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The map label for this gene is arcD [H]

Identifier: 77460606

GI number: 77460606

Start: 4943642

End: 4945069

Strand: Direct

Name: arcD [H]

Synonym: Pfl01_4385

Alternate gene names: 77460606

Gene position: 4943642-4945069 (Clockwise)

Preceding gene: 77460604

Following gene: 77460607

Centisome position: 76.78

GC content: 60.22

Gene sequence:

>1428_bases
ATGTCTGAAGCTCCCGGAAAACTACGACTAGGTGCACTGGTCGCGTTGGTAGTCGGCTCAATGATCGGTGGCGGGATATT
CTCTTTGCCACAAAACATGGCCGCCAGTGCCGATGTCGGCGCGGTACTGATTGGCTGGGCCATCACCGCTGTCGGCATGC
TCACCCTCGCTTTCGTCTTCCAAACCCTGGCCAATCGCAAGCCTGACCTGGACGGCGGTGTCTACGCCTACGCCAAGGCC
GGTTTCGGCGATTACATGGGTTTCTCTTCGGCCTGGGGTTACTGGATCAGTGCCTGGCTGGGCAACGTCGGTTACTTCGT
TCTGCTGTTCAGCACTCTCGGGTATTTTTTTCCGATTTTTGGGGAGGGCAACACCGTTGCAGCCGTGATCGGCGCCTCTG
TCCTGCTGTGGGGCGTGCACTTTCTGGTACTGCGCGGGATCAAGGAAGCGGCGTTCATCAACCTCGTGACCACCGTCGCC
AAGGTCGTGCCGCTGCTGCTGTTCGTATTGATCGCGATCTTCGCCTTCAAACTGGACATCTTCACCGCCGATATCTGGGG
CGTGAAAAACCCGGATCTGGGCAGCGTGATGAACCAGGTGCGCAACATGATGCTGGTCACCGTGTGGGTGTTCATCGGCA
TCGAAGGCGCGAGCATCTTCTCGGCCCGGGCGGAAAAACGTTCGGACGTCGGCAAGGCGACCGTGATCGGTTTCATCACC
GTGCTGCTGTTCCTGGTGCTGGTGAACGTGCTGTCGCTGGGCATCATGACTCAGCCGGAACTGGCAAAACTGCAGAACCC
GTCGATGGCCGCCGTGCTGGAACACGTGGTCGGTCACTGGGGCGCGGTGCTGATCAGCGTCGGTCTGATCATCTCGCTGC
TGGGGGCGTTGCTGTCGTGGGTGCTGCTGTGTGCGGAGATCATGTTCGCCGCTGCCAAAGACCACACCATGCCGGAGTTC
CTGCGCAAGGAAAACGCCAACCACGTGCCGGTCAACGCCCTGTGGCTGACCAACGCGATGGTGCAGCTGTTCCTGATCAT
CACTCTGTTTTCGGCCAGCACTTACCTGTCGCTGATCTACCTCGCCACTTCGATGATTCTGGTGCCGTACCTGTGGTCGG
CGGCCTACGCCCTGCTGCTGGCGGTGCGCGGCGAAAGCTACGAAGGCTTCGCGGCCGAACGGCGCAAGGACCTGATCATC
GGCGCCATCGCCCTGATCTATGCGGTGTGGCTGCTCTACGCCGGTGGCGTGAAGTACCTGCTGCTCTCGGCCCTGCTCTA
TGCCCCCGGCGCGATCCTGTTCGCCAAGGCCAAGCTCGAACTCAAACAACCGGTTTTCACCAACGTCGAGAAGCTGATTT
TCGCCGCAGTGGTCGTGGGCGCCCTGGTGGCTGCCTACGGACTGTATGACGGCTTCCTGACTCTGTAA

Upstream 100 bases:

>100_bases
ATTAACAATGGAATGTGACCATGCACTGATCTAAGTCAGCTGTTTGAAAAGCCAACAGAACTACGCTGTGAACTCTTCTC
TCCTGCAATGGAGTCATGCA

Downstream 100 bases:

>100_bases
TTGCCCAACGTTTTCACTCTGGAGGATCACCGAAATGACCACGGAAAAAGCTAAGTACGGCGTCCATTCCGAAGCCGGCA
AACTGCGCAAAGTCATGGTT

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSEAPGKLRLGALVALVVGSMIGGGIFSLPQNMAASADVGAVLIGWAITAVGMLTLAFVFQTLANRKPDLDGGVYAYAKA
GFGDYMGFSSAWGYWISAWLGNVGYFVLLFSTLGYFFPIFGEGNTVAAVIGASVLLWGVHFLVLRGIKEAAFINLVTTVA
KVVPLLLFVLIAIFAFKLDIFTADIWGVKNPDLGSVMNQVRNMMLVTVWVFIGIEGASIFSARAEKRSDVGKATVIGFIT
VLLFLVLVNVLSLGIMTQPELAKLQNPSMAAVLEHVVGHWGAVLISVGLIISLLGALLSWVLLCAEIMFAAAKDHTMPEF
LRKENANHVPVNALWLTNAMVQLFLIITLFSASTYLSLIYLATSMILVPYLWSAAYALLLAVRGESYEGFAAERRKDLII
GAIALIYAVWLLYAGGVKYLLLSALLYAPGAILFAKAKLELKQPVFTNVEKLIFAAVVVGALVAAYGLYDGFLTL

Sequences:

>Translated_475_residues
MSEAPGKLRLGALVALVVGSMIGGGIFSLPQNMAASADVGAVLIGWAITAVGMLTLAFVFQTLANRKPDLDGGVYAYAKA
GFGDYMGFSSAWGYWISAWLGNVGYFVLLFSTLGYFFPIFGEGNTVAAVIGASVLLWGVHFLVLRGIKEAAFINLVTTVA
KVVPLLLFVLIAIFAFKLDIFTADIWGVKNPDLGSVMNQVRNMMLVTVWVFIGIEGASIFSARAEKRSDVGKATVIGFIT
VLLFLVLVNVLSLGIMTQPELAKLQNPSMAAVLEHVVGHWGAVLISVGLIISLLGALLSWVLLCAEIMFAAAKDHTMPEF
LRKENANHVPVNALWLTNAMVQLFLIITLFSASTYLSLIYLATSMILVPYLWSAAYALLLAVRGESYEGFAAERRKDLII
GAIALIYAVWLLYAGGVKYLLLSALLYAPGAILFAKAKLELKQPVFTNVEKLIFAAVVVGALVAAYGLYDGFLTL
>Mature_474_residues
SEAPGKLRLGALVALVVGSMIGGGIFSLPQNMAASADVGAVLIGWAITAVGMLTLAFVFQTLANRKPDLDGGVYAYAKAG
FGDYMGFSSAWGYWISAWLGNVGYFVLLFSTLGYFFPIFGEGNTVAAVIGASVLLWGVHFLVLRGIKEAAFINLVTTVAK
VVPLLLFVLIAIFAFKLDIFTADIWGVKNPDLGSVMNQVRNMMLVTVWVFIGIEGASIFSARAEKRSDVGKATVIGFITV
LLFLVLVNVLSLGIMTQPELAKLQNPSMAAVLEHVVGHWGAVLISVGLIISLLGALLSWVLLCAEIMFAAAKDHTMPEFL
RKENANHVPVNALWLTNAMVQLFLIITLFSASTYLSLIYLATSMILVPYLWSAAYALLLAVRGESYEGFAAERRKDLIIG
AIALIYAVWLLYAGGVKYLLLSALLYAPGAILFAKAKLELKQPVFTNVEKLIFAAVVVGALVAAYGLYDGFLTL

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=465, Percent_Identity=46.2365591397849, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI2367353, Length=420, Percent_Identity=28.5714285714286, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1790575, Length=387, Percent_Identity=27.6485788113695, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786908, Length=455, Percent_Identity=24.6153846153846, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51057; Mature: 50925

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAPGKLRLGALVALVVGSMIGGGIFSLPQNMAASADVGAVLIGWAITAVGMLTLAFVF
CCCCCCCHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QTLANRKPDLDGGVYAYAKAGFGDYMGFSSAWGYWISAWLGNVGYFVLLFSTLGYFFPIF
HHHHCCCCCCCCCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
GEGNTVAAVIGASVLLWGVHFLVLRGIKEAAFINLVTTVAKVVPLLLFVLIAIFAFKLDI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTADIWGVKNPDLGSVMNQVRNMMLVTVWVFIGIEGASIFSARAEKRSDVGKATVIGFIT
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHH
VLLFLVLVNVLSLGIMTQPELAKLQNPSMAAVLEHVVGHWGAVLISVGLIISLLGALLSW
HHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLCAEIMFAAAKDHTMPEFLRKENANHVPVNALWLTNAMVQLFLIITLFSASTYLSLIY
HHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATSMILVPYLWSAAYALLLAVRGESYEGFAAERRKDLIIGAIALIYAVWLLYAGGVKYL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LLSALLYAPGAILFAKAKLELKQPVFTNVEKLIFAAVVVGALVAAYGLYDGFLTL
HHHHHHHCCCHHEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEAPGKLRLGALVALVVGSMIGGGIFSLPQNMAASADVGAVLIGWAITAVGMLTLAFVF
CCCCCCHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHCCCHHEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2158926; 10984043; 1311296 [H]