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The map label for this gene is lrp [H]

Identifier: 77461160

GI number: 77461160

Start: 5565950

End: 5566429

Strand: Direct

Name: lrp [H]

Synonym: Pfl01_4939

Alternate gene names: 77461160

Gene position: 5565950-5566429 (Clockwise)

Preceding gene: 77461158

Following gene: 77461161

Centisome position: 86.45

GC content: 60.62

Gene sequence:

>480_bases
ATGAGCAAACTCGACCGTTACGACCTGAGTATTTTGGCGGAATTGCAGCGCGACGCCCGCATCTCCAACCAGGAACTGGC
CGAGCGCATCGGTCTGTCGCCCTCCCCGTGCTCGCGCCGGGTCAAGCAACTGGAGGACGACGGTTACATCTCCCGTCAGG
TCGCCCTGCTCGATCGCAAGATGCTCGGCCTTAGCCTGACCGCCTACGTGCTGATCGGCATGGACCGGCACACGCCGGAG
CGTTTCGAGAATTTCGAAGCGGCGATCCGCACCTTGCCGCAAGTGCTGGAATGCAGCCTGGTGACTGGCGTGGATGCCGA
CTATCAGCTGAAAGTGGTGGTGCCGGACATGGATCACTATCAGAAGCTGCTGCTGGGGCATCTGACCCGGATCGAAGGCG
TAACCAGCGTGCGCTCGAGTTTTGTGCTGAATCAGGTGCTCAACAGCACCGAACTGCCGCTGACTCATCTGCGCAGCTGA

Upstream 100 bases:

>100_bases
CGACAGATGATTGCGAAGATTGCTCAAATAAACATCACTTGCGCAATTTTTAACCCTGGATAGATAATCCGCCGCAATAG
TTAAGACAAAGGACCGTTTG

Downstream 100 bases:

>100_bases
AATCGACGAATGACTGCGGCACACCGACGCAGGTCAATGCTGCGTCGTTCACCGCTGGCGTATACTCCCGGCCGCCCTTT
CAGCCGCGCAGCGCCGGAGA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSKLDRYDLSILAELQRDARISNQELAERIGLSPSPCSRRVKQLEDDGYISRQVALLDRKMLGLSLTAYVLIGMDRHTPE
RFENFEAAIRTLPQVLECSLVTGVDADYQLKVVVPDMDHYQKLLLGHLTRIEGVTSVRSSFVLNQVLNSTELPLTHLRS

Sequences:

>Translated_159_residues
MSKLDRYDLSILAELQRDARISNQELAERIGLSPSPCSRRVKQLEDDGYISRQVALLDRKMLGLSLTAYVLIGMDRHTPE
RFENFEAAIRTLPQVLECSLVTGVDADYQLKVVVPDMDHYQKLLLGHLTRIEGVTSVRSSFVLNQVLNSTELPLTHLRS
>Mature_158_residues
SKLDRYDLSILAELQRDARISNQELAERIGLSPSPCSRRVKQLEDDGYISRQVALLDRKMLGLSLTAYVLIGMDRHTPER
FENFEAAIRTLPQVLECSLVTGVDADYQLKVVVPDMDHYQKLLLGHLTRIEGVTSVRSSFVLNQVLNSTELPLTHLRS

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=149, Percent_Identity=47.6510067114094, Blast_Score=131, Evalue=2e-32,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=39.0728476821192, Blast_Score=111, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18023; Mature: 17892

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLDRYDLSILAELQRDARISNQELAERIGLSPSPCSRRVKQLEDDGYISRQVALLDRK
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
MLGLSLTAYVLIGMDRHTPERFENFEAAIRTLPQVLECSLVTGVDADYQLKVVVPDMDHY
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHH
QKLLLGHLTRIEGVTSVRSSFVLNQVLNSTELPLTHLRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
>Mature Secondary Structure 
SKLDRYDLSILAELQRDARISNQELAERIGLSPSPCSRRVKQLEDDGYISRQVALLDRK
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
MLGLSLTAYVLIGMDRHTPERFENFEAAIRTLPQVLECSLVTGVDADYQLKVVVPDMDHY
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHH
QKLLLGHLTRIEGVTSVRSSFVLNQVLNSTELPLTHLRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]