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The map label for this gene is rpfC [H]

Identifier: 77461165

GI number: 77461165

Start: 5570752

End: 5573100

Strand: Reverse

Name: rpfC [H]

Synonym: Pfl01_4944

Alternate gene names: 77461165

Gene position: 5573100-5570752 (Counterclockwise)

Preceding gene: 77461170

Following gene: 77461164

Centisome position: 86.56

GC content: 62.84

Gene sequence:

>2349_bases
ATGCGCTATTTGTTGATGTTGCTGTTCTGCTTGCCCCTCCTGGCAAGCGCCGTCGAGTTCGACGAGTTCACCCAGAGCCT
CCCCCTGGGTCGATCCCTGCAAGTGTTCGAAGACCCGAGCGGTCAGGCGAGCATTGCCGACGTCCGCGCGCAAGCCGCCG
CCGGAAACTTCAAACCCCATGACAAAGCCACGCTCAATGCCGGTTATTCGCGCTCGGCGTTCTGGCTGAAGATCGACCTG
CATTACCGCCCGACCAATCCGTCGGCGCAGCGCAGCTGGTTGCTGGAGCTGGCGTATCCGCCGCTCGATCATCTCGACCT
GTATCTGCCCGATGCGGCCGGCGACTACCGTCTGGTGCGGCAGACCGGGGACGCCTTGCCGTTCGCCAGTCGCGAAATCC
GCCAGAACAATTACCTGTTCGACCTGGCGTTCAAGCCGGATCAGCAGCGAACCGTTTATCTGCGGTTGTCCAGCGAAGGC
TCGATCCAGGCGCCGATGACGTTGTGGTCGAGCACCGCGTACCTCGAAGACCAGCCGGTGCGCCTGTACGTGCTGGGGGT
CATCTATGGCGTGCTGCTGGGGATGCTGGTCTATAACCTGTTCATCTACCTCAGCGTGCGCGATACCAGTTACCTCTATT
ACATCTTCTATATCGCTTCGTTCGGCCTCTATCAGCTGTCGGTCAATGGCGCGGCGGTCGAGTATTTCTGGCCGGACAAC
CCATGGTGGGCCAACGCCGCCACGCCGTTCTTCATCGGTTGCGCGGGGCTGTTCGGCAGCCAGTTCGCCCGCAGTTTCCT
GCAGACCAGGAACCACAGCCGCTGGCTCGATCGCCTGCTGATCGCCCTGATCGCGTTCGGCGCCATGGTGATCGGCCTCT
CGTTGATGACCAGTTATGGCCTGGCCCTGCGTCTGGCGACGACCCTGGCGCTGACCTTCACCGTGGTGATCTTTGCCGCC
GGGATCCTCGCCTGGTGGCGCGGCCTGCGGGTGGCGCGTTATTTCATCATTGCCTGGTCGGCGTTCCTGATCGGCGGCAT
CGTCAACACCATGATGGTGCTGGGCCTGCTGCCGAATGTGTTCCTGACCATGTACGCCAGCCAGATCGGTTCGGCCATTG
AAGTGGCGCTGCTGTCGCTGGCGCTGGCCGACCGCATCAACGCGATGCGCGAACAACAGGCGCAGACCCTGTTCGATGCG
GGCCAGAAGCTCGAAGTGCTCAACCAGCAACTGGCCCATAGCAACAAGCTCAAGGACGAATTCCTCGCGACCCTGACTCA
CGAACTGCGCACGCCGATGAACGGTGTGATCGGTTCGCTGGAGCTGATGCAGACCGTCGAACTCGATCCGGAGCTGGAGC
AATACCAGCAGACCGCCGCCGGTTCGGCGCGGGACATGATGCGCATGGTCAACGGCATCCTGACCCTGACCGAATTGCAG
GCCGGCAAGCTCAAGGCCACACCGGGCAGTTTCAGCCTGCGCGGGGTGGTCGAGGCGTTGCGGATGCAGTTCGATGGCAA
CGCTTCGAGCAAGTCGCTGGACTTCAAGGTCGACGTGCTGCCGACCCTGCCGGATCGCCTGCATGGCGACAGCGCCAAAC
TCGCGCAATGCCTGGAGTGCCTGCTGGACAACGCGATCAAGTTCACCCGCGTCGGCGGTCTGGCATTGCGGGTCACCGGC
AAACCGTCCACGGACAATCGGCTGGCGCTGTCCTTCGCGGTGATCGACACCGGCATCGGTTTTACCGATCTGGGCGAGGC
CACGCTGTATCAGCGGTTCTTCCAGCTCGACGGTTCGATGACCCGCGAATACGGCGGGCTGGGTGTCGGTCTGGCGATCT
GCCGTCAATTGGTGGAACTGCTCGGCGGCAAGCTCACGCACCGTTCCGAACCGGGGAGTGGCAGCCGCTTTCAACTGGAT
GTCGAGTTTGAGTTGCCGGAAGTGGAAGCCGTGCCCGCGTTCAGCCGCGACACCGTGCGTGCGCCGCAGGATTGCACCGT
GTTGCTGGTGGACGACAACAGCGTCAATCAATTGGTGATGCGCGGCATGTTGCTCAAGCTCGGTTTCCGGGTGCGCACCG
CCGACCACGGCGCGGCGGCGCTCGACTGTTTGCAGCGCGAGCGCTTCGATGCCGTGCTGATCGACTGCCAGCTGCCACCG
CTCGACGGGGCATCGCTGTGTTGCCAGATCCGTGACCTGCCGGGATGCGCCCATCTGCCGGTGTTCATGATCGCGCTGGG
GGCGGATCGCGAGCATTGTGCGTCGGGTGGCTCGATCGACTACCTGAGCAAACCGGTGAAATTCGAGGATCTGCAGGTGG
CGATGCAGCGGCGGGTGTTGAGTTGCTGA

Upstream 100 bases:

>100_bases
GAGTGGATCCAAACCAATAACAGGTAATACCGGTTTTACGTCATCTCAAAGGGAATGGGGGGCTTCCTGACACAACCGGC
CAAGCCACGCTGGGGCTTCA

Downstream 100 bases:

>100_bases
CAGGGTGAAAGCGCCGGCATTTCGGCCGATATGACACTTTGATCGGTTCCGGTGCGGTGCTTAACTGAAGCTCTGGCCGA
TCAAGGAGCCCCGTCATGAA

Product: periplasmic sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 782; Mature: 782

Protein sequence:

>782_residues
MRYLLMLLFCLPLLASAVEFDEFTQSLPLGRSLQVFEDPSGQASIADVRAQAAAGNFKPHDKATLNAGYSRSAFWLKIDL
HYRPTNPSAQRSWLLELAYPPLDHLDLYLPDAAGDYRLVRQTGDALPFASREIRQNNYLFDLAFKPDQQRTVYLRLSSEG
SIQAPMTLWSSTAYLEDQPVRLYVLGVIYGVLLGMLVYNLFIYLSVRDTSYLYYIFYIASFGLYQLSVNGAAVEYFWPDN
PWWANAATPFFIGCAGLFGSQFARSFLQTRNHSRWLDRLLIALIAFGAMVIGLSLMTSYGLALRLATTLALTFTVVIFAA
GILAWWRGLRVARYFIIAWSAFLIGGIVNTMMVLGLLPNVFLTMYASQIGSAIEVALLSLALADRINAMREQQAQTLFDA
GQKLEVLNQQLAHSNKLKDEFLATLTHELRTPMNGVIGSLELMQTVELDPELEQYQQTAAGSARDMMRMVNGILTLTELQ
AGKLKATPGSFSLRGVVEALRMQFDGNASSKSLDFKVDVLPTLPDRLHGDSAKLAQCLECLLDNAIKFTRVGGLALRVTG
KPSTDNRLALSFAVIDTGIGFTDLGEATLYQRFFQLDGSMTREYGGLGVGLAICRQLVELLGGKLTHRSEPGSGSRFQLD
VEFELPEVEAVPAFSRDTVRAPQDCTVLLVDDNSVNQLVMRGMLLKLGFRVRTADHGAAALDCLQRERFDAVLIDCQLPP
LDGASLCCQIRDLPGCAHLPVFMIALGADREHCASGGSIDYLSKPVKFEDLQVAMQRRVLSC

Sequences:

>Translated_782_residues
MRYLLMLLFCLPLLASAVEFDEFTQSLPLGRSLQVFEDPSGQASIADVRAQAAAGNFKPHDKATLNAGYSRSAFWLKIDL
HYRPTNPSAQRSWLLELAYPPLDHLDLYLPDAAGDYRLVRQTGDALPFASREIRQNNYLFDLAFKPDQQRTVYLRLSSEG
SIQAPMTLWSSTAYLEDQPVRLYVLGVIYGVLLGMLVYNLFIYLSVRDTSYLYYIFYIASFGLYQLSVNGAAVEYFWPDN
PWWANAATPFFIGCAGLFGSQFARSFLQTRNHSRWLDRLLIALIAFGAMVIGLSLMTSYGLALRLATTLALTFTVVIFAA
GILAWWRGLRVARYFIIAWSAFLIGGIVNTMMVLGLLPNVFLTMYASQIGSAIEVALLSLALADRINAMREQQAQTLFDA
GQKLEVLNQQLAHSNKLKDEFLATLTHELRTPMNGVIGSLELMQTVELDPELEQYQQTAAGSARDMMRMVNGILTLTELQ
AGKLKATPGSFSLRGVVEALRMQFDGNASSKSLDFKVDVLPTLPDRLHGDSAKLAQCLECLLDNAIKFTRVGGLALRVTG
KPSTDNRLALSFAVIDTGIGFTDLGEATLYQRFFQLDGSMTREYGGLGVGLAICRQLVELLGGKLTHRSEPGSGSRFQLD
VEFELPEVEAVPAFSRDTVRAPQDCTVLLVDDNSVNQLVMRGMLLKLGFRVRTADHGAAALDCLQRERFDAVLIDCQLPP
LDGASLCCQIRDLPGCAHLPVFMIALGADREHCASGGSIDYLSKPVKFEDLQVAMQRRVLSC
>Mature_782_residues
MRYLLMLLFCLPLLASAVEFDEFTQSLPLGRSLQVFEDPSGQASIADVRAQAAAGNFKPHDKATLNAGYSRSAFWLKIDL
HYRPTNPSAQRSWLLELAYPPLDHLDLYLPDAAGDYRLVRQTGDALPFASREIRQNNYLFDLAFKPDQQRTVYLRLSSEG
SIQAPMTLWSSTAYLEDQPVRLYVLGVIYGVLLGMLVYNLFIYLSVRDTSYLYYIFYIASFGLYQLSVNGAAVEYFWPDN
PWWANAATPFFIGCAGLFGSQFARSFLQTRNHSRWLDRLLIALIAFGAMVIGLSLMTSYGLALRLATTLALTFTVVIFAA
GILAWWRGLRVARYFIIAWSAFLIGGIVNTMMVLGLLPNVFLTMYASQIGSAIEVALLSLALADRINAMREQQAQTLFDA
GQKLEVLNQQLAHSNKLKDEFLATLTHELRTPMNGVIGSLELMQTVELDPELEQYQQTAAGSARDMMRMVNGILTLTELQ
AGKLKATPGSFSLRGVVEALRMQFDGNASSKSLDFKVDVLPTLPDRLHGDSAKLAQCLECLLDNAIKFTRVGGLALRVTG
KPSTDNRLALSFAVIDTGIGFTDLGEATLYQRFFQLDGSMTREYGGLGVGLAICRQLVELLGGKLTHRSEPGSGSRFQLD
VEFELPEVEAVPAFSRDTVRAPQDCTVLLVDDNSVNQLVMRGMLLKLGFRVRTADHGAAALDCLQRERFDAVLIDCQLPP
LDGASLCCQIRDLPGCAHLPVFMIALGADREHCASGGSIDYLSKPVKFEDLQVAMQRRVLSC

Specific function: Involved in the positive regulation of synthesis of extracellular enzymes and polysaccharide, and hence in pathogenicity. Can restore function to the non-pathogenic mutant 8237 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=32.0610687022901, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI48994928, Length=363, Percent_Identity=31.129476584022, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1788713, Length=381, Percent_Identity=27.0341207349081, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=32.295719844358, Blast_Score=142, Evalue=9e-35,
Organism=Escherichia coli, GI87081816, Length=323, Percent_Identity=29.1021671826625, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788393, Length=249, Percent_Identity=28.5140562248996, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=28.0487804878049, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=26.2931034482759, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788279, Length=230, Percent_Identity=26.9565217391304, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1790861, Length=232, Percent_Identity=26.7241379310345, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86541; Mature: 86541

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLLMLLFCLPLLASAVEFDEFTQSLPLGRSLQVFEDPSGQASIADVRAQAAAGNFKPH
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCC
DKATLNAGYSRSAFWLKIDLHYRPTNPSAQRSWLLELAYPPLDHLDLYLPDAAGDYRLVR
CCCEECCCCCCCEEEEEEEEEEECCCCCHHHHEEEEECCCCCCCCEEECCCCCCCHHHHH
QTGDALPFASREIRQNNYLFDLAFKPDQQRTVYLRLSSEGSIQAPMTLWSSTAYLEDQPV
HCCCCCCCCHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCHHHHCCCCEECCCCC
RLYVLGVIYGVLLGMLVYNLFIYLSVRDTSYLYYIFYIASFGLYQLSVNGAAVEYFWPDN
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHCCEEEEEECCEEEEEECCCC
PWWANAATPFFIGCAGLFGSQFARSFLQTRNHSRWLDRLLIALIAFGAMVIGLSLMTSYG
CEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALRLATTLALTFTVVIFAAGILAWWRGLRVARYFIIAWSAFLIGGIVNTMMVLGLLPNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLTMYASQIGSAIEVALLSLALADRINAMREQQAQTLFDAGQKLEVLNQQLAHSNKLKDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHH
FLATLTHELRTPMNGVIGSLELMQTVELDPELEQYQQTAAGSARDMMRMVNGILTLTELQ
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHEECC
AGKLKATPGSFSLRGVVEALRMQFDGNASSKSLDFKVDVLPTLPDRLHGDSAKLAQCLEC
CCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHCCCHHHHHHHHHH
LLDNAIKFTRVGGLALRVTGKPSTDNRLALSFAVIDTGIGFTDLGEATLYQRFFQLDGSM
HHHCCHHEEEECCEEEEEECCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCH
TREYGGLGVGLAICRQLVELLGGKLTHRSEPGSGSRFQLDVEFELPEVEAVPAFSRDTVR
HHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCC
APQDCTVLLVDDNSVNQLVMRGMLLKLGFRVRTADHGAAALDCLQRERFDAVLIDCQLPP
CCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCEEEEEECCCC
LDGASLCCQIRDLPGCAHLPVFMIALGADREHCASGGSIDYLSKPVKFEDLQVAMQRRVL
CCCHHHEEEEECCCCCCCCHHHHHEECCCHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHC
SC
CC
>Mature Secondary Structure
MRYLLMLLFCLPLLASAVEFDEFTQSLPLGRSLQVFEDPSGQASIADVRAQAAAGNFKPH
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCC
DKATLNAGYSRSAFWLKIDLHYRPTNPSAQRSWLLELAYPPLDHLDLYLPDAAGDYRLVR
CCCEECCCCCCCEEEEEEEEEEECCCCCHHHHEEEEECCCCCCCCEEECCCCCCCHHHHH
QTGDALPFASREIRQNNYLFDLAFKPDQQRTVYLRLSSEGSIQAPMTLWSSTAYLEDQPV
HCCCCCCCCHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCHHHHCCCCEECCCCC
RLYVLGVIYGVLLGMLVYNLFIYLSVRDTSYLYYIFYIASFGLYQLSVNGAAVEYFWPDN
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHCCEEEEEECCEEEEEECCCC
PWWANAATPFFIGCAGLFGSQFARSFLQTRNHSRWLDRLLIALIAFGAMVIGLSLMTSYG
CEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALRLATTLALTFTVVIFAAGILAWWRGLRVARYFIIAWSAFLIGGIVNTMMVLGLLPNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLTMYASQIGSAIEVALLSLALADRINAMREQQAQTLFDAGQKLEVLNQQLAHSNKLKDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHH
FLATLTHELRTPMNGVIGSLELMQTVELDPELEQYQQTAAGSARDMMRMVNGILTLTELQ
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHEECC
AGKLKATPGSFSLRGVVEALRMQFDGNASSKSLDFKVDVLPTLPDRLHGDSAKLAQCLEC
CCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHCCCHHHHHHHHHH
LLDNAIKFTRVGGLALRVTGKPSTDNRLALSFAVIDTGIGFTDLGEATLYQRFFQLDGSM
HHHCCHHEEEECCEEEEEECCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCH
TREYGGLGVGLAICRQLVELLGGKLTHRSEPGSGSRFQLDVEFELPEVEAVPAFSRDTVR
HHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCC
APQDCTVLLVDDNSVNQLVMRGMLLKLGFRVRTADHGAAALDCLQRERFDAVLIDCQLPP
CCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCEEEEEECCCC
LDGASLCCQIRDLPGCAHLPVFMIALGADREHCASGGSIDYLSKPVKFEDLQVAMQRRVL
CCCHHHEEEEECCCCCCCCHHHHHEECCCHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHC
SC
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1645442 [H]