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The map label for this gene is ndh [H]

Identifier: 77461052

GI number: 77461052

Start: 5447336

End: 5448634

Strand: Direct

Name: ndh [H]

Synonym: Pfl01_4831

Alternate gene names: 77461052

Gene position: 5447336-5448634 (Clockwise)

Preceding gene: 77461051

Following gene: 77461053

Centisome position: 84.61

GC content: 62.74

Gene sequence:

>1299_bases
ATGTCCCATCGTATTGTCATTGTCGGCGGCGGCGCCGGCGGTCTGGAGTTGGCTACCCGTCTGGGTAAGACCCTGGGCAA
ACGCGGCACCGCCAGCATCATGCTGGTCGACGCGAACCTCACGCACATCTGGAAACCGCTGCTGCACGAAGTGGCCGCCG
GATCGCTGAACTCCTCCGAAGACGAACTCAACTATGTCGCCCAGGCCAAATGGAACCACTTCGAGTTTCAGCTGGGGCGC
ATGAGCGGGCTCGATCGTGAGCAGAAGAAGATCCAGCTGGCCGCCACCTACGACGAAAACGGCGTTGAGCTGGTGCCGGC
GCGAGAAGTGCCCTATGACTCGCTGGTGATCGCGGTCGGCAGCACCACCAACGACTTCGGCACCCAAGGCGCCGCGCAAC
ACTGCCTGTTCCTCGACACCCGCAAGCAGGCCGAGCGTTTCCACCAGCAACTGCTCAATCACTATCTGCGCGCTCACGCC
GGGCAGACCGATGCGGTCCAGCAGATCAGCGTGGCCATCGTCGGCGCCGGCGCCACGGGCGTCGAACTGGCGGCAGAACT
GCACAACGCCGCTCATGAGCTGGCCGCCTACGGTCTGGACCGGATCAAACCGGAAAACATGCACATCACCCTGATCGAAG
CCGGGCCACGGGTGCTGCCAGCACTGCCTGAACGTATCAGCGGGCCGGTGCACAAGACTCTGGAGAAACTCGGGGTCAAC
GTGATGACCAACGCTTCGGTCAGCCAGGTCACCGCTGACAGCCTGATCACCGCCGATGGCAACGAGATCAAGGCCAGCCT
GAAAGTCTGGGCCGCCGGGATCCGCGCGCCAGCGTTCCTCAAGGACATCGACGGGCTGGAAACCAACCGCATCAACCAGT
TGCAAGTGCTGCCGACGCTGCAAACCACCCGCGATGAAAATATTTTCGCCTTCGGTGACTGCGCCGCCTGCCCGCAACCG
GGCTCCGATCGCAACGTTCCACCACGGGCCCAGGCTGCGCACCAACAGGCGTCGCTGCTGGCCAAATCGCTGAAACTGCG
GATCGAAGGCAAAACCTTGCCGGAGTACAAGTACACCGACTACGGCTCGCTGATTTCGCTGTCGCGTTTTTCGGCTGTGG
GTAACTTGATGGGTAACCTGACCGGCAGCGTGATGCTCGAAGGCTGGCTGGCGCGGATGTTTTACGTGTCGCTGTACCGC
ATGCACCAGATGGCGCTGTACGGGCCGTTCCGCACGGCGATGCTGATGCTCGGCAGCAAGATCGGACGCGGCACCGAGCC
GCGCCTGAAGCTGCACTGA

Upstream 100 bases:

>100_bases
CCTGTTGAGCCGTTTAATCAGTTACCTGACGCTATGAGCTGCATCGCGCTCGCTCGGGTAGCTGCACCGATTTCCTTTCA
AAACCTTGCGAGCTATCCCT

Downstream 100 bases:

>100_bases
TGTAAAAACACCGTGGGGGCGGGCTCGCCCTCACGGTGTTTTGTTTTCTACTGTATCTGCCCCAGCTTTCCCCACCTTCG
CTTACAAACGCCCCGCTCCT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSHRIVIVGGGAGGLELATRLGKTLGKRGTASIMLVDANLTHIWKPLLHEVAAGSLNSSEDELNYVAQAKWNHFEFQLGR
MSGLDREQKKIQLAATYDENGVELVPAREVPYDSLVIAVGSTTNDFGTQGAAQHCLFLDTRKQAERFHQQLLNHYLRAHA
GQTDAVQQISVAIVGAGATGVELAAELHNAAHELAAYGLDRIKPENMHITLIEAGPRVLPALPERISGPVHKTLEKLGVN
VMTNASVSQVTADSLITADGNEIKASLKVWAAGIRAPAFLKDIDGLETNRINQLQVLPTLQTTRDENIFAFGDCAACPQP
GSDRNVPPRAQAAHQQASLLAKSLKLRIEGKTLPEYKYTDYGSLISLSRFSAVGNLMGNLTGSVMLEGWLARMFYVSLYR
MHQMALYGPFRTAMLMLGSKIGRGTEPRLKLH

Sequences:

>Translated_432_residues
MSHRIVIVGGGAGGLELATRLGKTLGKRGTASIMLVDANLTHIWKPLLHEVAAGSLNSSEDELNYVAQAKWNHFEFQLGR
MSGLDREQKKIQLAATYDENGVELVPAREVPYDSLVIAVGSTTNDFGTQGAAQHCLFLDTRKQAERFHQQLLNHYLRAHA
GQTDAVQQISVAIVGAGATGVELAAELHNAAHELAAYGLDRIKPENMHITLIEAGPRVLPALPERISGPVHKTLEKLGVN
VMTNASVSQVTADSLITADGNEIKASLKVWAAGIRAPAFLKDIDGLETNRINQLQVLPTLQTTRDENIFAFGDCAACPQP
GSDRNVPPRAQAAHQQASLLAKSLKLRIEGKTLPEYKYTDYGSLISLSRFSAVGNLMGNLTGSVMLEGWLARMFYVSLYR
MHQMALYGPFRTAMLMLGSKIGRGTEPRLKLH
>Mature_431_residues
SHRIVIVGGGAGGLELATRLGKTLGKRGTASIMLVDANLTHIWKPLLHEVAAGSLNSSEDELNYVAQAKWNHFEFQLGRM
SGLDREQKKIQLAATYDENGVELVPAREVPYDSLVIAVGSTTNDFGTQGAAQHCLFLDTRKQAERFHQQLLNHYLRAHAG
QTDAVQQISVAIVGAGATGVELAAELHNAAHELAAYGLDRIKPENMHITLIEAGPRVLPALPERISGPVHKTLEKLGVNV
MTNASVSQVTADSLITADGNEIKASLKVWAAGIRAPAFLKDIDGLETNRINQLQVLPTLQTTRDENIFAFGDCAACPQPG
SDRNVPPRAQAAHQQASLLAKSLKLRIEGKTLPEYKYTDYGSLISLSRFSAVGNLMGNLTGSVMLEGWLARMFYVSLYRM
HQMALYGPFRTAMLMLGSKIGRGTEPRLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=430, Percent_Identity=56.2790697674419, Blast_Score=469, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6323515, Length=447, Percent_Identity=25.0559284116331, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6323794, Length=362, Percent_Identity=25.6906077348066, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320118, Length=437, Percent_Identity=24.4851258581236, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 46973; Mature: 46841

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHRIVIVGGGAGGLELATRLGKTLGKRGTASIMLVDANLTHIWKPLLHEVAAGSLNSSE
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCH
DELNYVAQAKWNHFEFQLGRMSGLDREQKKIQLAATYDENGVELVPAREVPYDSLVIAVG
HHHHHHHHCCCCCEEEEEHHHCCCCCHHHEEEEEEEECCCCCEEEECCCCCCCEEEEEEC
STTNDFGTQGAAQHCLFLDTRKQAERFHQQLLNHYLRAHAGQTDAVQQISVAIVGAGATG
CCCCCCCCCCHHCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEEEEECCCCH
VELAAELHNAAHELAAYGLDRIKPENMHITLIEAGPRVLPALPERISGPVHKTLEKLGVN
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHCCHHHHHHHHHCCE
VMTNASVSQVTADSLITADGNEIKASLKVWAAGIRAPAFLKDIDGLETNRINQLQVLPTL
EEECCCHHHHHHHHEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEEECH
QTTRDENIFAFGDCAACPQPGSDRNVPPRAQAAHQQASLLAKSLKLRIEGKTLPEYKYTD
HCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCC
YGSLISLSRFSAVGNLMGNLTGSVMLEGWLARMFYVSLYRMHQMALYGPFRTAMLMLGSK
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRGTEPRLKLH
CCCCCCCCEECC
>Mature Secondary Structure 
SHRIVIVGGGAGGLELATRLGKTLGKRGTASIMLVDANLTHIWKPLLHEVAAGSLNSSE
CCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCH
DELNYVAQAKWNHFEFQLGRMSGLDREQKKIQLAATYDENGVELVPAREVPYDSLVIAVG
HHHHHHHHCCCCCEEEEEHHHCCCCCHHHEEEEEEEECCCCCEEEECCCCCCCEEEEEEC
STTNDFGTQGAAQHCLFLDTRKQAERFHQQLLNHYLRAHAGQTDAVQQISVAIVGAGATG
CCCCCCCCCCHHCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEEEEECCCCH
VELAAELHNAAHELAAYGLDRIKPENMHITLIEAGPRVLPALPERISGPVHKTLEKLGVN
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHCCHHHHHHHHHCCE
VMTNASVSQVTADSLITADGNEIKASLKVWAAGIRAPAFLKDIDGLETNRINQLQVLPTL
EEECCCHHHHHHHHEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEEECH
QTTRDENIFAFGDCAACPQPGSDRNVPPRAQAAHQQASLLAKSLKLRIEGKTLPEYKYTD
HCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCC
YGSLISLSRFSAVGNLMGNLTGSVMLEGWLARMFYVSLYRMHQMALYGPFRTAMLMLGSK
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRGTEPRLKLH
CCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]