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The map label for this gene is ygjG [C]

Identifier: 77461153

GI number: 77461153

Start: 5556444

End: 5557814

Strand: Reverse

Name: ygjG [C]

Synonym: Pfl01_4932

Alternate gene names: 77461153

Gene position: 5557814-5556444 (Counterclockwise)

Preceding gene: 77461154

Following gene: 77461152

Centisome position: 86.32

GC content: 62.95

Gene sequence:

>1371_bases
ATGACCACCTCACGTGAAACCCGCGACTACCAGGCCGCCGATGCAGCGCACCACATTCATGCGTTCGTCGACCAGAAAGC
CCTCAACGACGAAGGCCCACGGGTGATGGTGCGTGGTGATCGCCTGCATCTGTGGGACAACGACGGTCGGCGCTACCTCG
ACGGCATGTCCGGGCTGTGGTGCACCAACCTCGGCTACGGGCGCAAGGATCTGAACGCCGCCGCGAGCCGGCAACTGGAG
CAGTTGCCGTACTACAACATGTTTTTCCACACCACCCACCCGCAGGTGATCGAGCTCTCCGAGCTGCTGTTCAGCCTGCT
GCCGGGGCACTACAGCCACGCGATCTACACCAACTCCGGCTCCGAGGCCAACGAGGTGCTGATCCGTACCGTACGCCGTT
ACTGGCAGGTGCTGGGCAAGCCCGAGAAGAAAATCATGATCGGCCGCTGGAACGGCTATCACGGTTCGACCCTGGCCGCG
ACGGCCCTCGGCGGCATGAAGTTCATGCACGAAATGGGCGGGATGATTCCCGACATCGCGCACATCGACGAGCCGTACTT
CTTCGCCCACGAAGGCAATCTGACCCCGGCGGAATTCGGTCTGCGGGCGGCGCAGCAACTGGAAGCGAAGATCCTCGAAC
TGGGCGCCGACAAGGTCGCCGGGTTCATCGCCGAACCGTTCCAGGGCGCGGGCGGGATGATCTTCCCGCCGGAAAGCTAC
TGGCCGGAAATCCAGCGCATCTGCCGCCAATACGACGTGCTGCTGTGCGCCGATGAAGTGATCGGTGGCTTCGGTCGCAC
TGGCGAATGGTTCGCCCACGAATACTTCGGTTTCGAGCCGGACACCCTGTCCATCGCCAAGGGCTTGACCTCCGGTTACA
TCCCCATGGGCGGGCTGATCCTGTCGAAGAAAATGGCCGACGTGCTGGTGGAGCAGGGCGGTGTGTTCGCCCACGGTCTG
ACCTATTCCGGGCACCCGGTGGCGGCGGCGGTGGCGATTGCCAACCTCAAGGCGCTGCGCGATGAAGGCGTGGTGACGCG
GGTCAAGGATGACATCGGCCCGTACCTGCAACAGTGTCTGCGCGAGGTGTTCGGCAATCACCCGTTGGTGGGCGATATCC
AGGGCACGGGCATGGTCGCGGCGCTGCAACTGGCCGAAGACAAGGCCACGCGCAAGCGCTTTGCCAATGAGAACGACATC
GCCTGGCGCTGCCGCACGATCGGTTTTGAAGAGGGGGTGATCATTCGCTCGACACTGGGGCGGATGATCATGGCGCCGGC
GCTGATTGCCAGTCGTGAAGAGATTGACGAACTGGTGGGCAAGACGTTGAAAGCGCTGGATCGTACCGCGCAGGAATACG
GTCGGCTCTGA

Upstream 100 bases:

>100_bases
ATCTGTCGCTGCACTCGTTCGACAAATACACCCAGTTGAAAACCACCTGGTTTCAACTGCGCTCATGACAGCCGCTCACA
ACAAGAAAGGAGATCCGGCG

Downstream 100 bases:

>100_bases
TTTGAAACCTGTGTGAAACGCTAACAATCGCAGCCTTCGGCTGCGATTTTTTTGAGCTTTGCACCCACCTCGGGCACCCC
CGTCCGACACGCCCTTTCGC

Product: putative aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MTTSRETRDYQAADAAHHIHAFVDQKALNDEGPRVMVRGDRLHLWDNDGRRYLDGMSGLWCTNLGYGRKDLNAAASRQLE
QLPYYNMFFHTTHPQVIELSELLFSLLPGHYSHAIYTNSGSEANEVLIRTVRRYWQVLGKPEKKIMIGRWNGYHGSTLAA
TALGGMKFMHEMGGMIPDIAHIDEPYFFAHEGNLTPAEFGLRAAQQLEAKILELGADKVAGFIAEPFQGAGGMIFPPESY
WPEIQRICRQYDVLLCADEVIGGFGRTGEWFAHEYFGFEPDTLSIAKGLTSGYIPMGGLILSKKMADVLVEQGGVFAHGL
TYSGHPVAAAVAIANLKALRDEGVVTRVKDDIGPYLQQCLREVFGNHPLVGDIQGTGMVAALQLAEDKATRKRFANENDI
AWRCRTIGFEEGVIIRSTLGRMIMAPALIASREEIDELVGKTLKALDRTAQEYGRL

Sequences:

>Translated_456_residues
MTTSRETRDYQAADAAHHIHAFVDQKALNDEGPRVMVRGDRLHLWDNDGRRYLDGMSGLWCTNLGYGRKDLNAAASRQLE
QLPYYNMFFHTTHPQVIELSELLFSLLPGHYSHAIYTNSGSEANEVLIRTVRRYWQVLGKPEKKIMIGRWNGYHGSTLAA
TALGGMKFMHEMGGMIPDIAHIDEPYFFAHEGNLTPAEFGLRAAQQLEAKILELGADKVAGFIAEPFQGAGGMIFPPESY
WPEIQRICRQYDVLLCADEVIGGFGRTGEWFAHEYFGFEPDTLSIAKGLTSGYIPMGGLILSKKMADVLVEQGGVFAHGL
TYSGHPVAAAVAIANLKALRDEGVVTRVKDDIGPYLQQCLREVFGNHPLVGDIQGTGMVAALQLAEDKATRKRFANENDI
AWRCRTIGFEEGVIIRSTLGRMIMAPALIASREEIDELVGKTLKALDRTAQEYGRL
>Mature_455_residues
TTSRETRDYQAADAAHHIHAFVDQKALNDEGPRVMVRGDRLHLWDNDGRRYLDGMSGLWCTNLGYGRKDLNAAASRQLEQ
LPYYNMFFHTTHPQVIELSELLFSLLPGHYSHAIYTNSGSEANEVLIRTVRRYWQVLGKPEKKIMIGRWNGYHGSTLAAT
ALGGMKFMHEMGGMIPDIAHIDEPYFFAHEGNLTPAEFGLRAAQQLEAKILELGADKVAGFIAEPFQGAGGMIFPPESYW
PEIQRICRQYDVLLCADEVIGGFGRTGEWFAHEYFGFEPDTLSIAKGLTSGYIPMGGLILSKKMADVLVEQGGVFAHGLT
YSGHPVAAAVAIANLKALRDEGVVTRVKDDIGPYLQQCLREVFGNHPLVGDIQGTGMVAALQLAEDKATRKRFANENDIA
WRCRTIGFEEGVIIRSTLGRMIMAPALIASREEIDELVGKTLKALDRTAQEYGRL

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=434, Percent_Identity=28.110599078341, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI37574042, Length=366, Percent_Identity=28.4153005464481, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI226442705, Length=366, Percent_Identity=28.6885245901639, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI4557809, Length=418, Percent_Identity=26.555023923445, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI226442709, Length=335, Percent_Identity=28.3582089552239, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI24119277, Length=425, Percent_Identity=26.8235294117647, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI284507298, Length=333, Percent_Identity=27.027027027027, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI188536080, Length=291, Percent_Identity=26.4604810996564, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI38679950, Length=291, Percent_Identity=26.4604810996564, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI38679946, Length=291, Percent_Identity=26.4604810996564, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI145693181, Length=408, Percent_Identity=26.7156862745098, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1786991, Length=457, Percent_Identity=29.7592997811816, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788044, Length=410, Percent_Identity=27.5609756097561, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1789759, Length=408, Percent_Identity=27.4509803921569, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1789016, Length=380, Percent_Identity=28.1578947368421, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787560, Length=375, Percent_Identity=29.8666666666667, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=24.3589743589744, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71992977, Length=377, Percent_Identity=29.4429708222812, Blast_Score=148, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI25144271, Length=423, Percent_Identity=25.0591016548463, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32564660, Length=447, Percent_Identity=27.0693512304251, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI25144274, Length=281, Percent_Identity=27.4021352313167, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323470, Length=458, Percent_Identity=26.2008733624454, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324432, Length=425, Percent_Identity=27.0588235294118, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324386, Length=463, Percent_Identity=25.9179265658747, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21356575, Length=432, Percent_Identity=26.8518518518519, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI161085790, Length=439, Percent_Identity=28.9293849658314, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28574759, Length=411, Percent_Identity=28.7104622871046, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI21357415, Length=425, Percent_Identity=25.8823529411765, Blast_Score=125, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 50635; Mature: 50504

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSRETRDYQAADAAHHIHAFVDQKALNDEGPRVMVRGDRLHLWDNDGRRYLDGMSGLW
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCHHHHHCCCCCE
CTNLGYGRKDLNAAASRQLEQLPYYNMFFHTTHPQVIELSELLFSLLPGHYSHAIYTNSG
ECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCC
SEANEVLIRTVRRYWQVLGKPEKKIMIGRWNGYHGSTLAATALGGMKFMHEMGGMIPDIA
CHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHH
HIDEPYFFAHEGNLTPAEFGLRAAQQLEAKILELGADKVAGFIAEPFQGAGGMIFPPESY
HCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCEECCCHHC
WPEIQRICRQYDVLLCADEVIGGFGRTGEWFAHEYFGFEPDTLSIAKGLTSGYIPMGGLI
CHHHHHHHHHHHHHEEHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHH
LSKKMADVLVEQGGVFAHGLTYSGHPVAAAVAIANLKALRDEGVVTRVKDDIGPYLQQCL
HHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
REVFGNHPLVGDIQGTGMVAALQLAEDKATRKRFANENDIAWRCRTIGFEEGVIIRSTLG
HHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEHHHHHH
RMIMAPALIASREEIDELVGKTLKALDRTAQEYGRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTSRETRDYQAADAAHHIHAFVDQKALNDEGPRVMVRGDRLHLWDNDGRRYLDGMSGLW
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCHHHHHCCCCCE
CTNLGYGRKDLNAAASRQLEQLPYYNMFFHTTHPQVIELSELLFSLLPGHYSHAIYTNSG
ECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCC
SEANEVLIRTVRRYWQVLGKPEKKIMIGRWNGYHGSTLAATALGGMKFMHEMGGMIPDIA
CHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHH
HIDEPYFFAHEGNLTPAEFGLRAAQQLEAKILELGADKVAGFIAEPFQGAGGMIFPPESY
HCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCEECCCHHC
WPEIQRICRQYDVLLCADEVIGGFGRTGEWFAHEYFGFEPDTLSIAKGLTSGYIPMGGLI
CHHHHHHHHHHHHHEEHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHH
LSKKMADVLVEQGGVFAHGLTYSGHPVAAAVAIANLKALRDEGVVTRVKDDIGPYLQQCL
HHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
REVFGNHPLVGDIQGTGMVAALQLAEDKATRKRFANENDIAWRCRTIGFEEGVIIRSTLG
HHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEHHHHHH
RMIMAPALIASREEIDELVGKTLKALDRTAQEYGRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]