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The map label for this gene is hscB

Identifier: 77460830

GI number: 77460830

Start: 5209713

End: 5210234

Strand: Reverse

Name: hscB

Synonym: Pfl01_4609

Alternate gene names: 77460830

Gene position: 5210234-5209713 (Counterclockwise)

Preceding gene: 77460831

Following gene: 77460829

Centisome position: 80.92

GC content: 59.58

Gene sequence:

>522_bases
GTGGGTATTCCTTGTCATTTCGCTTTATTCGAGCTGCAACCGGGCTTTCGTCTGGATCTCGAGCAGTTGGCCACGCGCTA
TCGTGAGCTGGCGCGCGGTGTTCATCCTGACCGCTTTGCCGATGCTTCCGAGCGCGAGCAGCGGTCAGCGCTGGAGCAGT
CTGCGCGGCTCAACGATGCCTACCAGACACTCAAGAGTCCGGCCCAGCGTGCACGCTACCTGCTGACCATCAGCGGGCAT
GAAGTGCCGATGGAAGTTACCGTTCACGATCCCGAGTTTCTTCTGCAGCAGATGCAATGGCGCGAAGAGCTCGAAGATCT
GCAGGACAGTGCCGACCTGGCCGGTGTCGCGGCTTTCAAGCGTCGCCTGAAAACCGCCCAGGAAGAGCTCAACGAAAGCT
TCGCAGCCTGTTGGGATGATGCAGCGCAACGCGAACAGGCCGAACGCCTGATGCGGCGCATGCAGTTCCTCGACAAGCTC
ACCTACGAAGTGCGCCAGTTAGAAGAGCGCCTCGACGATTAA

Upstream 100 bases:

>100_bases
ACTTCGTCAAGGAAGGATTGAACGAAGGCTTCAAGTTCAACAATCCCAACGTACGCGGTGAATGTGGCTGCGGCGAAAGC
TTCAACATCTGAGGCTTGTC

Downstream 100 bases:

>100_bases
CCCAGTGCCGCTCCGGTCGCACGCCTGATATACAGATAAGTCCTGATCACGATGGCCCTACTGCAGATCGCCGAACCCGG
CCAAAGTCCTCAACCACACC

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MGIPCHFALFELQPGFRLDLEQLATRYRELARGVHPDRFADASEREQRSALEQSARLNDAYQTLKSPAQRARYLLTISGH
EVPMEVTVHDPEFLLQQMQWREELEDLQDSADLAGVAAFKRRLKTAQEELNESFAACWDDAAQREQAERLMRRMQFLDKL
TYEVRQLEERLDD

Sequences:

>Translated_173_residues
MGIPCHFALFELQPGFRLDLEQLATRYRELARGVHPDRFADASEREQRSALEQSARLNDAYQTLKSPAQRARYLLTISGH
EVPMEVTVHDPEFLLQQMQWREELEDLQDSADLAGVAAFKRRLKTAQEELNESFAACWDDAAQREQAERLMRRMQFLDKL
TYEVRQLEERLDD
>Mature_172_residues
GIPCHFALFELQPGFRLDLEQLATRYRELARGVHPDRFADASEREQRSALEQSARLNDAYQTLKSPAQRARYLLTISGHE
VPMEVTVHDPEFLLQQMQWREELEDLQDSADLAGVAAFKRRLKTAQEELNESFAACWDDAAQREQAERLMRRMQFLDKLT
YEVRQLEERLDD

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI50301234, Length=163, Percent_Identity=28.8343558282209, Blast_Score=77, Evalue=7e-15,
Organism=Escherichia coli, GI1788876, Length=174, Percent_Identity=39.0804597701149, Blast_Score=110, Evalue=4e-26,
Organism=Drosophila melanogaster, GI161084223, Length=166, Percent_Identity=28.9156626506024, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSCB_PSEPF (Q3K7A8)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_350337.1
- ProteinModelPortal:   Q3K7A8
- SMR:   Q3K7A8
- STRING:   Q3K7A8
- GeneID:   3713608
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_4609
- eggNOG:   COG1076
- HOGENOM:   HBG751004
- OMA:   LNDAYQT
- ProtClustDB:   PRK00294
- BioCyc:   PFLU205922:PFL_4609-MONOMER
- HAMAP:   MF_00682
- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:1.20.1280.20
- PANTHER:   PTHR11821
- SMART:   SM00271
- TIGRFAMs:   TIGR00714

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C; SSF46565 DnaJ_N; SSF47144 HSC20_C

EC number: NA

Molecular weight: Translated: 20270; Mature: 20139

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIPCHFALFELQPGFRLDLEQLATRYRELARGVHPDRFADASEREQRSALEQSARLNDA
CCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHH
YQTLKSPAQRARYLLTISGHEVPMEVTVHDPEFLLQQMQWREELEDLQDSADLAGVAAFK
HHHHHHHHHHHHHHEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLKTAQEELNESFAACWDDAAQREQAERLMRRMQFLDKLTYEVRQLEERLDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GIPCHFALFELQPGFRLDLEQLATRYRELARGVHPDRFADASEREQRSALEQSARLNDA
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHH
YQTLKSPAQRARYLLTISGHEVPMEVTVHDPEFLLQQMQWREELEDLQDSADLAGVAAFK
HHHHHHHHHHHHHHEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLKTAQEELNESFAACWDDAAQREQAERLMRRMQFLDKLTYEVRQLEERLDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA