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The map label for this gene is yafC [H]

Identifier: 77460858

GI number: 77460858

Start: 5236043

End: 5236948

Strand: Direct

Name: yafC [H]

Synonym: Pfl01_4637

Alternate gene names: 77460858

Gene position: 5236043-5236948 (Clockwise)

Preceding gene: 77460856

Following gene: 77460859

Centisome position: 81.33

GC content: 64.02

Gene sequence:

>906_bases
ATGGATCTGTTCCAGTCGATGAGCGTGTACGTCAAGGTTGTGGAGTCCGGCAGCATGACGGCGGCCGCGCTGCAGTGCGA
AATGTCCACGACCATGGTGGGCAATCACCTGCGGGCGCTGGAGCAACGGCTCGGCGTGCAACTGTTGCAACGCACCACCC
GCCGCCAGCGGCTGACCGAGTTCGGCAGCGTTTACTACCAGCGCTGTCTGGAAGTACTTGGCCTGGTCGCCGACTCCGAA
CGCCTCGCCGAGCAGACGCTGGATGAACCGCGCGGCATCCTGCGGGTGACCGCGCCGCTGACCTTTGGTGTCGAACGCCT
GGCCCCGGCACTCAGTGAGTTTTCCCTGCAATGTCCGCAGGTCAAACTCGACGTGATCCTGACCAACCGCCGACCGGATC
TGCTGGAAAGCGGTCTCGACGTGGCCTTCCGACTGGGCCACTTCGACCAGTCCAACCTGATCGCCCGCCCCCTGATCGAC
TACACCCTGACGGTCTGCGCCTCCCCGGAGTACGTGGCCCGACGCGGCATGCCGCTCACCCCTGAGGAACTGCGTCAGCA
CGATTGCCTGTCCTTCGCCTACCCCGCTGGCGATGACTGGCAATCGGTGGAAAAACAGTGGCGCCTCAGCGGCCCGGACG
GCGAAATCATGGTCGACGTCAAAGGTCCGATGCTGATCAACAGCTCCGCCGGTCTGCATCAGGCTGCACGCACCGGTATG
GGCATCGTGATGCTGCCGGATGCGCTGGTGGAACAGGACCTGCGCGATGGCAGGCTGGTCGTCGTGATGCCTGACTACCA
GCCGCCGAACCGCCCGATGCATCTGCTCTATGCGCCGGATCGCTATCGGCTGCCTAAACTGCGTCGCTTCGTCGAGTTCG
CCCTGCAGATGTGGGGCAGACCGTAA

Upstream 100 bases:

>100_bases
CGGCAAACTCCAGCGAGGTGAGAGGTGCTGGCAGTATGGTTATCCACCTGAACTGGATAAACTCGGCAAAACTTCAATCA
TTTAAAAGCCGGGCTTGATA

Downstream 100 bases:

>100_bases
GCAACGCGACTACTGTTGGAAATACACCAGGGACGGGATCAAGGAATGAACAAAGACATTTCAATACGCGACCTCCTGCC
CACGGAAGTGGAGGCGGCAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MDLFQSMSVYVKVVESGSMTAAALQCEMSTTMVGNHLRALEQRLGVQLLQRTTRRQRLTEFGSVYYQRCLEVLGLVADSE
RLAEQTLDEPRGILRVTAPLTFGVERLAPALSEFSLQCPQVKLDVILTNRRPDLLESGLDVAFRLGHFDQSNLIARPLID
YTLTVCASPEYVARRGMPLTPEELRQHDCLSFAYPAGDDWQSVEKQWRLSGPDGEIMVDVKGPMLINSSAGLHQAARTGM
GIVMLPDALVEQDLRDGRLVVVMPDYQPPNRPMHLLYAPDRYRLPKLRRFVEFALQMWGRP

Sequences:

>Translated_301_residues
MDLFQSMSVYVKVVESGSMTAAALQCEMSTTMVGNHLRALEQRLGVQLLQRTTRRQRLTEFGSVYYQRCLEVLGLVADSE
RLAEQTLDEPRGILRVTAPLTFGVERLAPALSEFSLQCPQVKLDVILTNRRPDLLESGLDVAFRLGHFDQSNLIARPLID
YTLTVCASPEYVARRGMPLTPEELRQHDCLSFAYPAGDDWQSVEKQWRLSGPDGEIMVDVKGPMLINSSAGLHQAARTGM
GIVMLPDALVEQDLRDGRLVVVMPDYQPPNRPMHLLYAPDRYRLPKLRRFVEFALQMWGRP
>Mature_301_residues
MDLFQSMSVYVKVVESGSMTAAALQCEMSTTMVGNHLRALEQRLGVQLLQRTTRRQRLTEFGSVYYQRCLEVLGLVADSE
RLAEQTLDEPRGILRVTAPLTFGVERLAPALSEFSLQCPQVKLDVILTNRRPDLLESGLDVAFRLGHFDQSNLIARPLID
YTLTVCASPEYVARRGMPLTPEELRQHDCLSFAYPAGDDWQSVEKQWRLSGPDGEIMVDVKGPMLINSSAGLHQAARTGM
GIVMLPDALVEQDLRDGRLVVVMPDYQPPNRPMHLLYAPDRYRLPKLRRFVEFALQMWGRP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=34.4827586206897, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=34.9315068493151, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789639, Length=286, Percent_Identity=31.4685314685315, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1789440, Length=308, Percent_Identity=30.8441558441558, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87081978, Length=304, Percent_Identity=31.9078947368421, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=27.7397260273973, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1787589, Length=277, Percent_Identity=28.158844765343, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789173, Length=292, Percent_Identity=25.3424657534247, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788481, Length=303, Percent_Identity=25.7425742574257, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788706, Length=295, Percent_Identity=24.406779661017, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790011, Length=275, Percent_Identity=24, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790262, Length=249, Percent_Identity=26.9076305220884, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34002; Mature: 34002

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFQSMSVYVKVVESGSMTAAALQCEMSTTMVGNHLRALEQRLGVQLLQRTTRRQRLTE
CCHHHHHHHHHHHHCCCCCEEEHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGSVYYQRCLEVLGLVADSERLAEQTLDEPRGILRVTAPLTFGVERLAPALSEFSLQCPQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCHHHCHHHHHHHHHHHCCCCCC
VKLDVILTNRRPDLLESGLDVAFRLGHFDQSNLIARPLIDYTLTVCASPEYVARRGMPLT
EEEEEEEECCCHHHHHHCCHHEEHCCCCCCCCCHHHHHHHHHHHEECCCHHHHHCCCCCC
PEELRQHDCLSFAYPAGDDWQSVEKQWRLSGPDGEIMVDVKGPMLINSSAGLHQAARTGM
HHHHHHHCCCEEECCCCCCHHHHHHHEECCCCCCCEEEEECCCEEECCCCCHHHHHHHCC
GIVMLPDALVEQDLRDGRLVVVMPDYQPPNRPMHLLYAPDRYRLPKLRRFVEFALQMWGR
CEEECCHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCC
P
C
>Mature Secondary Structure
MDLFQSMSVYVKVVESGSMTAAALQCEMSTTMVGNHLRALEQRLGVQLLQRTTRRQRLTE
CCHHHHHHHHHHHHCCCCCEEEHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGSVYYQRCLEVLGLVADSERLAEQTLDEPRGILRVTAPLTFGVERLAPALSEFSLQCPQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCHHHCHHHHHHHHHHHCCCCCC
VKLDVILTNRRPDLLESGLDVAFRLGHFDQSNLIARPLIDYTLTVCASPEYVARRGMPLT
EEEEEEEECCCHHHHHHCCHHEEHCCCCCCCCCHHHHHHHHHHHEECCCHHHHHCCCCCC
PEELRQHDCLSFAYPAGDDWQSVEKQWRLSGPDGEIMVDVKGPMLINSSAGLHQAARTGM
HHHHHHHCCCEEECCCCCCHHHHHHHEECCCCCCCEEEEECCCEEECCCCCHHHHHHHCC
GIVMLPDALVEQDLRDGRLVVVMPDYQPPNRPMHLLYAPDRYRLPKLRRFVEFALQMWGR
CEEECCHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]