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The map label for this gene is norR [H]

Identifier: 77460874

GI number: 77460874

Start: 5250744

End: 5252297

Strand: Direct

Name: norR [H]

Synonym: Pfl01_4653

Alternate gene names: 77460874

Gene position: 5250744-5252297 (Clockwise)

Preceding gene: 77460870

Following gene: 77460875

Centisome position: 81.55

GC content: 64.86

Gene sequence:

>1554_bases
ATGTCCGCCAAATCATTGCTCACCGCCCTGCTCCCACTGGTCTCCGACCTGTCCCGCGAATTGCCCGAAGGCGAGCGCTA
CCGACGCCTGCTCGAAGCCATGCGCGCCCTGCTGCCCTGCGATGCCGCCGCATTGTTGCGCCTCGACGGTGAATGGCTGG
TGCCGCTGGCCGTGGACGGCTTGAGTACCGACACCCTCGGCCGCCGTTTCAAGGTCAGCGAACACCCGCGCTTTGAAGTG
CTGTTGGCCGGCGAAGGGCCGACCCGTTTCGCCGCCGACAGCGATCTGCCCGATCCGTACGACGGACTGGTCGACGGCCT
CGACGATCATCTTGAAGTTCACGATTGCCTCGGCTGTCCGTTGTTCGTCGATGAAAAGCTGTGGGGGCTGATCACCCTCG
ACGCCCTCGATCCGGAGCGCTTCGAACCGATCGAACTCGACGCCCTGCAAGCCTTCGCCAGCCTCGCTTCGGCCACGGTC
AACGCCGCCGAACGCATCGAGCGTCTGGCGACCCGCGCCGAAGACGAACACCAGCGCGCCGAGGTCTATCGCCAGGCCAG
CGGTCAGCAGAATCGCGAAATGATCGGCCAGAGCAAAGCGCATAAACGGCTGGTCGAAGAAATCAATCTGGTGGGCGGCA
GCGACCTGACCGTGCTGATCACCGGCGAAACCGGGGTCGGCAAGGAACTGGTGGCCCAGGCGATCCACGCCGCCTCCAAG
CGCGCCGACAAACCGATCATCAGCCTCAACTGCGCGGCCCTGCCGGACACGCTGGTGGAAAGCGAACTGTTCGGCCACGT
GCGCGGCGCCTTCACCGGCGCCACCAGCGACCGGCGCGGCAAGTTCGAACTGGCCAACGGCGGCACGCTTTTTCTCGATG
AAGTCGGCGAGTTGTCGCTGACCGTCCAGGCCAAACTGTTGCGGGTTTTGCAGAGCGGCCAGTTGCAGCGTCTGGGTTCG
GACAAGGAGCATCAGGTCGACGTGCGCCTGATCGCCGCGACCAACCGCGACCTGGCCGAAGAAGTGCGCAGCGGCCGCTA
CCGCGCCGACTTCTACCATCGCCTCAGCGTCTACCCATTGCGAGTGCCGGCGCTGCGTGACCGGGGGCGCGATGTGTTGT
TGCTCAGCGGCTATTTCCTGGAACAGAACCGCTCGCGCATGGGCCTCAACAGCCTGCGCCTGAACAGCGATGCCCAGGAG
GCGCTGCTGACCTACACCTGGCCAGGCAACGTGCGGGAACTGGAGCACTTGATCGGACGCAGCGCGCTGAAGGCGCTGGG
CAACTGCAAGGTGCGACCGAAGATTCTCAGCCTGAGCGCGATGGACCTCGATCTGCCGCGCGAGGTTGTGGATAACTCGC
CGATGCCGTCCGAAGCGACTGCCGCTCTGCCCTTGATCAGCGGCGATCTGCGCACCGCCACCGAGCAGTATCAGCGGCAG
TTGATCAGTGCAGCGCTTGAGCGCAATCAGGACAACTGGGCCAGTGCCGCCCGTGAACTGGGGCTGGACCGGGCGAATCT
GGGGCGGATGGCCAAGCGCTTGGGGATGAAATAA

Upstream 100 bases:

>100_bases
TTTTCTATATAAATCAATAGCTTGAAAATTATGTAGTCAGATCGACACAAGCACCTCTATAGTCGCTTCGACTACAACAT
GTCTCTTTGACTACAAGCCT

Downstream 100 bases:

>100_bases
AAGTCCCGCCGTCGGATTGGCGCCAGAATCCCTAAAGCCTGCCGGTTACAAGTCGATAACCCGGCATCGATACCTGCTGG
CGATCCGTGCGATCGCCGCT

Product: anaerobic nitric oxide reductase transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MSAKSLLTALLPLVSDLSRELPEGERYRRLLEAMRALLPCDAAALLRLDGEWLVPLAVDGLSTDTLGRRFKVSEHPRFEV
LLAGEGPTRFAADSDLPDPYDGLVDGLDDHLEVHDCLGCPLFVDEKLWGLITLDALDPERFEPIELDALQAFASLASATV
NAAERIERLATRAEDEHQRAEVYRQASGQQNREMIGQSKAHKRLVEEINLVGGSDLTVLITGETGVGKELVAQAIHAASK
RADKPIISLNCAALPDTLVESELFGHVRGAFTGATSDRRGKFELANGGTLFLDEVGELSLTVQAKLLRVLQSGQLQRLGS
DKEHQVDVRLIAATNRDLAEEVRSGRYRADFYHRLSVYPLRVPALRDRGRDVLLLSGYFLEQNRSRMGLNSLRLNSDAQE
ALLTYTWPGNVRELEHLIGRSALKALGNCKVRPKILSLSAMDLDLPREVVDNSPMPSEATAALPLISGDLRTATEQYQRQ
LISAALERNQDNWASAARELGLDRANLGRMAKRLGMK

Sequences:

>Translated_517_residues
MSAKSLLTALLPLVSDLSRELPEGERYRRLLEAMRALLPCDAAALLRLDGEWLVPLAVDGLSTDTLGRRFKVSEHPRFEV
LLAGEGPTRFAADSDLPDPYDGLVDGLDDHLEVHDCLGCPLFVDEKLWGLITLDALDPERFEPIELDALQAFASLASATV
NAAERIERLATRAEDEHQRAEVYRQASGQQNREMIGQSKAHKRLVEEINLVGGSDLTVLITGETGVGKELVAQAIHAASK
RADKPIISLNCAALPDTLVESELFGHVRGAFTGATSDRRGKFELANGGTLFLDEVGELSLTVQAKLLRVLQSGQLQRLGS
DKEHQVDVRLIAATNRDLAEEVRSGRYRADFYHRLSVYPLRVPALRDRGRDVLLLSGYFLEQNRSRMGLNSLRLNSDAQE
ALLTYTWPGNVRELEHLIGRSALKALGNCKVRPKILSLSAMDLDLPREVVDNSPMPSEATAALPLISGDLRTATEQYQRQ
LISAALERNQDNWASAARELGLDRANLGRMAKRLGMK
>Mature_516_residues
SAKSLLTALLPLVSDLSRELPEGERYRRLLEAMRALLPCDAAALLRLDGEWLVPLAVDGLSTDTLGRRFKVSEHPRFEVL
LAGEGPTRFAADSDLPDPYDGLVDGLDDHLEVHDCLGCPLFVDEKLWGLITLDALDPERFEPIELDALQAFASLASATVN
AAERIERLATRAEDEHQRAEVYRQASGQQNREMIGQSKAHKRLVEEINLVGGSDLTVLITGETGVGKELVAQAIHAASKR
ADKPIISLNCAALPDTLVESELFGHVRGAFTGATSDRRGKFELANGGTLFLDEVGELSLTVQAKLLRVLQSGQLQRLGSD
KEHQVDVRLIAATNRDLAEEVRSGRYRADFYHRLSVYPLRVPALRDRGRDVLLLSGYFLEQNRSRMGLNSLRLNSDAQEA
LLTYTWPGNVRELEHLIGRSALKALGNCKVRPKILSLSAMDLDLPREVVDNSPMPSEATAALPLISGDLRTATEQYQRQL
ISAALERNQDNWASAARELGLDRANLGRMAKRLGMK

Specific function: Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54 [H]

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082152, Length=502, Percent_Identity=50.597609561753, Blast_Score=466, Evalue=1e-132,
Organism=Escherichia coli, GI1790437, Length=317, Percent_Identity=44.794952681388, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI1789087, Length=407, Percent_Identity=40.04914004914, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI87082117, Length=236, Percent_Identity=50.4237288135593, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI1788550, Length=331, Percent_Identity=39.2749244712991, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1790299, Length=368, Percent_Identity=39.1304347826087, Blast_Score=231, Evalue=7e-62,
Organism=Escherichia coli, GI1788905, Length=329, Percent_Identity=39.5136778115502, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1789233, Length=457, Percent_Identity=31.9474835886214, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI87081872, Length=321, Percent_Identity=38.006230529595, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1787583, Length=326, Percent_Identity=37.1165644171779, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI1786524, Length=334, Percent_Identity=38.0239520958084, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI1789828, Length=234, Percent_Identity=38.4615384615385, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI87081858, Length=231, Percent_Identity=34.6320346320346, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002078 [H]

Pfam domain/function: PF01590 GAF; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 57000; Mature: 56868

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKSLLTALLPLVSDLSRELPEGERYRRLLEAMRALLPCDAAALLRLDGEWLVPLAVDG
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHEEECCCEEEEEEECC
LSTDTLGRRFKVSEHPRFEVLLAGEGPTRFAADSDLPDPYDGLVDGLDDHLEVHDCLGCP
CCCHHCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCC
LFVDEKLWGLITLDALDPERFEPIELDALQAFASLASATVNAAERIERLATRAEDEHQRA
EEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
EVYRQASGQQNREMIGQSKAHKRLVEEINLVGGSDLTVLITGETGVGKELVAQAIHAASK
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
RADKPIISLNCAALPDTLVESELFGHVRGAFTGATSDRRGKFELANGGTLFLDEVGELSL
HCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEECCCCEEE
TVQAKLLRVLQSGQLQRLGSDKEHQVDVRLIAATNRDLAEEVRSGRYRADFYHRLSVYPL
HHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEEECCHHHHHHHHCCCEEHHHHHHHEEEEE
RVPALRDRGRDVLLLSGYFLEQNRSRMGLNSLRLNSDAQEALLTYTWPGNVRELEHLIGR
ECCHHHCCCCEEEEEECCHHHCCCCCCCCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHH
SALKALGNCKVRPKILSLSAMDLDLPREVVDNSPMPSEATAALPLISGDLRTATEQYQRQ
HHHHHHHCCCCCCEEEEEEECCCCCCHHHHCCCCCCCCHHHCCCEECCHHHHHHHHHHHH
LISAALERNQDNWASAARELGLDRANLGRMAKRLGMK
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAKSLLTALLPLVSDLSRELPEGERYRRLLEAMRALLPCDAAALLRLDGEWLVPLAVDG
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHEEECCCEEEEEEECC
LSTDTLGRRFKVSEHPRFEVLLAGEGPTRFAADSDLPDPYDGLVDGLDDHLEVHDCLGCP
CCCHHCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCC
LFVDEKLWGLITLDALDPERFEPIELDALQAFASLASATVNAAERIERLATRAEDEHQRA
EEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
EVYRQASGQQNREMIGQSKAHKRLVEEINLVGGSDLTVLITGETGVGKELVAQAIHAASK
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
RADKPIISLNCAALPDTLVESELFGHVRGAFTGATSDRRGKFELANGGTLFLDEVGELSL
HCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEECCCCEEE
TVQAKLLRVLQSGQLQRLGSDKEHQVDVRLIAATNRDLAEEVRSGRYRADFYHRLSVYPL
HHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEEECCHHHHHHHHCCCEEHHHHHHHEEEEE
RVPALRDRGRDVLLLSGYFLEQNRSRMGLNSLRLNSDAQEALLTYTWPGNVRELEHLIGR
ECCHHHCCCCEEEEEECCHHHCCCCCCCCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHH
SALKALGNCKVRPKILSLSAMDLDLPREVVDNSPMPSEATAALPLISGDLRTATEQYQRQ
HHHHHHHCCCCCCEEEEEEECCCCCCHHHHCCCCCCCCHHHCCCEECCHHHHHHHHHHHH
LISAALERNQDNWASAARELGLDRANLGRMAKRLGMK
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA