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The map label for this gene is engA [H]

Identifier: 77460818

GI number: 77460818

Start: 5197859

End: 5199331

Strand: Reverse

Name: engA [H]

Synonym: Pfl01_4597

Alternate gene names: 77460818

Gene position: 5199331-5197859 (Counterclockwise)

Preceding gene: 77460819

Following gene: 77460817

Centisome position: 80.75

GC content: 60.49

Gene sequence:

>1473_bases
ATGGTTCCCGTAATCGCCCTGGTGGGCCGACCGAACGTCGGCAAGTCCACCTTGTTCAACCGCCTGACCAGGACTCGCGA
CGCCATCGTCGGCGACTTGTCCGGTCTGACCCGTGATCGCCAGTACGGTGAGGCCAAGTGGCAAGGGCGTTCCTACATTC
TGATCGACACCGGCGGTATCTCCGGTGACGAGCATGGTATGGACGAAAAAATGGCCGAGCAGTCGCTGCTGGCCATCGAA
GAAGCGGATGTCGTTCTGTTCCTGGTAGATGCCAAGGCCGGTTTCACCGCCGCCGACCAGATGATCGCCGAACACTTGCG
CAAACGTAACAAGCGCTCCCACGTGGTGGCCAACAAGGTCGACAACATCGACCCGGAAATGGCCCGCGCCGAATTCGCCC
CGCTGGGCATGGGCCACGCGATCCCGATCGCCGGCGCCCACGGTCGCGGCATCACGCAATTGCTGGAAGCCGCCCTGAGC
GACTTCCCGCGCGATGATGACGAGCCGGCCGAAGGTGAAGAGGAAGAAGTGGTCGCCGAAGGCGAGGAAGCCAAGCGCAT
TCCTGGGCCGAGCGAAAAAGACGGGATCAAGATTGCCATCATCGGCCGTCCGAACGTCGGCAAGTCGACCCTGGTTAACC
GCATGCTTGGTGAAGACCGGGTAATCGTCTACGACCAGCCCGGCACCACCCGCGACAGTATCTACATCCCGTTCGAGCGT
AACGACGAGAAGTACACGCTGATCGACACCGCCGGTGTGCGCAAGCGCGGCAAGATCCACGAAGAAGTCGAAAAATTCTC
CGTGGTCAAAACCCTGCAGGCGATCAAAGACGCCAACGTGGTGATCTTCGTGATGGACGCCCGCGAAGGCGTGGTCGATC
ACGACCTCAACCTGCTGGGCTTCGCCCTTGAAGCAGGTCGTGCGCTGGTGATCGCGATCAACAAATGGGACGGCATGACC
CCGAGCGAGCGCGACTTCGTGAAGGTCGAGCTACAGCGTCGGTTGTTCTTCGTTGACTTCGCCGATATCCACTTCATCTC
GGCACTGCACGGTACTGGCGTGGGCAACCTCTACGCCTCGGTGCAGAACTCGTTCAAGTCCGCGGTCACCCGCTGGCCGA
CCAGCCGCCTGACGCAGATTCTCGAAGACGCGGTCAGCGAGCACCAGCCGCCGATGGTCAACAGCCGCCGGATCAAGCTG
CGTTACGCTCACCTGGGTGGTGCGAACCCGCCGATCATCGTGATCCACGGCAACCAGATCGAGAAAGTGCCGAAGTCGTA
CGTGCGCTATCTGGAGAACACTTATCGCCGTGTGCTCAAACTGGTCGGTACGCCGATCCGTATCGAGTTCAAGGGTGGCG
AGAACCCGTACGAAGGCAACAAGAACACGCTGACCGACCGCCAGGTCAACAAGAAGCGTCGCTTGATGTCGCACAACAAG
AAAGCCAGCAAGAAGCGCCGCGACAAGAAGTAA

Upstream 100 bases:

>100_bases
CTTCTGCAGGGTTTGCAGCACCCACGGGTGTTGCCCCGAGCACCAGCCGCTGCCTCGCAGCGGCTTTTGTATTTTCTGAA
ATAACGAAGTGGAGAGCCGC

Downstream 100 bases:

>100_bases
GGTCGTTGCGAACAAAGAGAAGGGGCGCCGTTTGGCGCCCTTTTTTTATGGGCGCCGGATGGGCTATCCTCGGGCTCTCC
CGCGCCGTCGTCAGAGCCGG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MVPVIALVGRPNVGKSTLFNRLTRTRDAIVGDLSGLTRDRQYGEAKWQGRSYILIDTGGISGDEHGMDEKMAEQSLLAIE
EADVVLFLVDAKAGFTAADQMIAEHLRKRNKRSHVVANKVDNIDPEMARAEFAPLGMGHAIPIAGAHGRGITQLLEAALS
DFPRDDDEPAEGEEEEVVAEGEEAKRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEDRVIVYDQPGTTRDSIYIPFER
NDEKYTLIDTAGVRKRGKIHEEVEKFSVVKTLQAIKDANVVIFVMDAREGVVDHDLNLLGFALEAGRALVIAINKWDGMT
PSERDFVKVELQRRLFFVDFADIHFISALHGTGVGNLYASVQNSFKSAVTRWPTSRLTQILEDAVSEHQPPMVNSRRIKL
RYAHLGGANPPIIVIHGNQIEKVPKSYVRYLENTYRRVLKLVGTPIRIEFKGGENPYEGNKNTLTDRQVNKKRRLMSHNK
KASKKRRDKK

Sequences:

>Translated_490_residues
MVPVIALVGRPNVGKSTLFNRLTRTRDAIVGDLSGLTRDRQYGEAKWQGRSYILIDTGGISGDEHGMDEKMAEQSLLAIE
EADVVLFLVDAKAGFTAADQMIAEHLRKRNKRSHVVANKVDNIDPEMARAEFAPLGMGHAIPIAGAHGRGITQLLEAALS
DFPRDDDEPAEGEEEEVVAEGEEAKRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEDRVIVYDQPGTTRDSIYIPFER
NDEKYTLIDTAGVRKRGKIHEEVEKFSVVKTLQAIKDANVVIFVMDAREGVVDHDLNLLGFALEAGRALVIAINKWDGMT
PSERDFVKVELQRRLFFVDFADIHFISALHGTGVGNLYASVQNSFKSAVTRWPTSRLTQILEDAVSEHQPPMVNSRRIKL
RYAHLGGANPPIIVIHGNQIEKVPKSYVRYLENTYRRVLKLVGTPIRIEFKGGENPYEGNKNTLTDRQVNKKRRLMSHNK
KASKKRRDKK
>Mature_490_residues
MVPVIALVGRPNVGKSTLFNRLTRTRDAIVGDLSGLTRDRQYGEAKWQGRSYILIDTGGISGDEHGMDEKMAEQSLLAIE
EADVVLFLVDAKAGFTAADQMIAEHLRKRNKRSHVVANKVDNIDPEMARAEFAPLGMGHAIPIAGAHGRGITQLLEAALS
DFPRDDDEPAEGEEEEVVAEGEEAKRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEDRVIVYDQPGTTRDSIYIPFER
NDEKYTLIDTAGVRKRGKIHEEVEKFSVVKTLQAIKDANVVIFVMDAREGVVDHDLNLLGFALEAGRALVIAINKWDGMT
PSERDFVKVELQRRLFFVDFADIHFISALHGTGVGNLYASVQNSFKSAVTRWPTSRLTQILEDAVSEHQPPMVNSRRIKL
RYAHLGGANPPIIVIHGNQIEKVPKSYVRYLENTYRRVLKLVGTPIRIEFKGGENPYEGNKNTLTDRQVNKKRRLMSHNK
KASKKRRDKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=489, Percent_Identity=60.3271983640082, Blast_Score=588, Evalue=1e-169,
Organism=Escherichia coli, GI2367268, Length=191, Percent_Identity=29.3193717277487, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788919, Length=215, Percent_Identity=28.8372093023256, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=213, Percent_Identity=28.6384976525822, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 54711; Mature: 54711

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPVIALVGRPNVGKSTLFNRLTRTRDAIVGDLSGLTRDRQYGEAKWQGRSYILIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCC
SGDEHGMDEKMAEQSLLAIEEADVVLFLVDAKAGFTAADQMIAEHLRKRNKRSHVVANKV
CCCCCCCHHHHHHHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
DNIDPEMARAEFAPLGMGHAIPIAGAHGRGITQLLEAALSDFPRDDDEPAEGEEEEVVAE
CCCCHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHC
GEEAKRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEDRVIVYDQPGTTRDSIYIPFER
CCHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEC
NDEKYTLIDTAGVRKRGKIHEEVEKFSVVKTLQAIKDANVVIFVMDAREGVVDHDLNLLG
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHH
FALEAGRALVIAINKWDGMTPSERDFVKVELQRRLFFVDFADIHFISALHGTGVGNLYAS
HHCCCCCEEEEEEECCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHCCCHHHHHHH
VQNSFKSAVTRWPTSRLTQILEDAVSEHQPPMVNSRRIKLRYAHLGGANPPIIVIHGNQI
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCEEEEECCHH
EKVPKSYVRYLENTYRRVLKLVGTPIRIEFKGGENPYEGNKNTLTDRQVNKKRRLMSHNK
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCH
KASKKRRDKK
HHHHHHCCCC
>Mature Secondary Structure
MVPVIALVGRPNVGKSTLFNRLTRTRDAIVGDLSGLTRDRQYGEAKWQGRSYILIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCC
SGDEHGMDEKMAEQSLLAIEEADVVLFLVDAKAGFTAADQMIAEHLRKRNKRSHVVANKV
CCCCCCCHHHHHHHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
DNIDPEMARAEFAPLGMGHAIPIAGAHGRGITQLLEAALSDFPRDDDEPAEGEEEEVVAE
CCCCHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHC
GEEAKRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEDRVIVYDQPGTTRDSIYIPFER
CCHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEC
NDEKYTLIDTAGVRKRGKIHEEVEKFSVVKTLQAIKDANVVIFVMDAREGVVDHDLNLLG
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHH
FALEAGRALVIAINKWDGMTPSERDFVKVELQRRLFFVDFADIHFISALHGTGVGNLYAS
HHCCCCCEEEEEEECCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHCCCHHHHHHH
VQNSFKSAVTRWPTSRLTQILEDAVSEHQPPMVNSRRIKLRYAHLGGANPPIIVIHGNQI
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCEEEEECCHH
EKVPKSYVRYLENTYRRVLKLVGTPIRIEFKGGENPYEGNKNTLTDRQVNKKRRLMSHNK
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCH
KASKKRRDKK
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA