACTGGATAGGTTTTATCGTC

Downstream 100 bases:

>100_bases
GCTTCTTGCGGACATGAAAAAGGCGCCTTTTGACAGGCGCCTTTTTCACGGCCGGAATTCGGCTTTCAAACCGGTTTCCT
GTAGCGAGGGAGCTTGCTCC

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAEGPVLITGGAGFIGSHLTDALLAKGHSVRILDDLSTGKRSNLPLDNPKVELIVGDVADAALVAQAMQGCSAVAHLAAV
ASVQASVDDPVKTHQSNFIGTLNVCEAMREAGVKRVLYASSAAVYGNNGEGESIDEDTPKAPLTPYASDKLAGEQYFDFY
RRQHGLEPAIFRFFNIFGPRQDPSSPYSGVISIFSERAQKGLPITVFGDGEQTRDFMYVEDLVDVLVQALEKPQVDVGAV
NVGWNQATNLKQMLAALEAVVGELPPVSYGPARSGDIRHSRANNRRLLERFKCPTPTPMNVGLARLLGR

Sequences:

>Translated_309_residues
MAEGPVLITGGAGFIGSHLTDALLAKGHSVRILDDLSTGKRSNLPLDNPKVELIVGDVADAALVAQAMQGCSAVAHLAAV
ASVQASVDDPVKTHQSNFIGTLNVCEAMREAGVKRVLYASSAAVYGNNGEGESIDEDTPKAPLTPYASDKLAGEQYFDFY
RRQHGLEPAIFRFFNIFGPRQDPSSPYSGVISIFSERAQKGLPITVFGDGEQTRDFMYVEDLVDVLVQALEKPQVDVGAV
NVGWNQATNLKQMLAALEAVVGELPPVSYGPARSGDIRHSRANNRRLLERFKCPTPTPMNVGLARLLGR
>Mature_308_residues
AEGPVLITGGAGFIGSHLTDALLAKGHSVRILDDLSTGKRSNLPLDNPKVELIVGDVADAALVAQAMQGCSAVAHLAAVA
SVQASVDDPVKTHQSNFIGTLNVCEAMREAGVKRVLYASSAAVYGNNGEGESIDEDTPKAPLTPYASDKLAGEQYFDFYR
RQHGLEPAIFRFFNIFGPRQDPSSPYSGVISIFSERAQKGLPITVFGDGEQTRDFMYVEDLVDVLVQALEKPQVDVGAVN
VGWNQATNLKQMLAALEAVVGELPPVSYGPARSGDIRHSRANNRRLLERFKCPTPTPMNVGLARLLGR

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=264, Percent_Identity=36.7424242424242, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI7657641, Length=266, Percent_Identity=31.203007518797, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI56237023, Length=317, Percent_Identity=29.9684542586751, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI56118217, Length=317, Percent_Identity=29.9684542586751, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI189083684, Length=317, Percent_Identity=29.9684542586751, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI193211614, Length=238, Percent_Identity=30.672268907563, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI8393516, Length=238, Percent_Identity=30.672268907563, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1786974, Length=296, Percent_Identity=31.4189189189189, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI48994969, Length=288, Percent_Identity=28.8194444444444, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788353, Length=289, Percent_Identity=27.681660899654, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788589, Length=272, Percent_Identity=27.2058823529412, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788366, Length=241, Percent_Identity=28.2157676348548, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790049, Length=259, Percent_Identity=29.7297297297297, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=315, Percent_Identity=30.7936507936508, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17568069, Length=248, Percent_Identity=31.0483870967742, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71982038, Length=305, Percent_Identity=27.8688524590164, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982035, Length=312, Percent_Identity=27.8846153846154, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115532424, Length=280, Percent_Identity=25.7142857142857, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17570557, Length=186, Percent_Identity=31.1827956989247, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=325, Percent_Identity=26.1538461538462, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356223, Length=309, Percent_Identity=30.0970873786408, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI19923002, Length=308, Percent_Identity=28.8961038961039, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24158427, Length=241, Percent_Identity=26.5560165975104, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 33147; Mature: 33016

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGPVLITGGAGFIGSHLTDALLAKGHSVRILDDLSTGKRSNLPLDNPKVELIVGDVAD
CCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCHHH
AALVAQAMQGCSAVAHLAAVASVQASVDDPVKTHQSNFIGTLNVCEAMREAGVKRVLYAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHC
SAAVYGNNGEGESIDEDTPKAPLTPYASDKLAGEQYFDFYRRQHGLEPAIFRFFNIFGPR
CEEEECCCCCCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHCCCCHHHHHHHHHCCCC
QDPSSPYSGVISIFSERAQKGLPITVFGDGEQTRDFMYVEDLVDVLVQALEKPQVDVGAV
CCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
NVGWNQATNLKQMLAALEAVVGELPPVSYGPARSGDIRHSRANNRRLLERFKCPTPTPMN
ECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCHHHHHHHHCCCCCCCCH
VGLARLLGR
HHHHHHHCC
>Mature Secondary Structure 
AEGPVLITGGAGFIGSHLTDALLAKGHSVRILDDLSTGKRSNLPLDNPKVELIVGDVAD
CCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCHHH
AALVAQAMQGCSAVAHLAAVASVQASVDDPVKTHQSNFIGTLNVCEAMREAGVKRVLYAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHC
SAAVYGNNGEGESIDEDTPKAPLTPYASDKLAGEQYFDFYRRQHGLEPAIFRFFNIFGPR
CEEEECCCCCCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHCCCCHHHHHHHHHCCCC
QDPSSPYSGVISIFSERAQKGLPITVFGDGEQTRDFMYVEDLVDVLVQALEKPQVDVGAV
CCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
NVGWNQATNLKQMLAALEAVVGELPPVSYGPARSGDIRHSRANNRRLLERFKCPTPTPMN
ECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCHHHHHHHHCCCCCCCCH
VGLARLLGR
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]