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The map label for this gene is cyoB [H]

Identifier: 77460868

GI number: 77460868

Start: 5244339

End: 5246369

Strand: Reverse

Name: cyoB [H]

Synonym: Pfl01_4647

Alternate gene names: 77460868

Gene position: 5246369-5244339 (Counterclockwise)

Preceding gene: 77460869

Following gene: 77460867

Centisome position: 81.49

GC content: 57.66

Gene sequence:

>2031_bases
ATGTTTGGTAAATTAAGTTGGGAAGCGATCCCTTTCCACGAGCCGATCGTGATGGTCACCATCTCGATGATCGCGCTCGG
TGGTCTGGCGTTGTTCGCTGCAATCACCTACTTCAAGAAGTGGACTTACCTGTGGACCGAGTGGCTGACGTCGGTCGACC
ACAAGAAAATCGGCGTGATGTACATCATCGTCGCCATGGTCATGCTGCTGCGCGGTTTTGCCGACGCCATCATGATGCGT
ACCCAGCTGGCCATGGCCACCGAGGGTTCGCCTGGCTATCTGCCACCTGAACACTATGACCAGATCTTCACCGCTCACGG
TGTGATCATGATCATCTTCATGGCGATGCCATTCTTCACCGGCCTGATGAACCTTGCAGTGCCGCTGCAGATCGGCGCAC
GTGACGTTGCGTTCCCGTTCCTGAACTCCCTGAGCTTCTGGCTGCTGGTGTCCGGCGTCGTGCTGATCAACCTGTCCCTG
GGCGTCGGCGAATTCGCCAAGACCGGCTGGGTTGCCTATCCACCGCTGTCGGGTCTGCAATACAGCCCTGGCGTGGGGAT
GGACTACTACATCTGGGCGCTACAGCTATCGGGTCTGGGTACAACGTTAACCGGGGTCAACTTCCTCGCGACCGTGCTGA
AAATGCGTACCCCTGGCATGAAACTGATGGACATGCCGATCTTCACCTGGACCTGCACCTGGGCAAACGTTCTGATCGTG
GCTTCGTTCCCGATCCTGACCGCTACCCTGGCACTGCTGACCCTTGACCGTTACATGGATTTCCACATTTTCACCAATGA
ACTTGGTGGCAATCCAATGATGTACGTCAACCTGTTCTGGGCATGGGGCCACCCTGAGGTTTACATCCTGATCCTGCCGG
CATTCGGCATTTTCTCGGAAGTCATCTCGGCCTTCACCGGCAAGAAACTGTTCGGCCACCACTCGATGATCTACGCCTCG
GGCGCGATCTCGGTACTGGGCTTCATGGTTTGGCTGCACCACTTCTTCACCATGGGTTCGGGTGCCAGCGTCAACGCCTT
CTTCGGTCTGGCGACGATGCTGATTTCCATCCCGACGGGTGTGAAACTGTTCAACTGGCTGTTCACCATCTACCAGGGCC
GTCTGCGCTTCACCAGCCAGGTTCTGTGGACCCTGGGCTTCATGGTGACCTTCGCCATCGGCGGCATGACCGGCGTACTG
CTGGCCATCCCGGGTGCTGACTTCGTTCTGCACAACAGCCTGTTCGTGATCGCTCACTTCCACAACGTGATCATCGGCGG
CGCGGTATTCGGCTACATCGCAGGTTTCGGCTTCTACTTCCCGAAAGCGTTCGGCTTCAAGCTGCACGAAGGCTGGGGTA
AAGCAGCGTTCTGGTTCTGGATCTCGGGCTTCTTCGTCGCGTTCATGCCGCTCTACGCTCTGGGCTTCATGGGCATGACC
CGTCGTCTGAACGCCACCACCAACCCTGAATGGGTACCGTACCTGTACGTTGCCATGTTCGGTGCGGTGATGATCGCTGT
GGGTATCGCCTGCCAGCTGATCCAGCTGTACGTGTCGGTGCGTGACCGCAACAAGCCGGAAAACATGTGCGAACACGGTG
ACCCGTGGAATGCCCATACCCTGGAATGGTCGACCTCGTCGCCACCTCCGTTCTACAACTTCGCTGTACTGCCAAAAGCA
GACTGCATCGATCCGTTCACCGAGGCCAAGGAAAACGGTACCGCGTACAAGGCACCAGCCAAGTACGAACCGATCCACAT
GCCGAACAACACCGCCACTGGCGTGGTGATGGGCGCACTGCTGACCGTGTTCGGTTTCGCGATGATCTGGCACATCTGGT
GGTTGGCGATCGCCAGCCTGGCCGGCACTGTCATCTACTTCGTGATCCACGCAGCACGTGACGATCAGGGCTACATGGTG
CCGGTTGAAACAATCGAGCGCATCGAAGCCGAGCAGCACAAGCGTCTGGTAGCGGCCGGGAAGATCCCTGCTTCCGCAAC
CCGTGTTGAAACCAAGTTGGAACAGGCTTAA

Upstream 100 bases:

>100_bases
ACCAGGCAAGCCGCTGAAGCACGAGAAGAAAGAGAAAGAAGTGGCGGCAACGGATATGGACTCGAATTCGCATTCAGCTG
CCGGGGCAGAGGAGTAAACG

Downstream 100 bases:

>100_bases
ACAATGTCGAACTTAGTGACCAATGCTGGACACGCCCATGGTCATGACCATGGGCACGATGACCATCACCACGACTCGGG
CGAGATGACCGTATACGGTT

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MFGKLSWEAIPFHEPIVMVTISMIALGGLALFAAITYFKKWTYLWTEWLTSVDHKKIGVMYIIVAMVMLLRGFADAIMMR
TQLAMATEGSPGYLPPEHYDQIFTAHGVIMIIFMAMPFFTGLMNLAVPLQIGARDVAFPFLNSLSFWLLVSGVVLINLSL
GVGEFAKTGWVAYPPLSGLQYSPGVGMDYYIWALQLSGLGTTLTGVNFLATVLKMRTPGMKLMDMPIFTWTCTWANVLIV
ASFPILTATLALLTLDRYMDFHIFTNELGGNPMMYVNLFWAWGHPEVYILILPAFGIFSEVISAFTGKKLFGHHSMIYAS
GAISVLGFMVWLHHFFTMGSGASVNAFFGLATMLISIPTGVKLFNWLFTIYQGRLRFTSQVLWTLGFMVTFAIGGMTGVL
LAIPGADFVLHNSLFVIAHFHNVIIGGAVFGYIAGFGFYFPKAFGFKLHEGWGKAAFWFWISGFFVAFMPLYALGFMGMT
RRLNATTNPEWVPYLYVAMFGAVMIAVGIACQLIQLYVSVRDRNKPENMCEHGDPWNAHTLEWSTSSPPPFYNFAVLPKA
DCIDPFTEAKENGTAYKAPAKYEPIHMPNNTATGVVMGALLTVFGFAMIWHIWWLAIASLAGTVIYFVIHAARDDQGYMV
PVETIERIEAEQHKRLVAAGKIPASATRVETKLEQA

Sequences:

>Translated_676_residues
MFGKLSWEAIPFHEPIVMVTISMIALGGLALFAAITYFKKWTYLWTEWLTSVDHKKIGVMYIIVAMVMLLRGFADAIMMR
TQLAMATEGSPGYLPPEHYDQIFTAHGVIMIIFMAMPFFTGLMNLAVPLQIGARDVAFPFLNSLSFWLLVSGVVLINLSL
GVGEFAKTGWVAYPPLSGLQYSPGVGMDYYIWALQLSGLGTTLTGVNFLATVLKMRTPGMKLMDMPIFTWTCTWANVLIV
ASFPILTATLALLTLDRYMDFHIFTNELGGNPMMYVNLFWAWGHPEVYILILPAFGIFSEVISAFTGKKLFGHHSMIYAS
GAISVLGFMVWLHHFFTMGSGASVNAFFGLATMLISIPTGVKLFNWLFTIYQGRLRFTSQVLWTLGFMVTFAIGGMTGVL
LAIPGADFVLHNSLFVIAHFHNVIIGGAVFGYIAGFGFYFPKAFGFKLHEGWGKAAFWFWISGFFVAFMPLYALGFMGMT
RRLNATTNPEWVPYLYVAMFGAVMIAVGIACQLIQLYVSVRDRNKPENMCEHGDPWNAHTLEWSTSSPPPFYNFAVLPKA
DCIDPFTEAKENGTAYKAPAKYEPIHMPNNTATGVVMGALLTVFGFAMIWHIWWLAIASLAGTVIYFVIHAARDDQGYMV
PVETIERIEAEQHKRLVAAGKIPASATRVETKLEQA
>Mature_676_residues
MFGKLSWEAIPFHEPIVMVTISMIALGGLALFAAITYFKKWTYLWTEWLTSVDHKKIGVMYIIVAMVMLLRGFADAIMMR
TQLAMATEGSPGYLPPEHYDQIFTAHGVIMIIFMAMPFFTGLMNLAVPLQIGARDVAFPFLNSLSFWLLVSGVVLINLSL
GVGEFAKTGWVAYPPLSGLQYSPGVGMDYYIWALQLSGLGTTLTGVNFLATVLKMRTPGMKLMDMPIFTWTCTWANVLIV
ASFPILTATLALLTLDRYMDFHIFTNELGGNPMMYVNLFWAWGHPEVYILILPAFGIFSEVISAFTGKKLFGHHSMIYAS
GAISVLGFMVWLHHFFTMGSGASVNAFFGLATMLISIPTGVKLFNWLFTIYQGRLRFTSQVLWTLGFMVTFAIGGMTGVL
LAIPGADFVLHNSLFVIAHFHNVIIGGAVFGYIAGFGFYFPKAFGFKLHEGWGKAAFWFWISGFFVAFMPLYALGFMGMT
RRLNATTNPEWVPYLYVAMFGAVMIAVGIACQLIQLYVSVRDRNKPENMCEHGDPWNAHTLEWSTSSPPPFYNFAVLPKA
DCIDPFTEAKENGTAYKAPAKYEPIHMPNNTATGVVMGALLTVFGFAMIWHIWWLAIASLAGTVIYFVIHAARDDQGYMV
PVETIERIEAEQHKRLVAAGKIPASATRVETKLEQA

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=512, Percent_Identity=37.890625, Blast_Score=317, Evalue=3e-86,
Organism=Escherichia coli, GI1786634, Length=660, Percent_Identity=68.1818181818182, Blast_Score=948, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=530, Percent_Identity=36.4150943396226, Blast_Score=322, Evalue=8e-89,
Organism=Saccharomyces cerevisiae, GI6226524, Length=326, Percent_Identity=41.7177914110429, Blast_Score=240, Evalue=4e-64,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=35.2226720647773, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 75205; Mature: 75205

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGKLSWEAIPFHEPIVMVTISMIALGGLALFAAITYFKKWTYLWTEWLTSVDHKKIGVM
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YIIVAMVMLLRGFADAIMMRTQLAMATEGSPGYLPPEHYDQIFTAHGVIMIIFMAMPFFT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLMNLAVPLQIGARDVAFPFLNSLSFWLLVSGVVLINLSLGVGEFAKTGWVAYPPLSGLQ
HHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHCCCEECCCCCCCC
YSPGVGMDYYIWALQLSGLGTTLTGVNFLATVLKMRTPGMKLMDMPIFTWTCTWANVLIV
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCEEEEEHHHHHHHHH
ASFPILTATLALLTLDRYMDFHIFTNELGGNPMMYVNLFWAWGHPEVYILILPAFGIFSE
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEEEEEEEECCCCEEEEEECHHHHHHH
VISAFTGKKLFGHHSMIYASGAISVLGFMVWLHHFFTMGSGASVNAFFGLATMLISIPTG
HHHHHCCCHHHCCCHHEEECHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCH
VKLFNWLFTIYQGRLRFTSQVLWTLGFMVTFAIGGMTGVLLAIPGADFVLHNSLFVIAHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEEECCCCEEHHCCEEEEEHH
HNVIIGGAVFGYIAGFGFYFPKAFGFKLHEGWGKAAFWFWISGFFVAFMPLYALGFMGMT
HHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLNATTNPEWVPYLYVAMFGAVMIAVGIACQLIQLYVSVRDRNKPENMCEHGDPWNAHT
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEE
LEWSTSSPPPFYNFAVLPKADCIDPFTEAKENGTAYKAPAKYEPIHMPNNTATGVVMGAL
EEECCCCCCCCCEEEECCCCCCCCCHHHHCCCCCEEECCCCCCCEECCCCCHHHHHHHHH
LTVFGFAMIWHIWWLAIASLAGTVIYFVIHAARDDQGYMVPVETIERIEAEQHKRLVAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCC
KIPASATRVETKLEQA
CCCCCHHHHHHHHHCC
>Mature Secondary Structure
MFGKLSWEAIPFHEPIVMVTISMIALGGLALFAAITYFKKWTYLWTEWLTSVDHKKIGVM
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YIIVAMVMLLRGFADAIMMRTQLAMATEGSPGYLPPEHYDQIFTAHGVIMIIFMAMPFFT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLMNLAVPLQIGARDVAFPFLNSLSFWLLVSGVVLINLSLGVGEFAKTGWVAYPPLSGLQ
HHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHCCCEECCCCCCCC
YSPGVGMDYYIWALQLSGLGTTLTGVNFLATVLKMRTPGMKLMDMPIFTWTCTWANVLIV
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCEEEEEHHHHHHHHH
ASFPILTATLALLTLDRYMDFHIFTNELGGNPMMYVNLFWAWGHPEVYILILPAFGIFSE
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEEEEEEEECCCCEEEEEECHHHHHHH
VISAFTGKKLFGHHSMIYASGAISVLGFMVWLHHFFTMGSGASVNAFFGLATMLISIPTG
HHHHHCCCHHHCCCHHEEECHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCH
VKLFNWLFTIYQGRLRFTSQVLWTLGFMVTFAIGGMTGVLLAIPGADFVLHNSLFVIAHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEEECCCCEEHHCCEEEEEHH
HNVIIGGAVFGYIAGFGFYFPKAFGFKLHEGWGKAAFWFWISGFFVAFMPLYALGFMGMT
HHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLNATTNPEWVPYLYVAMFGAVMIAVGIACQLIQLYVSVRDRNKPENMCEHGDPWNAHT
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEE
LEWSTSSPPPFYNFAVLPKADCIDPFTEAKENGTAYKAPAKYEPIHMPNNTATGVVMGAL
EEECCCCCCCCCEEEECCCCCCCCCHHHHCCCCCEEECCCCCCCEECCCCCHHHHHHHHH
LTVFGFAMIWHIWWLAIASLAGTVIYFVIHAARDDQGYMVPVETIERIEAEQHKRLVAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCC
KIPASATRVETKLEQA
CCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9868765 [H]