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The map label for this gene is bdlA [H]

Identifier: 77460987

GI number: 77460987

Start: 5371920

End: 5373236

Strand: Reverse

Name: bdlA [H]

Synonym: Pfl01_4766

Alternate gene names: 77460987

Gene position: 5373236-5371920 (Counterclockwise)

Preceding gene: 77460988

Following gene: 77460986

Centisome position: 83.46

GC content: 61.35

Gene sequence:

>1317_bases
ATGTTCAACAAACGCCTGAAGCAAGAGCTGGCGGCTCTTCGTGAAGAACTCTCCAGCCTTCTGCAAGTGAAGGAGAGCCT
GGAAAGCGAGATGCTGGTGCTCACCCTTGAGCCCGACGGACGGATTCAGTCGGTCAACCAGAACTTCCTCAGCGAAATGC
TCTACAAGAGCCACGACCTGATTGGCCGCGCCATCGAAGACATCGTGCCGGCCCATGTGAAATCCGACGAATTTCATCAC
CGCTTCAAGGCCGCTCTGACCCGTGGCGAGCATTTTGCCGGCGCCGTTCGCCTTTCCCGCGGCAATGGCGAAGAGGCGTG
GCTGCGTTCGATCGTGCAGCCGATTCGCTCGTCGGATGGCCGGATCAAGCACTTCTCGATTTTCTCCAGCGACCTGACCC
GCACCATCGAGGCCTCGCGCGAACACGAAAACCTGATCGGCGCACTGGTGCGTTCGACCGCCGTGATCGAGTTCGACCTC
AGCGGCAACGTACTGAGTGCCAACGACCGGTTCCTGCAGGGCATGGGTTACAGCCTGGCGCAGATCAAGGGCAAACATCA
CCGCCAGTTCTGCGAGCCGGAGGAGTACAACAGCGCCGAGTACCAGAACTTCTGGCGTCGCCTGAATAACGGCGAATTCG
TTGCCGGCCGTTTTAAGCGAGTCGATAGCCATGGTCGGACGGTCTGGCTGGAGGCGTCCTACAACCCGGTGCTCGACGCC
AACGAAAAGCTCTACAAAGTGGTGAAGTTCGCCACGGTGATCACCGATCAGGTCAATCAAGAGCAGGCCGTCGCCGATGC
CGCCAATATCGCCTACAGCACGTCCCTGCAAACCGACAGCACCGCCCAGCGTGGCACCCGTGTGGTGACCGAAGCGGTCA
ATGTGATGCGCGATCTGTCGAAGCACATGCAGACCGCCGGCGAAGGCATCGAGGCGCTGAACGAGCAATCCCAGGTGATC
GGCACCATCGTCAAGACCATCAGCGGCATTGCCGAACAGACCAACCTGCTGGCACTTAACGCCGCCATCGAAGCCGCTCG
CGCCGGTGAACAGGGGCGCGGGTTTGCGGTGGTGGCCGACGAAGTGCGGCAACTGGCTTCGCGCACCAGCCAGGCGACCG
AGGAAATCGTCGGCGTGGTTCGCCAGAACCAGGACATGGCGCGCAACGCCGTGGCCCTGATGACCGACGGCAAGCAACAG
GCCGAGCAAGGTCTGGCGCTGGCGGCGGAGGCCGGTACGGTGATCGTCGAGATCCAGGACGGCGCGCAGAAAGTGGTGGA
TGCAGTCGGCCAGTTCGCCAACCAGCTATCCAACTGA

Upstream 100 bases:

>100_bases
ATTTTTGTAGGACAAGCCTCGCGCGCTCTTCAGAAAAGATTTCCAAGGCCGATGGCTAGGCTGCATACCCGCTATCCATC
CAGTCCATCGGTGCTTTCCC

Downstream 100 bases:

>100_bases
TGCCTGCCAGGCGAAGGGATTGCCCACGGCAATCCCTTCGTTGTTTTTATCCCGCTACAATCGGCTCTTTTTCCCGGAGC
AGATCCCATGAGCGAGTCCT

Product: Pas/Pac sensor-containing chemotaxis sensory transducer

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MFNKRLKQELAALREELSSLLQVKESLESEMLVLTLEPDGRIQSVNQNFLSEMLYKSHDLIGRAIEDIVPAHVKSDEFHH
RFKAALTRGEHFAGAVRLSRGNGEEAWLRSIVQPIRSSDGRIKHFSIFSSDLTRTIEASREHENLIGALVRSTAVIEFDL
SGNVLSANDRFLQGMGYSLAQIKGKHHRQFCEPEEYNSAEYQNFWRRLNNGEFVAGRFKRVDSHGRTVWLEASYNPVLDA
NEKLYKVVKFATVITDQVNQEQAVADAANIAYSTSLQTDSTAQRGTRVVTEAVNVMRDLSKHMQTAGEGIEALNEQSQVI
GTIVKTISGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLASRTSQATEEIVGVVRQNQDMARNAVALMTDGKQQ
AEQGLALAAEAGTVIVEIQDGAQKVVDAVGQFANQLSN

Sequences:

>Translated_438_residues
MFNKRLKQELAALREELSSLLQVKESLESEMLVLTLEPDGRIQSVNQNFLSEMLYKSHDLIGRAIEDIVPAHVKSDEFHH
RFKAALTRGEHFAGAVRLSRGNGEEAWLRSIVQPIRSSDGRIKHFSIFSSDLTRTIEASREHENLIGALVRSTAVIEFDL
SGNVLSANDRFLQGMGYSLAQIKGKHHRQFCEPEEYNSAEYQNFWRRLNNGEFVAGRFKRVDSHGRTVWLEASYNPVLDA
NEKLYKVVKFATVITDQVNQEQAVADAANIAYSTSLQTDSTAQRGTRVVTEAVNVMRDLSKHMQTAGEGIEALNEQSQVI
GTIVKTISGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLASRTSQATEEIVGVVRQNQDMARNAVALMTDGKQQ
AEQGLALAAEAGTVIVEIQDGAQKVVDAVGQFANQLSN
>Mature_438_residues
MFNKRLKQELAALREELSSLLQVKESLESEMLVLTLEPDGRIQSVNQNFLSEMLYKSHDLIGRAIEDIVPAHVKSDEFHH
RFKAALTRGEHFAGAVRLSRGNGEEAWLRSIVQPIRSSDGRIKHFSIFSSDLTRTIEASREHENLIGALVRSTAVIEFDL
SGNVLSANDRFLQGMGYSLAQIKGKHHRQFCEPEEYNSAEYQNFWRRLNNGEFVAGRFKRVDSHGRTVWLEASYNPVLDA
NEKLYKVVKFATVITDQVNQEQAVADAANIAYSTSLQTDSTAQRGTRVVTEAVNVMRDLSKHMQTAGEGIEALNEQSQVI
GTIVKTISGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRQLASRTSQATEEIVGVVRQNQDMARNAVALMTDGKQQ
AEQGLALAAEAGTVIVEIQDGAQKVVDAVGQFANQLSN

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=170, Percent_Identity=41.7647058823529, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788195, Length=170, Percent_Identity=39.4117647058824, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788194, Length=123, Percent_Identity=49.5934959349593, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789453, Length=127, Percent_Identity=43.3070866141732, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787690, Length=72, Percent_Identity=61.1111111111111, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 48336; Mature: 48336

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNKRLKQELAALREELSSLLQVKESLESEMLVLTLEPDGRIQSVNQNFLSEMLYKSHDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
IGRAIEDIVPAHVKSDEFHHRFKAALTRGEHFAGAVRLSRGNGEEAWLRSIVQPIRSSDG
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHCEEEEECCCCHHHHHHHHHHHHHCCCC
RIKHFSIFSSDLTRTIEASREHENLIGALVRSTAVIEFDLSGNVLSANDRFLQGMGYSLA
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEECCCHHHHHHCCCHHH
QIKGKHHRQFCEPEEYNSAEYQNFWRRLNNGEFVAGRFKRVDSHGRTVWLEASYNPVLDA
HHCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHCCCCCEEEEEECCCCCCCC
NEKLYKVVKFATVITDQVNQEQAVADAANIAYSTSLQTDSTAQRGTRVVTEAVNVMRDLS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHH
KHMQTAGEGIEALNEQSQVIGTIVKTISGIAEQTNLLALNAAIEAARAGEQGRGFAVVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCEEEHHH
EVRQLASRTSQATEEIVGVVRQNQDMARNAVALMTDGKQQAEQGLALAAEAGTVIVEIQD
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCHHHHHCCCEEEECCCEEEEEECC
GAQKVVDAVGQFANQLSN
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFNKRLKQELAALREELSSLLQVKESLESEMLVLTLEPDGRIQSVNQNFLSEMLYKSHDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
IGRAIEDIVPAHVKSDEFHHRFKAALTRGEHFAGAVRLSRGNGEEAWLRSIVQPIRSSDG
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHCEEEEECCCCHHHHHHHHHHHHHCCCC
RIKHFSIFSSDLTRTIEASREHENLIGALVRSTAVIEFDLSGNVLSANDRFLQGMGYSLA
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEECCCHHHHHHCCCHHH
QIKGKHHRQFCEPEEYNSAEYQNFWRRLNNGEFVAGRFKRVDSHGRTVWLEASYNPVLDA
HHCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHCCCCCEEEEEECCCCCCCC
NEKLYKVVKFATVITDQVNQEQAVADAANIAYSTSLQTDSTAQRGTRVVTEAVNVMRDLS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHH
KHMQTAGEGIEALNEQSQVIGTIVKTISGIAEQTNLLALNAAIEAARAGEQGRGFAVVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCEEEHHH
EVRQLASRTSQATEEIVGVVRQNQDMARNAVALMTDGKQQAEQGLALAAEAGTVIVEIQD
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCHHHHHCCCEEEECCCEEEEEECC
GAQKVVDAVGQFANQLSN
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]